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Research Output

  • 95 Article
  • 4 Chapter (Book)
  • 2 Comment / Debate
  • 1 Review Article
2020

Disruption of the Burkholderia pseudomallei two-component signal transduction system BbeR-BbeS leads to increased extracellular DNA secretion and altered biofilm formation

Alwis, P. A., Treerat, P., Gong, L., Deveson Lucas, D., Allwood, E. M., Prescott, M., Devenish, R. J., Adler, B. & Boyce, J. D., Mar 2020, In : Veterinary Microbiology. 242, 11 p., 108603.

Research output: Contribution to journalArticleResearchpeer-review

2019

Characterization of Hypermutator Pseudomonas aeruginosa Isolates from Patients with Cystic Fibrosis in Australia

Rees, V. E., Deveson Lucas, D. S., López-Causapé, C., Huang, Y., Kotsimbos, T., Bulitta, J. B., Rees, M. C., Barugahare, A., Peleg, A. Y., Nation, R. L., Oliver, A., Boyce, J. D. & Landersdorfer, C. B., 1 Apr 2019, In : Antimicrobial Agents and Chemotherapy. 63, 4, 11 p., e02538-18.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Comparable Efficacy and Better Safety of Double -Lactam Combination Therapy versus -Lactam plus Aminoglycoside in Gram-Negative Bacteria in Randomized, Controlled Trials

Jiao, Y., Moya, B., Chen, M. J., Zavascki, A. P., Tsai, H., Tao, X., Sutaria, D. S., Louie, A., Boyce, J. D., Lucas, D. D., Kim, T. H., Tsuji, B. T., Bonomo, R. A., Drusano, G. L. & Bulitta, J. B., Jul 2019, In : Antimicrobial Agents and Chemotherapy. 63, 7, 15 p., e00425-19.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Erratum: Correction for Kennan et al., "Genomic Evidence for a Globally Distributed, Bimodal Population in the Ovine Footrot Pathogen Dichelobacter nodosus" (mBio (2014) 5 5 (e01821-e01814) PII: e02560-19)

Kennan, R. M., Gilhuus, M., Frosth, S., Seemann, T., Dhungyel, O. P., Whittington, R. J., Boyce, J. D., Powell, D. R., Aspán, A., Jørgensen, H. J., Bulach, D. M. & Rood, J. I., 29 Oct 2019, In : mBio. 10, 5, 1 p.

Research output: Contribution to journalComment / DebateOtherpeer-review

Open Access

Mechanisms of Polymyxin Resistance

Moffatt, J. H., Harper, M. & Boyce, J. D., Jul 2019, Polymyxin Antibiotics: From Laboratory Bench to Bedside. Li, J., Nation, R. L. & Kaye, K. S. (eds.). Switzerland: Springer, p. 55-71 17 p. (Advances in Experimental Medicine and Biology; vol. 1145).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

3 Citations (Scopus)

Systematic identification and analysis of Acinetobacter baumannii type vi secretion system effector and immunity components

Lewis, J. M., Deveson Lucas, D., Harper, M. & Boyce, J. D., 30 Oct 2019, In : Frontiers in Microbiology. 10, 23 p., 2440.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2018

Combating Carbapenem-Resistant Acinetobacter baumannii by an Optimized Imipenem-plus-Tobramycin Dosage Regimen: Prospective Validation via Hollow-Fiber Infection and Mathematical Modeling

Landersdorfer, C. B., Yadav, R., Rogers, K. E., Kim, T. H., Shin, B. S., Boyce, J. D., Nation, R. L. & Bulitta, J. B., 1 Apr 2018, In : Antimicrobial Agents and Chemotherapy. 62, 4, 8 p., e02053-17.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Determination of the small RNA GcvB regulon in the Gram-negative bacterial pathogen Pasteurella multocida and identification of the GcvB seed binding region

