• Ground floor, 19 Innovation walk, Monash university

    3800 Clayton campus

    Australia

19962019
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Research Output 1996 2019

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2019

A microfluidic-SERSplatform for isolation and immuno-phenotyping of antigen specific T-cells

Dey, S., Vaidyanathan, R., Reza, K. K., Wang, J., Wang, Y., Nel, H. J., Law, S. C., Tyler, J., Rossjohn, J., Reid, H. H., Ibn Sina, A. A., Thomas, R. & Trau, M., 1 Apr 2019, In : Sensors and Actuators B: Chemical. 284, p. 281-288 8 p.

Research output: Contribution to journalArticleResearchpeer-review

A plasmid-encoded peptide from Staphylococcus aureus induces anti-myeloperoxidase nephritogenic autoimmunity

Ooi, J. D., Jiang, J-H., Eggenhuizen, P. J., Chua, L. L., van Timmeren, M., Loh, K. L., O’Sullivan, K. M., Gan, P. Y., Zhong, Y., Tsyganov, K., Shochet, L. R., Ryan, J., Stegeman, C. A., Fugger, L., Reid, H. H., Rossjohn, J., Heeringa, P., Holdsworth, S. R., Peleg, A. Y. & Kitching, A. R., 29 Jul 2019, In : Nature Communications. 10, 1, 14 p., 3392.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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A subset of HLA-DP molecules serve as ligands for the natural cytotoxicity receptor NKp44

Niehrs, A., Garcia-Beltran, W. F., Norman, P. J., Watson, G. M., Hölzemer, A., Chapel, A., Richert, L., Pommerening-Röser, A., Körner, C., Ozawa, M., Martrus, G., Rossjohn, J., Lee, J-H., Berry, R., Carrington, M. & Altfeld, M., 29 Jul 2019, In : Nature Immunology. 20, 9, p. 1129-1137 9 p.

Research output: Contribution to journalArticleResearchpeer-review

A T-cell receptor escape channel allows broad T-cell response to CD1b and membrane phospholipids

Shahine, A., Reinink, P., Reijneveld, J. F., Gras, S., Holzheimer, M., Cheng, T. Y., Minnaard, A. J., Altman, J. D., Lenz, S., Prandi, J., Kubler-Kielb, J., Moody, D. B., Rossjohn, J. & Van Rhijn, I., 4 Jan 2019, In : Nature Communications. 10, 1, 12 p., 56.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Chronic Inflammation Permanently Reshapes Tissue-Resident Immunity in Celiac Disease

Mayassi, T., Ladell, K., Gudjonson, H., McLaren, J. E., Shaw, D. G., Tran, M. T., Rokicka, J. J., Lawrence, I., Grenier, J. C., van Unen, V., Ciszewski, C., Dimaano, M., Sayegh, H. E., Kumar, V., Wijmenga, C., Green, P. H. R., Gokhale, R., Jericho, H., Semrad, C. E., Guandalini, S. & 7 others, Dinner, A. R., Kupfer, S. S., Reid, H. H., Barreiro, L. B., Rossjohn, J., Price, D. A. & Jabri, B., 21 Feb 2019, In : Cell. 176, 5, p. 967-981 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Discriminative T-cell receptor recognition of highly homologous HLA-DQ2– bound gluten epitopes

Dahal-Koirala, S., Ciacchi, L., Petersen, J., Risnes, L. F., Neumann, R. S., Christophersen, A., Lundin, K. E. A., Reid, H. H., Qiao, S. W., Rossjohn, J. & Sollid, L. M., 18 Jan 2019, In : Journal of Biological Chemistry. 294, 3, p. 941-952 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Downregulation of MHC Class I Expression by Influenza A and B Viruses

Koutsakos, M., McWilliam, H. E. G., Aktepe, T. E., Fritzlar, S., Illing, P. T., Mifsud, N. A., Purcell, A. W., Rockman, S., Reading, P. C., Vivian, J. P., Rossjohn, J., Brooks, A. G., Mackenzie, J. M., Mintern, J. D., Villadangos, J. A., Nguyen, T. H. O. & Kedzierska, K., 29 May 2019, In : Frontiers in Immunology. 10, 12 p., 1158.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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H1N1 hemagglutinin-specific HLA-DQ6-restricted CD4+ T cells can be readily detected in narcolepsy type 1 patients and healthy controls

