Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Collaborations and top research areas from the last five years
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Harnessing Endogenous Opioids to Treat Gut Motility Disorders and Pain
Poole, D. (Primary Chief Investigator (PCI)), Valant, C. (Chief Investigator (CI)), Carbone, S. (Chief Investigator (CI)), Mobbs, J. (Chief Investigator (CI)), Thal, D. (Associate Investigator (AI)), Scammells, P. (Associate Investigator (AI)), King, S. K. (Associate Investigator (AI)), Imlach, W. (Associate Investigator (AI)), Hamilton, J. (Associate Investigator (AI)) & Veldhuis, N. (Associate Investigator (AI))
1/01/23 → 31/12/26
Project: Research
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Discovery of a lead molecule for development into a non-hormonal male contraceptive
Mobbs, J. (Primary Chief Investigator (PCI)), Ventura, S. (Chief Investigator (CI)), Thal, D. (Chief Investigator (CI)) & Bennetts, F. (Chief Investigator (CI))
1/01/23 → 30/04/24
Project: Research
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High-resolution cryo-EM using a common LaB6 120-keV electron microscope equipped with a sub-200-keV direct electron detector
Venugopal, H., Mobbs, J., Taveneau, C., Fox, D. R., Vuckovic, Z., Gulati, S., Knott, G., Grinter, R., Thal, D., Mick, S., Czarnik, C. & Ramm, G., 3 Jan 2025, In: Science Advances. 11, 1, 11 p., eadr0438.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
Molecular basis of ligand binding and receptor activation at the human A3 adenosine receptor
Zhang, L., Mobbs, J. I., Bennetts, F. M., Venugopal, H., Nguyen, A. T. N., Christopoulos, A., van der Es, D., Heitman, L. H., May, L. T., Glukhova, A. & Thal, D. M., Dec 2025, In: Nature Communications. 16, 1, 19 p., 7674.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
Cholesterol-dependent dynamic changes in the conformation of the type 1 cholecystokinin receptor affect ligand binding and G protein coupling
Harikumar, K. G., Zhao, P., Cary, B. P., Xu, X., Desai, A. J., Dong, M., Mobbs, J. I., Toufaily, C., Furness, S. G. B., Christopoulos, A., Belousoff, M. J., Wootten, D., Sexton, P. M. & Miller, L. J., Jul 2024, In: PLoS Biology. 22, 7, 26 p., e3002673.Research output: Contribution to journal › Article › Research › peer-review
Open Access3 Citations (Scopus) -
Structural insights into the human P2X1 receptor and ligand interactions
Bennetts, F. M., Venugopal, H., Glukhova, A., Mobbs, J. I., Ventura, S. & Thal, D. M., Dec 2024, In: Nature Communications. 15, 1, 14 p., 8418.Research output: Contribution to journal › Article › Research › peer-review
Open Access4 Citations (Scopus) -
Complimentary electrostatics dominate T-cell receptor binding to a psoriasis-associated peptide antigen presented by human leukocyte antigen C∗06:02
Anand, S., Littler, D. R., Mobbs, J. I., Braun, A., Baker, D. G., Tennant, L., Purcell, A. W., Vivian, J. P. & Rossjohn, J., Jul 2023, In: Journal of Biological Chemistry. 299, 7, 10 p., 104930.Research output: Contribution to journal › Article › Research › peer-review
Open Access6 Citations (Scopus)