• B112, Pharmacology, 9 Ancora Imparo Way

    3800 Clayton

    Australia

1987 …2020

Research output per year

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Research Output

2020

A new pathway to airway relaxation: Targeting the "other" cyclase in asthma

Lam, M. & Bourke, J. E., 1 Jan 2020, In : American Journal of Respiratory Cell and Molecular Biology. 62, 1, p. 3-4 2 p.

Research output: Contribution to journalEditorialOtherpeer-review

Open Access
File
2019

Cardioprotective actions of the annexin-A1 N-terminal peptide, AC2-26, against myocardial infarction

Qin, C. X., Rosli, S., Deo, M., Cao, N., Walsh, J., Tate, M., Alexander, A. E., Donner, D., Horlock, D., Li, R., Kiriazis, H., Lee, M. K. S., Bourke, J. E., Yang, Y., Murphy, A. J., Du, X-J., Gao, X. M. & Ritchie, R. H., 3 Apr 2019, In : Frontiers in Pharmacology. 10, 16 p., 269.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
7 Citations (Scopus)

Interleukin-1 receptor antagonist protects newborn mice against pulmonary hypertension

Bui, C. B., Kolodziej, M., Lamanna, E., Elgass, K., Sehgal, A., Rudloff, I., Schwenke, D. O., Tsuchimochi, H., Kroon, M. A. G. M., Cho, S. X., Maksimenko, A., Cholewa, M., Berger, P. J., Young, M. J., Bourke, J. E., Pearson, J. T., Nold, M. F. & Nold-Petry, C. A., 11 Jul 2019, In : Frontiers in Immunology. 10, JULY, 15 p., 1480.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2 Citations (Scopus)

NOx in exhaled breath condensate is related to allergic sensitization in young and middle-aged adults

Aldakheel, F. M., Bourke, J. E., Thomas, P. S., Matheson, M. C., Abramson, M. J., Hamilton, G. S., Lodge, C. J., Thompson, B. R., Haydn Walters, E., Allen, K. J., Erbas, B., Perret, J. L., Dharmage, S. C. & Lowe, A. J., Feb 2019, In : Clinical & Experimental Allergy. 49, 2, p. 171-179 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2 Citations (Scopus)

Regulation of Airway Smooth Muscle Contraction in Health and Disease

Lam, M., Lamanna, E. & Bourke, J. E., 24 Jun 2019, Smooth Muscle Spontaneous Activity: Physiological and Pathological Modulation. Hashitani, H. & Lang, R. J. (eds.). Singapore: Springer, p. 381-422 42 p. (Advances in Experimental Medicine and Biology; vol. 1124).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

4 Citations (Scopus)
2018

Serelaxin as a novel therapeutic opposing fibrosis and contraction in lung diseases

Lam, M., Royce, S. G., Samuel, C. S. & Bourke, J. E., Jul 2018, In : Pharmacology and Therapeutics. 187, p. 61-70 10 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

8 Citations (Scopus)
2017

Airway remodelling and inflammation in asthma are dependent on the extracellular matrix protein fibulin-1c

Liu, G., Cooley, M. A., Nair, P. M., Donovan, C., Hsu, A. C., Jarnicki, A. G., Haw, T. J., Hansbro, N. G., Ge, Q., Brown, A. C., Tay, H., Foster, P. S., Wark, P. A., Horvat, J. C., Bourke, J. E., Grainge, C. L., Argraves, W. S., Oliver, B. G., Knight, D. A., Burgess, J. K. & 1 others, Hansbro, P. M., 1 Dec 2017, In : Journal of Pathology. 243, 4, p. 510-523 14 p.

Research output: Contribution to journalArticleResearchpeer-review

24 Citations (Scopus)

Latrophilin receptors: Novel bronchodilator targets in asthma

Faiz, M. A., Donovan, C., Nieuwenhuis, M. A. E., Van Den Berge, M., Postma, D. S., Yao, S., Park, C. Y., Hirsch, R., Fredberg, J. J., Tjin, G., Halayko, A. J., Rempel, K. L., Ward, J. P. T., Lee, T., Bossé, Y., Nickle, D. C., Obeidat, M., Vonk, J. M., Black, J. L., Oliver, B. G. & 4 others, Krishnan, R., McParland, B., Bourke, J. E. & Burgess, J. K., 1 Jan 2017, In : Thorax. 72, 1, p. 74-82 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
6 Citations (Scopus)

Lung health in a changing world

Peters, M. J. & Bourke, J. E., 20 Nov 2017, In : The Medical Journal of Australia. 207, 10, p. 426-428 3 p.

