Projects per year
Personal profile
Biography
Professor D. James Cooper AO
BMBS MD FRACP FCICM FAHMS
Jamie Cooper is Sir John Monash Distinguished Professor in the School of Public Health and Preventive Medicine (SPHPM) at Monash University, and Senior Specialist in Intensive Care at The Alfred Hospital, Melbourne. In 2017, he was awarded an Officer of the Order of Australia (AO) for distinguished service to intensive care medicine in the field of traumatic brain injury as a clinician, and to medical education as an academic, researcher and author. In 2021, Professors Jamie Cooper and Rinaldo Bellomo were jointly awarded the Research Australia GSK Award for Research Excellence (ARE) in recognition of their global leadership and innovative research in critical care medicine that has helped transform approaches to treatment of critically ill patients worldwide. The GSK ARE is one of the most prestigious awards available to the Australian medical research community. Prof Cooper is a National Health and Medical Research Council (NHMRC) Practitioner Fellow, full Professor of Intensive Care Medicine at Monash University and Hon. Professorial Fellow in the Critical Care and Trauma Division at The George Institute, University of Sydney. He has >400 publications including 18 in New England Journal of Medicine (NEJM), The Lancet, and Journal of the American Medical Association (JAMA). He has been a Principal or Co-investigator on peer reviewed research grants exceeding $85M including 43 NHMRC/MRFF grants. Research foci include randomised clinical trials in traumatic brain injury (TBI), sepsis, acute lung injury, resuscitation fluids, and blood transfusion.
He has published three landmark trials including the DECRA trial (CIA NHMRC#314502), which demonstrated unexpectedly inferior long-term outcomes for an increasingly popular neurosurgical intervention (early decompressive craniectomy) that was opposite to apparent short-term benefits, and has initiated international TBI practice review. The trial results were fast tracked for NEJM publication (Cooper DJ, et al. 2011) and were editorialised in the Lancet as “one of the most important clinical trials of a therapy for severe TBI ever conducted”. The trial results have been a watershed in changing current practice and have proved invaluable from both an individual patient and community perspective. This has been incorporated into the international Brain Trauma Foundation practice guidelines. Using alternative therapies will improve TBI patient outcomes and substantially reduce health care spending on lifetime care of severe disability survivors. DECRA was included in Yale University’s 50 most important papers of all time “that shaped the current clinical practice of neurology” and was also included in the “50 of the most important studies in Critical Care Medicine” by Harvard University and Oxford University Press.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- Acute lung injury
- Blood transfusion
- Decompressive craniectomy
- Resuscitation fluids
- Sepsis
- Traumatic brain injury
Network
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A Centre for Research Excellence to Transform Outcomes of Critically Ill Patients in ICU (CRE-ICU)
Hodgson, C., Cooper, J., Fraser, J. F., Peake, S., Bellomo, R., Macdonald, P. S., Bernard, S., Bailey, M., McGiffin, D. & Higgins, L.
1/11/21 → 31/10/26
Project: Research
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An informatics approach to predict outcomes and monitor intervention efficacy following moderate to severe traumatic brain injury
Fitzgerald, M., Gabbe, B., Lannin, N., Vallmuur, K., Curtis, K., Harrison, J., Young, J. T., Menon, D. K., Cullen, J. C., Armstrong, E., Eades, S., Cameron, P., Cooper, J., Fitzgerald, M., Balogh, Z., Fatovich, D., Honeybul, S., Jeffree, R. L., McNamara, R., Mitchell, G., Delaney, A., Reade, M. C., Wells, A., Williams, J., Ponsford, J., McDonald, S., Kendall, E., Ownsworth , T., Simpson, G., Togher, L., Hassett, L., Fleming, J., Williams, G. P., Collins-Praino, L. E., Reeder, S., Mobbs, R., Vickers, J., Anderson, V., Barlow, K., Holland, A. J. A., Scheinberg, A., Semple, B., Parizel, P. M., O'Brien, T., Law, M., Rose, S. E., Varma, D., Nasrallah, F., Shultz, S., Hellewell, S., Bosio, E., King , K., Parr, M., Udy, A., Hill, A. F., Olver, J., Teague, W. J., Egan, G., Fisher, M., York, L., Bynevelt, M., Maas, A. I., O'Reilly, G., McDonald, S., Capell, J., Gilroy, J., Walsham, J., Newcombe, V., Geraghty, T. J., Joyce, C. J., Rosenfeld, J., Elcock, M., Ross, J., Bragge, P., Meka, S., Chai, K., Cowen, G., Hasseler, L., Ercole, A., Wagland , J., Alexander, T., Babl, F. E., Bidargaddi, N., Mahoney, A. J., Wright, D., Crowe, L. M., Robinson, S., Rushworth, N., Hansen, M., Ellis, D., Zeeman, H., Francis, R., Whiley, L. & Reid, C.
1/07/21 → 30/06/23
Project: Research
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PRECISION-TBI: PRECISION-TBI – Promoting evidence-based, data driven care for critically ill moderate-to-severe TBI patients
Udy, A., Cooper, J., Jeffree, L., Bellomo, R., Nichol, A., O'Brien, T., Bellapart, J., Menon, D. K., McNamara, R., Fitzgerald, M., Togher, L., Delaney, A., Anstey, J. R., Honeybul, S., Hunn, M., Reddi, B. A. J., Adamides, A. A., Wells, A. & Lewis, P.
