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John Haynes

Dr

 https://orcid.org/0000-0003-3075-1553

Accepting PhD Students

1988 …2021
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Personal profile

Biography

Position

Senior Lecturer
Faculty of Pharmacy and Pharmaceutical Sciences

Stem Cell Biology group leader
Medicinal Chemistry and Drug Action
Monash Institute of Pharmaceutical Sciences

Monash teaching commitment

Lecture in:

  • Bachelor of Pharmaceutical Sciences: renal physiology, pharmacology and second messenger signalling, Neurodegeneration (Parkinson's disease)
  • Bachelor of Pharmacy: renal physiology and diuretic action

Keywords

  • Neurodegeneration
  • Disease model development
  • Parkinson's disease
  • Alzheimer's Disease
  • Inflammation

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2002 2021

ICON: ICON Collaboration-Tracing health impacts of natural and added nutrients in foods – approach for next-generation validation of the function of foods

Bennett, L., Bucking, M., Kotthoff, M., McCaffrey, T., Robinson, A. & Haynes, J.

1/08/18 → 1/08/21

Project: Research

Use of hESC-derived models to identify new therapeutic targets for treatment of neurodegenerative diseases

Pouton, C. & Haynes, J.

1/05/18 → 30/06/19

Project: Research

Stem Cells Australia

Little, M., Kilpatrick, T., Gardner, D., Hilton, D., Polo, J., Hobbs, R., Bourne, J., Marcelle, C., Rosenthal, N., Stanley, E., Elefanty, A., Barberi, T., Gray, P., Cooper-White, J., Wainwight, B., Wolvetang, E., Nielsen, L., Bartlett, P. F., Wells, C., Harvey, R., Graham, R., Palpant, N., Alexander, W. S., Laslett, A., Nilsson, S., Haylock, D., Grimmond, S., McDonald, V., Abud, H., Currie, P., Haynes, J., Janovjak, H., Martino, M. & Merson, T.

Australian Research Council (ARC), Monash University – Internal University Contribution

1/01/11 → 31/12/19

Project: Research

Dysregulation of focal adhesion kinase in Alport Syndrome patients

Haynes, J. & Ricardo, S.

4/01/17 → 23/12/18

Project: Research

Optimizing the differentiation and expansion of microglial progenitors from human pluripotent stem cells for the study and treatment of neurological disease

Pouton, C. & Haynes, J.

National Health & Medical Research Council (NHMRC)

1/07/15 → 30/06/18

Project: Research

Research Output 1988 2018

Acute or Delayed Systemic Administration of Human Amnion Epithelial Cells Improves Outcomes in Experimental Stroke

Evans, M. A., Lim, R., Kim, H. A., Chu, H. X., Gardiner-Mann, C. V., Taylor, K. W. E., Chan, C. T., Brait, V. H., Lee, S., Dinh, Q. N., Vinh, A., Phan, T. G., Srikanth, V. K., Ma, H., Arumugam, T. V., Fann, D. Y., Poh, L., Hunt, C. P. J., Pouton, C. W., Haynes, J. M. & 12 othersSelemidis, S., Kwan, W., Teo, L., Bourne, J. A., Neumann, S., Young, S., Gowing, E. K., Drummond, G. R., Clarkson, A. N., Wallace, E. M., Sobey, C. G. & Broughton, B. R. S., 1 Mar 2018, In : Stroke. 49, 3, p. 700-709 10 p.

Research output: Contribution to journal › Article › Research › peer-review

Increased cardiomyocyte alignment and intracellular calcium transients using micropatterned and drug-releasing poly(glycerol sebacate) elastomers

Zhu, C., Rodda, A. E., Truong, V. X., Shi, Y., Zhou, K., Haynes, J. M., Wang, B., Cook, W. D. & Forsythe, J. S., 2018, In : ACS Biomaterials Science and Engineering. 4, 7, p. 2494-2504 11 p.

Research output: Contribution to journal › Article › Research › peer-review

Induced pluripotent stem cell-derived podocyte-like cells as models for assessing mechanisms underlying heritable disease phenotype: Initial studies using two alport syndrome patient lines indicate impaired potassium channel activity

Haynes, J. M., Selby, J. N., Vandekolk, T. H., Abad, I. P. L., Ho, J. K., Lieuw, W-L., Leach, K., Savige, J., Saini, S., Fisher, C. L. & Ricardo, S. D., 1 Nov 2018, In : Journal of Pharmacology and Experimental Therapeutics. 367, 2, p. 335-347 13 p.

Research output: Contribution to journal › Article › Research › peer-review

NKX2-5 regulates human cardiomyogenesis via a HEY2 dependent transcriptional network

Anderson, D. J., Kaplan, D. I., Bell, K. M., Koutsis, K., Haynes, J. M., Mills, R. J., Phelan, D. G., Qian, E. L., Leitoguinho, A. R., Arasaratnam, D., Labonne, T., Ng, E. S., Davis, R. P., Casini, S., Passier, R., Hudson, J. E., Porrello, E. R., Costa, M. W., Rafii, A., Curl, C. L. & 9 othersDelbridge, L. M., Harvey, R. P., Oshlack, A., Cheung, M. M., Mummery, C. L., Petrou, S., Elefanty, A. G., Stanley, E. G. & Elliott, D. A., 10 Apr 2018, In : Nature Communications. 9, 1, 13 p., 1373.

Research output: Contribution to journal › Article › Research › peer-review

Open Access
File

PI3K activation in neural stem cells drives tumorigenesis which can be ameliorated by targeting the cAMP response element binding protein

Daniel, P. M., Filiz, G., Brown, D. V., Christie, M., Waring, P. M., Zhang, Y., Haynes, J. M., Pouton, C., Flanagan, D., Vincan, E., Johns, T. G., Montgomery, K., Phillips, W. A. & Mantamadiotis, T., 1 Jan 2018, In : Neuro-Oncology. 20, 10, p. 1344-1355 12 p.

Research output: Contribution to journal › Article › Research › peer-review

Activities 2011 2011

  • 1 Submissions to industry or govt committees, commissions and inquiries

Medicinal Chemistry and Drug Action

John Haynes (Member)
29 Nov 2011

Activity: External Academic Engagement › Submissions to industry or govt committees, commissions and inquiries