• B112, Pharmacology, 9 Ancora Imparo Way

    3800 Clayton

    Australia

1987 …2020

Research output per year

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Personal profile

Biography

Dr Jane Bourke is Assocaite Professor in Pharmacology at Monash University, where she leads the Respiratory Pharmacology Group. Her research focuses on identifying improved therapeutic strategies in chronic lung diseases. She has unique expertise in Australia with an innovative technique in which changes in intrapulmonary airway and artery lumen area can be visualized in situ in lung slices. With numerous local and international collaborators, she has applied this approach in preclinical studies in animal models of asthma, COPD, infection, pulmonary hypertension and bronchopulmonary dysplasia to study disease mechanisms and test novel therapeutic interventions. More recently, she has commenced studies using human tissues to facilitate clinical translation.

Jane has published her research in specialist respiratory and pharmacology journals (Thorax, European Respiratory Journal, American Journal of Respiratory Cell and Molecular Biology, American Journal of Physiology (Lung), Respiratory Research, Trends in Pharmacological Sciences, British Journal of Pharmacology) as well as multidisciplinary journals (Nature Communications, Clinical Science, Scientific Reports). She regularly reviews manuscripts and is currently an Editorial Board Member for Frontiers in Physiology and Scientific Reports.

Jane has completed several terms as an elected member of the Board of the Thoracic Society of Australia and New Zealand (TSANZ), where she chaired the Education and Research Subcommittee and Conference Committee. She was also President of the Asia Pacific Society of Respirology Congress, held in Sydney in 2017. Jane is currently a member of the Executive Committee of the Respiratory Structure and Function Assembly of the American Thoracic Society (ATS). She was made a Fellow of TSANZ in 2019 and Fellow of ATS in 2020 in recognitions of her contributions to respiratory research.

Research area keywords

  • Asthma
  • COPD
  • Pulmonary Hypertension
  • Lung
  • Airway
  • Artery
  • Smooth Muscle
  • Calcium
  • Bronchodilator
  • Vasodilator

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Projects

Research Output

A new pathway to airway relaxation: Targeting the "other" cyclase in asthma

Lam, M. & Bourke, J. E., 1 Jan 2020, In : American Journal of Respiratory Cell and Molecular Biology. 62, 1, p. 3-4 2 p.

Research output: Contribution to journalEditorialOtherpeer-review

Open Access
File

Cardioprotective actions of the annexin-A1 N-terminal peptide, AC2-26, against myocardial infarction

Qin, C. X., Rosli, S., Deo, M., Cao, N., Walsh, J., Tate, M., Alexander, A. E., Donner, D., Horlock, D., Li, R., Kiriazis, H., Lee, M. K. S., Bourke, J. E., Yang, Y., Murphy, A. J., Du, X-J., Gao, X. M. & Ritchie, R. H., 3 Apr 2019, In : Frontiers in Pharmacology. 10, 16 p., 269.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
7 Citations (Scopus)

Interleukin-1 receptor antagonist protects newborn mice against pulmonary hypertension

Bui, C. B., Kolodziej, M., Lamanna, E., Elgass, K., Sehgal, A., Rudloff, I., Schwenke, D. O., Tsuchimochi, H., Kroon, M. A. G. M., Cho, S. X., Maksimenko, A., Cholewa, M., Berger, P. J., Young, M. J., Bourke, J. E., Pearson, J. T., Nold, M. F. & Nold-Petry, C. A., 11 Jul 2019, In : Frontiers in Immunology. 10, JULY, 15 p., 1480.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2 Citations (Scopus)

NOx in exhaled breath condensate is related to allergic sensitization in young and middle-aged adults

Aldakheel, F. M., Bourke, J. E., Thomas, P. S., Matheson, M. C., Abramson, M. J., Hamilton, G. S., Lodge, C. J., Thompson, B. R., Haydn Walters, E., Allen, K. J., Erbas, B., Perret, J. L., Dharmage, S. C. & Lowe, A. J., Feb 2019, In : Clinical & Experimental Allergy. 49, 2, p. 171-179 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2 Citations (Scopus)

Regulation of Airway Smooth Muscle Contraction in Health and Disease

Lam, M., Lamanna, E. & Bourke, J. E., 24 Jun 2019, Smooth Muscle Spontaneous Activity: Physiological and Pathological Modulation. Hashitani, H. & Lang, R. J. (eds.). Singapore: Springer, p. 381-422 42 p. (Advances in Experimental Medicine and Biology; vol. 1124).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

3 Citations (Scopus)

Prizes

American Thoracic Society Neonatal and Developing Lung Abstract Award

Bourke, Jane (Recipient), 2016

Prize: Prize (including medals and awards)

Fellow of the American Thoracic Society (ATSF)

Bourke, Jane (Recipient), 29 Nov 2019

Prize: Election to learned society

File

Vice Chancellor's Diversity and Inclusion Award

Bourke, Jane (Recipient), 2017

Prize: Other distinction

File

Press / Media

The Monash Panel Pledge

Jane Bourke

9/10/19

1 Media contribution

Press/Media: Public Engagement Activities

ABC radio: Silicosis

Jane Bourke

17/09/1920/09/19

2 Media contributions

Press/Media: Expert Comment

Monash Lens - Silicosis: Hormone hope in fight against deadly disease

Jane Bourke

2/08/19

1 item of Media coverage

Press/Media: Article/Feature

American Thoracic Society - invited research profile

Jane Bourke

26/12/18

1 item of Media coverage

Press/Media: Profile/Interview