Projects per year
Personal profile
Biography
Professor D. James Cooper AO
BMBS MD FRACP FCICM FAHMS
Jamie Cooper is Sir John Monash Distinguished Professor in the School of Public Health and Preventive Medicine (SPHPM) at Monash University, and Senior Specialist in Intensive Care at The Alfred Hospital, Melbourne. In 2017, he was awarded an Officer of the Order of Australia (AO) for distinguished service to intensive care medicine in the field of traumatic brain injury as a clinician, and to medical education as an academic, researcher and author. In 2021, Professors Jamie Cooper and Rinaldo Bellomo were jointly awarded the Research Australia GSK Award for Research Excellence (ARE) in recognition of their global leadership and innovative research in critical care medicine that has helped transform approaches to the treatment of critically ill patients worldwide. The GSK ARE is one of the most prestigious awards available to the Australian medical research community. Prof Cooper is a National Health and Medical Research Council (NHMRC) Practitioner Fellow, full Professor of Intensive Care Medicine at Monash University and Hon. Professorial Fellow in the Critical Care and Trauma Division at The George Institute for Global Health, University of Sydney. He has >400 publications including 18 in New England Journal of Medicine (NEJM), The Lancet, and Journal of the American Medical Association (JAMA). He has been a Principal or Co-investigator on peer reviewed research grants exceeding $88M including 44 NHMRC/MRFF grants. Research foci include randomised clinical trials in traumatic brain injury (TBI), sepsis, acute lung injury, resuscitation fluids, and blood transfusion.
He has published three landmark trials including the DECRA trial (CIA NHMRC#314502), which demonstrated unexpectedly inferior long-term outcomes for an increasingly popular neurosurgical intervention (early decompressive craniectomy) that was opposite to apparent short-term benefits, and has initiated international TBI practice review. The trial results were fast tracked for NEJM publication (Cooper DJ, et al. 2011) and were editorialised in the Lancet as “one of the most important clinical trials of a therapy for severe TBI ever conducted”. The trial results have been a watershed in changing current practice and have proved invaluable from both an individual patient and community perspective. This has been incorporated into the international Brain Trauma Foundation practice guidelines. Using alternative therapies will improve TBI patient outcomes and substantially reduce health care spending on lifetime care of severe disability survivors. DECRA was included in Yale University’s 50 most important papers of all time “that shaped the current clinical practice of neurology” and was also included in the “50 of the most important studies in Critical Care Medicine” by Harvard University and Oxford University Press.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- Acute lung injury
- Blood transfusion
- Decompressive craniectomy
- Resuscitation fluids
- Sepsis
- Traumatic brain injury
Network
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SODA-BIC: SODA-BIC: Sodium Bicarbonate For Decompensated Metabolic Acidosis in the Intensive Care Unit, A Multicentre, Randomised, Double-Blind Clinical Trial
Serpa Neto, A., Bellomo, R., Peake, S., Bailey, M., Cooper, J., Udy, A., Young, P., Secombe, P., Higgins, L., See, E. J., Hodgson, C., Taylor, P., Campbell, L. T., Fujii, T., Young, M. & Maeda, M.
1/07/22 → 30/06/27
Project: Research
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Fibrinogen Early In Severe Trauma StudY II (FEISTY II)
McQuilten, Z., Winearls, J., Cooper, J., Reade, M., French, C. J., Presneill, J., Higgins, L., Balogh, Z., Heritier, S. & Wood, E.
1/02/22 → 31/01/27
Project: Research
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A Centre for Research Excellence to Transform Outcomes of Critically Ill Patients in ICU (CRE-ICU)
Hodgson, C., Cooper, J., Fraser, J. F., Peake, S., Bellomo, R., Macdonald, P. S., Bernard, S., Bailey, M., McGiffin, D. & Higgins, L.
1/11/21 → 31/10/26
Project: Research
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An informatics approach to predict outcomes and monitor intervention efficacy following moderate to severe traumatic brain injury
Fitzgerald, M., Gabbe, B., Lannin, N., Vallmuur, K., Curtis, K., Harrison, J., Young, J. T., Menon, D. K., Cullen, J. C., Armstrong, E., Eades, S., Cameron, P., Cooper, J., Fitzgerald, M., Balogh, Z., Fatovich, D., Honeybul, S., Jeffree, R. L., McNamara, R., Mitchell, G. J., Delaney, A., Reade, M. C., Wells, A., Williams, J., Ponsford, J., McDonald, S., Kendall, E., Ownsworth , T., Simpson, G., Togher, L., Hassett, L., Fleming, J., Williams, G. P., Collins-Praino, L. E., Reeder, S., Mobbs, R., Vickers, J., Anderson, V., Barlow, K., Holland, A. J. A., Scheinberg, A., Semple, B., Parizel, P. M., O'Brien, T., Law, M., Rose, S. E., Varma, D., Nasrallah, F., Shultz, S., Hellewell, S., Bosio, E., King , K., Parr, M., Udy, A., Hill, A. F., Olver, J., Teague, W. J., Egan, G., Fisher, M., York, L., Bynevelt, M., Maas, A. I., O'Reilly, G., McDonald, S., Capell, J., Gilroy, J., Walsham, J., Newcombe, V., Geraghty, T. J., Joyce, C. J., Rosenfeld, J., Elcock, M., Ross, J., Bragge, P., Meka, S., Chai, K., Cowen, G., Hasseler, L., Ercole, A., Wagland , J., Alexander, T., Babl, F. E., Bidargaddi, N., Mahoney, A. J., Wright, D., Crowe, L. M., Robinson, S., Rushworth, N., Hansen, M., Ellis, D., Zeeman, H., Francis, R., Whiley, L. & Reid, C.