Schinkelshoek, M. S., Fronczek, R., Kooy-Winkelaar, E. M. C., Petersen, J., Reid, H. H., van der Heide, A., Drijfhout, J. W., Rossjohn, J., Lammers, G. J. & Koning, F., 15 Jul 2019, In : Journal of Neuroimmunology. 332, p. 167-175 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Human CD8 + T cell cross-reactivity across influenza A, B and C viruses

Koutsakos, M., Illing, P. T., Nguyen, T. H. O., Mifsud, N. A., Crawford, J. C., Rizzetto, S., Eltahla, A. A., Clemens, E. B., Sant, S., Chua, B. Y., Wong, C. Y., Allen, E. K., Teng, D., Dash, P., Boyd, D. F., Grzelak, L., Zeng, W., Hurt, A. C., Barr, I., Rockman, S. & 17 others, Jackson, D. C., Kotsimbos, T. C., Cheng, A. C., Richards, M., Westall, G. P., Loudovaris, T., Mannering, S. I., Elliott, M., Tangye, S. G., Wakim, L. M., Rossjohn, J., Vijaykrishna, D., Luciani, F., Thomas, P. G., Gras, S., Purcell, A. W. & Kedzierska, K., 18 Feb 2019, In : Nature Immunology. 20, p. 613-625 15 p.

Research output: Contribution to journalArticleResearchpeer-review

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PD-L1– and calcitriol-dependent liposomal antigen-specific regulation of systemic inflammatory autoimmune disease

Galea, R., Nel, H. J., Talekar, M., Liu, X., Ooi, J. D., Huynh, M., Hadjigol, S., Robson, K. J., Ting, Y. T., Cole, S., Cochlin, K., Hitchcock, S., Zeng, B., Yekollu, S., Boks, M., Goh, N., Roberts, H., Rossjohn, J., Reid, H. H., Boyd, B. J. & 7 others, Malaviya, R., Shealy, D. J., Baker, D. G., Madakamutil, L., Richard Kitching, A., O’Sullivan, B. J. & Thomas, R., 19 Sep 2019, In : JCI Insight. 4, 18, 21 p., e126025.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Structural Basis for CD96 Immune Receptor Recognition of Nectin-like Protein-5, CD155

Deuss, F. A., Watson, G. M., Fu, Z., Rossjohn, J. & Berry, R., 5 Feb 2019, In : Structure. 27, 2, p. 219-228 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Structural basis for the recognition of nectin-like protein-5 by the human-activating immune receptor, DNAM-1

Deuss, F. A., Watson, G. M., Goodall, K. J., Leece, I., Chatterjee, S., Fu, Z., Thaysen-Andersen, M., Andrews, D. M., Rossjohn, J. & Berry, R., 16 Aug 2019, In : Journal of Biological Chemistry. 294, 33, p. 12534-12546 13 p.

Research output: Contribution to journalArticleResearchpeer-review

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The early proximal TCR signalosome specifies thymic selection outcome through a quantitative protein interaction network

Neier, S. C., Ferrer, A., Wilton, K. M., Smith, S. E. P., Kelcher, A. M. H., Pavelko, K. D., Canfield, J. M., Davis, T. R., Stiles, R. J., Chen, Z., McCluskey, J., Burrows, S. R., Rossjohn, J., Hebrink, D. M., Carmona, E. M., Limper, A. H., Kappes, D. J., Wettstein, P. J., Johnson, A. J., Pease, L. R. & 4 others, Daniels, M. A., Neuhauser, C., Gil, D. & Schrum, A. G., 15 Feb 2019, In : Science Immunology. 4, 32, 15 p., eaal2201.

