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Personal profile

Biography

Professor Jian Li (PhD 2002) is an elected Fellow of the American Academy of Microbiology and Head of the Antimicrobial Systems Pharmacology Laboratory at the Biomedicine Discovery Institute, Monash University. He is a Web of Science 2015 - 2017 Highly Cited Researcher in Pharmacology & Toxicology. Dr Li has an internationally recognised track record in the pharmacology of polymyxins and the discovery of novel, safer polymyxins. He has 337 publications (including 266 on polymyxins alone) with 17,324 citations and an h-index of 65. Dr Li is an Editor of the International Journal of Antimicrobial Agents and an Associate Editor of BMC Microbiology and Frontiers in Microbiology. He is an invited reviewer for 167 international journals and grant/fellowship applications for 18 international funding bodies. His research is funded by NIH, Australian National Health and Medical Research Council (NHMRC), Australian Research Council (ARC), pharmaceutical companies and other grant bodies. Dr Li has received numerous awards, including Australian Leadership Award (2013), Australian National Health and Medical Research Council’s Ten of the Best Research Projects (2014) and Australian Academy of Science Jacques Miller Medal (2017).

Monash teaching commitment

Supervisor of PhD, Masters and Honours students

Research area keywords

  • Antimicrobial Resistance
  • Drug Discovery
  • Antimicrobial Pharmacology
  • Systems Pharmacology
  • Computational Biology
  • Bioinformatics
  • Polymyxin
  • Colistin
  • Pharmacodynamics
  • Pharmacokinetics
  • Acinetobacter baumannii
  • Klebsiella pneumoniae
  • Pseudomonas aeruginosa

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Projects

Research Output

Complete genome sequence and genome-scale metabolic modelling of Acinetobacter baumannii type strain ATCC 19606

Zhu, Y., Lu, J., Zhao, J., Zhang, X., Yu, H. H., Velkov, T. & Li, J., Apr 2020, In : International Journal of Medical Microbiology. 310, 3, 11 p., 151412.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Graphene encapsulation enabled high-throughput atom probe tomography of liquid specimens

Qiu, S., Garg, V., Zhang, S., Chen, Y., Li, J., Taylor, A., Marceau, R. K. W. & Fu, J., Sep 2020, In : Ultramicroscopy. 216, 7 p., 113036.

Research output: Contribution to journalArticleResearchpeer-review

iLearn: an integrated platform and meta-learner for feature engineering, machine-learning analysis and modeling of DNA, RNA and protein sequence data

Chen, Z., Zhao, P., Li, F., Marquez-Lago, T. T., Leier, A., Revote, J., Zhu, Y., Powell, D. R., Akutsu, T., Webb, G. I., Chou, K-C., Smith, A. I., Daly, R. J., Li, J. & Song, J., 21 May 2020, In : Briefings in Bioinformatics. 21, 3, p. 1047-1057 11 p., bbz041.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)

Metabolomics Study of the Synergistic Killing of Polymyxin B in Combination with Amikacin against Polymyxin-Susceptible and -Resistant Pseudomonas aeruginosa

Hussein, M., Han, M-L., Zhu, Y., Zhou, Q. T., Lin, Y-W., Hancock, R. E. W., Hoyer, D., Creek, D. J., Li, J. & Velkov, T., Jan 2020, In : Antimicrobial Agents and Chemotherapy. 64, 1, 16 p., e01587-19.

Research output: Contribution to journalArticleResearchpeer-review

Pan-transcriptomic analysis identified common differentially expressed genes of Acinetobacter baumannii in response to polymyxin treatments

Li, M., Aye, S. M., Ahmed, M. U., Han, M-L., Li, C., Song, J., Boyce, J. D., Powell, D. R., Azad, M. A. K., Velkov, T., Zhu, Y. & Li, J., 22 May 2020, (Accepted/In press) In : Molecular Omics. 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Activities

  • 1 Submissions to industry or govt committees, commissions and inquiries

Drug Delivery, Disposition and Dynamics

Jian Li (Member)

9 Nov 20119 Sep 2099

Activity: External Academic EngagementSubmissions to industry or govt committees, commissions and inquiries

Press / Media

AI tool to boost genomic data analysis

Jiangning Song, Roger Daly & Jian Li

25/04/19

1 Media contribution

Press/Media: Research

Genome scale model of a superbug

Trevor Lithgow, Jian Li & Jiangning Song

16/03/1830/03/18

2 Media contributions

Press/Media: Research