John Funder

Professor

1976 …2018
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Research Output 1976 2018

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Article
2018

Setting up a primary aldosteronism program: an Australian experience

Yang, J. & Funder, J. W., Jun 2018, In : Chinese Journal of Endocrinology and Metabolism. 34, 6, p. 451-459 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2017
126 Citations (Scopus)

Outcomes after adrenalectomy for unilateral primary aldosteronism: an international consensus on outcome measures and analysis of remission rates in an international cohort

Williams, T. A., Lenders, J. W. M., Mulatero, P., Burrello, J., Rottenkolber, M., Adolf, C., Satoh, F., Amar, L., Quinkler, M., Deinum, J., Beuschlein, F., Kitamoto, K. K., Pham, U., Morimoto, R., Umakoshi, H., Prejbisz, A., Kocjan, T., Naruse, M., Stowasser, M., Nishikawa, T. & 5 others, Young, W. F., Gomez-Sanchez, C. E., Funder, J. W., Reincke, M. & for the Primary Aldosteronism Surgery Outcome (PASO) investigators, 1 Sep 2017, In : The Lancet Diabetes and Endocrinology. 5, 9, p. 689-699 11 p.

Research output: Contribution to journalArticleResearchpeer-review

2015
71 Citations (Scopus)

A meta-analysis of somatic KCNJ5 K(+) channel mutations in 1636 patients with an aldosterone-producing adenoma

Lenzini, L., Rossitto, G., Maiolino, G., Letizia, C., Funder, J. W. & Rossi, G. P., 2015, In : Journal of Clinical Endocrinology and Metabolism. 100, 8, p. 1089 - 1095 7 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Primary aldosteronism: new answers, new questions

Funder, J. W., 2015, In : Hormone and Metabolic Research. 47, 13, p. 935 - 940 6 p.

Research output: Contribution to journalArticleResearchpeer-review

17 Citations (Scopus)

Primary aldosteronism and salt

Funder, J. W., 2015, In : Pflugers Archiv-European Journal of Physiology. 467, 3, p. 587 - 594 8 p.

Research output: Contribution to journalArticleResearchpeer-review

2014
18 Citations (Scopus)

Acquired convergence of hormone signaling in breast cancer: ER and PR transition from functionally distinct in normal breast to predictors of metastatic disease

Hilton, H. N., Doan, T. B., Graham, J. D., Oakes, S. R., Silvestri, A., Santucci, N., Kantimm, S., Huschtscha, L. I., Ormandy, C. J., Funder, J. W., Simpson, E. R., Kuczek, E. S., Leedman, P. J., Tilley, W. D., Fuller, P. J., Muscat, G. E. O. & Clarke, C. L., 2014, In : Oncotarget. 5, 18, p. 8651 - 8664 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
10 Citations (Scopus)

Breast cancer prognosis predicted by nuclear receptor-coregulator networks

Doan, T. B., Eriksson, N. A., Graham, D., Funder, J. W., Simpson, E. R., Kuczek, E. S., Clyne, C., Leedman, P. J., Tilley, W. D., Fuller, P. J., Muscat, G. E. O. & Clarke, C. L., Jul 2014, In : Molecular Oncology. 8, 5, p. 998-1013 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
19 Citations (Scopus)

PRMT2 and RORλ expression are associated with breast cancer survival outcomes

Oh, T. G., Bailey, P., Dray, E., Smith, A. G., Goode, J., Eriksson, N., Funder, J. W., Fuller, P. J., Simpson, E. R., Tilley, W. D., Leedman, P. J., Clarke, C. L., Grimmond, S., Dowhan, D. H. & Muscat, G. E. O., 2014, In : Molecular Endocrinology. 28, 7, p. 1166-1185 20 p.

Research output: Contribution to journalArticleResearchpeer-review

18 Citations (Scopus)

Role of androgens in sex differences in cardiac damage during myocardial infarction

Le, T. Y. L., Ashton, A. W., Mardini, M., Stanton, P. G., Funder, J. W., Handelsman, D. J. & Mihailidou, A. S., Feb 2014, In : Endocrinology. 155, 2, p. 568-575 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2010
23 Citations (Scopus)

Activation of mineralocorticoid receptors by exogenous glucocorticoids and the development of cardiovascular inflammatory responses in adrenalectomized rats

Young, M. J., Morgan, J., Brolin, K., Fuller, P. J. & Funder, J. W., Jun 2010, In : Endocrinology. 151, 6, p. 2622-2628 7 p.

Research output: Contribution to journalArticleResearchpeer-review

2009
184 Citations (Scopus)

Deletion of mineralocorticoid receptors from macrophages protects against deoxycorticosterone/salt-induced cardiac fibrosis and increased blood pressure

Rickard, A., Morgan, J., Tesch, G. H., Funder, J. W., Fuller, P. J. & Young, M. J., 2009, In : Hypertension. 54, 3, p. 537 - 543 7 p.

