Projects per year
Personal profile
Biography
Jeff performs research on mitochondrial replacement therapy in the Biomedicine Discovery Institute. Previously, he led laboratories researching the role of epigenetics in mammalian germ cell development at the City of Hope National Medical Center in Los Angeles, The University of Melbourne, and the Murdoch Children’s Research Institute, Melbourne. For several years he instructed the 'Molecular Embryology of the Mouse Course' at the Cold Spring Harbor Laboratory, New York, and has directed institutional facilities for making preclinical models of disease.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Network
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Understanding non-genetic inheritance in health and disease
Western, P., Adelson, D. L., Gibson, W., Blewitt, M. E., Lee, H. J., Sims, N. A., Gouil, Q. & Mann, J.
1/01/23 → 31/12/26
Project: Research
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NHOMD: Mitigating the risks of mitochondrial donation
Carroll, J., Mann, J., Herbert, M. & Zander-Fox, D. L.
1/01/21 → 31/12/24
Project: Research
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(1) FemtoJet 4i microinjector (Eppendorf). (2) IVF Cube (Astec) tri-gas incubator (regulated carbon dioxide and oxygen)
Carroll, J., Mann, J., Herbert, M. & Zander-Fox, D.
1/02/21 → 1/12/22
Project: Research
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Investigation into epigenetic defects and new therapeutic strategy in ATRX mutated gliomas
Wong, L., Voon, H. P. J. & Mann, J.
1/09/18 → 31/08/20
Project: Research
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Mouse models of paediatric brainstem high grade glioma
Australian Communities Foundation
1/01/15 → 31/12/15
Project: Research
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Depletion of oocyte dynamin-related protein 1 shows maternal-effect abnormalities in embryonic development
Adhikari, D., Lee, I. W., Al-Zubaidi, U., Liu, J., Zhang, Q. H., Yuen, W. S., He, L., Winstanley, Y., Sesaki, H., Mann, J. R., Robker, R. L. & Carroll, J., Jun 2022, In: Science Advances. 8, 24, 15 p., eabl8070.Research output: Contribution to journal › Article › Research › peer-review
Open Access4 Citations (Scopus) -
Histone H3.3 phosphorylation promotes heterochromatin formation by inhibiting H3K9/K36 histone demethylase
Udugama, M., Vinod, B., Chan, F. L., Hii, L., Garvie, A., Collas, P., Kalitsis, P., Steer, D., Das, P. P., Tripathi, P., Mann, J. R., Voon, H. P. J. & Wong, L. H., 6 May 2022, In: Nucleic Acids Research. 50, 8, p. 4500-4514 15 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access3 Citations (Scopus) -
HENMT1 is involved in the maintenance of normal female fertility in the mouse
Hutt, K. J., Lim, S. L., Zhang, Q-H., Gonzalez, M., O'Connor, A. E., Jo Merriner, D., Liew, S. H., Al-Zubaidi, U., Yuen, W. S., Adhikari, D., Robker, R. L., Mann, J. R., Carroll, J. & O'Bryan, M. K., Nov 2021, In: Molecular Human Reproduction. 27, 11, p. 1-12 12 p.Research output: Contribution to journal › Article › Research › peer-review
1 Citation (Scopus) -
Mutations inhibiting KDM4B drive ALT activation in ATRX-mutated glioblastomas
Udugama, M., Hii, L., Garvie, A., Cervini, M., Vinod, B., Chan, F. L., Das, P. P., Mann, J. R., Collas, P., Voon, H. P. J. & Wong, L. H., 10 May 2021, In: Nature Communications. 12, 1, 11 p., 2584.Research output: Contribution to journal › Article › Research › peer-review
Open Access11 Citations (Scopus) -
Generation and characterisation of a parkin-Pacrg knockout mouse line and a Pacrg knockout mouse line
Stephenson, S. E. M., Aumann, T. D., Taylor, J. M., Riseley, J. R., Li, R., Mann, J. R., Tomas, D. & Lockhart, P. J., 14 May 2018, In: Scientific Reports. 8, 1, 11 p., 7528.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile12 Citations (Scopus)