Research output: Contribution to journalEditorialOtherpeer-review

Small-molecule-biased formyl peptide receptor agonist compound 17b protects against myocardial ischaemia-reperfusion injury in mice

Qin, C. X., May, L. T., Li, R., Cao, N., Rosli, S., Deo, M., Alexander, A. E., Horlock, D., Bourke, J. E., Yang, Y. H., Stewart, A. G., Kaye, D. M., Du, X. J., Sexton, P. M., Christopoulos, A., Gao, X. M. & Ritchie, R. H., 7 Feb 2017, In : Nature Communications. 8, 13 p., 14232.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
30 Citations (Scopus)
2016

Airway remodeling and hyperreactivity in a model of bronchopulmonary dysplasia and their modulation by IL-1Ra

Royce, S. G., Nold, M. F., Bui, C. B-Q., Donovan, C., Lam, M., Lamanna, E., Rudloff, I., Bourke, J. E. & Nold-Petry, C. A., 1 Dec 2016, In : American Journal of Respiratory Cell and Molecular Biology. 55, 6, p. 858-868 11 p.

Research output: Contribution to journalArticleResearchpeer-review

16 Citations (Scopus)

Influenza A virus infection and cigarette smoke impair bronchodilator responsiveness to β-adrenoceptor agonists in mouse lung

Donovan, C., Seow, H. J., Bourke, J. E. & Vlahos, R., May 2016, In : Clinical Science. 130, 10, p. 829-837 9 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Neonatal pneumococcal colonisation caused by Influenza A infection alters lung function in adult mice

FitzPatrick, M., Royce, S. G., Langenbach, S., McQualter, J., Reading, P. C., Wijburg, O., Anderson, G. P., Stewart, A., Bourke, J. & Bozinovski, S., 2016, In : Scientific Reports. 6, p. 1 - 12 12 p., 22751.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
4 Citations (Scopus)

Relationships between adult asthma and oxidative stress markers and pH in exhaled breath condensate: A systematic review

Aldakheel, F. M., Thomas, P. S., Bourke, J. E., Matheson, M. C., Dharmage, S. C. & Lowe, A. J., Jun 2016, In : Allergy. 71, 6, p. 741-757 17 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

28 Citations (Scopus)

Serelaxin elicits bronchodilation and enhances β-Adrenoceptor-mediated airway relaxation

Lam, M., Royce, S. G., Donovan, C., Jelinic, M., Parry, L. J., Samuel, C. S. & Bourke, J. E., 27 Oct 2016, In : Frontiers in Pharmacology. 7, 406, 18 p., 406.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
7 Citations (Scopus)

Targeting the IL-33/IL-13 axis for respiratory viral infections

Donovan, C., Bourke, J. E. & Vlahos, R., Apr 2016, In : Trends in Pharmacological Sciences. 37, 4, p. 252-261 10 p.

Research output: Contribution to journalArticleOtherpeer-review

17 Citations (Scopus)
2015

Alteration of airway reactivity and reduction of ryanodine receptor expression by cigarette smoke in mice

Donovan, C., Seow, H. J., Royce, S. G., Bourke, J. E. & Vlahos, R., 2015, In : American Journal of Respiratory Cell and Molecular Biology. 53, 4, p. 471 - 478 8 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Lipopolysaccharide does not alter small airway reactivity in mouse lung slices

Donovan, C., Royce, S. G., Vlahos, R. & Bourke, J. E., 2015, In : PLoS ONE. 10, 3, 16 p., e0122069.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
4 Citations (Scopus)

Rosiglitazone elicits in vitro relaxation in airways and precision cut lung slices from a mouse model of chronic allergic airways disease

Donovan, C., Bailey, S. R., Tran, J., Haitsma, G., Ibrahim, Z. A., Foster, S. R., Tang, M. L. K., Royce, S. G. & Bourke, J. E., 2015, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 309, 10, p. 1219 - 1228 10 p.