1/07/21 → 30/06/23
Project: Research
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PRECISION-TBI: PRECISION-TBI – Promoting evidence-based, data driven care for critically ill moderate-to-severe TBI patients
Udy, A., Cooper, J., Jeffree, L., Bellomo, R., Nichol, A., O'Brien, T., Bellapart, J., Menon, D. K., McNamara, R., Fitzgerald, M., Togher, L., Delaney, A., Anstey, J. R., Honeybul, S., Hunn, M., Reddi, B. A. J., Adamides, A. A., Wells, A. & Lewis, P.
1/06/21 → 31/05/25
Project: Research
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Erratum: Correction: High arterial oxygen levels and supplemental oxygen administration in traumatic brain injury: insights from CENTER-TBI and OzENTER-TBI (Intensive care medicine (2022) 48 12 (1709-1725))
Rezoagli, E., Petrosino, M., Rebora, P., Menon, D. K., Mondello, S., Cooper, D. J., Maas, A. I. R., Wiegers, E. J. A., Galimberti, S., Citerio, G. & on behalf of CENTER-TBI, OzENTER-TBI Participants and Investigators, Feb 2023, In: Intensive Care Medicine. 49, 2, p. 269-272 4 p.Research output: Contribution to journal › Comment / Debate › Other › peer-review
Open Access -
Systematic reviews and consensus definitions for the Standardised Endpoints in Perioperative Medicine (StEP) initiative: mortality, morbidity, and organ failure
Jackson, A. I. R., Boney, O., Pearse, R. M., Kurz, A., Cooper, D. J., van Klei, W. A., Cabrini, L., Miller, T. E., Moonesinghe, R., Myles, P. S., Grocott, M. & for The StEP-COMPACGroup, Apr 2023, In: British Journal of Anaesthesia. 130, 4, p. 404-411 8 p.Research output: Contribution to journal › Article › Research › peer-review
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AUS-TBI: The Australian Health Informatics Approach to Predict Outcomes and Monitor Intervention Efficacy after Moderate-to-Severe Traumatic Brain Injury
Fitzgerald, M., Ponsford, J. L., Lannin, N., O'Brien, T. J., Cameron, P. A., Cooper, J., Rushworth, N. & Gabbe, B., 2022, In: Neurotrauma Reports. 3, 1, p. 217-223 7 p.Research output: Contribution to journal › Article › Other › peer-review
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Clinical outcomes of Indigenous Australians and New Zealand Māori with metabolic acidosis and acidaemia
Neto, A. S., Fujii, T., Moore, J., Young, P. J., Peake, S., Bailey, M., Hodgson, C., Higgins, A. M., See, E. J., Secombe, P., Russ, V., Campbell, L., Young, M., Maeda, M., Pilcher, D., Cooper, J. & Udy, A., 7 Mar 2022, In: Critical Care and Resuscitation. 24, 1, p. 14-19 6 p.Research output: Contribution to journal › Article › Research › peer-review
1 Citation (Scopus) -
Clustering identifies endotypes of traumatic brain injury in an intensive care cohort: a CENTER-TBI study
Åkerlund, C., Holst, A., Stocchetti, N., Steyerberg, E. W., Menon, D. K., Ercole, A., Nelson, D. W. & the CENTER-TBI investigators and participants, Dec 2022, In: Critical Care. 26, 1, 15 p., 228.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile5 Citations (Scopus)
Prizes
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AMREP (Alfred Research and Medical Education Precinct) Research Prize
Cooper, Jamie (Recipient), Oct 2011
Prize: Prize (including medals and awards)
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AMREP (Alfred Research and Medical Education Precinct) Research Prize
Cooper, Jamie (Recipient), Oct 2016
Prize: Prize (including medals and awards)
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Australian and New Zealand Intensive Care Society’s Clinical Trials Group (CTG) Chair Award
Cooper, Jamie (Recipient), Mar 2014
Prize: Prize (including medals and awards)
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David Sloane Prize to DJ Cooper for the Best Free Paper
Cooper, Jamie (Recipient), Jul 2004
Prize: Prize (including medals and awards)
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Florence Marjorie Hughes Award from the Australian and New Zealand College of Anaesthetists for Best Project in Victoria
Cooper, Jamie (Recipient), Oct 2000
Prize: Prize (including medals and awards)
Press/Media
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Age of blood - Let the claret age a bit. Results of the TRANSFUSE Trial
28/09/17
1 Media contribution
Press/Media: Research
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Meet … Jamie Cooper. Meet our Researchers - Finding the Answers that help ISCRR make a Difference
6/07/15
1 Media contribution
Press/Media: Research
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Research Boost With Monash Partners (Recovery-ICU Seed Funding)
4/04/14
1 Media contribution
Press/Media: Research
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Monash: Delivering Impact: Cool heads may save a lifetime of pain
19/06/13
1 Media contribution
Press/Media: Research
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“A long cycle for life” (the Great Alfred Bike Ride)
13/11/12
1 Media contribution
Press/Media: Expert Comment