20112023

Research activity per year

Personal profile

Biography

A/Prof Jeremy Grummet, MBBS, MS, FRACS, is a practising academic urologist who is expert in prostate cancer diagnosis and treatment. His overarching aim is to provide value-based care for maximal wellbeing.

He has pioneered transperineal biopsy (via the skin) as a safer technique for performing prostate biopsy, avoiding the risks of sepsis associated with the traditional transrectal (via the rectum) technique. Transperineal biopsy is now both the recommended standard of care in official clinical guidelines and the most used prostate biopsy technique in Australia. Jeremy is a leader of the global TREXIT movement, aiming to end the practice of transrectal biopsy by the end of 2022.

He is the co-founder of MRI PRO, a unique globally used online training program whose aim is to improve the accuracy and standards of prostate MRI reporting around the world. MRI PRO is achieving that aim, with its prostate MRI cases and webinar videos being viewed thousands of times by radiologists and urologists from over 90 countries.

Jeremy is the only non-European Member of the European Association of Urology (EAU) Prostate Cancer Guidelines Panel. These Guidelines are used throughout Europe and endorsed globally outside North America, including by the Urological Society of Australia and New Zealand (USANZ).

He is also a Co-Primary Investigator on the LIBERATE prospective clinical registry of focal brachytherapy for single focus intermediate-risk localised prostate cancer, now recruiting in Australia. Now that accurate imaging is available to determine the precise location of cancer within the prostate, it makes sense to research highly targeted treatment to minimise side effects. This approach is already standard of care for other solid organ cancers, such as breast cancer.

Research interests

Recognising that most of the controversies surrounding prostate cancer start with its diagnosis, Assoc Prof Grummet has now turned his research focus onto prostate cancer diagnostics including MRI and biopsy, and supervises Master of Surgery and Bachelor of Medical Science researchers in this field. Topics under investigation include the risk of biopsy sepsis, diagnostic accuracy, the role of MRI-targeted biopsy, and PSMA PET scanning.

Monash teaching commitment

Prostate MRI Training Course

  • Test your diagnostic skills on 300 cases.
  • Track your progress.
  • Earn CME/CPD points.
  • Get MRI PRO Accredited.

Students will analyse 300 full prostate MRI cases, performed to PIRADS (Prostate Imaging Reporting and Data System) v2.1 standard, online. For each case, students will analyse the MRI and will be required to give their answers in four domains, which are all clinically focused.

  • Assessment Task 1 (AT1): What the PIRADS score is, as the indicator of likelihood that significant prostate cancer is present.
  • AT2: If the MRI is deemed positive for a suspicious lesion (PIRADS 3 – 5), how many lesions are present.
  • AT3: If the MRI is positive, what staging features there are with regard to extraprostatic extension, seminal vesicle involvement, lymph node metastasis and bony metastasis.
  • AT4: If lesions are present, where in the prostate a biopsy would most likely hit that lesion.

 

Following completion of each case, students submit their answers and are immediately shown the correct answer and where their answer diverges from it for each component. Students are also shown the full histology of the prostate for all cases positive for cancer, as well as annotated MRI images with lesions circled, for immediate feedback.

Students can also return to the MRI images after each case to review where they have got their answer right or wrong.

To progress to the next case, students must submit their answer, ensuring interactive learning. They will also be able to track their own progress and improvement in accuracy using the My Progress feature, showing a detailed breakdown of their strengths and weaknesses in PIRADS scoring of each MRI. Students must successfully complete AT1, AT2 and AT4 for at least 20 consecutive cases with at least 80% accuracy.

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

External positions

Deputy Director of Urology, Alfred Health

Research area keywords

  • Urology
  • Prostate Cancer

Collaborations and top research areas from the last five years

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