Projects per year
Personal profile
Biography
Dr Jie Tang is an NHMRC Emerging Leadership Fellow, who has expertise in biomedical engineering, pharmaceutics and nanotechnology. Her research endeavors encompass both fundamental and applied research at the nano-bio interface through nanomaterial innovation. Specifically, Dr Tang's group is dedicated to develop nanoparticle-based platforms tailored for drug and gene delivery, cancer immunotherapy and vaccine adjuvants, leveraging the nanoparticles' unique nanostructure and surface chemistry.
Since completing her PhD at UQ in 2018, Dr Tang has secured research grants as CI totalling over AU$ 2.3 million and etabilished licensing aggreements with industry partners like AstraZeneca.
Joining D4, MIPS in fall 2023, Dr Tang aims to collaborate with fellow researchers to explore the interaction between nanoparticles and biological barriers, optimizing their efficacy for therapeutic and vaccine purposes.
Research interests
- Engineering biomimetic nanoplatform for oral delivery of large biomolecules (ie, mRNA/pDNA/siRNA/protein);
- Nanoparticle-based vaccine adjuvants (Nanoadjuvants);
- Nanomaterials-based cancer immunotherapy;
- Orally delivered nanovaccines for preventing cancer relapse.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- Drug Delivery Systems
- Oral delivery
- Cancer immunotherapy
- Adjuvants
- Nanoparticles
- Gene delivery
- Vaccines
Collaborations and top research areas from the last five years
Projects
- 4 Active
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Innovative Oral Vaccines for Memory T Cell-Based Cancer Relapse Prevention
Tang, J. & Hollande, F.
1/03/25 → 1/03/27
Project: Research
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Hierarchical nanostructure effects on Nanoparticle-M Cell Interactions
Tang, J., McIntosh, M. & Boyd, B.
3/02/25 → 2/02/28
Project: Research
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Bio-inspired Nanoparticles for Mechano-Regulation of Stem Cell Fate
Qiao, R., Ju, L., Ngo, S. T. & Tang, J.
18/06/24 → 17/06/27
Project: Research
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Fighting Cancer Relapse: Developing an Oral Cancer Vaccine Generating Memory T Cells
2/10/23 → 31/01/28
Project: Research
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Lipase-powered asymmetric silica nanomotors with a tailored head-tail structure for enhanced mucus penetration
Ban, W., Qu, J., Cai, L., Fu, J., Wu, W., Song, H., Yu, C. & Tang, J., Oct 2023, In: Applied Materials Today. 34, 8 p., 101916.Research output: Contribution to journal › Article › Research › peer-review
Open Access6 Citations (Scopus) -
Surface chemistry of spiky silica nanoparticles tailors polyethyleneimine binding and intracellular DNA delivery
Cheng, D., Theivendran, S., Tang, J., Cai, L., Zhang, J., Song, H. & Yu, C., 15 Dec 2022, In: Journal of Colloid and Interface Science. 628, Part B, p. 297-305 9 p.Research output: Contribution to journal › Article › Research › peer-review
11 Citations (Scopus) -
Mesoporous sodium four-coordinate aluminosilicate nanoparticles modulate dendritic cell pyroptosis and activate innate and adaptive immunity
Tang, J., Yang, Y., Qu, J., Ban, W., Song, H., Gu, Z., Yang, Y., Cai, L., Theivendran, S., Wang, Y., Zhang, M. & Yu, C., 20 Jul 2022, In: Chemical Science. 13, 29, p. 8507-8517 11 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access16 Citations (Scopus) -
A Sub-6 nm MnFe2O4-dichloroacetic acid nanocomposite modulates tumor metabolism and catabolism for reversing tumor immunosuppressive microenvironment and boosting immunotherapy
Dai, Z., Wang, Q., Tang, J., Qu, R., Wu, M., Li, H., Yang, Y., Zhen, X. & Yu, C., May 2022, In: Biomaterials. 284, 11 p., 121533.Research output: Contribution to journal › Article › Research › peer-review
29 Citations (Scopus) -
Immune-regulating bimetallic metal-organic framework nanoparticles designed for cancer immunotherapy
Dai, Z., Wang, Q., Tang, J., Wu, M., Li, H., Yang, Y., Zhen, X. & Yu, C., Jan 2022, In: Biomaterials. 280, 13 p., 121261.Research output: Contribution to journal › Article › Research › peer-review
44 Citations (Scopus)
Prizes
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Advance Queensland Industry Research Fellowship
Tang, Jie (Recipient), 2020
Prize: Competitive Fellowships
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Best Poster Prize at the RSC Materials Chemistry Division Poster Symposium
Tang, Jie (Recipient), 2016
Prize: Prize (including medals and awards)
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First prize in 2020 AIBN Image Contest
Tang, Jie (Recipient), 2020
Prize: Prize (including medals and awards)
-
International Association of Advanced Materials (IAAM) Young Scientist Medal
Tang, Jie (Recipient), 2021
Prize: Prize (including medals and awards)
-
NHMRC Investigator Grants Emerging Leadership
Tang, Jie (Recipient), 2022
Prize: Competitive Fellowships