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Personal profile

Biography

Professor Jian Li (PhD 2002) is Head of the Antimicrobial Systems Pharmacology Laboratory at the Biomedicine Discovery Institute, Monash University. He is a Web of Science 2015 - 2017 Highly Cited Researcher in Pharmacology & Toxicology. Dr Li has an internationally recognised track record in the pharmacology of polymyxins and the discovery of novel, safer polymyxins. He has 285 publications (including 225 on polymyxins alone) with 12,500 citations and an h-index of 55. Dr Li is an Editor of the International Journal of Antimicrobial Agents and an Associate Editor of BMC Microbiology. He is an invited reviewer for 152 international journals and grant/fellowship applications for 14 international funding bodies. His research is funded by NIH, Australian National Health and Medical Research Council (NHMRC), Australian Research Council (ARC), pharmaceutical companies and other grant bodies. Dr Li has received numerous awards, including Australian Leadership Award (2013), Australian National Health and Medical Research Council’s Ten of the Best Research Projects (2014) and Australian Academy of Science Jacques Miller Medal (2017).

Monash teaching commitment

Supervisor of PhD, Masters and Honours students

Keywords

  • Antimicrobial Resistance
  • Drug Discovery
  • Antimicrobial Pharmacology
  • Systems Pharmacology
  • Computational Biology
  • Bioinformatics
  • Polymyxin
  • Colistin
  • Pharmacodynamics
  • Pharmacokinetics
  • Acinetobacter baumannii
  • Klebsiella pneumoniae
  • Pseudomonas aeruginosa

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Projects 2004 2023

Research Output 2001 2019

Comparative metabolomics and transcriptomics reveal multiple pathways associated with polymyxin killing in pseudomonas aeruginosa

Han, M-L., Zhu, Y., Creek, D. J., Lin, Y-W., Gutu, A. D., Hertzog, P., Purcell, T., Shen, H-H., Moskowitz, S. M., Velkov, T. & Li, J., 1 Jan 2019, In : mSystems. 4, 1, 18 p., e00149-18.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Contemporary Anti-Ebola Drug Discovery Approaches and Platforms

Schneider-Futschik, E. K., Hoyer, D., Khromykh, A. A., Baell, J. B., Marsh, G. A., Baker, M. A., Li, J. & Velkov, T., 1 Nov 2019, In : ACS Infectious Diseases. 5, 1, p. 35-48 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Effects of the antibiotic component on in-vitro bacterial killing, physico-chemical properties, aerosolization and dissolution of a ternary-combinational inhalation powder formulation of antibiotics for pan-drug resistant Gram-negative lung infections

Mangal, S., Huang, J., Shetty, N., Park, H., Lin, Y., Yu, H. H., Zemlyanov, D., Velkov, T., Li, J. & Zhou, Q. T., 20 Apr 2019, In : International Journal of Pharmaceutics. 561, p. 102-113 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Novel polymyxin combination with the antiretroviral zidovudine exerts synergistic killing against Ndm-producing multidrug-resistant klebsiella pneumoniae

Lin, Y-W., Rahim, N. A., Zhao, J., Han, M-L., Yu, H. H., Wickremasinghe, H., Chen, K., Wang, J., Paterson, D. L., Zhu, Y., Rao, G. G., Zhou, Q. T., Forrest, A., Velkov, T. & Li, J., 1 Apr 2019, In : Antimicrobial Agents and Chemotherapy. 63, 4, 11 p., e02176-18.

Research output: Contribution to journalArticleResearchpeer-review

Understanding the Impacts of Surface Compositions on the In-Vitro Dissolution and Aerosolization of Co-Spray-Dried Composite Powder Formulations for Inhalation

Mangal, S., Xu, R., Park, H., Zemlyanov, D., Shetty, N., Lin, Y-W., Morton, D., Chan, H-K., Li, J. & Zhou, T. Q., 1 Jan 2019, In : Pharmaceutical Research. 36, 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Activities 2011 2011

  • 1 Submissions to industry or govt committees, commissions and inquiries

Drug Delivery, Disposition and Dynamics

Jian Li (Member)
9 Nov 20119 Sep 2099

Activity: External Academic EngagementSubmissions to industry or govt committees, commissions and inquiries

Press / Media

AI tool to boost genomic data analysis

Jiangning Song, Roger Daly & Jian Li

25/04/19

1 media contribution

Press/Media: Research

Genome scale model of a superbug

Trevor Lithgow, Jian Li & Jiangning Song

16/03/1830/03/18

2 media contributions

Press/Media: Research

A$9.8 million fight against superbugs

Jian Li, William Charman, Jiangning Song, Anthony Purcell, Paul Hertzog, Darren Creek, Roger Nation, Jurgen Bullita & John Boyce

24/04/14

1 media contribution

Press/Media: Public Engagement Activities