Projects per year
Personal profile
Biography
Dr. Jha is a Senior Research Fellow in the Department of Diabetes at the School of Translational Medicine, where he leads innovative research focused on discovering novel therapeutic targets and biomarkers for diabetes, kidney disease, and cardiorenal syndrome.
He earned his PhD from Monash University in 2014, with his thesis providing the scientific rationale for clinical trials investigating NOX inhibitors in diabetic kidney disease. In 2015, he began his postdoctoral research at the Baker Heart and Diabetes Institute. His contributions were soon recognised with the prestigious Juvenile Diabetes Research Foundation (JDRF) International Postdoctoral Fellowship in 2016, enabling him to further advance his work in diabetes and renal disease.
In 2017, Dr. Jha was awarded the highly competitive NHMRC Peter Doherty Early Career Research Fellowship, which coincided with his transition to the newly established Monash Diabetes Department. Demonstrating his commitment to international research collaboration, he spent time as a visiting scholar at the German Diabetes Centre in Düsseldorf in 2022.
Dr. Jha is actively engaged in the scientific community through memberships in several professional societies, including the Australian Diabetes Society (ADS), the Australian and New Zealand Society of Nephrology (ANZSN), the American Society of Nephrology (ASN), and the European Association for the Study of Diabetes (EASD).
His research has been published in leading journals in the fields of diabetes, nephrology, and oxidative stress, and is widely cited—with over 3,500 citations and an H-index of 24 as of July 2025—underscoring the impact and relevance of his work. He has consistently secured competitive funding, including multiple grants from Diabetes Australia (2020, 2022, 2023, and 2024), and in 2025, he was awarded the FMNHS Future Leader Postdoctoral Fellowship—a testament to his sustained excellence and leadership in the field.
With a strong track record of impactful research and a clear vision for improving health outcomes, Dr. Jha continues to lead advances in translational science in diabetes and kidney disease.
Research interests
- Oxidative stress – inflammation – fibrosis axis in diabetes and related complications
- Human 3D kidney organoids
- Translation of novel therapeutic targets
- NOX pathways
- Predictive tools and biomarkers of diabetes and kidney disease
Research area keywords
- Diabetes
- Kidney Disease
- Oxidative stress
- NADPH oxidases
- Inflammation
- Fibrosis
- Kidney organoids
- Biomarkers
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
Collaborations and top research areas from the last five years
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Decoding NOX5: A Novel Non-Invasive Biomarker for Early Detection of Kidney Dysfunction in Obesity and Diabetes
Jha, J. (Primary Chief Investigator (PCI)), Jandeleit-Dahm, K. (Associate Investigator (AI)), Sourris, K. (Associate Investigator (AI)) & Shaw, J. (Associate Investigator (AI))
15/01/26 → 31/12/27
Project: Research
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Combating diabetic nephropathy by targeting the NADPH oxidase NOX5
Jha, J. (Partner Investigator (PI))
Project: Research
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FMNHS Future Leader Postdoctoral Fellowship
Jha, J. (Primary Chief Investigator (PCI))
1/01/25 → 31/12/25
Project: Research
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The role of oxidative stress in Chronic Kidney Disease (CKD)
Aboolian, A., Younes, J., Romero, A., Jha, J. C., Jandeleit-Dahm, K. & Meister, J., 23 Jan 2025, Molecular Basis of Oxidative Stress: Chemistry, Toxicology, Disease Pathogenesis, Diagnosis, and Therapeutics. Villamena, F. A. & Forman, H. J. (eds.). 2nd ed. Hoboken New Jersey USA: John Wiley & Sons, p. 417-436 20 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter (Book) › Research › peer-review
1 Link opens in a new tab Citation (Scopus) -
Diabetes and Renal Complications: An Overview on Pathophysiology, Biomarkers and Therapeutic Interventions
Jha, R., Lopez-Trevino, S., Kankanamalage, H. R. & Jha, J. C., May 2024, In: Biomedicines. 12, 5, 23 p., 1098.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access108 Link opens in a new tab Citations (Scopus) -
Endothelial NOX5 Obliterates the Reno-Protective Effect of Nox4 Deletion by Promoting Renal Fibrosis via Activation of EMT and ROS-Sensitive Pathways in Diabetes