Research output: Contribution to journalArticleResearchpeer-review

2018

An overview on the identification of MAIT cell antigens

Kjer-Nielsen, L., Corbett, A. J., Chen, Z., Liu, L., Mak, J. Y., Godfrey, D. I., Rossjohn, J., Fairlie, D. P., Mccluskey, J. & Eckle, S. B., Jul 2018, In : Immunology and Cell Biology. 96, 6, p. 573-587 15 p.

Research output: Contribution to journalArticleResearchpeer-review

A subset of HLA-I peptides are not genomically templated: Evidence for cis- and trans-spliced peptide ligands

Faridi, P., Li, C., Ramarathinam, S. H., Vivian, J. P., Illing, P. T., Mifsud, N. A., Ayala, R., Song, J., Gearing, L. J., Hertzog, P. J., Ternette, N., Rossjohn, J., Croft, N. P. & Purcell, A. W., 12 Oct 2018, In : Science Immunology. 3, 28, 12 p., eaar3947.

Research output: Contribution to journalArticleResearchpeer-review

Broad CD8+ T cell cross-recognition of distinct influenza A strains in humans

Grant, E. J., Josephs, T. M., Loh, L., Clemens, E. B., Sant, S., Bharadwaj, M., Chen, W., Rossjohn, J., Gras, S. & Kedzierska, K., 21 Dec 2018, In : Nature Communications. 9, 1, 16 p., 5427.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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CD4+ T cell-mediated HLA class II cross-restriction in HIV controllers

Galperin, M., Farenc, C., Mukhopadhyay, M., Jayasinghe, D., Decroos, A., Benati, D., Tan, L. L., Ciacchi, L., Reid, H. H., Rossjohn, J., Chakrabarti, L. & Gras, S., 8 Jun 2018, In : Science Immunology. 3, 24, 13 p., eaat0687.

Research output: Contribution to journalArticleResearchpeer-review

Differing roles of CD1d2 and CD1d1 proteins in type I natural killer T cell development and function

Sundararaj, S., Zhang, J., Krovi, S. H., Bedel, R., Tuttle, K. D., Veerapen, N., Besra, G. S., Khandokar, Y., Praveena, T., Le Nours, J., Matsuda, J. L., Rossjohn, J. & Gapin, L., 6 Feb 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 6, p. E1204-E1213 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Divergent T-cell receptor recognition modes of a HLA-I restricted extended tumour-associated peptide

Chan, K. F., Gully, B. S., Gras, S., Beringer, D. X., Kjer-Nielsen, L., Cebon, J., McCluskey, J., Chen, W. & Rossjohn, J., 1 Dec 2018, In : Nature Communications. 9, 1, 13 p., 1026.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Dual Modifications of α-Galactosylceramide Synergize to Promote Activation of Human Invariant Natural Killer T Cells and Stimulate Anti-tumor Immunity

Chennamadhavuni, D., Saavedra-Avila, N. A., Carreño, L. J., Guberman-Pfeffer, M. J., Arora, P., Yongqing, T., Koay, H. F., Godfrey, D. I., Keshipeddy, S., Richardson, S. K., Sundararaj, S., Lo, J. H., Wen, X., Gascón, J. A., Yuan, W., Rossjohn, J., Le Nours, J., Porcelli, S. A. & Howell, A. R., 17 May 2018, In : Cell Chemical Biology. 25, 5, p. 571-584 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Flow cytometric clinical immunomonitoring using peptide-MHC class II tetramers: Optimization of methods and protocol development

Jansen, D. T. S. L., Ramnoruth, N., Loh, K. L., Rossjohn, J., Reid, H. H., Nel, H. J. & Thomas, R., 22 Jan 2018, In : Frontiers in Immunology. 9, 10 p., 8.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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HLA-B57 micropolymorphism defines the sequence and conformational breadth of the immunopeptidome

Illing, P. T., Pymm, P., Croft, N. P., Hilton, H. G., Jojic, V., Han, A. S., Mendoza, J. L., Mifsud, N. A., Dudek, N. L., McCluskey, J., Parham, P., Rossjohn, J., Vivian, J. P. & Purcell, A. W., 8 Nov 2018, In : Nature Communications. 9, 1, 13 p., 4693.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Identification of native and posttranslationally modified HLA-B*57:01- restricted HIV envelope derived epitopes using immunoproteomics

Ramarathinam, S. H., Gras, S., Alcantara, S., Yeung, A. W. S., Mifsud, N. A., Sonza, S., Illing, P., Glaros, E. N., Center, R. J., Thomas, S. R., Kent, S. J., Ternette, N., Purcell, D. F. J., Rossjohn, J. & Purcell, A. W., Jun 2018, In : Proteomics. 18, 12, 11 p., 1700253.

