Projects per year
Personal profile
Biography
Jeremy completed his PhD in microbiology at The University of Queensland in 2011 as part of the Advanced Water Management Center. He then moved to San Diego, USA to complete a postdoctoral position working under the tutelage of Prof. Forest Rohwer at San Diego State University. While there he studied the interactions of bacteriophage with mucosal surfaces that provided a non-host-derived immunity.
Jeremy moved to Monash in 2016 to establish his independent laboratory in Bacteriophage Biology. In 2020, Jeremy joined the Monash Centre to Impact AMR, established to reverse the evolution of AMR using non-drug solutions. Jeremy is a member of the community empowerment initiative, to help raise awareness of AMR.
Research interests
Our lab studies bacteriophage – viruses that infect bacteria – and specifically investigates the tri-partite symbioses formed between bacteriophage, their bacterial hosts and eukaryotic cells and surfaces.
Bacteriophage (or phage for short) are the most abundant and diverse microbe found in the body. Phages control and manipulate bacterial populations, prevent infection and disease and have important roles in regulating the microbiome and body that have not yet been fully elucidated.
A major study system in our lab is the mucosal surface – a microbe-rich, protective barrier that covers the covers the active epithelium of the body, including the gut, lung and urinary tract among other locales. The Bacteriophage Adherence to Mucus (BAM) model describes a novel phage-based immune system, whereby phages adhering to mucus reduce bacterial colonization of these surfaces, protecting them from infection and disease.
We are an experimental biology lab and utilise a range of cross-disciplinary techniques to investigate fundamental and mechanistic bacteriophage biology.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- Bacteriophage
- microbiome
- mucosal surface
- cross-disciplinary
- superbugs
- AMR
- phage therapy
- Antibiotic resistance
Network
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Effectiveness of UVGI in comparison to HEPA filtration at eliminating virus laden aerosol
Joosten, S., Landry, S., Barr, J. & Subedi, D.
8/03/23 → 30/06/23
Project: Research
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Aerosol Infection Research: Better mOdels to Reduce iNdoor Exposure (AIRBORNE)
Subbarao, K., Geard, N., Buising, K. L., Irving, L. B., Baz, M., Schofield, R., Monty, J. P., Joosten, S., McGain, F., Sullivan, S. G., Marshall, C. L., Landry, S., Barr, J. & Kainer, M.
Medical Research Future Fund (MRFF)
1/01/22 → 30/05/25
Project: Research
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Discovery of Novel Bacteriophage with the Capacity to Modulate Gut Bacteria
2/12/21 → 1/12/25
Project: Research
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Towards the Translation of Synergistic Phage-Polymyxin Combination Therapy against Pandrug-resistant Klebsiella pneumoniae: A Systems Approach
Li, J., Barr, J., Lin, W., Rao, G. & Schooley, R. T.
16/08/21 → 31/07/23
Project: Research
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Bacterial concentration and detection using an ultrasonic nanosieve within a microfluidic device
Ang, B., Habibi, R., Kett, C., Chin, W. H., Barr, J. J., Tuck, K. L., Neild, A. & Cadarso, V. J., 1 Jan 2023, In: Sensors and Actuators B: Chemical. 374, 9 p., 132769.Research output: Contribution to journal › Article › Research › peer-review
1 Citation (Scopus) -
A metabolic perspective into antimicrobial tolerance and resistance
Bhusal, R. P., Barr, J. J. & Subedi, D., Mar 2022, In: The Lancet Microbe. 3, 3, p. e160-e161 2 p.Research output: Contribution to journal › Comment / Debate › Other › peer-review
Open Access1 Citation (Scopus) -
Bacteriophages evolve enhanced persistence to a mucosal surface
Chin, W. H., Kett, C., Cooper, O., Museler, D., Zhang, Y., Bamert, R. S., Patwa, R., Woods, L. C., Devendran, C., Korneev, D., Tiralongo, J., Lithgow, T., McDonald, M. J., Neild, A. & Barr, J. J., 5 Jul 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 27, 10 p., e2116197119.Research output: Contribution to journal › Article › Research › peer-review
4 Citations (Scopus) -
Comparative metabolomics revealed key pathways associated with the synergistic killing of multidrug-resistant Klebsiella pneumoniae by a bacteriophage-polymyxin combination
Han, M-L., Nang, S. C., Lin, Y-W., Zhu, Y., Yu, H. H., Wickremasinghe, H., Barlow, C. K., Creek, D. J., Crawford, S., Rao, G., Dai, C., Barr, J. J., Chan, K., Turner Schooley, R., Velkov, T. & Li, J., 2022, In: Computational and Structural Biotechnology Journal. 20, p. 485-495 11 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access5 Citations (Scopus) -
Fit-Tested N95 Masks Combined With Portable High-Efficiency Particulate Air Filtration Can Protect Against High Aerosolized Viral Loads Over Prolonged Periods at Close Range
Landry, S. A., Subedi, D., Barr, J. J., MacDonald, M. I., Dix, S., Kutey, D. M., Mansfield, D., Hamilton, G. S., Edwards, B. A. & Joosten, S. A., 15 Jul 2022, In: The Journal of Infectious Diseases. 226, 2, p. 199-207 9 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access6 Citations (Scopus)
Prizes
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Faculty Of Science Awards: Research Excellence by an Early Career Researcher
Barr, Jeremy (Recipient), 2021
Prize: Prize (including medals and awards)
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Vice-Chancellor’s Award for Research Excellence by an Early Career Researchers (STEM)
Barr, Jeremy (Recipient), 2021
Prize: Prize (including medals and awards)
Activities
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Jeremy Barr on phage journey through the body & dynamics of immunity: March 14, 2022
Jeremy Barr (Contributor)
2022Activity: Community Talks, Presentations, Exhibitions and Events › Public lecture/debate/seminar
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Richard Alm
Jeremy Barr (Host)
2022 → …Activity: Hosting a visitor types › Hosting an academic or industry visitor
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Viruses of Microbes
Jeremy Barr (Session chair)
2022Activity: Participating in or organising an event types › Contribution to conference
Press/Media
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Which Mask Is The Most Effective In Protecting You Against COVID-19?
19/05/22
1 item of Media coverage
Press/Media: Research
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Scientists discover new phage therapy combination to combat antibiotic-resistance
Jeremy Barr, Fernando Gordillo Altamirano & Anton Peleg
9/05/22
1 item of Media coverage
Press/Media: Research
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Using bacteriophages to bring back antimicrobials sensitivity in Acinetobacter baumannii with Dr. Jeremy Barr
22/03/22
1 Media contribution
Press/Media: Blogs, Podcasts and Social Media › Podcasts
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Superbugs have an arsenal of defences – but we've found a new way around them
12/01/21 → 28/01/21
5 items of Media coverage, 1 Media contribution
Press/Media: Research
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Our growing resistance to antibiotics may be an ongoing health threat
14/01/21
1 item of Media coverage
Press/Media: Article/Feature