Research output: Contribution to journalArticleResearchpeer-review

31 Citations (Scopus)

Mediators of mineralocorticoid receptor-induced profibrotic inflammatory responses in the heart

Wilson, P., Morgan, J., Funder, J. W., Fuller, P. J. & Young, M. J., May 2009, In : Clinical Science. 116, 9, p. 731-739 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2007
19 Citations (Scopus)

Does glucocorticoid receptor blockade exacerbate tissue damage after mineralocorticoid/salt administration?

Rickard, A. J., Funder, J. W., Morgan, J., Fuller, P. J. & Young, M. J., Oct 2007, In : Endocrinology. 148, 10, p. 4829-4835 7 p.

Research output: Contribution to journalArticleResearchpeer-review

2006
33 Citations (Scopus)

Mineralocorticoid receptor blockade but not steroid withdrawal reverses renal fibrosis in deoxycorticosterone/salt rats

Lam, E., Funder, J. W., Nikolic-Paterson, D. J., Fuller, P. J. & Young, M. J., 2006, In : Endocrinology. 147, 7, p. 3623 - 3629 7 p.

Research output: Contribution to journalArticleResearchpeer-review

2005
7 Citations (Scopus)

Glucocorticoid responses to stress in castrate and testosterone-replaced rams

Dawood, T., Williams, M. R. I., Fullerton, M. J., Myles, K., Schuijers, J., Funder, J. W., Sudhir, K. & Komesaroff, P. A., 2005, In : Regulatory Peptides. 125, 1-3, p. 47 - 53 7 p.

Research output: Contribution to journalArticleResearchpeer-review

17 Citations (Scopus)

Mineralocorticoid-receptor blockade, hypertension and heart failure.

Funder, J. W., 2005, In : Nature Clinical Practice Endocrinology & Metabolism. 1, 1, p. 4 - 5 2 p.

Research output: Contribution to journalArticleResearchpeer-review

2004
101 Citations (Scopus)

Dehydroepiandrosterone Increases Endothelial Cell Proliferation in Vitro and Improves Endothelial Function in Vivo by Mechanisms Independent of Androgen and Estrogen Receptors

Williams, M. R. I., Dawood, T., Ling, S., Dai, A., Lew, R. M., Myles, K., Funder, J. W., Sudhir, K. & Komesaroff, P. A., 2004, In : Journal of Clinical Endocrinology and Metabolism. 89, 9, p. 4708 - 4715 8 p.

Research output: Contribution to journalArticleResearchpeer-review

91 Citations (Scopus)

Eplerenone, but not steroid withdrawal, reverses cardiac fibrosis in deoxycorticosterone/salt-treated rats

Young, M. & Funder, J. W., 1 Jul 2004, In : Endocrinology. 145, 7, p. 3153-3157 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
2003
106 Citations (Scopus)

Early inflammatory responses in experimental cardiac hypertrophy and fibrosis: Effects of 11β-hydroxysteroid dehydrogenase inactivation

Young, M. J., Moussa, L., Dilley, R. & Funder, J. W., 1 Mar 2003, In : Endocrinology. 144, 3, p. 1121-1125 5 p.

Research output: Contribution to journalArticleResearchpeer-review

43 Citations (Scopus)

Mineralocorticoid action and sodium-hydrogen exchange: Studies in experimental cardiac fibrosis

Young, M. & Funder, J., 1 Sep 2003, In : Endocrinology. 144, 9, p. 3848-3851 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
2002
122 Citations (Scopus)

Dehydroepiandrosterone Inhibits Human Vascular Smooth Muscle Cell Proliferation Independent of ARs and ERs

Williams, M. R. I., Ling, S., Dawood, T., Hashimura, K., Dai, A., Li, H., Liu, J-P., Funder, J. W., Sudmir, K. & Komesaroff, P., 2002, In : Journal of Clinical Endocrinology and Metabolism. 87, 1, p. 176 - 181 6 p.

Research output: Contribution to journalArticleResearchpeer-review

72 Citations (Scopus)

Telomerase activation causes vascular smooth muscle cell proliferation in genetic hypertension

Cao, Y., Li, H., Mu, F-T., Ebisui, O., Funder, J. W. & Liu, J-P., 2002, In : FASEB Journal. 16, 1, p. 96 - 98 3 p.

Research output: Contribution to journalArticleResearchpeer-review

2001
103 Citations (Scopus)

Cardiac steroidogenesis in the normal and failing heart

Young, M. J., Clyne, C. D., Cole, T. J. & Funder, J. W., 2001, In : Journal of Clinical Endocrinology and Metabolism. 86, 11, p. 5121-5126 6 p.

