Projects per year
Personal profile
Biography
Professor Boyce is a group leader in the Department of Microbiology, Biomedicine Discovery Institute, Monash University. His research is focused on elucidating the molecular mechanisms of antibiotic resistance, bacterial pathogenesis and host immunity to infections. He works with a wide range of Gram-negative and Gram-positive pathogens including, Acinetobacter baumannii, Pasteurella multocida, Burkholderia pseudomallei, Pseudomonas aeruginosa, Dichelobacter nodosus and Clostridium perfringens. His specialty area of expertise is next generation high-throughput sequencing for bacterial genomics and transcriptomic analyses.
Professor Boyce is a founding member of the Centre to Impact AMR, and is helping to drive our community engagement and environmental engineering strategies.
Research interests
- Acinetobacter baumannii antibiotic resistance mechanisms
- How Acinetobacter baumannii uses its type VI secretion system to kill competitors
- Pasteurella multocida virulence mechanisms
- How small RNAs control gene expression and protein production in Gram-negative bacteria
- Novel antibiotic combinations for improved killing of Gram-negative multi-drug resistant pathogens
Monash teaching commitment
MIC3041
MIC3011
MIC3032
MOL2011
BMS1062
MED1022
MED2042
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- Acinetobacter Baumannii
- Pasteurella Multocida
- Pseudomonas Aeruginosa
- Burkholderia Pseudomallei
- Antibiotic resistance
- Bacteriology
- Bacteriology, vaccines
- Genomics
- Microbiology
Collaborations and top research areas from the last five years
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Role of Pasteurella surface polysaccharides in pathogenesis and immunity
Boyce, J., Harper, M. & Cox, A.
1/06/21 → 30/05/24
Project: Research
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Virulence Associated small RNAs in Acinetobacter baumannii
Peleg, A., Boyce, J., Vogel, J. & Short, F.
National Health and Medical Research Council (NHMRC) (Australia)
1/01/21 → 31/12/24
Project: Research
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Next-generation combination dosing strategies to combat resistant Acinetobacter baumannii
Bulitta, J., Boyce, J., Bonomo, R., Drusano, G. & Louie, A.
NIH - National Institutes of Health (United States of America)
8/11/17 → 31/10/23
Project: Research
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Co-opting bacterial weaponry: Manipulation of the Acinetobacter type VI secretion system for targeted killing of bacteria
Boyce, J., Harper, M. & Drinkwater, N.
1/01/19 → 31/12/22
Project: Research
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Combating Pseudomonas aeruginosa infections in paediatric patients with cystic fibrosis
Landersdorfer, C., Deveson, D., Boyce, J., Nation, R. & Oliver, A.
1/01/19 → 31/12/19
Project: Research
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Ceftolozane/tazobactam plus tobramycin against free-floating and biofilm bacteria of hypermutable Pseudomonas aeruginosa epidemic strains: Resistance mechanisms and synergistic activity
Agyeman, A. A., López-Causapé, C., Rogers, K. E., Lucas, D. D., Cortés-Lara, S., Gomis-Font, M. A., Fraile-Ribot, P., Figuerola, J., Lang, Y., Franklyn, E. R. T., Lee, W. L., Zhou, J., Zhang, Y., Bulitta, J. B., Boyce, J. D., Nation, R. L., Oliver, A. & Landersdorfer, C. B., Sept 2023, In: International Journal of Antimicrobial Agents. 62, 3, 10 p., 106887.Research output: Contribution to journal › Article › Research › peer-review
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Genome-Wide Investigation of Pasteurella multocida Identifies the Stringent Response as a Negative Regulator of Hyaluronic Acid Capsule Production
Smallman, T. R., Williams, G. C., Harper, M. & Boyce, J. D., Apr 2022, In: Microbiology Spectrum. 10, 2, 16 p., e00195-22.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
The Role and Targets of the RNA-Binding Protein ProQ in the Gram-Negative Bacterial Pathogen Pasteurella multocida
Gulliver, E. L., Sy, B. M., Wong, J. L., Deveson Lucas, D. S., Powell, D. R., Harper, M., Tree, J. J. & Boyce, J. D., Apr 2022, In: Journal of Bacteriology. 204, 4, p. 1-22 22 p.Research output: Contribution to journal › Article › Research › peer-review
2 Citations (Scopus) -
Combating Multidrug-Resistant Bacteria by Integrating a Novel Target Site Penetration and Receptor Binding Assay Platform Into Translational Modeling
Lang, Y., Shah, N. R., Tao, X., Reeve, S. M., Zhou, J., Moya, B., Sayed, A. R. M., Dharuman, S., Oyer, J. L., Copik, A. J., Fleischer, B. A., Shin, E., Werkman, C., Basso, K. B., Deveson Lucas, D., Sutaria, D. S., Mégroz, M., Kim, T. H., Loudon-Hossler, V., Wright, A., & 18 others , Apr 2021, In: Clinical Pharmacology & Therapeutics. 109, 4, p. 1000-1020 21 p.Research output: Contribution to journal › Article › Research › peer-review
6 Citations (Scopus) -
Pharmacodynamics of ceftazidime plus tobramycin combination dosage regimens against hypermutable Pseudomonas aeruginosa isolates at simulated epithelial lining fluid concentrations in a dynamic in vitro infection model
Tait, J. R., Bilal, H., Kim, T. H., Oh, A., Peleg, A. Y., Boyce, J. D., Oliver, A., Bergen, P. J., Nation, R. L. & Landersdorfer, C. B., Sept 2021, In: Journal of Global Antimicrobial Resistance. 26, p. 55-63 9 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access4 Citations (Scopus)
Press/Media
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NEW RESISTANCE MECHANISM IN THE OFTEN MULTIDRUG RESISTANT PATHOGEN ACINETOBACTER BAUMANNII
30/04/18
1 Media contribution
Press/Media: Research
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A$9.8 million fight against superbugs
Jian Li, William Neil Charman, Jiangning Song, Anthony Wayne Purcell, Paul John Hertzog, Darren John Creek, Roger Leigh Nation, Jurgen Bullita & John Dallas Boyce
24/04/14
1 Media contribution
Press/Media: Public Engagement Activities