Projects per year
Personal profile
Biography
Joel is a proud Palawa man and Proteomics Lead Expert at the Monash University Proteomics & Metabolomics Platform. His expertise in biological mass spectrometry and proteomics has focused on the identification of novel proteins and their post-translational modifications, which are crucial for understanding disease mechanisms and therapeutic targets.
Academic Background:
- PhD in Medical Science (Proteomics) from the University of Technology Sydney, focusing on mass spectrometry analysis of non-protein amino acid misincorporation and proteomic changes in neurotoxicity-related cellular pathways.
- Honours First Class in Medical Science from the University of Technology Sydney, with research on non-protein amino acids' effects on mammalian cells.
- Bachelor of Medical Science from the University of Technology Sydney, specializing in medical, neuroscience, advanced immunology, and molecular biochemistry.
Professional Experience:
- Proteomics Lead at Monash University (Mar 2021 - Present):
Responsible for leading proteomic research, method development, experimental design, and project management. He collaborates with government, academic, and commercial sectors to provide quantitative solutions to biological questions across medical and life sciences. - Analysis Working Group Member at NASA GeneLab (Aug 2022 - Present):
Contributing to maximizing knowledge generation from complex spaceflight-relevant omics datasets. - Fulbright Future Scholar at NASA Ames Research Center (May 2022 - Sep 2022):
Conducted research on bacterial mutation rates due to spaceflight radiation exposure and on mouse muscle proteomes. - Casual Academic at the University of Technology Sydney (May 2016 - Feb 2021):
Taught courses in proteomics, pharmacology, physiological systems, principles of scientific practice, and metabolic biochemistry. - Research Affiliate at the University of Sydney (Feb 2018 - Aug 2019):
Involved in the study of E-Cigarette's effects on the brain in combination with other dietary factors.
Honours and Awards:
- Fulbright Future Scholarship (2021): Awarded for research at NASA’s Jet Propulsion Laboratory, focusing on microbes that can survive extreme conditions.
- NASA-JPL Internship Program (2020): accepted into the summer internship programs at NASA's Jet Propulsion Laboratory.
- Dean's Merit List for Academic Excellence (2017): Recognition for first-class honours at the University of Technology Sydney.
- Poster Prize at Australasian Proteomic Society (2017): For research on proteomic analysis of non-protein amino acids.
Contributions and Collaborations:
Joel has led over 600 proteomic experiments and processed more than 10,000 samples during his four years at Monash. Collaborative efforts span institutions such as the NSW Department of Primary Industries, CSIRO, Australian Defence DSTG, University College London, Stanford University, US-ARMY, Oxford, NASA, and Johns Hopkins University. His research has notably contributed to studies in women's reproductive health and various proteomic analyses related to diseases and space biology.
Research Interests:
Joel's research interests include proteomics, mass spectrometry, analytical biochemistry, and bioinformatics. He is actively involved in developing bioassays, investigating protein misincorporation, and exploring biomarkers for neurodegenerative and infectious diseases.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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SDG 7 Affordable and Clean Energy
Collaborations and top research areas from the last five years
Projects
- 3 Finished
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Validation of a novel immunotherapeutic approach to treat chronic pelvic pain in endometriosis
Castro, J. (Primary Chief Investigator (PCI)), Mehlen, P. (Chief Investigator (CI)), Healey, M. (Chief Investigator (CI)), Steele, J. (Associate Investigator (AI)), Chedotal, A. (Chief Investigator (CI)), Healey, M. (Chief Investigator (CI)), Brierley, S. (Associate Investigator (AI)), Rogers, P. A. W. (Associate Investigator (AI)), Holdsworth-Carson, S. (Associate Investigator (AI)) & Schittenhelm, R. (Associate Investigator (AI))
1/01/24 → 22/10/25
Project: Research
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NHMRC Equipment Grant - PIXUL Multi-Sample Megasonicator (ProtiFi)
Schittenhelm, R. (Primary Chief Investigator (PCI)), Faridi, P. (Chief Investigator (CI)), Creek, D. (Chief Investigator (CI)), Steele, J. (Chief Investigator (CI)), Li, J. (Chief Investigator (CI)), Traven, A. (Chief Investigator (CI)), Lahoud, M. (Chief Investigator (CI)), Daly, R. (Chief Investigator (CI)) & Lim, T. (Chief Investigator (CI))
1/11/23 → 31/12/24
Project: Research
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Establishing a Clinical Single-Cell Proteomics Facility
Schittenhelm, R. (Primary Chief Investigator (PCI)), Nishtala, T. (Chief Investigator (CI)), de Marco, A. (Associate Investigator (AI)), Neild, A. (Associate Investigator (AI)) & Steele, J. (Associate Investigator (AI))
Ian Potter Foundation, Monash University, Bioplatforms Australia Ltd
1/09/23 → 31/08/24
Project: Research
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Mass spectrometry analysis of non-protein amino acid misincorporation and proteomic changes in neurotoxicity-related cellular pathways
Steele, J. R., 14 May 2022, 168 p. Australia : University of Technology, Sydney (UTS).Research output: Other contribution › Research
Open Access -
Misincorporation proteomics technologies: A review
Steele, J. R., Italiano, C. J., Phillips, C. R., Violi, J. P., Pu, L., Rodgers, K. J. & Padula, M. P., Mar 2021, In: Proteomes. 9, 1, 20 p., 2.Research output: Contribution to journal › Article › Research › peer-review
Open Access11 Link opens in a new tab Citations (Scopus) -
Fabry Disease Podocytes Reveal Ferroptosis as a Potential Regulator of Cell Pathology
Wise, A. F., Krisnadevi, I. A., Bruell, S., Lee, H. C., Bhuvan, T., Kassianos, A. J., Saini, S., Wang, X., Healy, H. G., Qian, E. L., Elliot, D. A., Steele, J. R., Fuller, M., Nicholls, K. M. & Ricardo, S. D., Feb 2025, In: Kidney International Reports. 10, 2, p. 535-548 14 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access10 Link opens in a new tab Citations (Scopus) -
Faecal metaproteomics analysis reveals a high cardiovascular risk profile across healthy individuals and heart failure patients
Yang, C., Camargo Tavares, L., Lee, H.-C., Steele, J. R., Ribeiro, R. V., Beale, A. L., Yiallourou, S., Carrington, M. J., Kaye, D. M., Head, G. A., Schittenhelm, R. B. & Marques, F. Z., 2025, In: Gut Microbes. 17, 1, 20 p., 2441356.Research output: Contribution to journal › Article › Research › peer-review
Open Access14 Link opens in a new tab Citations (Scopus) -
Haptoglobin and Glutamine Synthetase May Biomark Cachexia Induced by Antiacute Myeloid Leukaemia Chemotherapy
Campelj, D., Timpani, C., Spiesberger, G., Formosa, L., Steele, J., Zhang, H., Schittenhelm, R., Leow, L., Goodman, C. & Rybalka, E., Jun 2025, In: Journal of Cachexia, Sarcopenia and Muscle. 16, 3, 14 p., e13849.Research output: Contribution to journal › Article › Research › peer-review
Open Access
Activities
- 1 Contribution to conference
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American Society for Gravitational and Space Research Annual Meeting 2022
Steele, J. (Speaker)
10 Nov 2022Activity: Participating in or organising an event types › Contribution to conference