Research output: Contribution to journalArticleResearchpeer-review

Inability to detect cross-reactive memory T cells challenges the frequency of heterologous immunity among common viruses

Rowntree, L. C., Nguyen, T. H. O., Halim, H., Purcell, A. W., Rossjohn, J., Gras, S., Kotsimbos, T. C. & Mifsud, N. A., 15 Jun 2018, In : Journal of Immunology. 200, 12, p. 3993-4003 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Killer cell immunoglobulin-like receptor 3DL1 variation modifies HLA-B*57 protection against HIV-1

Martin, M. P., Naranbhai, V., Shea, P. R., Qi, Y., Ramsuran, V., Vince, N., Gao, X., Thomas, R., Brumme, Z. L., Carlson, J. M., Wolinsky, S. M., Goedert, J. J., Walker, B. D., Segal, F. P., Deeks, S. G., Haas, D. W., Migueles, S. A., Connors, M., Michael, N., Fellay, J. & 12 others, Gostick, E., Llewellyn-Lacey, S., Price, D. A., Lafont, B. A., Pymm, P., Saunders, P. M., Widjaja, J., Wong, S. C., Vivian, J. P., Rossjohn, J., Brooks, A. G. & Carrington, M., 1 May 2018, In : Journal of Clinical Investigation. 128, 5, p. 1903-1912 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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MAIT cells protect against pulmonary Legionella longbeachae infection

Wang, H., D’Souza, C., Lim, X. Y., Kostenko, L., Pediongco, T. J., Eckle, S. B. G., Meehan, B. S., Shi, M., Wang, N., Li, S., Liu, L., Mak, J. Y. W., Fairlie, D. P., Iwakura, Y., Gunnersen, J. M., Stent, A. W., Godfrey, D. I., Rossjohn, J., Westall, G. P., Kjer-Nielsen, L. & 5 others, Strugnell, R. A., McCluskey, J., Corbett, A. J., Hinks, T. S. C. & Chen, Z., 1 Dec 2018, In : Nature Communications. 9, 1, 15 p., 3350.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Mucosal-associated invariant T cell receptor recognition of small molecules presented by MR1

Awad, W., Le Nours, J., Kjer-Nielsen, L., Mccluskey, J. & Rossjohn, J., Jul 2018, In : Immunology and Cell Biology. 96, 6, p. 588-597 10 p.

Research output: Contribution to journalArticleOtherpeer-review

Mucosal-associated invariant T cells augment immunopathology and gastritis in chronic helicobacter pylori infection

D'Souza, C., Pediongco, T., Wang, H., Scheerlinck, J. P. Y., Kostenko, L., Esterbauer, R., Stent, A. W., Eckle, S. B. G., Meehan, B. S., Strugnell, R. A., Cao, H., Liu, L., Mak, J. Y. W., Lovrecz, G., Lu, L., Fairlie, D. P., Rossjohn, J., McCluskey, J., Every, A. L., Chen, Z. & 1 others, Corbett, A. J., 1 Mar 2018, In : Journal of Immunology. 200, 5, p. 1901-1916 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Peptide mimic for influenza vaccination using nonnatural combinatorial chemistry

Miles, J. J., Tan, M. P., Dolton, G., Edwards, E. S. J., Galloway, S. A. E., Laugel, B., Clement, M., Makinde, J., Ladell, K., Matthews, K. K., Watkins, T. S., Tungatt, K., Wong, Y., Lee, H. S., Clark, R. J., Pentier, J. M., Attaf, M., Lissina, A., Ager, A., Gallimore, A. & 7 others, Rizkallah, P. J., Gras, S., Rossjohn, J., Burrows, S. R., Cole, D. K., Price, D. A. & Sewell, A. K., 2 Apr 2018, In : Journal of Clinical Investigation. 128, 4, p. 1569-1580 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Recipient mucosal-associated invariant T cells control GVHD within the colon

