Projects per year
Personal profile
Biography
In 1990 I set up a neuropsychology research unit, initially to study disorders of attention following stroke (unilateral neglect or hemi-inattention) and disorders of movement in the neurodegenerative disorders Parkinson's and Huntington's diseases.
To that end I developed a range of novel devices and paradigms, including a programmable serial choice-reaction-time device (now adopted for a major international multi-site study into the preclinical development of Huntington's disease), and a vibrotactile choice reaction time device to extend the classic Posner paradigm into the tactual modality. I have also developed a wide range of cognitive tasks, perhaps the most important being the staged "arrows" task which assesses levels of inhbitory (frontostriatal) dyscontrol and is now being widely used in brain imaging.
Our original work with neurodegenerative disorders of the basal ganglia/frontostriatal system soon extended to dystonia, Alzheimer's disease and Friedreich ataxia; and to neurodevelopmental disorders of the frontostriatal system - Tourette's and Williams syndromes, obssessive-compulsive and attention-deficit-hyperactivity disorders, schizophrenia, autism (and, separately, Asperger's disorder). To these, we next added compulsive gambling, addictive behaviours, inhibitory dyscontrol with violent offending, and depression (melancholic vs. nonmelancholic). Latterly, we have also addressed fragile X, and are attempting to assess the relative contributions of the frontostriatal and the frontocerebellar systems to the sequencing and fine control of movement in health and disease.
Separately from the above, my students have been working on synaesthesia, phantom limb phenomena, and empathy for pain.
Since 1990 I have authored or co-authored 4 major books (another 4 before then), 20 invited book chapters and 276 journal articles. The latter include 2 in Nature, 1 in Science, 8 in Brain, 15 in J Neurol Neurosurgery and Psychiatry, 13 in Movement Disorders, and 6 in Experimental Brain Research.
Research interests
Experimental neuropsychology with special reference to the frontostriatal system and disorders of control, attention and movemement, i.e. the neurodegenerative disorders Parkinson's, Huntington's and Alzheimer's diseases, and the neurodevelopmental disorders Tourette's syndrome, obsessive-compulsive and attention-deficit-hyperactivity disorders, schizophrenia, autism and depression.
Friedreich's attaxia, Williams syndrome. Impulsivity and violent aggression, addiction and problem gambling. The evolution of language, praxis and tool use.
Synaesthesia, spatial representations, embodiment, mirror-neuron and phantom limb phenomena.
Community service
Regular ABC Science Unit broadcasts: Ockham's Razor (27 talks), Science Show, Health Report, Café Scientifique;
Frequent contributions to Australasian Science and Tirra Lirra (literary journal);
Reviewing Grant and Journal Submissions
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- disorders of attention and of fine motor control
- disorders of the frontocerebellar system
- disorders of the frontostriatal system
- neurodegenerative disorders
- neurodevelopmental disorders
- neurodevelopmental disorders inhibitory control basal ganglia frontostriatal system tourette's syndr
- phantom limb phenomena
- synaesthesia
Collaborations and top research areas from the last five years
Projects
- 13 Finished
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Are neurobehavioural and neuromotor impairments associated with FMR1 gene expansion?
Cornish, K., Bradshaw, J., Fielding, J., Karistianis, N., Iansek, R., Metcalfe, S., Trollor, J. N., Wen, W., Delatycki, M. B. & Hackett, A.
Australian Research Council (ARC), University of Melbourne, University of New South Wales (UNSW)
4/01/11 → 30/10/14
Project: Research
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Motor functioning in young people with attention deficit hyperactivity disorder - combined type: A three-dimensional motion analysis study
Rinehart, N., Bradshaw, J., Cornish, K., Iansek, R., Tonge, B., McGinley, J. L. & Murphy, A. T.
National Health and Medical Research Council (NHMRC) (Australia)
1/01/11 → 31/12/14
Project: Research
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Motor functioning in autism and Asperger's disorder: Furthering current neurobehavioural and clinical definitions
Rinehart, N., Bradshaw, J., Iansek, R., McGinley, J. L. & Tonge, B.
National Health and Medical Research Council (NHMRC) (Australia)
2/01/07 → 30/04/12
Project: Research
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Anomalies in global network connectivity associated with early recovery from alcohol dependence: A network transcranial magnetic stimulation and electroencephalography study
Naim-Feil, J., Fitzgerald, P. B., Rubinson, M., Lubman, D. I., Sheppard, D. M., Bradshaw, J. L., Levit-Binnun, N. & Moses, E., Mar 2022, In: Addiction Biology. 27, 2, 17 p., e13146.Research output: Contribution to journal › Article › Research › peer-review
Open Access5 Citations (Scopus) -
Degenerative Disorders of the Brain
Hocking, D. R., Bradshaw, J. L. & Fielding, J., 5 Apr 2019, Oxon, UK: Routledge. 276 p.Research output: Book/Report › Edited Book › peer-review
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Attentional Mechanisms in Autism, ADHD, and Autism-ADHD Using a Local–Global Paradigm
Gargaro, B. A., May, T., Tonge, B. J., Sheppard, D. M., Bradshaw, J. L. & Rinehart, N. J., 1 Dec 2018, In: Journal of Attention Disorders. 22, 14, p. 1320-1332 13 p.Research output: Contribution to journal › Article › Research › peer-review
12 Citations (Scopus) -
Reflections of a Neuropsychologist: Brushes with Brains
Bradshaw, J. L., 2018, 1st ed. London: Routledge. 276 p.Research output: Book/Report › Book › Other › peer-review
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Why our brain caves random noise
Bradshaw, J. L., Nov 2018, In: Australasian Science. 39, 6, p. 14-16 3 p.Research output: Contribution to journal › Article › Other › peer-review