Jandeleit-Dahm, K. A. M., Kankanamalage, H. R., Dai, A., Meister, J., Lopez-Trevino, S., Cooper, M. E., Touyz, R. M., Kennedy, C. R. J. & Jha, J. C., Apr 2024, In: Antioxidants. 13, 4, 18 p., 396.Research output: Contribution to journal › Article › Research › peer-review
Open Access8 Link opens in a new tab Citations (Scopus) -
Elucidating NOX5 as a Potential Therapeutic Target and a Biomarker of Kidney Disease in Diabetes FR-PO376
Jha, J., Kankanamalage, H. R., Jaquet, V., Cooper, M. E. & Jandeleit-Dahm, K. A. M., Nov 2023, In: Journal of the American Society of Nephrology. 34, 11S, p. 507 1 p.Research output: Contribution to journal › Meeting Abstract › peer-review
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Nox5: a promising therapeutic target for diabetic kidney disease
Jha, J. C., Dai, A., Kankanamalage, H. R., Meister, J., Vincent, J., Cooper, M. E. & Jandeleit-Dahm, K., Sept 2023, In: Diabetologia. 66, Suppl 1, p. S71 1 p., 132.Research output: Contribution to journal › Meeting Abstract › peer-review
Prizes
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AMREP best paper award and prizes, Melbourne, Australia
Jha, J. (Recipient), 2015
Prize: Prize (including medals and awards)
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Basic Science Finalist Award and Prize, APCN/ANZSN, Perth, Australia
Jha, J. (Recipient), 2016
Prize: Prize (including medals and awards)
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Basic Science Runner up Award, Australian New Zealand Society of Nephrology, Sydney, Australia
Jha, J. (Recipient), 2018
Prize: Prize (including medals and awards)
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Basic Science Runner Up Award, Australian New Zealand Society of Nephrology (ANZSN), Australia
Jha, J. (Recipient), 2020
Prize: Prize (including medals and awards)
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Best Abstracts Award, Asia pacific congress of Nephrology (APCN) & CSN 2018, Beijing, China
Jha, J. (Recipient), 2018
Prize: Prize (including medals and awards)
Activities
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Honours Student Supervision
Jha, J. (Supervisor)
1 Mar 2024 → 30 Nov 2024Activity: Other Teaching Engagements and non-HDR Supervisions › Non-HDR Supervisions
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Annual Meeting of the European-Association-for-the- Study-of-Diabetes (EASD) 2024
Jha, J. (Speaker)
2024Activity: Participating in or organising an event types › Contribution to conference
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Research in Action (HUP3990) Student Supervision
Jha, J. (Supervisor)
1 Mar 2024 → 31 Jul 2024Activity: Other Teaching Engagements and non-HDR Supervisions › Non-HDR Supervisions
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Australasian Diabetes Congress 2023 (ADS/ADEA Annual Scientific Meeting)
Jha, J. (Session chair)
2023Activity: Participating in or organising an event types › Contribution to workshop, seminar, course
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Australasian Diabetes Congress 2023 (ADS/ADEA Annual Scientific Meeting)
Jha, J. (Speaker)
2023Activity: Participating in or organising an event types › Contribution to conference
Press/Media
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https://www.monash.edu/medicine/news/latest/2022-articles/new-diabetic-kidney-disease-target-raises-hopes.
1/07/22
1 Media contribution
Press/Media: Blogs, Podcasts and Social Media › Social Media Article
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https://www.monash.edu/medicine/news/latest/2022-articles/new-anti-inflammatory-approach-may-damage-kidneys,-monash-scientists-find
2/02/22
1 Media contribution
Press/Media: Blogs, Podcasts and Social Media › Social Media Article
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http://ccsmonash.blogspot.com/2019/11/answering-fundamental-question-about.html
1/11/19
1 Media contribution
Press/Media: Blogs, Podcasts and Social Media › Social Media Article
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STM diabetes researcher honoured by award
6/09/19
1 Media contribution
Press/Media: Blogs, Podcasts and Social Media › Blogs
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http://ccsmonash.blogspot.com/2018/06/amrep-student-journal-club-kicks-off.html
11/06/18
1 Media contribution
Press/Media: Blogs, Podcasts and Social Media › Blogs