Projects per year
Personal profile
Biography
Dr Jinchao Gu is a postdoctoral research fellow in the Department of Neuroscience, School of Translational Medicine, Monash University. He completed his PhD at Swinburne University of Technology in February 2023 and commenced his postdoc position at Monash in January 2023.
In the Stem Cell laboratory, his research focuses on generating in vitro neuronal cell models derived from human pluripotent stem cells (hiPSCs) for studying neurological disorders such as epilepsy. He has developed expertise in molecular cloning, rapid neural differentiation from hiPSCs and CRISPR/Cas9 genome editing, which allows disease modelling of specific genetic mutations and screening of potential anti-seizure drugs.
Education/Academic qualification
Biotechnology, PhD, Investigation of GABAA receptors in differentiated neurons in vitro, Swinburne University of Technology
8 Mar 2018 → 9 Feb 2023
Award Date: 9 Feb 2023
Research area keywords
- Stem Cell
- Neuroscience
- CRISPR Cas9
- Genome Editing
Collaborations and top research areas from the last five years
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Projects
- 1 Active
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Pre-clinical evaluation of selective adenosine A1 receptor positive allosteric modulators for the treatment of drug-resistant epilepsy
Kwan, P., May, L., Rollo, B., O'Brien, T., Casillas-Espinosa, P., Howden, S., Christopoulos, A., Gregory, K., Scammells, P., Baltos, J., Elliot, D., TN Nguyen, A., Langmead, C., Antonic-Baker, A., Sumer, H., Javaid, S. & Gu, J.
1/06/22 → 31/05/27
Project: Research
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Generation of a stably transfected mouse embryonic stem cell line for inducible differentiation to excitatory neurons
Gu, J., Rollo, B., Geza, B., Petrou, S., Kwan, P., Sumer, H. & Cromer, B., 1 Feb 2024, In: Experimental Cell Research. 435, 1, 8 p., 113902.Research output: Contribution to journal › Article › Research › peer-review
2 Citations (Scopus) -
Efficient Generation of Stable Cell Lines with Inducible Neuronal Transgene Expression Using the piggyBac Transposon System
Gu, J., Sumer, H. & Cromer, B., 2022, Applications of Genome Modulation and Editing. Verma, P. J., Sumer, H. & Liu, J. (eds.). USA: Humana Press, p. 49-66 18 p. (Methods in Molecular Biology; vol. 2495).Research output: Chapter in Book/Report/Conference proceeding › Chapter (Book) › Other › peer-review
3 Citations (Scopus) -
Targeting the AAVS1 Site by CRISPR/Cas9 with an Inducible Transgene Cassette for the Neuronal Differentiation of Human Pluripotent Stem Cells
Gu, J., Rollo, B., Sumer, H. & Cromer, B., 2022, Applications of Genome Modulation and Editing. Verma, P. J., Sumer, H. & Liu, J. (eds.). New York USA: Humana Press, p. 99-114 16 p. (Methods in Molecular Biology; vol. 2495).Research output: Chapter in Book/Report/Conference proceeding › Chapter (Book) › Other › peer-review
3 Citations (Scopus) -
Forward programming of pluripotent stem cells to neurons
Gu, J., Cromer, B. & Sumer, H., 27 Jan 2021, In: Current Molecular Medicine. 21, 1, p. 5-14 10 p.Research output: Contribution to journal › Review Article › Research › peer-review
1 Citation (Scopus)