Projects per year
Personal profile
Biography
Professor Jian Li (PhD 2002) is Head of the Antimicrobial Systems Pharmacology Laboratory at the Biomedicine Discovery Institute, Monash University. He is a Web of Science 2015 - 2017 Highly Cited Researcher in Pharmacology & Toxicology. Dr Li has an internationally recognised track record in the pharmacology of polymyxins and the discovery of novel, safer polymyxins. He has 285 publications (including 225 on polymyxins alone) with 12,500 citations and an h-index of 55. Dr Li is an Editor of the International Journal of Antimicrobial Agents and an Associate Editor of BMC Microbiology. He is an invited reviewer for 152 international journals and grant/fellowship applications for 14 international funding bodies. His research is funded by NIH, Australian National Health and Medical Research Council (NHMRC), Australian Research Council (ARC), pharmaceutical companies and other grant bodies. Dr Li has received numerous awards, including Australian Leadership Award (2013), Australian National Health and Medical Research Council’s Ten of the Best Research Projects (2014) and Australian Academy of Science Jacques Miller Medal (2017).
Monash teaching commitment
Supervisor of PhD, Masters and Honours students
Keywords
- Antimicrobial Resistance
- Drug Discovery
- Antimicrobial Pharmacology
- Systems Pharmacology
- Computational Biology
- Bioinformatics
- Polymyxin
- Colistin
- Pharmacodynamics
- Pharmacokinetics
- Acinetobacter baumannii
- Klebsiella pneumoniae
- Pseudomonas aeruginosa
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2004 2023
Integrative systems pharmacology, neutron reflectometry and molecular dynamics approaches to unravelling the interaction between polymyxins and bacterial membranes
Li, J., Shen, H., Velkov, T., Song, J. & Schreiber, F.
1/01/18 → 31/12/22
Project: Research
Targeting the Urgent Need for New Antibiotics against Gram-negative ‘Superbugs’
Li, J., Velkov, T., Roberts, K., Thompson, P. & Nation, R.
1/08/17 → 31/07/22
Project: Research
Combating Deadly Gram-negative Lung Infections: An Inhalation and Systems Approach
Li, J. & Velkov, T.
National Institutes of Health (NIH US)
1/08/17 → 31/07/21
Project: Research
An integrated virtual cell approach towards elucidating the systems pharmacology of antibiotics against Pseudomonas aeruginosa
Li, J., Song, J. & Schreiber, F.
National Health & Medical Research Council (NHMRC)
1/01/17 → 31/12/20
Project: Research
Research Output 2001 2019
Comparative metabolomics and transcriptomics reveal multiple pathways associated with polymyxin killing in pseudomonas aeruginosa
Han, M-L., Zhu, Y., Creek, D. J., Lin, Y-W., Gutu, A. D., Hertzog, P., Purcell, T., Shen, H-H., Moskowitz, S. M., Velkov, T. & Li, J., 1 Jan 2019, In : mSystems. 4, 1, 18 p., e00149-18.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Contemporary Anti-Ebola Drug Discovery Approaches and Platforms
Schneider-Futschik, E. K., Hoyer, D., Khromykh, A. A., Baell, J. B., Marsh, G. A., Baker, M. A., Li, J. & Velkov, T., 1 Nov 2019, In : ACS Infectious Diseases. 5, 1, p. 35-48 14 p.Research output: Contribution to journal › Article › Research › peer-review
Effects of the antibiotic component on in-vitro bacterial killing, physico-chemical properties, aerosolization and dissolution of a ternary-combinational inhalation powder formulation of antibiotics for pan-drug resistant Gram-negative lung infections
Mangal, S., Huang, J., Shetty, N., Park, H., Lin, Y., Yu, H. H., Zemlyanov, D., Velkov, T., Li, J. & Zhou, Q. T., 20 Apr 2019, In : International Journal of Pharmaceutics. 561, p. 102-113 12 p.Research output: Contribution to journal › Article › Research › peer-review
Novel polymyxin combination with the antiretroviral zidovudine exerts synergistic killing against Ndm-producing multidrug-resistant klebsiella pneumoniae
Lin, Y-W., Rahim, N. A., Zhao, J., Han, M-L., Yu, H. H., Wickremasinghe, H., Chen, K., Wang, J., Paterson, D. L., Zhu, Y., Rao, G. G., Zhou, Q. T., Forrest, A., Velkov, T. & Li, J., 1 Apr 2019, In : Antimicrobial Agents and Chemotherapy. 63, 4, 11 p., e02176-18.Research output: Contribution to journal › Article › Research › peer-review
Understanding the Impacts of Surface Compositions on the In-Vitro Dissolution and Aerosolization of Co-Spray-Dried Composite Powder Formulations for Inhalation
Mangal, S., Xu, R., Park, H., Zemlyanov, D., Shetty, N., Lin, Y-W., Morton, D., Chan, H-K., Li, J. & Zhou, T. Q., 1 Jan 2019, In : Pharmaceutical Research. 36, 15 p.Research output: Contribution to journal › Article › Research › peer-review
Activities 2011 2011
- 1 Submissions to industry or govt committees, commissions and inquiries
Drug Delivery, Disposition and Dynamics
Jian Li (Member)9 Nov 2011 → 9 Sep 2099
Activity: External Academic Engagement › Submissions to industry or govt committees, commissions and inquiries
Press / Media
AI tool to boost genomic data analysis
Jiangning Song, Roger Daly & Jian Li
25/04/19
1 media contribution
Press/Media: Research
Genome scale model of a superbug
Trevor Lithgow, Jian Li & Jiangning Song
16/03/18 → 30/03/18
2 media contributions
Press/Media: Research
A$9.8 million fight against superbugs
Jian Li, William Charman, Jiangning Song, Anthony Purcell, Paul Hertzog, Darren Creek, Roger Nation, Jurgen Bullita & John Boyce
24/04/14
1 media contribution
Press/Media: Public Engagement Activities