Varelias, A., Bunting, M. D., Ormerod, K. L., Koyama, M., Olver, S. D., Straube, J., Kuns, R. D., Robb, R. J., Henden, A. S., Cooper, L., Lachner, N., Gartlan, K. H., Lantz, O., Kjer-Nielsen, L., Mak, J. Y. W., Fairlie, D. P., Clouston, A. D., McCluskey, J., Rossjohn, J., Lane, S. W. & 2 others, Hugenholtz, P. & Hill, G. R., 1 May 2018, In : Journal of Clinical Investigation. 128, 5, p. 1919-1936 18 p.

Research output: Contribution to journalArticleResearchpeer-review

Recognition of host Clr-b by the inhibitory NKR-P1B receptor provides a basis for missing-self recognition

Balaji, G. R., Aguilar, O. A., Tanaka, M., Shingu-Vazquez, M. A., Fu, Z., Gully, B. S., Lanier, L. L., Carlyle, J. R., Rossjohn, J. & Berry, R., 5 Nov 2018, In : Nature Communications. 9, 1, 12 p., 4623.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Single-cell approach to influenza-specific CD8+ T cell receptor repertoires across different age groups, tissues, and following influenza virus infection

Sant, S., Grzelak, L., Wang, Z., Pizzolla, A., Koutsakos, M., Crowe, J., Loudovaris, T., Mannering, S. I., Westall, G. P., Wakim, L. M., Rossjohn, J., Gras, S., Richards, M., Xu, J., Thomas, P. G., Loh, L., Nguyen, T. H. O. & Kedzierska, K., 27 Jun 2018, In : Frontiers in Immunology. 9, 18 p., 1453.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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T cell autoreactivity directed toward CD1c itself rather than toward carried self lipids

Wun, K. S., Reijneveld, J. F., Cheng, T. Y., Ladell, K., Uldrich, A. P., Le Nours, J., Miners, K. L., McLaren, J. E., Grant, E. J., Haigh, O. L., Watkins, T. S., Suliman, S., Iwany, S., Jimenez, J., Calderon, R., Tamara, K. L., Leon, S. R., Murray, M. B., Mayfield, J. A., Altman, J. D. & 8 others, Purcell, A. W., Miles, J. J., Godfrey, D. I., Gras, S., Price, D. A., Van Rhijn, I., Moody, D. B. & Rossjohn, J., 1 Apr 2018, In : Nature Immunology. 19, 4, p. 397-406 10 p.

Research output: Contribution to journalArticleResearchpeer-review

The interplay between citrullination and HLA-DRB1 polymorphism in shaping peptide binding hierarchies in rheumatoid arthritis

Ting, Y. T., Petersen, J., Ramarathinam, S. H., Scally, S. W., Loh, K. L., Thomas, R., Suri, A., Baker, D. G., Purcell, A. W., Reid, H. H. & Rossjohn, J., 2 Mar 2018, In : Journal of Biological Chemistry. 293, 9, p. 3236-3251 16 p.

Research output: Contribution to journalArticleResearchpeer-review

2017

A conserved energetic footprint underpins recognition of human leukocyte antigen-E by two distinct αβ T cell receptors

Sullivan, L. C., Walpole, N. G., Farenc, C., Pietra, G., Sum, M. J. W., Clements, C. S., Lee, E. J., Beddoe, T., Falco, M., Mingari, M. C., Moretta, L., Gras, S., Rossjohn, J. & Brooks, A. G., 22 Dec 2017, In : Journal of Biological Chemistry. 292, 51, p. 21149-21158 10 p.