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)
2014

Novel small airway bronchodilator responses to rosiglitazone in mouse lung slices

Bourke, J. E., Bai, Y., Donovan, C., Esposito, J. G., Tan, X. & Sanderson, M. J., 1 Apr 2014, In : American Journal of Respiratory Cell and Molecular Biology. 50, 4, p. 748-756 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
18 Citations (Scopus)

Prostaglandin E2 elicits greater bronchodilation than salbutamol in mouse intrapulmonary airways in lung slices

FitzPatrick, M., Donovan, C. & Bourke, J. E., Jun 2014, In : Pulmonary Pharmacology and Therapeutics. 28, 1, p. 68-76 9 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Rosiglitazone is a superior bronchodilator compared to chloroquine and β-adrenoceptor agonists in mouse lung slices

Donovan, C., Simoons, M., Esposito, J., Cheong, J. N., FitzPatrick, M. & Bourke, J. E., 12 Mar 2014, In : Respiratory Research. 15, 1, 12 p., 29.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
9 Citations (Scopus)

TLR2 activation causes tachyphylaxis to β2-Agonists in vitro and ex vivo: Modelling bacterial exacerbation

Alkhouri, H., Rumzhum, N. N., Rahman, M. M., Fitzpatrick, M., De Pedro, M., Oliver, B. G., Bourke, J. E. & Ammit, A. J., Sep 2014, In : Allergy. 69, 9, p. 1215-1222 8 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)
2013

Differential effects of allergen challenge on large and small airway reactivity in mice

Donovan, C., Royce, S. G., Esposito, J., Tran, J., Ibrahim, Z. A., Tang, M. L. K., Bailey, S. & Bourke, J. E., 6 Sep 2013, In : PLoS ONE. 8, 9, p. 1-8 8 p., e74101.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
20 Citations (Scopus)

Emerging mediators of airway smooth muscle dysfunction in asthma

Yeganeh, B., Xia, C., Movassagh, H., Koziol-White, C., Chang, Y., Al-Alwan, L., Bourke, J. E. & Oliver, B. G. G., Feb 2013, In : Pulmonary Pharmacology and Therapeutics. 26, 1, p. 105-111 7 p.

Research output: Contribution to journalArticleResearchpeer-review

21 Citations (Scopus)
2012

PPAR γ ligands regulate noncontractile and contractile functions of airway smooth muscle: Implications for asthma therapy

Donovan, C., Tan, X. & Bourke, J. E., 2012, In : PPAR Research. 2012, 13 p., 809164.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
12 Citations (Scopus)
2011

Collagen remodelling by airway smooth muscle is resistant to steroids and β2-agonists

Bourke, J. E., Li, X., Foster, S. R., Wee, E., Dagher, H., Ziogas, J., Harris, T., Bonacci, J. V. & Stewart, A. G., 1 Jan 2011, In : European Respiratory Journal. 37, 1, p. 173-182 10 p.

Research output: Contribution to journalArticleResearchpeer-review

22 Citations (Scopus)
2010

Effects of PPARγ ligands on TGF-β1-induced epithelial-mesenchymal transition in alveolar epithelial cells

Tan, X., Dagher, H., Hutton, C. A. & Bourke, J. E., 23 Feb 2010, In : Respiratory Research. 11, 21.

Research output: Contribution to journalArticleResearchpeer-review

50 Citations (Scopus)
2009

Lipid metabolites as regulators of airway smooth muscle function

Clarke, D. L., Dakshinamurti, S., Larsson, A. K., Ward, J. E. & Yamasaki, A., Oct 2009, In : Pulmonary Pharmacology and Therapeutics. 22, 5, p. 426-435 10 p.

Research output: Contribution to journalArticleResearchpeer-review

21 Citations (Scopus)

Measurement and impact of remodeling in the lung: airway neovascularization in asthma

Bischof, R., Bourke, J. E., Hirst, S. J., Meeusen, E. N. T., Snibson, K. & Van Der Velden, J., 2009, In : Proceedings of the American Thoracic Society. 6, 8, p. 673 - 677 5 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Tissue and matrix influences on airway smooth muscle function

Burgess, J. K., Ceresa, C., Johnson, S. R., Kanabar, V., Moir, L. M., Nguyen, TT. T. B., Oliver, B. G. G., Schuliga, M. & Ward, J., Oct 2009, In : Pulmonary Pharmacology and Therapeutics. 22, 5, p. 379-387 9 p.

Research output: Contribution to journalArticleResearchpeer-review

39 Citations (Scopus)
2008

Airway smooth muscle bidirectional interactions with extracellular matrix

Ward, J. E. & Hirst, S. J., 2008, Airway Smooth Muscle in Asthma and COPD. Chung, K. F. (ed.). 1st ed. UK: John Wiley & Sons, p. 105 - 126 22 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

3 Citations (Scopus)

Proliferation is not increased in airway myofibroblasts isolated from asthmatics

Ward, J. E., Harris, T., Bamford, T., Mast, A., Pain, M. C. F., Robertson, C., Smallwood, D., Tran, T., Wilson, J. & Stewart, A. G., Aug 2008, In : European Respiratory Journal. 32, 2, p. 362-371 10 p.

