Projects per year
Personal profile
Biography
Dr. Jennifer Payne is an EMBL Australia Research Fellow in the Cryle Group at the Victorian Node, based in the Department of Biochemistry and Molecular Biology at Monash University.
Jennifer completed her Ph.D. with Prof Marilyn Anderson at La Trobe University, Melbourne, Australia where her passion for host defense peptides began with discovering the mechanism of action of plant defensins and their interaction with cell surfaces. Her Ph.D. thesis was in the top 4% and recognised with the Nancy Millis Medal in 2016.
Shifting into the antibiotic field Jennifer now works on glycopeptide antibiotics in the lab of A/Prof Max Cryle at Monash University and EMBL Australia. Her work on creating a new revolution of antibiotics to combat drug-resistant superbugs. These new drugs against superbugs are not your typical antibiotic, in that they don't just directly kill the bacteria, instead, they combine multiple mechanisms of action into one molecule. These novel antibiotics unmask the superbugs and harness and modulate the innate immune system to ensure clearance of drug-resistant infections. These novel antibiotics resulted in her being awarded both the 2018 Hugh Roger's fellowship from Melbourne-Boston Sister City Association and the VESKI Victorian fellowship. With these fellowships, Jennifer spent 6 months working in collaboration at Harvard University in 2018 learning and developing microfluidic techniques to monitor innate immune cell migration and clearance of bacteria in real-time.
Research interests
- Diversifing glycopeptide antibiotics to kill resistant bacterial pathogens
- Innate immune cell recruitment and clearance of superbugs
- Host defence peptide interaction with innate immune cells for the clearance of superbugs
- Novel antibiotic combinations for the improved killing of multi-resistant pathogens
Education/Academic qualification
Biochemistry, PhD, La Trobe University
Research area keywords
- Antibiotics
- Biochemistry
- Antibacterials
- Peptide
- Drug Resistance
- Antimicrobials
Network
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Antibiotic-chemoattractants enhance neutrophil clearance of Staphylococcus aureus
Payne, J. A. E., Tailhades, J., Ellett, F., Kostoulias, X., Fulcher, A. J., Fu, T., Leung, R., Louch, S., Tran, A., Weber, S. A., Schittenhelm, R. B., Lieschke, G. J., Qin, C. H., Irima, D., Peleg, A. Y. & Cryle, M. J., Dec 2021, In: Nature Communications. 12, 1, 15 p., 6157.Research output: Contribution to journal › Article › Research › peer-review
Open Access2 Citations (Scopus) -
Rapid screening method of Saccharomyces cerevisiae mutants using calcofluor white and aniline blue
Perrine-Walker, F. & Payne, J., Sep 2021, In: Brazilian Journal of Microbiology. 52, 3, p. 1077-1086 10 p.Research output: Contribution to journal › Article › Research › peer-review
1 Citation (Scopus) -
Staphylococcus aureus entanglement in self-assembling β-peptide nanofibres decorated with vancomycin
Payne, J. A. E., Kulkarni, K., Izore, T., Fulcher, A. J., Peleg, A. Y., Aguilar, M. I., Cryle, M. J. & Del Borgo, M. P., 7 May 2021, In: Nanoscale Advances. 3, 9, p. 2607-2616 10 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access2 Citations (Scopus) -
Surgical mesh coatings for infection control and temperature sensing: An in-vitro investigation
Houshyar, S., Mirzadeh, N., Pillai, M. M., Saha, T., Khalid, A., Bhattacharyya, A., Dekiwadia, C., Zizhou, R., Cryle, M. J., Payne, J. A. E., Bhargava, S., Fox, K. & Tran, P. A., Dec 2021, In: OpenNano. 5, 12 p., 100032.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
The interaction with fungal cell wall polysaccharides determines the salt tolerance of antifungal plant defensins
Bleackley, M. R., Dawson, C. S., Payne, J. A. E., Harvey, P. J., Rosengren, K. J., Quimbar, P., Garcia-Ceron, D., Lowe, R., Bulone, V., van der Weerden, N. L., Craik, D. J. & Anderson, M. A., Dec 2019, In: The Cell Surface. 5, 12 p., 100026.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile4 Citations (Scopus)
Prizes
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So you think you can pitch? Competition
Payne, Jennifer (Recipient), Dec 2020
Prize: Prize (including medals and awards)
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Activities
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Frontiers in Antibiotics (Journal)
Jennifer Payne (Peer reviewer)
2022Activity: Publication peer-review and editorial work types › Editorial responsibility
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Krishani Dave (Masters Student)
Jennifer Payne (Supervisor) & Max Cryle (Supervisor)
2021Activity: Other Teaching Engagements and non-HDR Supervisions › Non-HDR Supervisions
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Rachel Cass (Summer Scholarship)
Jennifer Payne (Supervisor) & Max Cryle (Supervisor)
Nov 2021 → Feb 2022Activity: Other Teaching Engagements and non-HDR Supervisions › Non-HDR Supervisions
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MONASH UNIVERSITY (Organisational unit)
Jennifer Payne (Inventor), Max Cryle (Inventor), Anton Peleg (Inventor) & Julien Tailhades (Inventor)
23 Apr 2020Activity: Industry, Government and Philanthropy Engagement and Partnerships › Patents › Patent (Provisional)
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Hexima Limited (External organisation)
Nicole Louise van der Weerden (Inventor), Marilyn A Anderson (Inventor) & Jennifer Payne (Inventor)
25 Feb 2020Activity: Industry, Government and Philanthropy Engagement and Partnerships › Patents › Patent (Provisional)
Press / Media
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Interview with Dr Jenn on the ABC Radio on comeback of infections & PenPal program
8/03/22
1 item of Media coverage
Press/Media: Expert Comment
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Antimicrobial Peptide Structures: An Interview with Dr. Jennifer Payne
17/01/22
1 Media contribution
Press/Media: Blogs, Podcasts and Social Media › Podcasts
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Faculty of Opinions recommendation
Jennifer Payne, Max Cryle, Julien Tailhades, Alex Fulcher, Felix Ellett, Daniel Irima, Xenia Kostoulias, Ryan Leung, Steph Louch, Amy Tran, Severin Weber, Ralf Schittenhelm, Graham Lieschke, Chengxue Helena Qin, Anton Peleg & Ting Fu
3/12/21
1 item of Media coverage
Press/Media: Article/Feature
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The Naked Scientist Podcast interview Dr Payne on Antibiotics upgraded to tackle superbugs
11/11/21
1 Media contribution
Press/Media: Blogs, Podcasts and Social Media › Podcasts
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BBC5 Live Interview of Dr Jennifer Payne on an antimicrobial that helps arm the immune system
31/10/21
1 Media contribution
Press/Media: Blogs, Podcasts and Social Media › Podcasts