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Personal profile

Biography

A/Prof Boyce is a group leader in the Department of Microbiology, Biomedicine Discovery Institute, Monash University. His research is focused on elucidating the molecular mechanisms of antibiotic resistance, bacterial pathogenesis and host immunity to infections. He works with a wide range of Gram-negative and Gram-positive pathogens including, Acinetobacter baumannii, Pasteurella multocida, Burkholderia pseudomallei, Pseudomonas aeruginosa, Dichelobacter nodosus and Clostridium perfringens. His specialty area of expertise is next generation high-throughput sequencing for bacterial genomics and transcriptomic analyses.

Research interests

  • Acinetobacter baumannii antibiotic resistance mechanisms
  • How Acinetobacter baumannii uses its type VI secretion system to kill competitors
  • Pasteurella multocida virulence mechanisms
  • How small RNAs control gene expression and protein production in Gram-negative bacteria
  • Novel antibiotic combinations for improved killing of Gram-negative multi-drug resistant pathogens

Monash teaching commitment

MIC3041

MIC3011

MIC3032

MOL2011

BMS1062

MED1022

MED2042

Keywords

  • Acinetobacter Baumannii
  • Pasteurella Multocida
  • Pseudomonas Aeruginosa
  • Burkholderia Pseudomallei
  • Antibiotic resistance
  • Bacteriology
  • Bacteriology, vaccines
  • Genomics
  • Microbiology

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Projects 2003 2021

Research Output 2000 2019

Characterization of Hypermutator Pseudomonas aeruginosa Isolates from Patients with Cystic Fibrosis in Australia

Rees, V. E., Deveson Lucas, D. S., López-Causapé, C., Huang, Y., Kotsimbos, T., Bulitta, J. B., Rees, M. C., Barugahare, A., Peleg, A. Y., Nation, R. L., Oliver, A., Boyce, J. D. & Landersdorfer, C. B., 1 Apr 2019, In : Antimicrobial Agents and Chemotherapy. 63, 4, 11 p., e02538-18.

Research output: Contribution to journalArticleResearchpeer-review

Comparable Efficacy and Better Safety of Double -Lactam Combination Therapy versus -Lactam plus Aminoglycoside in Gram-Negative Bacteria in Randomized, Controlled Trials

Jiao, Y., Moya, B., Chen, M. J., Zavascki, A. P., Tsai, H., Tao, X., Sutaria, D. S., Louie, A., Boyce, J. D., Lucas, D. D., Kim, T. H., Tsuji, B. T., Bonomo, R. A., Drusano, G. L. & Bulitta, J. B., Jul 2019, In : Antimicrobial Agents and Chemotherapy. 63, 7, 15 p., e00425-19.

Research output: Contribution to journalArticleResearchpeer-review

Combating Carbapenem-Resistant Acinetobacter baumannii by an Optimized Imipenem-plus-Tobramycin Dosage Regimen: Prospective Validation via Hollow-Fiber Infection and Mathematical Modeling

Landersdorfer, C. B., Yadav, R., Rogers, K. E., Kim, T. H., Shin, B. S., Boyce, J. D., Nation, R. L. & Bulitta, J. B., 1 Apr 2018, In : Antimicrobial Agents and Chemotherapy. 62, 4, 8 p., e02053-17.

Research output: Contribution to journalArticleResearchpeer-review

Determination of the small RNA GcvB regulon in the Gram-negative bacterial pathogen Pasteurella multocida and identification of the GcvB seed binding region

Gulliver, E. L., Wright, A., Deveson, D., Megroz, M., Kleifeld, O., Schittenhelm, R. B., Powell, D. R., Seemann, T., Bulitta, J. B., Harper, M. & Boyce, J. D., 1 May 2018, In : Rna-A Publication of the Rna Society. 24, 5, p. 704-720 17 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Emergence of high-level colistin resistance in an acinetobacter baumannii clinical isolate mediated by inactivation of the global regulator H-NS

Lucas, D. D., Crane, B., Wright, A., Han, M-L., Moffatt, J., Bulach, D., Gladman, S. L., Powell, D., Aranda, J., Seemann, T., Machado, D., Pacheco, T., Marques, T., Viveiros, M., Nation, R., Li, J., Harper, M. & Boyce, J. D., 1 Jul 2018, In : Antimicrobial Agents and Chemotherapy. 62, 7, 17 p., e02442-17.

Research output: Contribution to journalArticleResearchpeer-review

Press / Media