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Personal profile


Professor Jian Li (PhD 2002) is Head of the Antimicrobial Systems Pharmacology Laboratory at the Biomedicine Discovery Institute, Monash University. He is a Web of Science 2015 - 2017 Highly Cited Researcher in Pharmacology & Toxicology. Dr Li has an internationally recognised track record in the pharmacology of polymyxins and the discovery of novel, safer polymyxins. He has 317 publications (including 252 on polymyxins alone) with 15,109 citations and an h-index of 60. Dr Li is an Editor of the International Journal of Antimicrobial Agents and an Associate Editor of BMC Microbiology and Frontiers in Microbiology. He is an invited reviewer for 167 international journals and grant/fellowship applications for 18 international funding bodies. His research is funded by NIH, Australian National Health and Medical Research Council (NHMRC), Australian Research Council (ARC), pharmaceutical companies and other grant bodies. Dr Li has received numerous awards, including Australian Leadership Award (2013), Australian National Health and Medical Research Council’s Ten of the Best Research Projects (2014) and Australian Academy of Science Jacques Miller Medal (2017).

Monash teaching commitment

Supervisor of PhD, Masters and Honours students

Research area keywords

  • Antimicrobial Resistance
  • Drug Discovery
  • Antimicrobial Pharmacology
  • Systems Pharmacology
  • Computational Biology
  • Bioinformatics
  • Polymyxin
  • Colistin
  • Pharmacodynamics
  • Pharmacokinetics
  • Acinetobacter baumannii
  • Klebsiella pneumoniae
  • Pseudomonas aeruginosa

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Projects 2004 2023

Research Output 2001 2019

A comprehensive review and performance evaluation of bioinformatics tools for HLA class I peptide-binding prediction

Mei, S., Li, F., Leier, A., Marquez-Lago, T. T., Giam, K., Croft, N. P., Akutsu, T., Smith, A. I., Li, J., Rossjohn, J., Purcell, A. W. & Song, J., 14 Jun 2019, (Accepted/In press) In : Briefings in Bioinformatics. 17 p., bbz051.

Research output: Contribution to journalReview ArticleResearchpeer-review

4 Citations (Scopus)

Comparative metabolomics and transcriptomics reveal multiple pathways associated with polymyxin killing in pseudomonas aeruginosa

Han, M-L., Zhu, Y., Creek, D. J., Lin, Y-W., Gutu, A. D., Hertzog, P., Purcell, T., Shen, H-H., Moskowitz, S. M., Velkov, T. & Li, J., 1 Jan 2019, In : mSystems. 4, 1, 18 p., e00149-18.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Comparative metabolomics reveals key pathways associated with the synergistic killing of colistin and sulbactam combination against multidrug-resistant Acinetobacter baumannii

Han, M-L., Liu, X., Velkov, T., Lin, Y-W., Zhu, Y., Creek, D. J., Barlow, C. K., Yu, H. H., Zhou, Z., Zhang, J. & Li, J., 4 Jul 2019, In : Frontiers in Pharmacology. 10, 11 p., 754.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Contemporary Anti-Ebola Drug Discovery Approaches and Platforms

Schneider-Futschik, E. K., Hoyer, D., Khromykh, A. A., Baell, J. B., Marsh, G. A., Baker, M. A., Li, J. & Velkov, T., 1 Nov 2019, In : ACS Infectious Diseases. 5, 1, p. 35-48 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Effects of the antibiotic component on in-vitro bacterial killing, physico-chemical properties, aerosolization and dissolution of a ternary-combinational inhalation powder formulation of antibiotics for pan-drug resistant Gram-negative lung infections

Mangal, S., Huang, J., Shetty, N., Park, H., Lin, Y., Yu, H. H., Zemlyanov, D., Velkov, T., Li, J. & Zhou, Q. T., 20 Apr 2019, In : International Journal of Pharmaceutics. 561, p. 102-113 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Activities 2011 2011

  • 1 Submissions to industry or govt committees, commissions and inquiries

Drug Delivery, Disposition and Dynamics

Jian Li (Member)
9 Nov 20119 Sep 2099

Activity: External Academic EngagementSubmissions to industry or govt committees, commissions and inquiries

Press / Media

AI tool to boost genomic data analysis

Jiangning Song, Roger Daly & Jian Li


1 Media contribution

Press/Media: Research

Genome scale model of a superbug

Trevor Lithgow, Jian Li & Jiangning Song


2 Media contributions

Press/Media: Research