Research output: Contribution to journalArticleResearchpeer-review

42 Citations (Scopus)
2007

Peroxisome proliferator activated receptor ligands as regulators of airway inflammation and remodelling in chronic lung disease

Ward, J. E. & Tan, X., 2007, In : PPAR Research. 14983.

Research output: Contribution to journalReview ArticleResearchpeer-review

34 Citations (Scopus)
2006

The PPARγ ligand, rosiglitazone, reduces airways hyperresponsiveness in a murine model of allergen-induced inflammation

Ward, J. E., Fernandes, D. J., Taylor, C. C., Bonacci, J. V., Quan, L. & Stewart, A. G., Feb 2006, In : Pulmonary Pharmacology and Therapeutics. 19, 1, p. 39-46 8 p.

Research output: Contribution to journalArticleResearchpeer-review

35 Citations (Scopus)
2004

PPARγ ligands, 15-deoxy-Δ 12,14-prostaglandin J 2 and rosiglitazone regulate human cultured airway smooth muscle proliferation through different mechanisms

Ward, J. E., Gould, H., Harris, T., Bonacci, J. V. & Stewart, A. G., Feb 2004, In : British Journal of Pharmacology. 141, 3, p. 517-525 9 p.

Research output: Contribution to journalArticleResearchpeer-review

57 Citations (Scopus)
1995

Collateral development and angiogenesis after major artery ligation does not alter hindquarter vascular reactivity in conscious rabbits

Ward, J. E. & Angus, J. A., 1995, In : Journal of Cardiovascular Pharmacology. 26, 1, p. 96-106 11 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)
1993

Acute and chronic inhibition of nitric oxide synthase in conscious rabbits: Role of nitric oxide in the control of vascular tone

Ward, J. E. & Angus, J. A., 1993, In : Journal of Cardiovascular Pharmacology. 21, 5, p. 804-814 11 p.

Research output: Contribution to journalArticleResearchpeer-review

41 Citations (Scopus)
1992

Relationship between the sympatholytic action of nebivolol and hypotension

Ward, J. E., Coles, P., Cox, H., Eisenhofer, G. & Angus, J. A., 1992, In : Journal of Cardiovascular Pharmacology. 20, 1, p. 115-124 10 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Release of endothelium-derived relaxing factor from resistance arteries in hypertension

Angus, J. A., Dyke, A. C., Jennings, G. L., Korner, P. I., Sudhir, K., Ward, J. E. & Wright, C. E., 1992, In : Kidney International, Supplement. 37

Research output: Contribution to journalArticleResearchpeer-review

34 Citations (Scopus)
1991

Effect of estradiol and progesterone on phosphatidylinositol metabolism in the uterine epithelium of the mouse

Bourke, J. E., Dank, S., Wilce, P. A. & Martin, L., 1 Jan 1991, In : Journal of Steroid Biochemistry and Molecular Biology. 39, 3, p. 337-342 6 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Reactivity of canine isolated epicardial collateral coronary arteries: Relation to vessel structure

Angus, J. A., Ward, J. E., Smolich, J. J. & McPherson, G. A., 1991, In : Circulation Research. 69, 5, p. 1340-1352 13 p.

Research output: Contribution to journalArticleResearchpeer-review

29 Citations (Scopus)
1990

Coronary collateral arteries have impiared vasoconstrictor activity but normal vasodilator properties

Angus, J. A., Smolich, J., Ward, J. E. & McPherson, G. A., 1990, In : European Journal of Pharmacology. 183, 6, 1 p.

Research output: Contribution to journalArticleResearchpeer-review

1988

Developmental, functional and molecular studies of peptides in the adrenal medulla

Livett, B., Wan, D., Marley, P., Khalil, Z. & Bourke, J. E., 1988, Progress in Catecholamine Research. AR Liss

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

The effects of neosurugatoxin on evoked catecholamine secretion from bovine adrenal chromaffin cells

Bourke, J. E., Bunn, S., Marley, P. & Livett, B., 1 Jan 1988, In : British Journal of Pharmacology. 93, 2, p. 275-280 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
9 Citations (Scopus)
1987

Direct and Continuous Detection of ATP Secretion from Primary Monolayer Cultures of Bovine Adrenal Chromaffin Cells

White, T. D., Bourke, J. E. & Livett, B. G., 1987, In : Journal of Neurochemistry. 49, 4, p. 1266-1273 8 p.

Research output: Contribution to journalArticleResearchpeer-review

27 Citations (Scopus)