Gulliver, E. L., Wright, A., Deveson, D., Megroz, M., Kleifeld, O., Schittenhelm, R. B., Powell, D. R., Seemann, T., Bulitta, J. B., Harper, M. & Boyce, J. D., 1 May 2018, In : Rna-A Publication of the Rna Society. 24, 5, p. 704-720 17 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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6 Citations (Scopus)

Emergence of high-level colistin resistance in an acinetobacter baumannii clinical isolate mediated by inactivation of the global regulator H-NS

Lucas, D. D., Crane, B., Wright, A., Han, M-L., Moffatt, J., Bulach, D., Gladman, S. L., Powell, D., Aranda, J., Seemann, T., Machado, D., Pacheco, T., Marques, T., Viveiros, M., Nation, R., Li, J., Harper, M. & Boyce, J. D., 1 Jul 2018, In : Antimicrobial Agents and Chemotherapy. 62, 7, 17 p., e02442-17.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

Identification of novel Acinetobacter baumannii type VI secretion system antibacterial effector and immunity pairs

Fitzsimons, T. C., Lewis, J. M., Wright, A., Kleifeld, O., Schittenhelm, R. B., Powell, D., Harper, M. & Boyce, J. D., 1 Aug 2018, In : Infection and Immunity. 86, 8, 23 p., e00297-18.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

Meropenem Combined with Ciprofloxacin Combats Hypermutable Pseudomonas aeruginosa from Respiratory Infections of Cystic Fibrosis Patients

Rees, V. E., Yadav, R., Rogers, K. E., Bulitta, J. B., Wirth, V., Oliver, A., Boyce, J. D., Peleg, A. Y., Nation, R. L. & Landersdorfer, C. B., 1 Nov 2018, In : Antimicrobial Agents and Chemotherapy. 62, 11, 12 p., e01150-18.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Optimization of a meropenem-tobramycin combination dosage regimen against hypermutable and nonhypermutable pseudomonas aeruginosa via mechanism-based modeling and the hollow-fiber infection model

Landersdorfer, C. B., Rees, V. E., Yadav, R., Rogers, K. E., Kim, T. H., Bergen, P. J., Cheah, S-E., Boyce, J. D., Peleg, A. Y., Oliver, A., Shin, B. S., Nation, R. L. & Bulitta, J. B., 1 Apr 2018, In : Antimicrobial Agents and Chemotherapy. 62, 4, 13 p., e02055-17.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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7 Citations (Scopus)

What’s the risk? Identifying potential human pathogens within grey-headed flying foxes faeces

Henry, R., Galbraith, P., Coutts, S., Prosser, T., Boyce, J. & McCarthy, D. T., 23 Jan 2018, In : PLoS ONE. 13, 1, 20 p., e0191301.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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4 Citations (Scopus)
2017

Characterization of two novel lipopolysaccharide phosphoethanolamine transferases in Pasteurella multocida and their role in resistance to cathelicidin-2

Harper, M., Wright, A., Michael, F. S., Li, J., Lucas, D. D., Ford, M., Adler, B., Cox, A. D. & Boyce, J. D., Nov 2017, In : Infection and Immunity. 85, 11, 16 p., e00557-17.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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3 Citations (Scopus)

Global Gene Expression Profile of Acinetobacter baumannii During Bacteremia

Murray, G. L., Tsyganov, K., Kostoulias, X. P., Bulach, D. M., Powell, D., Creek, D. J., Boyce, J. D., Paulsen, I. T. & Peleg, A. Y., 15 Feb 2017, In : Journal of Infectious Diseases. 215, 1, p. S52-S57

Research output: Contribution to journalArticleResearchpeer-review

18 Citations (Scopus)

The myriad properties of Pasteurella multocida lipopolysaccharide

Harper, M. & Boyce, J. D., 21 Aug 2017, In : Toxins. 9, 8, 21 p., 254.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
File
5 Citations (Scopus)
2016

Global metabolic analyses identify key differences in metabolite levels between polymyxin-susceptible and polymyxin-resistant Acinetobacter baumannii

