Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Collaborations and top research areas from the last five years
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Harnessing Endogenous Opioids to Treat Gut Motility Disorders and Pain
Poole, D., Valant, C., Carbone, S., Mobbs, J., Thal, D., Scammells, P., King, S. K., Imlach, W., Hamilton, J. A. & Veldhuis, N.
1/01/23 → 31/12/26
Project: Research
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Discovery of a lead molecule for development into a non-hormonal male contraceptive
Mobbs, J., Ventura, S., Thal, D. & Bennetts, F.
1/01/23 → 30/04/24
Project: Research
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Cholesterol-dependent dynamic changes in the conformation of the type 1 cholecystokinin receptor affect ligand binding and G protein coupling
Harikumar, K. G., Zhao, P., Cary, B. P., Xu, X., Desai, A. J., Dong, M., Mobbs, J. I., Toufaily, C., Furness, S. G. B., Christopoulos, A., Belousoff, M. J., Wootten, D., Sexton, P. M. & Miller, L. J., Jul 2024, In: PLoS Biology. 22, 7, 26 p., e3002673.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Complimentary electrostatics dominate T-cell receptor binding to a psoriasis-associated peptide antigen presented by human leukocyte antigen C∗06:02
Anand, S., Littler, D. R., Mobbs, J. I., Braun, A., Baker, D. G., Tennant, L., Purcell, A. W., Vivian, J. P. & Rossjohn, J., Jul 2023, In: Journal of Biological Chemistry. 299, 7, 10 p., 104930.Research output: Contribution to journal › Article › Research › peer-review
Open Access3 Citations (Scopus) -
Cryo-EM structures of human arachidonate 12S-lipoxygenase bound to endogenous and exogenous inhibitors
Mobbs, J. I., Black, K. A., Tran, M., Burger, W. A. C., Venugopal, H., Holman, T. R., Holinstat, M., Thal, D. M. & Glukhova, A., 5 Oct 2023, In: Blood. 142, 14, p. 1233–1242 22 p.Research output: Contribution to journal › Article › Research › peer-review
11 Citations (Scopus) -
Pharmacological hallmarks of allostery at the M4 muscarinic receptor elucidated through structure and dynamics
Vuckovic, Z., Wang, J., Pham, V., Mobbs, J. I., Belousoff, M. J., Bhattarai, A., Burger, W. A. C., Thompson, G., Yeasmin, M., Nawaratne, V., Leach, K., van der Westhuizen, E. T., Khajehali, E., Liang, Y. L., Glukhova, A., Wootten, D., Lindsley, C. W., Tobin, A., Sexton, P., Danev, R., & 4 others , 30 May 2023, In: eLife. 12, 52 p., e83477.Research output: Contribution to journal › Article › Research › peer-review
Open Access14 Citations (Scopus) -
The impact of cryo-EM on determining allosteric modulator-bound structures of G protein-coupled receptors
Zhang, L., Mobbs, J. I., May, L. T., Glukhova, A. & Thal, D. M., Apr 2023, In: Current Opinion in Structural Biology. 79, 9 p., 102560.Research output: Contribution to journal › Review Article › Research › peer-review
9 Citations (Scopus)