Projects per year
Personal profile
Biography
Professor Joanne Ryan heads the Biological Neuropsychiatry and Dementia research unit in the School of Public Health and Preventive Medicine (SPHPM).
Joanne initially trained as a molecular biologist, completing a University of Melbourne Science degree with honours in the Department of Biochemistry. She then obtained a Masters of Biostatistics through the Biostatistics Collaboration of Australia, at Monash University. She completed in 2011 a PhD in neuropsychiatric epidemiology with the University of Melbourne and Université Montpellier 1, France. Having been awarded an NHMRC Early Career Fellowship in Public Health, she completed an initial post-doc at INSERM (in France) and then returned to Melbourne to develop skills and expertise in epigenetic epidemiology at the Murdoch Children’s Research Institute. In 2017 she was awarded an NHMRC Dementia Research Leadership fellowship, and in 2022 an NHMRC Investigator Grant (Leadership Level 1). She is co-Principal Investigator on the ASPREE-XT study of ageing, and CIA of the STAREE-Mind Clinical Trial substudy, investigating the effects of statins on cognitive ageing and brain health. She co-leads an International Consortium on interventions to promote health aging.
Joanne's research in neuropsychiatric disorders is focused on preventative interventions and risk prediction, and understanding the biological underpinnings of these disorders, as well as biomarker identification (including epigenetics). Her research on healthy aging is focused on identifying interventions which can prolong the period of life spent in good health, and the interplay between healthspan and biological aging. Her long-term vision is to reduce the prevalence and burden of neuropsychiatric disorders across the life-course, and identify strategies to optimise cognitive and physical health with aging.
Research interests
Dementia; Cognitive Aging; Frailty; Intrinsic Capacity; Healthspan; Epigenetics; Biological Aging; Stress/Trauma
https://www.monash.edu/medicine/sphpm/units/biological-neuropsychiatry-and-dementia
Monash teaching commitment
Honours Coordinator, Bachelor of Biomedical Science, SPHPM
BMS4200 - Biostatistics for Honours Students (Unit Coordinator)
BMS3052 - Biomedical Basis & Epidemiology of Human Disease
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
External positions
Honorary Research Fellow, Murdoch Children's Research Institute
Jul 2017 → …
Honorary Research Fellow, University of Melbourne
Apr 2013 → …
Honorary Research Fellow, INSERM - Institut National de la Sante et de la Recherche Medicale (National Institute of Health and Medical Research)
Jan 2011 → …
Research area keywords
- Dementia
- Alzheimer's Disease
- Frailty
- Epigenetics
- Epidemiology
- Biostatistics
- Aging/Gerontology
- Stress
- Psychiatric Disorders
- Trauma
- Life Course
Collaborations and top research areas from the last five years
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Building knowledge to better target stress-reducing interventions and delay the onset of Alzheimer’s Disease.
Ryan, J., McNeil, J., Woods, R. & Ancelin, M.
1/02/17 → 31/01/18
Project: Research
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Drivers of ageing and adaptive ageing in middle-aged and older adults.
Olsson, C., Slade, T. N., Ryan, J., Butterworth, P., Wuthrich, V. M., Hancox, R. J., Robinson, S., Letcher, P., Greenwood, C. J. & Enticott, P.
1/01/24 → 31/12/26
Project: Research
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The effect of an adverse psychological environment on salivary cortisol levels in the elderly differs by 5-HTTLPR genotype
Ancelin, M. L., Scali, J., Norton, J., Ritchie, K., Dupuy, A. M., Chaudieu, I. & Ryan, J., 1 Dec 2017, In: Neurobiology of Stress. 7, p. 38-46 9 p.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile11 Citations (Scopus) -
Does maternal mental well-being in pregnancy impact the early human epigenome?
Ryan, J., Mansell, T., Fransquet, P. & Saffery, R., 1 Mar 2017, In: Epigenomics. 9, 3, p. 313-322 10 p.Research output: Contribution to journal › Review Article › Research › peer-review
35 Citations (Scopus) -
Biological underpinnings of trauma and post-traumatic stress disorder: Focusing on genetics and epigenetics
Ryan, J., Chaudieu, I., Ancelin, M-L. & Saffery, R., 1 Nov 2016, In: Epigenomics. 8, 11, p. 1553-1569 17 p.Research output: Contribution to journal › Review Article › Research › peer-review
Open AccessFile56 Citations (Scopus) -
BDNF promoter methylation and genetic variation in late-life depression
Januar, V., Ancelin, M. L., Ritchie, K., Saffery, R. & Ryan, J., 25 Aug 2015, In: Translational Psychiatry. 5, 8, 7 p., e619.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile111 Citations (Scopus) -
Epigenetics and depressive disorders: A review of current progress and future directions
Januar, V., Saffery, R. & Ryan, J., 1 Aug 2015, In: International Journal of Epidemiology. 44, 4, p. 1364-1387 24 p.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile80 Citations (Scopus)
Prizes
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Scientific Mobility Travel Grant
Ryan, Joanne (Recipient), 2013
Prize: Prize (including medals and awards)
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Society for Mental Health Research (SMHR) Conference, Best Poster
Ryan, Joanne (Recipient), 2014
Prize: Prize (including medals and awards)
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Yulgibar Foundation Post-doctoral Excellence Award
Ryan, Joanne (Recipient), 2016
Prize: Prize (including medals and awards)
Activities
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NHMRC Grant Review Panel: Spokesperson (Event)
Joanne Ryan (Member)
21 Aug 2017 → 25 Aug 2017Activity: External Academic Engagement › Peer review panel or committee
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Section Editor (Event)
Joanne Ryan (Editor in chief)
2016 → …Activity: Publication peer-review and editorial work types › Editorial responsibility
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Victoria State Government (External organisation)
Joanne Ryan (Member)
13 Apr 2021 → 12 Apr 2024Activity: Industry, Government and Philanthropy Engagement and Partnerships › Membership of an advisory panel/policy group/ board
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NHMRC GRP
Joanne Ryan (Fellow)
Aug 2018Activity: External Academic Engagement › Peer review panel or committee
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Life Science Research
Joanne Ryan (Reviewer)
2017Activity: External Academic Engagement › Grant review responsibilities
Press/Media
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The faster your epigenetic clock ticks, the higher the chance your health is in decline
17/12/24
1 Media contribution
Press/Media: Article/Feature
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Lifestyle Enrichment in Later Life and Its Association With Dementia Risk
17/07/23 → 15/08/23
5 Media contributions
Press/Media: Research
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The activities most likely to help ward off dementia
17/07/23
1 Media contribution
Press/Media: Article/Feature
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Congratulations to all of our successful NHMRC Investigator Grant recipients!
12/10/22
1 Media contribution
Press/Media: Profile/Interview