Maifiah, M. H. M., Cheah, S-E., Johnson, M. D., Han, M., Boyce, J. D., Thamlikitkul, V., Forrest, A., Kaye, K. S., Hertzog, P., Purcell, A. W., Song, J., Velkov, T., Creek, D. J. & Li, J., 29 Feb 2016, In : Scientific Reports. 6, 17 p., 22287.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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16 Citations (Scopus)

Perturbation of the two-component signal transduction system, BprRS, results in attenuated virulence and motility defects in Burkholderia pseudomallei

Lazar Adler, N. R., Allwood, E. M., Deveson Lucas, D., Harrison, P., Watts, S., Dimitropoulos, A., Treerat, P., Alwis, P., Devenish, R. J., Prescott, M., Govan, B., Adler, B., Harper, M. & Boyce, J. D., 4 May 2016, In : BMC Genomics. 17, 17 p., 331.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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7 Citations (Scopus)

Polymyxin resistance in Acinetobacter baumannii: genetic mutations and transcriptomic changes in response to clinically relevant dosage regimens

Cheah, S-E., Johnson, M. D., Zhu, Y., Tsuji, B. T., Forrest, A., Bulitta, J., Boyce, J. D., Nation, R. L. & Li, J., 19 May 2016, In : Scientific Reports. 6, 11 p., 26233.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
19 Citations (Scopus)

Protective efficacy afforded by live Pasteurella multocida vaccines in chickens is independent of lipopolysaccharide outer core structure

Harper, M., John, M., Edmunds, M., Wright, A. A., Ford, M. E., Turni, C., Blackall, P. J., Cox, A. D., Adler, B. & Boyce, J. D., 2016, In : Vaccine. 34, 14, p. 1696 - 1703 8 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

RNA-seq analysis of virR and revR mutants of Clostridium perfringens

Low, L-Y., Harrison, P. F., Lin, Y-H., Boyce, J. D., Rood, J. I. & Cheung, J. K., 23 May 2016, In : BMC Genomics. 17, 14 p., 391.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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4 Citations (Scopus)
2015

Burkholderia pseudomallei type III secretion system cluster 3 ATPase BsaS, a chemotherapeutic target for small-molecule ATPase inhibitors

Gong, L., Lai, S., Treerat, P., Prescott, M., Adler, B., Boyce, J. D. & Devenish, R. J., 2015, In : Infection and Immunity. 83, 4, p. 1276 - 1285 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
9 Citations (Scopus)

Characterization of the lipopolysaccharide produced by Pasteurella multocida serovars 6, 7 and 16: identification of lipopolysaccharide genotypes L4 and L8

Harper, M., St Michael, F., Steen, J. A., John, M., Wright, A. L., van Dorsten, L., Vinogradov, E., Adler, B., Cox, A. D. & Boyce, J. D., 2015, In : Glycobiology. 25, 3, p. 294 - 302 9 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Comparative genomic analysis of asian haemorrhagic septicaemia-associated strains of pasteurella multocida identifies more than 90 haemorrhagic septicaemia-specific genes

Moustafa, A. M., Seemann, T., Gladman, S. L., Adler, B., Harper, M., Boyce, J. D. & Bennett, M. D., 2015, In : PLoS ONE. 10, 7, 16 p., e0130296.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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20 Citations (Scopus)

Development of a rapid multiplex PCR assay to genotype pasteurella multocida strains by use of the lipopolysaccharide outer core biosynthesis locus

Harper, M., John, M., Turni, C., Edmunds, M. L., St Michael, F., Adler, B., Blackall, P. J., Cox, A. D. & Boyce, J. D., 2015, In : Journal of Clinical Microbiology. 53, 2, p. 477 - 485 9 p.