1/06/21 → 31/05/25
Project: Research
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Brain Oxygen Neuromonitoring In Australia And New Zealand Assessment (BONANZA) Trial
Udy, A., Cooper, J., Nichol, A., Rosenfeld, J., Menon, D. K., Bailey, M., Drummond, K. & Higgins, L.
Department of Health (Australia)
1/12/20 → 30/11/24
Project: Research
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Bone Loss Prevention with Zoledronic Acid or Denosumab in Critically Ill Women – A Randomised Controlled Trial (Bone Zone)
Orford, N., Center, J. R., Nair, P. V., Cooper, J., Hodgson, C., Kotowicz, M., Pasco, J., Bailey, M., Venkatesh, B. & Myburgh, J.
1/06/20 → 30/06/25
Project: Research
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Core Outcome Measures for Perioperative and Anaesthetic Care (COMPAC): a modified Delphi process to develop a core outcome set for trials in perioperative care and anaesthesia
Boney, O., Moonesinghe, S. R., Myles, P. S., Grocott, M. P. W. & the StEP-COMPAC Group, Jan 2022, In: British Journal of Anaesthesia. 128, 1, p. 174-185 12 p.Research output: Contribution to journal › Article › Research › peer-review
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Evaluation of medical emergency team medication management practices in acute hospitals: A multicentre study
Levkovich, B. J., Jones, D. A., Bingham, G., Orosz, J., Dooley, M. J., Cooper, D. J. & Kirkpatrick, C. M., Jan 2022, In: Australian Critical Care. 35, 1, p. 59-65 7 p.Research output: Contribution to journal › Article › Research › peer-review
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Age of red blood cells is not associated with in-hospital mortality in massively transfused patients
Saadah, N. H., Wood, E. M., Bailey, M. J., Cooper, D. J., French, C. J., Haysom, H. E., Sparrow, R. L., Wellard, C. J., McQuilten, Z. K. & on behalf of the Australian and New Zealand Massive Transfusion Registry Steering Committee, Aug 2021, In: The Journal of Trauma and Acute Care Surgery. 91, 2, p. 279-286 8 p.Research output: Contribution to journal › Article › Research › peer-review
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A Post Hoc Analysis of Osmotherapy Use in the Erythropoietin in Traumatic Brain Injury Study-Associations With Acute Kidney Injury and Mortality
Skrifvars, M., Bailey, M., Moore, E. M., Mårtensson, J., French, C., Presneill, J. J., Nichol, A., Little, L., Duranteau, J., Huet, O., Haddad, S., Arabi, Y., McArthur, C., Cooper, D. J., Bendel, S., Bellomo, R. & for the Erythropoietin in Traumatic Brain Injury (EPOTBI) Investigators and the Australian and New Zealand Intensive Care Society (ANZICS) Clinical Trials Group, Apr 2021, In: Critical Care Medicine. 49, 4, p. e394-e403 10 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access3 Citations (Scopus) -
Characteristics, management and outcomes of patients with severe traumatic brain injury in Victoria, Australia compared to United Kingdom and Europe: A comparison between two harmonised prospective cohort studies
Wiegers, E. J. A., Trapani, T., Gabbe, B. J., Gantner, D., Lecky, F., Maas, A. I. R., Menon, D. K., Murray, L., Rosenfeld, J. V., Vallance, S., Lingsma, H. F., Steyerberg, E. W., Cooper, D. J. & the CENTER-TBI and OzENTER-TBI investigators and participants12, Collaboration groups: CENTER-TBI and OzENTER-TBI investigators and participants, Sep 2021, In: Injury. 52, 8, p. 2576-2587 12 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
Prizes
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AMREP (Alfred Research and Medical Education Precinct) Research Prize
Cooper, Jamie (Recipient), Oct 2016
Prize: Prize (including medals and awards)
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AMREP (Alfred Research and Medical Education Precinct) Research Prize
Cooper, Jamie (Recipient), Oct 2011
Prize: Prize (including medals and awards)
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Australian and New Zealand Intensive Care Society’s Clinical Trials Group (CTG) Chair Award
Cooper, Jamie (Recipient), Mar 2014
Prize: Prize (including medals and awards)
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David Sloane Prize to DJ Cooper for the Best Free Paper
Cooper, Jamie (Recipient), Jul 2004
Prize: Prize (including medals and awards)
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Florence Marjorie Hughes Award from the Australian and New Zealand College of Anaesthetists for Best Project in Victoria
Cooper, Jamie (Recipient), Oct 2000
Prize: Prize (including medals and awards)
Press / Media
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Age of blood - Let the claret age a bit. Results of the TRANSFUSE Trial
28/09/17
1 Media contribution
Press/Media: Research
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Meet … Jamie Cooper. Meet our Researchers - Finding the Answers that help ISCRR make a Difference
6/07/15
1 Media contribution
Press/Media: Research
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Research Boost With Monash Partners (Recovery-ICU Seed Funding)
4/04/14
1 Media contribution
Press/Media: Research
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Monash: Delivering Impact: Cool heads may save a lifetime of pain
19/06/13
1 Media contribution
Press/Media: Research
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“A long cycle for life” (the Great Alfred Bike Ride)
13/11/12
1 Media contribution
Press/Media: Expert Comment