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Personal profile

Biography

Dr McMahon is an Infectious Diseases physician and Head of Clinical Research at the Alfred Hospital and Monash University, and an Infectious Diseases Physician at Monash Medical Centre. He is an NHMRC Early Career Fellow, Chairs the Antiretroviral Guidelines Committee for the Australasian Society for HIV, Viral Hepatitis and Sexual Health Medicine (ASHM) and sits on the ASHM Board. His research interests are in clinical trials focused on HIV Cure and antiretroviral therapy. Specific interests include developing non-invasive imaging methods to locate and quantify tissue sites of HIV and clinical trials of interventions targeting the HIV reservoir including latency reversal agents and agents to increase HIV-specific immune responses.

External positions

Head Clinical Research Unit, Department of Infectious Diseases, Alfred Health

Infectious Diseases Physician, Alfred Health

Infectious Diseases Physician, Monash Health

Keywords

  • HIV
  • HIV Cure
  • Infectious Diseases
  • Antiretroviral Therapy
  • Imaging
  • Clinical Trials

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Projects 2011 2020

Research Output 2003 2019

Clinical trials of antiretroviral treatment interruption in HIV-infected individuals

Lau, J. S. Y., Smith, M. Z., Lewin, S. R. & McMahon, J. H., 1 Apr 2019, In : AIDS. 33, 5, p. 773-791 19 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Identification of 5-Substituted 2-Acylaminothiazoles That Activate Tat-Mediated Transcription in HIV-1 Latency Models

Nguyen, W., Jacobson, J., Jarman, K. E., Jousset Sabroux, H., Harty, L., McMahon, J., Lewin, S. R., Purcell, D. F. & Sleebs, B. E., 23 May 2019, In : Journal of Medicinal Chemistry. 62, 10, p. 5148-5175 28 p.

Research output: Contribution to journalArticleResearchpeer-review

Population Pharmacokinetics and Pharmacodynamics of Disulfiram on Inducing Latent HIV-1 Transcription in a Phase IIb Trial

Lee, S. A., Elliott, J. H., McMahon, J., Hartogenesis, W., Bumpus, N. N., Lifson, J. D., Gorelick, R. J., Bacchetti, P., Deeks, S. G., Lewin, S. R. & Savic, R. M., 1 Mar 2019, In : Clinical Pharmacology and Therapeutics. 105, 3, p. 692-702 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Recruiting people with HIV to an online self-management support randomised controlled trial: Barriers and facilitators

Klassen, K. M., Millard, T., Stout, J., McDonald, K., Dodson, S., Osborne, R. H., Battersby, M. W., Fairley, C. K., Kidd, M. R., McMahon, J., Baker, D. & Elliott, J. H., Jun 2019, (Accepted/In press) In : Sexual Health. 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Routine versus Targeted Viral Load Strategy among Patients Starting Antiretroviral in Hanoi, Vietnam

Pollack, T. M., Duong, H. T., Pham, T. T., Nguyen, T. D., Libman, H., Ngo, L., McMahon, J. H., Elliott, J. H., Do, C. D. & Colby, D. J., 1 Mar 2019, In : Journal of the International AIDS Society. 22, 3, 9 p., e25258.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Activities 2014 2018

  • 4 Thesis Examination

Press / Media

Trial Finds Hidden HIV

James McMahon

30/11/18

1 media contribution

Press/Media: Research

New Research Aims to Unearth Hidden HIV

James McMahon

30/11/18

1 item of media coverage

Press/Media: Article/Feature

Drug for alcoholism can unmask HIV hiding in cells

James McMahon

17/11/18

1 item of media coverage

Press/Media: Research

Anti-booze drug may flush out dormant HIV and could lead to cure

James McMahon

16/11/18

1 item of media coverage

Press/Media: Research