Research output: Contribution to journalArticleResearchpeer-review

A hot spot on interferon α/β receptor subunit 1 (IFNAR1) underpins its interaction with interferon-β and dictates signaling

de Weerd, N. A., Matthews, A. Y., Pattie, P. R., Bourke, N. M., Lim, S. S., Vivian, J. P., Rossjohn, J. & Hertzog, P. J., 5 May 2017, In : Journal of Biological Chemistry. 292, 18, p. 7554-7565 13 p.

Research output: Contribution to journalArticleResearchpeer-review

A molecular basis of human T cell receptor autoreactivity toward self-phospholipids

Shahine, A., Van Rhijn, I., Cheng, T-Y., Iwany, S., Gras, S., Moody, D. B. & Rossjohn, J., 20 Oct 2017, In : Science Immunology. 2, 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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A T Cell Receptor Locus Harbors a Malaria-Specific Immune Response Gene

Van Braeckel-Budimir, N., Gras, S., Ladell, K., Josephs, T. M., Pewe, L., Urban, S. L., Miners, K. L., Farenc, C., Price, D. A., Rossjohn, J. & Harty, J. T., 21 Nov 2017, In : Immunity. 47, 5, p. 835-847 14 p.

Research output: Contribution to journalArticleResearchpeer-review

A Viral Immunoevasin Controls Innate Immunity by Targeting the Prototypical Natural Killer Cell Receptor Family

Aguilar, O. A., Berry, R., Rahim, M. M. A., Reichel, J. J., Popović, B., Tanaka, M., Fu, Z., Balaji, G. R., Lau, T. N. H., Tu, M. M., Kirkham, C. L., Mahmoud, A. B., Mesci, A., Krmpotić, A., Allan, D. S. J., Makrigiannis, A. P., Jonjić, S., Rossjohn, J. & Carlyle, J. R., 23 Mar 2017, In : Cell. 169, 1, p. 58-71 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Circulating gluten-specific FOXP3+CD39+ regulatory T cells have impaired suppressive function in patients with celiac disease

Cook, L., Munier, C. M. L., Seddiki, N., van Bockel, D. J., Ontiveros, N., Hardy, M. Y., Gillies, J. K., Levings, M. K., Reid, H. H., Petersen, J., Rossjohn, J., Anderson, R. P., Zaunders, J., Tye-Din, J. A. & Kelleher, A. D., Dec 2017, In : Journal of Allergy and Clinical Immunology. 140, 6, p. 1592-1603 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Cytotoxic and regulatory roles of mucosal-associated invariant T cells in type 1 diabetes

Rouxel, O., Da Silva, J., Beaudoin, L., Nel, I., Tard, C., Cagninacci, L., Kiaf, B., Oshima, M., Diedisheim, M., Salou, M., Corbett, A., Rossjohn, J., McCluskey, J., Scharfmann, R., Battaglia, M., Polak, M., Lantz, O., Beltrand, J. & Lehuen, A., 16 Nov 2017, In : Nature Immunology. 18, 12, p. 1321-1331 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells

Ooi, J. D., Petersen, J., Tan, Y. H., Huynh, M., Willett, Z. J., Ramarathinam, S. H., Eggenhuizen, P. J., Loh, K. L., Watson, K. A., Gan, P. Y., Alikhan, M. A., Dudek, N. L., Handel, A., Hudson, B. G., Fugger, L., Power, D. A., Holt, S. G., Coates, P. T., Gregersen, J. W., Purcell, A. W. & 5 others, Holdsworth, S. R., La Gruta, N. L., Reid, H. H., Rossjohn, J. & Kitching, A. R., 11 May 2017, In : Nature. 545, 7653, p. 243-247 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Drugs and drug-like molecules can modulate the function of mucosal-associated invariant T cells

Keller, A. N., Eckle, S. B. G., Xu, W., Liu, L., Hughes, V. A., Mak, J. Y. W., Meehan, B. S., Pediongco, T., Birkinshaw, R. W., Chen, Z., Wang, H., D'Souza, C., Kjer-Nielsen, L., Gherardin, N. A., Godfrey, D. I., Kostenko, L., Corbett, A. J., Purcell, A. W., Fairlie, D. P., McCluskey, J. & 1 others, Rossjohn, J., Apr 2017, In : Nature Immunology. 18, 4, p. 402-411 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Germline bias dictates cross-serotype reactivity in a common dengue-virus-specific CD8 + T cell response

