Jo-Anne Pinson

Dr

20102016
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Research Output 2010 2016

Development of single and mixed isoform selectivity PI3Kδ inhibitors by targeting Asn836 of PI3Kδ

Miller, M. S., Mountford, S. J., Pinson, J-A., Zheng, Z., Künzli, M., Patel, V., Hogg, S. J., Shortt, J., Jennings, I. G. & Thompson, P. E., 1 Oct 2016, In : Bioorganic and Medicinal Chemistry Letters. 26, 19, p. 4790-4794 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Discovery and antiplatelet activity of a selective PI3Kβ inhibitor (MIPS-9922)

Zheng, Z., Pinson, J. A., Mountford, S. J., Orive, S., Schoenwaelder, S. M., Shackleford, D., Powell, A., Nelson, E. M., Hamilton, J. R., Jackson, S., Jennings, I. G. & Thompson, P. E., 21 Oct 2016, In : European Journal of Medicinal Chemistry. 122, p. 339-351 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Evidence for the in vitro bioactivation of aminopyrazole derivatives: trapping reactive aminopyrazole intermediates using glutathione ethyl ester in human liver microsomes

Ryan, E., Morrow, B. J., Hemley, C. F., Pinson, J-A., Charman, S. A., Chiu, F. C. K. & Foitzik, R. C., 2015, In : Chemical Research in Toxicology. 28, 9, p. 1747-1752 6 p.

Research output: Contribution to journalArticleResearchpeer-review

L-aminoacyl-triazine derivatives are isoform-selective PI3KB inhibitors that target nonconserved Asp862 of PI3KB

Pinson, J-A., Zheng, Z., Miller, M. S., Chalmers, D. K., Jennings, I. & Thompson, P., 2013, In : A C S Medicinal Chemistry Letters. 4, 2, p. 206 - 210 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Regioselective synthesis of 5- and 6-methoxybenzimidazole-1,3,5-triazines as inhibitors of phosphoinositide 3-kinase

Miller, M. S., Pinson, J-A., Zheng, Z., Jennings, I. & Thompson, P., 2013, In : Bioorganic and Medicinal Chemistry Letters. 23, 3, p. 802 - 805 4 p.

Research output: Contribution to journalArticleResearchpeer-review