Projects per year
Personal profile
Biography
Dr Jessica Stringer's research is focused on understand how chemical and environmental impacts affect genome integrity, genetic and non-genetic inheritance and female fertility. She obtained her PhD from The University of Melbourne in 2012 where she investigated the evolution and functional importance of genomic imprinting; the first known example of inherited epigenetic information that mediates parent-specific gene expression essential for development. She then undertook her postdoctoral studies with As/Prof Western (Hudson Institute of Medical Research), where she identified a new mechanism regulating transmission of epigenetic information from parent to offspring. In 2016 Dr Stringer came to work with As/Prof Hutt at Monash University to investigate importance of DNA damage repair for oocyte quality, female fertility and offspring health. Significantly she identified the DNA repair mechanisms responsible for safe-guarding primordial follicle oocytes. Her current research aims to i) improve women’s health and fertility during maternal aging, ii) develop new therapeutic strategies to protect female fertility during anti-cancer therapy and iii) ensure that these therapeutic strategies do not impact on offspring health.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- Epigenetics
- Gene Expression
- Gene Regulation
- Genetics
- Genomic imprinting
- Germline
- Inheritance
- Reproduction
Network
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Deciphering incomplete penetrance of subfertility
Crismani, W., Stringer, J. & Hoffmann, E.
1/01/22 → 31/12/25
Project: Research
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SCIREQ inExpose system
Winship, A., Carroll, J., Bourke, J., Simonds, S., Heng, T., Hutt, K., Stringer, J., Western, P., Coelho Marques, F. & Abud, H.
1/10/21 → 31/12/22
Project: Research
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Platform Access - Developing an automated counting method for measuring the ovarian reserve
9/08/21 → 31/12/22
Project: Research
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Defining the epigenetic origins of maternally inherited disease.
Western, P., Gardner, D., Voss, A. K., van den Buuse, M., Adelson, D. L., Sims, N. A., Hutt, K., Dickinson, H., Stringer, J., Hill, R. & Gibson, W.
1/01/18 → 31/12/20
Project: Research
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Beyond apoptosis: evidence of other regulated cell death pathways in the ovary throughout development and life
Stringer, J., Alesi, L. R., Winship, A. & Hutt, K., 2023, (Accepted/In press) In: Human Reproduction Update. p. 1-23 23 p., dmad005.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access -
The future of fertility preservation for women treated with chemotherapy
Alesi, L. R., Nguyen, Q-N., Stringer, J., Winship, A. & Hutt, K., 2023, In: Reproduction and Fertility. 4, 2, 22 p.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access -
An essential role for Polycomb Repressive Complex 2 in the mouse ovary
Prokopuk, L., Jarred, E. G., Blücher, R. O., McLaughlin, E. A., Stringer, J. M. & Western, P. S., 17 Feb 2022, In: Reproduction. 163, 3, p. 167-182 16 p.Research output: Contribution to journal › Article › Research › peer-review
1 Citation (Scopus) -
Checkpoint inhibitor immunotherapy diminishes oocyte number and quality in mice
Winship, A., Alesi, L. R., Sant, S., Stringer, J., Cantavenera, A., Hegarty, T. S., Lliberos Requesens, C., Liew, S. H. J., Sarma, U., Griffiths, M., Zerafa, N., Fox, S. B., Brown, E., Caramia, F., Zareie, P., La Gruta, N., Phillips, K. A., Strasser, A., Loi, S. & Hutt, K., Aug 2022, In: Nature Cancer. 3, 8, p. 1-13 13 p.Research output: Contribution to journal › Article › Research › peer-review
7 Citations (Scopus) -
Inhibin Inactivation in Female Mice Leads to Elevated FSH Levels, Ovarian Overstimulation, and Pregnancy Loss
Walton, K. L., Goney, M. P., Peppas, Z., Stringer, J. M., Winship, A., Hutt, K., Goodchild, G., Maskey, S., Chan, K. L., Brûlé, E., Bernard, D. J., Stocker, W. A. & Harrison, C. A., Apr 2022, In: Endocrinology. 163, 4, 13 p., bqac025.Research output: Contribution to journal › Article › Research › peer-review
3 Citations (Scopus)
Press/Media
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Discovery of a new approach to fertility preservation in women undergoing treatment for cancer
18/05/20
1 Media contribution
Press/Media: Article/Feature
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Australian researchers investigate whether supplements can improve egg quality and fertility in women
26/02/20
1 Media contribution
Press/Media: Article/Feature
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New Study Sheds Light On How A Father's Health Affects His Offspring
7/12/18
1 Media contribution
Press/Media: Article/Feature
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Selective imprinting: how the wallaby controls growth of its young
27/08/12
1 Media contribution
Press/Media: Article/Feature