Culshaw, A., Ladell, K., Gras, S., McLaren, J. E., Miners, K. L., Farenc, C., Van Den Heuvel, H., Gostick, E., Dejnirattisai, W., Wangteeraprasert, A., Duangchinda, T., Chotiyarnwong, P., Limpitikul, W., Vasanawathana, S., Malasit, P., Dong, T., Rossjohn, J., Mongkolsapaya, J., Price, D. A. & Screaton, G. R., 18 Oct 2017, In : Nature Immunology. 18, 11, p. 1228-1237 10 p.

Research output: Contribution to journalArticleResearchpeer-review

MAIT cells launch a rapid, robust and distinct hyperinflammatory response to bacterial superantigens and quickly acquire an anergic phenotype that impedes their cognate antimicrobial function: Defining a novel mechanism of superantigen-induced immunopathology and immunosuppression

Shaler, C. R., Choi, J. J., Rudak, P. T., Memarnejadian, A., Szabo, P. A., Tun-Abraham, M. E., Rossjohn, J., Corbett, A. J., McCluskey, J., McCormick, J. K., Lantz, O., Hernandez-Alejandro, R. & Haeryfar, S. M. M., 20 Jun 2017, In : PLoS Biology. 15, 6, 35 p., e2001930.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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MHC-I peptides get out of the groove and enable a novel mechanism of HIV-1 escape

Pymm, P., Illing, P. T., Ramarathinam, S. H., O'Connor, G. M., Hughes, V. A., Hitchen, C., Price, D. A., Ho, B. K., McVicar, D. W., Brooks, A. G., Purcell, A. W., Rossjohn, J. & Vivian, J. P., Apr 2017, In : Nature Structural and Molecular Biology. 24, 4, p. 387-394 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Molecular basis for increased susceptibility of Indigenous North Americans to seropositive rheumatoid arthritis

Scally, S. W., Law, S. C., Ting, Y. T., Heemst, J. V., Sokolove, J., Deutsch, A. J., Bridie Clemens, E., Moustakas, A. K., Papadopoulos, G. K., Woude, D. V. D., Smolik, I., Hitchon, C. A., Robinson, D. B., Ferucci, E. D., Bernstein, C. N., Meng, X., Anaparti, V., Huizinga, T., Kedzierska, K., Reid, H. H. & 5 others, Raychaudhuri, S., Toes, R. E., Rossjohn, J., El-Gabalawy, H. & Thomas, R., 1 Nov 2017, In : Annals of the Rheumatic Diseases. 76, 11, p. 1915-1923 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Mucosal-associated invariant T-cell activation and accumulation after in vivo infection depends on microbial riboflavin synthesis and co-stimulatory signals

Chen, Z., Wang, H., D'Souza, C., Sun, S., Kostenko, L., Eckle, SBG., Meehan, BS., Jackson, DC., Strugnell, RA., Cao, H., Wang, N., Fairlie, DP., Liu, L., Godfrey, DI., Rossjohn, J., McCluskey, J. & Corbett, AJ., 1 Jan 2017, In : Mucosal Immunology. 10, 1, p. 58-68 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Recognition of nectin-2 by the natural killer cell receptor T cell immunoglobulin and ITIM domain (TIGIT)

Deuss, F. A., Gully, B. S., Rossjohn, J. & Berry, R., 7 Jul 2017, In : Journal of Biological Chemistry. 292, 27, p. 11413-11422 10 p.

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Stabilizing short-lived Schiff base derivatives of 5-aminouracils that activate mucosal-associated invariant T cells

Mak, J. Y. W., Xu, W., Reid, R. C., Corbett, A. J., Meehan, B. S., Wang, H., Chen, Z., Rossjohn, J., McCluskey, J., Liu, L. & Fairlie, D. P., 8 Mar 2017, In : Nature Communications. 8, 13 p., 14599.

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