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Personal profile

Biography

I am a Research Fellow with the Institute of Vector-borne Disease. I completed my PhD at the Burnet Institute in Melbourne (2011) in hepatitis C virus, then undertook postdoctoral research in the Department of Biochemistry and Molecular Biology, Monash University. There, I researched the pathogenic roles of the dengue virus NS5 protein and identified several potential antiviral therapeutics, including one that has now been licensed and has patents approved in multiple countries.

 
I joined the Institute of Vector-borne Disease in 2016, and currently run an NHMRC-funded research program focussed on understanding the molecular mechanisms that underpin Wolbachia-mediated virus inhibition in Aedes aegypti mosquitoes - the novel biocontrol tool established by Monash-based World Mosquito program. I am also using molecular virology techniques to determine the risk of viral resistance developing towards this technology. My research primarily uses molecular technologies including high resolution imaging, genomics and proteomics techniques to better understand how Wolbachia modifies this host to create an antiviral environment.

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