Research output: Contribution to journalArticleResearchpeer-review

29 Citations (Scopus)

Dynamin II regulates hormone secretion in neuroendocrine cells

Yang, Z., Li, H., Chai, Z., Fullerton, M. J., Cao, Y., Toh, B. H., Funder, J. & Liu, J-P., 2001, In : Journal of Biological Chemistry. 276, 6, p. 4251 - 4260 10 p.

Research output: Contribution to journalArticleResearchpeer-review

75 Citations (Scopus)

GRKO mice express an aberrant dexamethasone-binding glucocorticoid receptor, but are profoundly glucocorticoid resistant

Cole, T. J., Myles, K., Purton, J. F., Brereton, P. S., Solomon, N. M., Godfrey, D. I. & Funder, J., 2001, In : Molecular and Cellular Endocrinology. 173, p. 193 - 202 10 p.

Research output: Contribution to journalArticleResearchpeer-review

129 Citations (Scopus)

The serum- and glucocorticoid-induced kinase is a physiological mediator of aldosterone action

Bhargava, A., Fullerton, M. J., Myles, K., Purdy, T. M., Funder, J. W., Pearce, D. & Cole, T. J., 2001, In : Endocrinology. 142, 4, p. 1587 - 1594 8 p.

Research output: Contribution to journalArticleResearchpeer-review

1999
11 Citations (Scopus)

Aromatase inhibition alters vascular reactivity and arterial compliance in men: A possible vascular role for endogenous sex hormones in males

Komesaroff, P. A., Murray, R., Rajkumar, C., Esler, M. D., Jennings, G. L., Dart, A. M., Funder, J. W. & Sudhir, K., 1 Jan 1999, In : Australian and New Zealand Journal of Medicine. 29, 2, p. 265-267 3 p.

Research output: Contribution to journalArticleResearchpeer-review

1998
53 Citations (Scopus)

Effects of estrogen and estrous cycle on glucocorticoid and catecholamine responses to stress in sheep

Komesaroff, P. A., Esler, M., Clarke, I. J., Fullerton, M. J. & Funder, J. W., 1 Oct 1998, In : American Journal of Physiology - Endocrinology and Metabolism. 275, 4 38-4, p. E671-E678 8 p.

Research output: Contribution to journalArticleResearchpeer-review

1997
22 Citations (Scopus)

Mineralocorticoid Receptors, Salt, and Hypertension

Funder, J. W., Krozowski, Z., Myles, K., Sato, A., Sheppard, K. E. & Young, M., 1 Dec 1997, In : Recent Progress in Hormone Research. 52, p. 247-260 14 p.

Research output: Contribution to journalArticleResearchpeer-review

1996
157 Citations (Scopus)

Estrogen enhances basal nitric oxide release in the forearm vasculature in perimenopausal women

Sudhir, K., Jennings, G. L., Funder, J. W. & Komesaroff, P. A., 1 Jan 1996, In : Hypertension. 28, 3, p. 330-334 5 p.

Research output: Contribution to journalArticleResearchpeer-review

29 Citations (Scopus)

Mineralocorticoids, salt, hypertension: Effects on the heart

Young, M. J. & Funder, J. W., Apr 1996, In : Steroids. 61, 4, p. 233-235 3 p.

Research output: Contribution to journalArticleResearchpeer-review

90 Citations (Scopus)
1995
236 Citations (Scopus)

Determinants of cardiac fibrosis in experimental hypermineralocorticoid states

Young, M., Head, G. & Funder, J., 1995, In : American Journal of Physiology - Endocrinology and Metabolism. 269, 4 32-4

Research output: Contribution to journalArticleResearchpeer-review

62 Citations (Scopus)

The R337C mutation generates a high Km 11 β-hydroxysteroid dehydrogenase type II enzyme in a family with apparent mineralocorticoid excess

Obeyesekere, V. R., Ferrari, P., Andrews, R. K., Wilson, R. C., New, M. I., Funder, J. W. & Krozowski, Z. S., 1 Jan 1995, In : Journal of Clinical Endocrinology and Metabolism. 80, 11, p. 3381-3383 3 p.

Research output: Contribution to journalArticleResearchpeer-review

1994
17 Citations (Scopus)

6 Mineralocorticoid resistance

Komesaroff, P. A., Funder, J. W. & Fuller, P. J., 1994, In : Bailliere's Clinical Endocrinology and Metabolism. 8, 2, p. 333-355 23 p.

