Projects per year
Personal profile
Biography
Dr Jinchao Gu is a postdoctoral research fellow in the Department of Neuroscience, School of Translational Medicine, Monash University. He completed his PhD at Swinburne University of Technology in February 2023 and commenced his postdoc position at Monash in January 2023.
In the Stem Cell laboratory, his research focuses on generating in vitro neuronal cell models derived from human pluripotent stem cells (hiPSCs) for studying neurological disorders such as epilepsy. He has developed expertise in molecular cloning, rapid neural differentiation from hiPSCs and CRISPR/Cas9 genome editing, which allows disease modelling of specific genetic mutations and screening of potential anti-seizure drugs.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Biotechnology, PhD, Investigation of GABAA receptors in differentiated neurons in vitro, Swinburne University of Technology
8 Mar 2018 → 9 Feb 2023
Award Date: 9 Feb 2023
Research area keywords
- Stem Cell
- Neuroscience
- CRISPR Cas9
- Genome Editing
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 2 Active
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Precision gene silencing of Homer1R297W transcripts by antisense oligonucleotides in induced pluripotent stem cell-derived neural models
Rollo, B. (Primary Chief Investigator (PCI)), Gu, J. (Chief Investigator (CI)) & Ayers, K. (Chief Investigator (CI))
16/07/25 → 9/01/27
Project: Research
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Pre-clinical evaluation of selective adenosine A1 receptor positive allosteric modulators for the treatment of drug-resistant epilepsy
Kwan, P. (Primary Chief Investigator (PCI)), May, L. (Chief Investigator (CI)), Rollo, B. (Chief Investigator (CI)), O'Brien, T. (Chief Investigator (CI)), Casillas-Espinosa, P. (Chief Investigator (CI)), Howden, S. (Chief Investigator (CI)), Christopoulos, A. (Chief Investigator (CI)), Gregory, K. (Chief Investigator (CI)), Scammells, P. (Chief Investigator (CI)), Baltos, J.-A. (Chief Investigator (CI)), Elliott, D. (Chief Investigator (CI)), TN Nguyen, A. (Chief Investigator (CI)), Langmead, C. (Chief Investigator (CI)), Antonic-Baker, A. (Chief Investigator (CI)), Sumer, H. (Chief Investigator (CI)), Javaid, S. (Associate Investigator (AI)) & Gu, J. (Chief Investigator (CI))
1/06/22 → 31/05/27
Project: Research
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Electrical stimulation of stem cell–derived human neural networks for evaluating anti-seizure medications
Nicholls, J. (Leading Author), Gu, J., Chen, Z., Liu, Z., Antonic-Baker, A., Javaid, M. S., Moore, E., Zhu, H., Altalhi, A., Wright, D. K., Sumer, H., O'Brien, T. J., Kwan, P. (Leading Author) & Rollo, B. (Leading Author), 2025, (Accepted/In press) In: Epilepsia. 19 p., 19.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Ngn2-Induced Differentiation of the NG108-15 Cell Line Enhances Motor Neuronal Differentiation and Neuromuscular Junction Formation
Meli, M., Swiderski, K., Gu, J., Rollo, B., Bartlett, B., Caldow, M. K., Lynch, G. S., Kwan, P., Sumer, H. & Cromer, B., May 2025, In: Biomolecules. 15, 5, 24 p., 637.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Generation of a stably transfected mouse embryonic stem cell line for inducible differentiation to excitatory neurons
Gu, J., Rollo, B., Geza, B., Petrou, S., Kwan, P., Sumer, H. & Cromer, B., 1 Feb 2024, In: Experimental Cell Research. 435, 1, 8 p., 113902.Research output: Contribution to journal › Article › Research › peer-review
3 Citations (Scopus) -
TRAPPopathies: Severe Multisystem Disorders Caused by Variants in Genes of the Transport Protein Particle (TRAPP) Complexes
Hall, R., Sawant, V., Gu, J., Sikora, T., Rollo, B., Velasco, S., Kim, J., Segev, N., Christodoulou, J. & Van Bergen, N. J., Dec 2024, In: International Journal of Molecular Sciences. 25, 24, 22 p., 13329.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access1 Citation (Scopus) -
Efficient Generation of Stable Cell Lines with Inducible Neuronal Transgene Expression Using the piggyBac Transposon System
Gu, J., Sumer, H. & Cromer, B., 2022, Applications of Genome Modulation and Editing. Verma, P. J., Sumer, H. & Liu, J. (eds.). USA: Humana Press, p. 49-66 18 p. (Methods in Molecular Biology; vol. 2495).Research output: Chapter in Book/Report/Conference proceeding › Chapter (Book) › Other › peer-review
3 Citations (Scopus)