Research output: Contribution to journalArticleResearchpeer-review

26 Citations (Scopus)

Novel approach to optimize synergistic carbapenem-aminoglycoside combinations against carbapenem-resistant Acinetobacter baumannii

Yadav, R., Landersdorfer, C. B., Nation, R. L., Boyce, J. D. & Bulitta, J. B., 2015, In : Antimicrobial Agents and Chemotherapy. 59, 4, p. 2286 - 2298 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
33 Citations (Scopus)

Synergistic killing of NDM-producing MDR Klebsiella pneumoniae by two 'old' antibiotics-polymyxin B and chloramphenicol

Abdul Rahim, N., Cheah, S-E., Johnson, M. D., Yu, H., Sidjabat, H. E., Boyce, J., Butler, M. S., Cooper, M. A., Fu, J., Paterson, D. L., Nation, R. L., Bergen, P. J., Velkov, T. & Li, J., 2015, In : Journal of Antimicrobial Chemotherapy. 70, 9, p. 2589-2597 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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36 Citations (Scopus)

The Burkholderia pseudomallei proteins BapA and BapC are secreted TTSS3 effectors and BapB levels modulate expression of BopE

Treerat, P., Alwis, P. A., D'Cruze, T. M., Cullinane, M., Vadivelu, J., Devenish, R. J., Prescott, M., Adler, B. & Boyce, J. D., 2015, In : PLoS ONE. 10, 12, 19 p., e0143916.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2 Citations (Scopus)

The transcriptomic response of Acinetobacter baumannii to colistin and doripenem alone and in combination in an in vitro pharmacokinetics/pharmacodynamics model

Henry, R. M., Crane, B. A., Powell, D. R., Deveson-Lucas, D. S., Li, Z., Aranda, J., Harrison, P. F., Nation, R. L., Adler, B., Harper, M., Boyce, J. D. & Li, J., 2015, In : Journal of Antimicrobial Chemotherapy. 70, 5, p. 1303 - 1313 11 p.

Research output: Contribution to journalArticleResearchpeer-review

32 Citations (Scopus)
2014

Biological cost of different mechanisms of colistin resistance and their impact on virulence in Acinetobacter baumannii

Beceiro, A., Moreno, A., Fernandez, N., Vallejo, J. A., Aranda, J., Adler, B., Harper, M., Boyce, J. D. & Bou, G., 2014, In : Antimicrobial Agents and Chemotherapy. 58, 1, p. 518 - 526 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
109 Citations (Scopus)

Genomic evidence for a Globally distributed, Bimodal population in the Ovine footrot pathogen dichelobacter nodosus

Kennan, R. M., Gilhuus, M., Frosth, S., Seemann, T., Dhungyel, O. P., Whittington, R. J., Boyce, J. D., Powell, D. R., Aspan, A., Jorgensen, H. J., Bulach, D. M. & Rood, J. I., 2014, In : mBio. 5, 5, p. 1 - 11 11 p., e01821-14.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
23 Citations (Scopus)

In silico prediction of Gallibacterium anatis pan-immunogens

Bager, R. J., Kudirkiene, E., de Piedade, I., Seemann, T., Nielsen, T. K., Pors, S. E., Mattsson, A. H., Boyce, J. D., Adler, B. & Bojesen, A. M., 2014, In : Veterinary Research. 45, 1, p. 1 - 12 12 p., 80.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
12 Citations (Scopus)

Structural analysis of lipopolysaccharide produced by Heddleston serovars 10, 11, 12 and 15 and the identification of a new Pasteurella multocida lipopolysaccharide outer core biosynthesis locus, L6

Harper, M., St Michael, F., John, M., Steen, J. A., van Dorsten, L., Parnas, H., Vinogradov, E., Adler, B., Cox, A. D. & Boyce, J. D., 2014, In : Glycobiology. 24, 7, p. 649 - 659 11 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)
2013
Open Access
19 Citations (Scopus)

Evolutionary analysis of Burkholderia pseudomallei identifies putative novel virulence genes, including a microbial regulator of host cell autophagy

Singh, A. P., Lai, S., Nandi, T., Chua, H. H., Ooi, W. F., Ong, C., Boyce, J. D., Adler, B., Devenish, R. J. & Tan, P., 2013, In : Journal of Bacteriology. 195, 24, p. 5487 - 5498 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
7 Citations (Scopus)

