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Personal profile

Biography

Professor (DJ) Jamie Cooper AO BMBS MD FRACP FCICM FAHMS 

Professor Cooper is Director of the Australian and New Zealand Intensive Care Research Centre (ANZIC-RC), Monash University; Director of the NHMRC Centre of Research Excellence for Patient Blood Management in Critical Illness and Trauma (Blood-CRE), Monash University; Director of Critical Care Research in the School of Public Health and Preventive Medicine (SPHPM), Monash University; and Head of Research and Deputy Director of the Department of Intensive Care at The Alfred Hospital, Melbourne.  In 2017, he was awarded an Officer of the Order of Australia (AO) for distinguished service to intensive care medicine in the field of traumatic brain injury as a clinician, and to medical education as an academic, researcher and author. He is a National Health and Medical Research Council (NHMRC) Practitioner Fellow, full Professor of Intensive Care Medicine at Monash University and Hon. Professorial Fellow in the Critical Care and Trauma Division at The George Institute, University of Sydney. He has published more than 270 journal papers including 18 in New England Journal of Medicine (NEJM), Lancet, and Journal of the American Medical Association (JAMA). He has been a Principal or Co-investigator on peer reviewed research grants exceeding $58m including 26 NHMRC grants. Research foci include randomised clinical trials in traumatic brain injury (TBI), sepsis, acute lung injury, resuscitation fluids, and blood transfusion.

He has published three landmark trials including the DECRA trial (CIA NHMRC#314502), which demonstrated unexpectedly inferior long-term outcomes for an increasingly popular neurosurgical intervention (early decompressive craniectomy) that was opposite to apparent short-term benefits, and has initiated international TBI practice review. The trial results were fast tracked for NEJM publication (Cooper DJ, et al. 2011) and were editorialised in the Lancet as “one of the most important clinical trials of a therapy for severe TBI ever conducted”. The trial results have been a watershed in changing current practice and have proved invaluable from both an individual patient and community perspective. This was the first Level I evidence in this area and has been incorporated into the international Brain Trauma Foundation practice guidelines. Using alternative therapies will improve TBI patient outcomes and substantially reduce health care spending on lifetime care of severe disability survivors. DECRA was included by Yale University in the top 50 most important Neurological papers of all time.

Keywords

  • Acute lung injury
  • Blood transfusion
  • Decompressive craniectomy
  • Resuscitation fluids
  • Sepsis
  • Traumatic brain injury

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Projects 2000 2024

Research Output 1986 2019

Aspirin in coronary artery surgery: 1-year results of the Aspirin and Tranexamic Acid for Coronary Artery Surgery trial

Myles, P. S., Smith, J. A., Kasza, J., Silbert, B., Jayarajah, M., Painter, T., Cooper, D. J., Marasco, S., McNeil, J., Bussières, J. S., McGuinness, S., Chan, M. T. V., Wallace, S., Forbes, A. & for the ATACAS investigators and the ANZCA Clinical Trials Network, Feb 2019, In : Journal of Thoracic and Cardiovascular Surgery. 157, 2, p. 633-640

Research output: Contribution to journalArticleResearchpeer-review

Erythropoietin in traumatic brain injury associated acute kidney injury: A randomized controlled trial

Skrifvars, M. B., Moore, E., Mårtensson, J., Bailey, M., French, C., Presneill, J., Nichol, A., Little, L., Duranteau, J., Huet, O., Haddad, S., Arabi, Y., McArthur, C., Cooper, D. J., Bellomo, R. & The EPO-TBI Investigators and the ANZICS Clinical Trials Group, Feb 2019, In : Acta Anaesthesiologica Scandinavica. 63, 2, p. 200-207 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Prophylactic Hypothermia for Severe Traumatic Brain Injury-Reply

Cooper, D. J., Nichol, A. D. & McArthur, C., 7 May 2019, In : JAMA. 321, 17, p. 1726 1 p.

Research output: Contribution to journalLetterOtherpeer-review

Quality of life and 1-year survival in patients with early septic shock: long-term follow-up of the Australasian Resuscitation in Sepsis Evaluation Trial

Higgins, A. M., Peake, S. L., Bellomo, R., Cooper, D. J., Delaney, A., Harris, A. H., Howe, B. D., Nichol, A. D., Webb, S. A., Williams, T., on behalf of the Australasian Resuscitation in Sepsis Evaluation (ARISE) Investigators & on behalf of the ANZICS Clinical Trials Group, Jun 2019, In : Critical Care Medicine. 47, 6, p. 765-773 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Tranexamic acid in coronary artery surgery: One-year results of the Aspirin and Tranexamic Acid for Coronary Artery Surgery (ATACAS) trial

Myles, P. S., Smith, J. A., Kasza, J., Silbert, B., Jayarajah, M., Painter, T., Cooper, D. J., Marasco, S., McNeil, J., Bussières, J. S., McGuinness, S., Byrne, K., Chan, M. T. V., Landoni, G., Wallace, S., Forbes, A. & ATACAS investigators and the ANZCA Clinical Trials Network, 1 Feb 2019, In : Journal of Thoracic and Cardiovascular Surgery. 157, 2, p. 644-652 18 p.

Research output: Contribution to journalArticleResearchpeer-review

Prizes

AMREP (Alfred Research and Medical Education Precinct) Research Prize

Jamie Cooper (Recipient), Oct 2016

Prize: Prize (including medals and awards)

AMREP (Alfred Research and Medical Education Precinct) Research Prize

Jamie Cooper (Recipient), Oct 2011

Prize: Prize (including medals and awards)

David Sloane Prize to DJ Cooper for the Best Free Paper

Jamie Cooper (Recipient), Jul 2004

Prize: Prize (including medals and awards)