Projects per year
Personal profile
Biography
Dr James Shaw is the Director of Education and Training in Cardiology at The Alfred, and has held this position since 2014.
He is an interventional cardiologist with a specific interest in the pathophysiology of atherosclerosis both in the coronary and non coronary vascular beds. He is involved in inpatient and outpatient care and partakes in the transthoracic and transoesophageal echocardiogram reporting roster. He is a visiting cardiologist to Sandringham Hospital and to the Bairnsdale Regional health service where he provides outpatient services on a regular basis.
Following completion of his cardiology training in 1997, he undertook a PhD under the supervision of Professor Dart at the Baker Heart and Diabetes Institute and his thesis titled “Mechanisms of Plaque Stability in Coronary Artery Disease” was successfully completed in 2001. Following this he spent 2.5 years at Massachusetts General Hospital and the Brigham and Womens Hospital in Boston completing further clinical and research training in coronary and non coronary interventional work.
In 2004 he returned to Melbourne where he helped establish The Alfred Minimally Invasive Vascular Centre which focuses on endovascular intervention for non coronary atherosclerotic disease. The research interests of Dr Shaw’s group are aligned to the clinical interests and involve active collaboration between various laboratories in the Baker Institute and the clinical department of The Alfred.
He has successfully supervised students in their B Med Science and BSci (hons) projects and is actively involved in registrar supervision and training as well as helping train interventional cardiology fellows many of whom have gone on to gain senior positions.
Dr Shaw has published over 50 peer reviewed manuscripts and has been the Principal Investigator in numerous clinical trials in including the IMPROVE-IT, COMPASS and the ODYSSEY Outcomes studies.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- Pathophysiology
- Cardiology
- Atherosclerosis
Collaborations and top research areas from the last five years
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POSEIDON – Prevalence of systemic inflammation in patients with atherosclerotic cardiovascular disease or heart failure.
Shaw, J. (Primary Chief Investigator (PCI))
22/05/24 → 21/05/26
Project: Research
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A randomized, double -Blind, Placebo-Controlled, Phase 3 study of ISIS 678354 Administered Subcutaneously to patients with Severe Hypertriglyceridemia
Shaw, J. (Primary Chief Investigator (PCI))
10/08/23 → 10/08/25
Project: Research
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HypoPAST: Online psycho-educational training for Hypoglycaemia Prevention, Awareness of Symptoms, and Treatment in adults with type 1 diabetes.
Speight, J. (Primary Chief Investigator (PCI)), Hendrieckx, C. (Chief Investigator (CI)), Skinner, T. C. (Chief Investigator (CI)), Shaw, J. (Chief Investigator (CI)), Mihalopoulos, C. (Chief Investigator (CI)), Zoungas, S. (Chief Investigator (CI)), Versace, V. L. (Chief Investigator (CI)), Wadley, G. (Chief Investigator (CI)), Hagger, V. (Chief Investigator (CI)), Holmes-Truscott, E. (Chief Investigator (CI)), Andrikopoulos, S. (Associate Investigator (AI)), Noonan, G. (Associate Investigator (AI)), Davidson, S. (Associate Investigator (AI)), Black, T. (Associate Investigator (AI)) & Scibilia, R. (Associate Investigator (AI))
29/05/23 → 30/06/25
Project: Research
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Obicetrapib and Cardiovascular Outcomes: A Placebo Controlled, Double-Blind, Randomized Phase 3 Study to Evaluate the Effect of 10 mg Obicetrapib in Participants With Atherosclerotic Cardiovascular Disease (ASCVD) Who are Not Adequately Controlled Despite Maximally Tolerated Lipid Modifying Therapies
Shaw, J. (Primary Chief Investigator (PCI)) & Vandernet, R. (Project Manager)
7/02/23 → 7/02/25
Project: Research
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EMPACT-MI: A streamlined, multicentre, randomised, parallel group, double-blind placebo-controlled superiority trial to evaluate the effect of EMPAgliflozin on hospitalisation for heart failure and mortality in patients with aCuTe Myocardial Infarction.
Shaw, J. (Primary Chief Investigator (PCI))
10/03/22 → 31/12/24
Project: Research
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Clinical Outcomes of Renal Transplant Recipients Undergoing Percutaneous Coronary Intervention
Zheng, W. C., Evans, N., Dinh, D., Bloom, J. E., Brennan, A. L., Ball, J., Lefkovits, J., Shaw, J. A., Reid, C. M., Chan, W. & Stub, D., Jul 2024, In: Heart Lung and Circulation. 33, 7, p. 998-1008 11 p.Research output: Contribution to journal › Article › Research › peer-review
1 Citation (Scopus) -
Ezetimibe Prescribing in the Acute Hospital Setting Following Acute Coronary Syndrome
Jape, D., He, W., Nanayakkara, S. & Shaw, J., Aug 2024, In: Heart Lung and Circulation. 33, Supplement 4, p. S519 1 p., 857.Research output: Contribution to journal › Meeting Abstract › peer-review
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Impact of prehospital opioid dose on angiographic and clinical outcomes in acute coronary syndromes
Fernando, H., Nehme, Z., Dinh, D., Andrew, E., Brennan, A., Shi, W., Bloom, J., Duffy, S. J., Shaw, J., Peter, K., Nadurata, V., Chan, W., Layland, J., Freeman, M., Van Gaal, W., Bernard, S., Lefkovits, J., Liew, D., Stephenson, M. & Smith, K. & 1 others, , Feb 2023, In: Emergency Medicine Journal. 40, 2, p. 101-107 7 p.Research output: Contribution to journal › Article › Research › peer-review
1 Citation (Scopus) -
Sex differences among patients presenting to hospital with out-of-hospital cardiac arrest and shockable rhythm
Ho, F. C. S., Zheng, W. C., Noaman, S., Batchelor, R. J., Wexler, N., Hanson, L., Bloom, J. E., Al-Mukhtar, O., Haji, K., D'Elia, N., Kaye, D., Shaw, J., Yang, Y., French, C., Stub, D., Cox, N. & Chan, W., Apr 2023, In: EMA - Emergency Medicine Australasia. 35, 2, p. 297-305 9 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
UpStreAm doxycycline in ST-eLeVation myocArdial infarction: targetinG infarct hEaling and ModulatIon (SALVAGE-MI trial)
Noaman, S., Neil, C., O’Brien, J., Frenneaux, M., Hare, J., Wang, B., Tai, T. Y., Theuerle, J., Shaw, J., Stub, D., Bloom, J., Walton, A., Duffy, S. J., Peter, K. H., Cox, N., Kaye, D. M., Taylor, A. & Chan, W., 1 Mar 2023, In: European Heart Journal: Acute Cardiovascular Care. 12, 3, p. 143-152 10 p.Research output: Contribution to journal › Article › Research › peer-review
3 Citations (Scopus)