Projects per year
Personal profile
Biography
Dr Jessica Stringer's research is focused on understand how chemical and environmental impacts affect genome integrity, genetic and non-genetic inheritance and female fertility. She obtained her PhD from The University of Melbourne in 2012 where she investigated the evolution and functional importance of genomic imprinting; the first known example of inherited epigenetic information that mediates parent-specific gene expression essential for development. She then undertook her postdoctoral studies with As/Prof Western (Hudson Institute of Medical Research), where she identified a new mechanism regulating transmission of epigenetic information from parent to offspring. In 2016 Dr Stringer came to work with As/Prof Hutt at Monash University to investigate importance of DNA damage repair for oocyte quality, female fertility and offspring health. Significantly she identified the DNA repair mechanisms responsible for safe-guarding primordial follicle oocytes. Her current research aims to i) improve women’s health and fertility during maternal aging, ii) develop new therapeutic strategies to protect female fertility during anti-cancer therapy and iii) ensure that these therapeutic strategies do not impact on offspring health.
Research area keywords
- Epigenetics
- Gene Expression
- Gene Regulation
- Genetics
- Genomic imprinting
- Germline
- Inheritance
- Reproduction
Network
Projects
- 2 Finished
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Defining the epigenetic origins of maternally inherited disease.
Western, P., Gardner, D., Voss, A. K., van den Buuse, M., Adelson, D. L., Sims, N., Hutt, K., Dickinson, H., Stringer, J., Hill, R. & Gibson, W.
1/01/18 → 31/12/20
Project: Research
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Research output
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NMN does not protect the ovarian reserve from cancer treatments
Stringer, J., Groenewegen, E., Liew, S. H. & Hutt, K., Feb 2020, In : Reproduction. 159, 2, p. 105-113 9 p.Research output: Contribution to journal › Article › Research › peer-review
2 Citations (Scopus) -
Oocytes can efficiently repair DNA double-strand breaks to restore genetic integrity and protect offspring health
Stringer, J. M., Winship, A., Zerafa, N., Wakefield, M. & Hutt, K., 26 May 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 117, 21, p. 11513–11522 10 p.Research output: Contribution to journal › Article › Research › peer-review
7 Citations (Scopus) -
A step toward making human oocytes
Stringer, J. M. & Western, P. S., 3 Jan 2019, In : Nature Biotechnology. 37, 1, p. 24-25 2 p.Research output: Contribution to journal › Editorial › Other
1 Citation (Scopus) -
Evaluation of mitochondria in oocytes following γ-irradiation
Wang, Q., Stringer, J. M., Liu, J. & Hutt, K. J., 27 Dec 2019, In : Scientific Reports. 9, 1, 9 p., 19941.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile -
Examination of the ovotoxicity of 5-fluorouracil in mice
Lambouras, M., Liew, S. H., Horvay, K., Abud, H. E., Stringer, J. M. & Hutt, K. J., Jun 2018, In : Journal of Assisted Reproduction and Genetics. 35, 6, p. 1053-1060 8 p.Research output: Contribution to journal › Article › Research › peer-review
7 Citations (Scopus)