Projects per year
Personal profile
Biography
Professor Jian Li (PhD 2002) is Head of the Antimicrobial Systems Pharmacology Laboratory at the Biomedicine Discovery Institute, Monash University. He is a Web of Science 2015 - 2017 Highly Cited Researcher in Pharmacology & Toxicology. Dr Li has an internationally recognised track record in the pharmacology of polymyxins and the discovery of novel, safer polymyxins. He has 285 publications (including 225 on polymyxins alone) with 12,500 citations and an h-index of 55. Dr Li is an Editor of the International Journal of Antimicrobial Agents and an Associate Editor of BMC Microbiology. He is an invited reviewer for 152 international journals and grant/fellowship applications for 14 international funding bodies. His research is funded by NIH, Australian National Health and Medical Research Council (NHMRC), Australian Research Council (ARC), pharmaceutical companies and other grant bodies. Dr Li has received numerous awards, including Australian Leadership Award (2013), Australian National Health and Medical Research Council’s Ten of the Best Research Projects (2014) and Australian Academy of Science Jacques Miller Medal (2017).
Monash teaching commitment
Supervisor of PhD, Masters and Honours students
Keywords
- Antimicrobial Resistance
- Drug Discovery
- Antimicrobial Pharmacology
- Systems Pharmacology
- Computational Biology
- Bioinformatics
- Polymyxin
- Colistin
- Pharmacodynamics
- Pharmacokinetics
- Acinetobacter baumannii
- Klebsiella pneumoniae
- Pseudomonas aeruginosa
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2004 2023
Dolomite Single Cell RNA Seq System / 4 CO2 Incubators / Class II Biological Safety Hoods
Rosenbluh, J., Firestein, R., Daly, R. J., Hertzog, P. J., Mitchell, C. A., Li, J., Southey, M. C., Jenkins, B. J., Ryan, M. T. & Traven, A.
1/01/18 → 31/12/18
Project: Research
Combating Deadly Gram-negative Lung Infections: An Inhalation and Systems Approach
Li, J. & Velkov, T.
National Institutes of Health (NIH US)
1/08/17 → 31/07/21
Project: Research
Targeting the Urgent Need for New Antibiotics against Gram-negative ‘Superbugs’
Li, J., Velkov, T., Roberts, K. D., Thompson, P. & Nation, R. L.
1/08/17 → 31/07/22
Project: Research
An integrated virtual cell approach towards elucidating the systems pharmacology of antibiotics against Pseudomonas aeruginosa
Li, J., Song, J. & Schreiber, F.
National Health & Medical Research Council (NHMRC)
1/01/17 → 31/12/20
Project: Research
Optimising inhaled polymyxins as a vital therapy for pulmonary infections: A novel biochemical, molecular imaging and systems pharmacology approach
Li, J., Chan, H., Velkov, T., Zhou, T. Q. & Zhou, F.
National Health & Medical Research Council (NHMRC)
1/01/16 → 31/12/18
Project: Research
Research Output 2001 2018
Alterations of Metabolic and Lipid Profiles in Polymyxin-Resistant Pseudomonas aeruginosa
Han, M-L., Zhu, Y., Creek, D. J., Lin, Y-W., Anderson, D., Shen, H-H., Tsuji, B., Gutu, A. D., Moskowitz, S. M., Velkov, T. & Li, J. 1 Jun 2018 In : Antimicrobial Agents and Chemotherapy. 62, 6, 14 p., e02656-17Research output: Contribution to journal › Article › Research › peer-review
Assessment and modelling of antibacterial combination regimens
Rao, G. G., Li, J., Garonzik, S. M., Nation, R. L. & Forrest, A. Jul 2018 In : Clinical Microbiology and Infection. 24, 7, p. 689-696 8 p.Research output: Contribution to journal › Review Article › Research › peer-review
Broad activity of diphenyleneiodonium analogues against Mycobacterium tuberculosis, malaria parasites and bacterial pathogens
Nguyen, N., Wilson, D. W., Nagalingam, G., Triccas, J. A., Schneider, E. K., Li, J., Velkov, T. & Baell, J. 25 Mar 2018 In : European Journal of Medicinal Chemistry. 148, p. 507-518 12 p.Research output: Contribution to journal › Article › Research › peer-review
Co-Delivery of Ciprofloxacin and Colistin in Liposomal Formulations with Enhanced In Vitro Antimicrobial Activities against Multidrug Resistant Pseudomonas aeruginosa
Wang, S., Yu, S., Lin, Y., Zou, P., Chai, G., Yu, H. H., Wickremasinghe, H., Shetty, N., Ling, J., Li, J. & Zhou, Q. T. 1 Oct 2018 In : Pharmaceutical Research. 35, 10, 13 p., 187Research output: Contribution to journal › Article › Research › peer-review
Comparative analysis of phosphoethanolamine transferases involved in polymyxin resistance across ten clinically relevant gram-negative bacteria
Huang, J., Zhu, Y., Han, M., Li, M., Song, J., Velkov, T., Li, C. & Li, J. Apr 2018 In : International Journal of Antimicrobial Agents. 51, 4, p. 586-593 8 p.Research output: Contribution to journal › Article › Research › peer-review
Activities 2011 2011
- 1 Submissions to industry or govt committees, commissions and inquiries
Drug Delivery, Disposition and Dynamics
Li, J. (Member)9 Nov 2011 → 9 Sep 2099
Activity: Submissions to industry or govt committees, commissions and inquiries
Press / Media
Genome scale model of a superbug
Trevor James Lithgow, Jian Li & Jiangning Song
16/03/18 → 30/03/18
2 media contribution
Press/Media: Research
A$9.8 million fight against superbugs
Jian Li, William Neil Charman, Jiangning Song, Anthony Wayne Purcell, Paul John Hertzog, Darren John Creek, Roger Leigh Nation, Jurgen Bullita & John Dallas Boyce
24/04/14
1 media contribution
Press/Media: Public Engagement Activities