Projects per year
Personal profile
Biography
Professor Boyce is a group leader in the Department of Microbiology, Biomedicine Discovery Institute, Monash University. His research is focused on elucidating the molecular mechanisms of antibiotic resistance, bacterial pathogenesis and host immunity to infections. He works with a wide range of Gram-negative and Gram-positive pathogens including, Acinetobacter baumannii, Pasteurella multocida, Burkholderia pseudomallei, Pseudomonas aeruginosa, Dichelobacter nodosus and Clostridium perfringens. His specialty area of expertise is next generation high-throughput sequencing for bacterial genomics and transcriptomic analyses.
Professor Boyce is a founding member of the Centre to Impact AMR, and is helping to drive our community engagement and environmental engineering strategies.
Research interests
- Acinetobacter baumannii antibiotic resistance mechanisms
- How Acinetobacter baumannii uses its type VI secretion system to kill competitors
- Pasteurella multocida virulence mechanisms
- How small RNAs control gene expression and protein production in Gram-negative bacteria
- Novel antibiotic combinations for improved killing of Gram-negative multi-drug resistant pathogens
Monash teaching commitment
MIC3041
MIC3011
MIC3032
MOL2011
BMS1062
MED1022
MED2042
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- Acinetobacter Baumannii
- Pasteurella Multocida
- Pseudomonas Aeruginosa
- Burkholderia Pseudomallei
- Antibiotic resistance
- Bacteriology
- Bacteriology, vaccines
- Genomics
- Microbiology
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Harnessing type VI secretion system lysins for fighting bacterial superbugs
Boyce, J. (Primary Chief Investigator (PCI)), Harper, M. (Chief Investigator (CI)), Roper, D. (Chief Investigator (CI)), Landersdorfer, C. (Associate Investigator (AI)), Peleg, A. (Associate Investigator (AI)) & Vollmer, W. (Associate Investigator (AI))
1/01/25 → 31/12/27
Project: Research
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Role of Pasteurella surface polysaccharides in pathogenesis and immunity
Boyce, J. (Primary Chief Investigator (PCI)), Harper, M. (Chief Investigator (CI)) & Cox, A. (Partner Investigator (PI))
1/06/21 → 14/10/24
Project: Research
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Virulence Associated small RNAs in Acinetobacter baumannii
Peleg, A. (Primary Chief Investigator (PCI)), Boyce, J. (Chief Investigator (CI)), Vogel, J. (Chief Investigator (CI)) & Short, F. (Chief Investigator (CI))
National Health and Medical Research Council (NHMRC) (Australia)
1/01/21 → 31/12/24
Project: Research
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Combating Pseudomonas aeruginosa infections in paediatric patients with cystic fibrosis
Landersdorfer, C., Deveson, D., Boyce, J., Nation, R. & Oliver, A.
1/01/19 → 31/12/19
Project: Research
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Co-opting bacterial weaponry: Manipulation of the Acinetobacter type VI secretion system for targeted killing of bacteria
Boyce, J., Harper, M. & Drinkwater, N.
1/01/19 → 31/12/22
Project: Research
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Beyond borders: A systematic review and meta-analysis of human-specific faecal markers across geographical settings
Barrett, L. R., Beasy, P., Palacios Delgado, Y. M., Boyce, J. D., Leder, K., McCarthy, D. T. & Henry, R., 2025, In: Critical Reviews in Environmental Science and Technology. 55, 7, p. 447-464 18 p.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access -
Pathogenomic analysis and characterization of Pasteurella multocida strains recovered from human infections
Smallman, T. R., Perlaza-Jiménez, L., Wang, X., Korman, T. M., Kotsanas, D., Gibson, J. S., Turni, C., Harper, M. & Boyce, J. D., Apr 2024, In: Microbiology Spectrum. 12, 4, 16 p., e03805-23.Research output: Contribution to journal › Article › Research › peer-review
Open Access3 Citations (Scopus) -
Structure of a Rhs effector clade domain provides mechanistic insights into type VI secretion system toxin delivery
Hayes, B. K., Harper, M., Venugopal, H., Lewis, J. M., Wright, A., Lee, H.-C., Steele, J. R., Steer, D. L., Schittenhelm, R. B., Boyce, J. D. & McGowan, S., Dec 2024, In: Nature Communications. 15, 1, 15 p., 8709.Research output: Contribution to journal › Article › Research › peer-review
Open Access2 Citations (Scopus) -
Synergistic effects of inhaled aztreonam plus tobramycin on hypermutable cystic fibrosis Pseudomonas aeruginosa isolates in a dynamic biofilm model evaluated by mechanism-based modelling and whole genome sequencing
Breen, S. K. J., Harper, M., López-Causapé, C., Rogers, K. E., Tait, J. R., Smallman, T. R., Lang, Y., Lee, W. L., Zhou, J., Zhang, Y., Bulitta, J. B., Nation, R. L., Oliver, A., Boyce, J. D. & Landersdorfer, C. B., Jun 2024, In: International Journal of Antimicrobial Agents. 63, 6, 107161.Research output: Contribution to journal › Article › Research › peer-review
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Ceftolozane/tazobactam plus tobramycin against free-floating and biofilm bacteria of hypermutable Pseudomonas aeruginosa epidemic strains: Resistance mechanisms and synergistic activity
Agyeman, A. A., López-Causapé, C., Rogers, K. E., Lucas, D. D., Cortés-Lara, S., Gomis-Font, M. A., Fraile-Ribot, P., Figuerola, J., Lang, Y., Franklyn, E. R. T., Lee, W. L., Zhou, J., Zhang, Y., Bulitta, J. B., Boyce, J. D., Nation, R. L., Oliver, A. & Landersdorfer, C. B., Sept 2023, In: International Journal of Antimicrobial Agents. 62, 3, 10 p., 106887.Research output: Contribution to journal › Article › Research › peer-review
9 Citations (Scopus)
Press/Media
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NEW RESISTANCE MECHANISM IN THE OFTEN MULTIDRUG RESISTANT PATHOGEN ACINETOBACTER BAUMANNII
30/04/18
1 Media contribution
Press/Media: Research
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A$9.8 million fight against superbugs
Jian Li, William Neil Charman, Jiangning Song, Anthony Wayne Purcell, Paul John Hertzog, Darren John Creek, Roger Leigh Nation, Jurgen Bullita & John Dallas Boyce
24/04/14
1 Media contribution
Press/Media: Public Engagement Activities