Accepting PhD Students

PhD projects

1. Engineering biomimetic nanoplatform for oral delivery: Developing novel biomimetic drug delivery platform based on nanoparticles with engineered morphology/architecture, mimicking gut microbes to achieve enhanced mucus penetration and transcytosis through intestinal epithelium for enhanced delivery of large biomolecules, i.e., pDNA, mRNA and protein.

2. Nanoparticle-based vaccine adjuvant for cancer prevention: By combining state-of-the-art nanotechnology and classical coordination chemistry, we are developing new generation nanoadjuvants with improved efficacy and safety over current market Alum-based adjuvants.

3. Nanoparticle-based oral vaccine for infection control.

20112024

Research activity per year

Personal profile

Biography

Dr Jie Tang is an NHMRC Emerging Leadership Fellow, who has expertise in biomedical engineering, pharmaceutics and nanotechnology. Her research endeavors encompass both fundamental and applied research at the nano-bio interface through nanomaterial innovation. Specifically, Dr Tang's group is dedicated to develop nanoparticle-based platforms tailored for drug and gene delivery, cancer immunotherapy and vaccine adjuvants, leveraging the nanoparticles' unique nanostructure and surface chemistry. Dr Tang has achieved >46 research outputs, including 3 patents, with >1800 citations, an H-index of 23 (Google Scholar, as of November 2023).

Since completing her PhD at UQ in 2018, Dr Tang has secured research grants as CI totalling over AU$ 1.5 million and etabilished licensing aggreements with industry partners like AstraZeneca.

Joining D4, MIPS in fall 2023, Dr Tang aims to collaborate with fellow researchers to explore the interaction between nanoparticles and biological barriers, optimizing their efficacy for therapeutic and vaccine purposes.

Research interests

  • Engineering biomimetic nanoplatform for oral delivery of large biomolecules (ie, mRNA/pDNA/siRNA/protein);
  • Nanoparticle-based vaccine adjuvants (Nanoadjuvants);
  • Nanomaterials-based cancer immunotherapy;
  • Orally delivered nanovaccines for preventing cancer relapse.

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Research area keywords

  • Drug Delivery Systems
  • Oral delivery
  • Cancer immunotherapy
  • Adjuvants
  • Nanoparticles
  • Gene delivery
  • Vaccines

Collaborations and top research areas from the last five years

Recent external collaboration on country/territory level. Dive into details by clicking on the dots or