Research output: Contribution to journalArticleResearchpeer-review

44 Citations (Scopus)

Differential glucocorticoid effects on catecholamine responses to stress

Komesaroff, P. A. & Funder, J. W., 1 Jan 1994, In : American Journal of Physiology - Endocrinology and Metabolism. 266, 1 29-1

Research output: Contribution to journalArticleResearchpeer-review

406 Citations (Scopus)

Mineralocorticoids, hypertension, and cardiac fibrosis

Young, M., Fullerton, M., Dilley, R. & Funder, J., 1 Jan 1994, In : Journal of Clinical Investigation. 93, 6, p. 2578-2583 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
1993
2 Citations (Scopus)

Characterization of immunoreactive AVP in the ovine hypothalamo-pituitary axis

Shen, P. J., Clarke, I. J., Funder, J. W. & Smith, A. I., 1 Jan 1993, In : Peptides. 14, 4, p. 815-820 6 p.

Research output: Contribution to journalArticleResearchpeer-review

1991
1 Citation (Scopus)

Distribution, Isolation and Sequence Analysis of the C‐Terminal Heptapeptide of Pro‐Enkephalin A (YGGFMRF) from the Ovine Median Eminence

Giraud, A. S., Clarke, I. J., Rundle, S. E., Parker, L. M., Funder, J. W., Simpson, R. J. & Smith, A. I., 1 Jan 1991, In : Journal of Neuroendocrinology. 3, 2, p. 215-220 6 p.

Research output: Contribution to journalArticleResearchpeer-review

29 Citations (Scopus)

Evidence that the central noradrenergic and adrenergic pathways activate the hypothalamic-pituitary-adrenal axis in the sheep

Liu, J. P., Clarke, I. J., Funder, J. W. & Engler, D., 1 Jan 1991, In : Endocrinology. 129, 1, p. 200-209 10 p.

Research output: Contribution to journalArticleResearchpeer-review

32 Citations (Scopus)

Molecular cloning and sequencing of a guinea-pig pro-opiomelanocortin cDNA

Keightley, M. C., Funder, J. W. & Fuller, P. J., 1991, In : Molecular and Cellular Endocrinology. 82, 1, p. 89-98 10 p.

Research output: Contribution to journalArticleResearchpeer-review

46 Citations (Scopus)

Plasma beta-endorphin and adrenocorticotrophin in young horses in training.

McCarthy, R. N., Jeffcott, L. B., Funder, J. W., Fullerton, M. & Clarke, I. J., 1 Jan 1991, In : Australian Veterinary Journal. 68, 11, p. 359-361 3 p.

Research output: Contribution to journalArticleResearchpeer-review

1990
16 Citations (Scopus)

Adrenocorticotropin responses to endogenous and exogenous secretagogues in the sheep: Specificity of glucocorticoid action

Canny, B. J., Clarke, I. J. & Funder, J. W., 1 Jan 1990, In : Neuroendocrinology. 51, 2, p. 181-189 9 p.

Research output: Contribution to journalArticleResearchpeer-review

29 Citations (Scopus)

Arginine vasopressin and corticotropin releasing factor: Binding to ovine anterior pituitary membranes

Shen, P. J., Clarke, I. J., Canny, B. J., Funder, J. W. & Smith, A. I., 1 Jan 1990, In : Endocrinology. 127, 5, p. 2085-2089 5 p.

Research output: Contribution to journalArticleResearchpeer-review

1989
111 Citations (Scopus)

Arginine vasopressin is a much more potent stimulus to acth release from ovine anterior pituitary cells than ovine corticotropin-releasing factor: 1. In vitro studies

Familari, M., Smith, A. I., Smith, R. & Funder, J. W., 1 Jan 1989, In : Neuroendocrinology. 50, 2, p. 152-157 6 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Effect of ethane dimethane sulphonate on proopiomelanocortin (POMC) mRNA and POMC-derived peptides in the rat testis

Li, H., Risbridger, G. P., Funder, J. W. & Clements, J. A., 1989, In : Molecular and Cellular Endocrinology. 65, 1-2, p. 203-207 5 p.

Research output: Contribution to journalArticleResearchpeer-review

40 Citations (Scopus)

Evidence for an ultradian secretion of adrenocorticotropin, β-endorphin and α-melanocyte-stimulating hormone by the ovine anterior and intermediate pituitary

Engler, D., Pham, T., Fullerton, M. J., Clarke, I. J. & Funder, J. W., 1 Jan 1989, In : Neuroendocrinology. 49, 4, p. 349-360 12 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Generation of met-enkephalin arg6phe7 immunoreactivity by proteolytic cleavage of mammalian plasma precursors by pepsin

Giraud, A. S., Parker, L., Reichman, C., Familari, M., Smith, A. I. & Funder, J., 1 Jan 1989, In : Endocrinology. 124, 4, p. 1711-1716 6 p.

Research output: Contribution to journalArticleResearchpeer-review