Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 2 Active
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Pre-clinical evaluation of selective adenosine A1 receptor positive allosteric modulators for the treatment of drug-resistant epilepsy
Kwan, P. (Primary Chief Investigator (PCI)), May, L. (Chief Investigator (CI)), Rollo, B. (Chief Investigator (CI)), O'Brien, T. (Chief Investigator (CI)), Casillas-Espinosa, P. (Chief Investigator (CI)), Howden, S. (Chief Investigator (CI)), Christopoulos, A. (Chief Investigator (CI)), Gregory, K. (Chief Investigator (CI)), Scammells, P. (Chief Investigator (CI)), Baltos, J.-A. (Chief Investigator (CI)), Elliot, D. (Chief Investigator (CI)), TN Nguyen, A. (Chief Investigator (CI)), Langmead, C. (Chief Investigator (CI)), Antonic-Baker, A. (Chief Investigator (CI)), Sumer, H. (Chief Investigator (CI)), Javaid, S. (Associate Investigator (AI)) & Gu, J. (Chief Investigator (CI))
1/06/22 → 31/05/27
Project: Research
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Positive allosteric modulation of anti-convulsant G protein-coupled receptor signalling to treat drug-resistant epilepsy
May, L. (Primary Chief Investigator (PCI)), Webb, G. (Chief Investigator (CI)), Carlsson, J. (Chief Investigator (CI)), Baltos, J.-A. (Chief Investigator (CI)), TN Nguyen, A. (Chief Investigator (CI)), Christopoulos, A. (Associate Investigator (AI)), Miao, Y. (Associate Investigator (AI)), O'Brien, T. (Associate Investigator (AI)), Rollo, B. (Associate Investigator (AI)), Casillas-Espinosa, P. (Associate Investigator (AI)), Gregory, K. (Associate Investigator (AI)), Scammells, P. (Associate Investigator (AI)) & Nguyen, T. (Associate Investigator (AI))
1/01/22 → 31/12/25
Project: Research
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Development of Putative Bivalent Dicovalent Ligands for the Adenosine A1 Receptor
Payne, C. M., Baltos, J. A., Langiu, M., Sinh Lu, C., Tyndall, J. D. A., Gregory, K. J., May, L. T. & Vernall, A. J., 1 Oct 2024, In: ChemBioChem. 25, 19, 10 p., e202400242.Research output: Contribution to journal › Article › Research › peer-review
Open Access2 Citations (Scopus) -
The role of the adenosine system in epilepsy and its comorbidities
Baltos, J. A., Casillas-Espinosa, P. M., Rollo, B., Gregory, K. J., White, P. J., Christopoulos, A., Kwan, P., O'Brien, T. J. & May, L. T., Jul 2024, In: British Journal of Pharmacology. 181, 14, p. 2143-2157 15 p.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access16 Citations (Scopus) -
Small molecule allosteric modulation of the adenosine A1 receptor
Nguyen, A. T. N., Tran, Q. L., Baltos, J. A., McNeill, S. M., Nguyen, D. T. N. & May, L. T., 26 Jun 2023, In: Frontiers in Endocrinology. 14, 12 p., 1184360.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access7 Citations (Scopus) -
Structure-based virtual screening discovers potent and selective adenosine A1 receptor antagonists
Matricon, P., Nguyen, A. T., Vo, D. D., Baltos, J. A., Jaiteh, M., Luttens, A., Kampen, S., Christopoulos, A., Kihlberg, J., May, L. T. & Carlsson, J., 5 Sept 2023, In: European Journal of Medicinal Chemistry. 257, 115419.Research output: Contribution to journal › Article › Research › peer-review
Open Access7 Citations (Scopus) -
Adenosine receptor signalling in Alzheimer’s disease
Trinh, P. N. H., Baltos, J. A., Hellyer, S. D., May, L. T. & Gregory, K. J., Jul 2022, In: Purinergic Signalling. 18, p. 359–381 23 p.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access20 Citations (Scopus)