Identification of a DNA-damage-inducible regulon in Acinetobacter baumannii

Aranda, J., Poza, M., Shingu-Vazquez, M. A., Cortes, P., Boyce, J. D., Adler, B., Barbe, J. & Bou, G., 2013, In : Journal of Bacteriology. 195, 24, p. 5577 - 5582 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
17 Citations (Scopus)
35 Citations (Scopus)

Pasteurella multocida Heddleston serovar 3 and 4 strains share a common lipopolysaccharide biosynthesis locus but display both inter- and intrastrain lipopolysaccharide heterogeneity

Harper, M., St Michael, F., John, M., Vinogradov, E., Steen, J. A., van Dorsten, L., Steen, J. A., Turni, C., Blackall, P. J., Adler, B., Cox, A. D. & Boyce, J. D., 2013, In : Journal of Bacteriology. 195, 21, p. 4854 - 4864 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
20 Citations (Scopus)

Structure and biosynthetic locus of the lipopolysaccharide outer core produced by Pasteurella multocida serovars 8 and 13 and the identification of a novel phospho-glycero moiety

Harper, M., St Michael, F., Vinogradov, E., John, M., Steen, J. A., van Dorsten, L., Boyce, J. D., Adler, B. & Cox, A. D., 2013, In : Glycobiology. 23, 3, p. 286 - 294 9 p.

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)

The fimbrial protein FlfA from Gallibacterium anatis is a virulence factor and vaccine candidate

Bager, R., Nesta, B., Pors, S. E., Soriani, M., Serino, L., Boyce, J. D., Adler, B. & Bojesen, A. M., 2013, In : Infection and Immunity. 81, 6, p. 1964 - 1973 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
20 Citations (Scopus)
2012
6 Citations (Scopus)

Characterization of the lipopolysaccharide from Pasteurella multocida Heddleston serovar 9: identification of a proposed bi-functional dTDP-3-acetamido-3,6-dideoxy-alpha-D-glucose biosynthesis enzyme

Harper, M., St Michael, F., Vinogradov, E., John, M., Boyce, J. D., Adler, B. & Cox, A. D., 2012, In : Glycobiology. 22, 3, p. 332 - 344 13 p.

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)

Natural transformation of gallibacterium anatis

Kristensen, B. M., Sinha, S., Boyce, J. D., Bojesen, A. M., Mell, J. C. & Redfield, R. J., 2012, In : Applied and Environmental Microbiology. 78, 14, p. 4914 - 4922 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
19 Citations (Scopus)

Pasteurella multocida: diseases and pathogenesis

Wilkie, I. W., Harper, M., Boyce, J. D. & Adler, B., 2012, In : Current topics in microbiology and immunology. 361, p. 1 - 22 22 p.

Research output: Contribution to journalArticleResearchpeer-review

94 Citations (Scopus)

Pathogenomics of pasteurella multocida

Boyce, J. D., Seemann, T., Adler, B. & Harper, M., 2012, In : Current topics in microbiology and immunology. 361, p. 23 - 38 16 p.

Research output: Contribution to journalArticleResearchpeer-review

27 Citations (Scopus)

Screening of 71 P. multocida proteins for protective efficacy in a fowl cholera infection model and characterization of the protective antigen PlpE

Hatfaludi, T. Z., Al-Hasani, K., Gong, L., Boyce, J. D., Ford, M., Wilkie, I. W., Quinsey, N. S., Dunstone, M. A., Hoke, D. E. & Adler, B., 2012, In : PLoS ONE. 7, 7, 11 p., e39973.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
20 Citations (Scopus)

The key surface components of pasteurella multocida: capsule and lipopolysaccharide

Harper, M., Boyce, J. D. & Adler, B., 2012, In : Current topics in microbiology and immunology. 361, p. 39 - 51 13 p.

Research output: Contribution to journalArticleResearchpeer-review

24 Citations (Scopus)
2011
51 Citations (Scopus)