James McMahon

Dr

  • Department of Infectious Diseases, Alfred Hospital and Central Clinical School, Monash University. Commercial Rd, Melbourne, VIC, Australia

  • Monash Medical Centre, Clayton, Australia 246 Clayton Rd, Clayton VIC 3168

Accepting PhD Students

20062020
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Personal profile

Biography

Dr McMahon is an Infectious Diseases physician and Head of Clinical Research at the Alfred Hospital and Monash University, and an Infectious Diseases Physician at Monash Medical Centre. He is an NHMRC Early Career Fellow, Chairs the Antiretroviral Guidelines Committee for the Australasian Society for HIV, Viral Hepatitis and Sexual Health Medicine (ASHM) and sits on the ASHM Board. His research interests are in clinical trials focused on HIV Cure and antiretroviral therapy. Specific interests include developing non-invasive imaging methods to locate and quantify tissue sites of HIV and clinical trials of interventions targeting the HIV reservoir including latency reversal agents and agents to increase HIV-specific immune responses.

Education/Academic qualification

HIV Clinical Research, PhD, MONASH UNIVERSITY

Epidemiology, MPH, Tufts University

Infectious Diseases, FRACP, Royal Australasian College of Physicians

Clinical Medicine, MBBS, University of Melbourne

External positions

Head Clinical Research Unit, Department of Infectious Diseases, Alfred Health

Infectious Diseases Physician, Alfred Health

Infectious Diseases Physician, Monash Health

Research area keywords

  • HIV
  • HIV Cure
  • Infectious Diseases
  • Antiretroviral Therapy
  • Imaging
  • Clinical Trials

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Projects 2011 2020

Research Output 2006 2019

1 Citation (Scopus)

Clinical trials of antiretroviral treatment interruption in HIV-infected individuals

Lau, J. S. Y., Smith, M. Z., Lewin, S. R. & McMahon, J. H., 1 Apr 2019, In : AIDS. 33, 5, p. 773-791 19 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Community and provider Community and provider perspectives on Treatment Interruptions in the landscape of HIV cure focused studies

Lau, J. S. Y., Smith, M. Z., Allan, B., Martinez, C., Power, J., Lewin, S. R. & McMahon, J. H., 14 Oct 2019, (Accepted/In press) In : AIDS Research and Human Retroviruses. 23 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
35 Citations (Scopus)

Dolutegravir plus lamivudine versus dolutegravir plus tenofovir disoproxil fumarate and emtricitabine in antiretroviral-naive adults with HIV-1 infection (GEMINI-1 and GEMINI-2): week 48 results from two multicentre, double-blind, randomised, non-inferiority, phase 3 trials

Cahn, P., Madero, J. S., Arribas, J. R., Antinori, A., Ortiz, R., Clarke, A. E., Hung, C. C., Rockstroh, J. K., Girard, P. M., Sievers, J., Man, C., Currie, A., Underwood, M., Tenorio, A. R., Pappa, K., Wynne, B., Fettiplace, A., Gartland, M., Aboud, M., Smith, K. & 1 others, the GEMINI Study Team, 12 Jan 2019, In : The Lancet. 393, 10167, p. 143-155 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Identification of 5-Substituted 2-Acylaminothiazoles That Activate Tat-Mediated Transcription in HIV-1 Latency Models

Nguyen, W., Jacobson, J., Jarman, K. E., Jousset Sabroux, H., Harty, L., McMahon, J., Lewin, S. R., Purcell, D. F. & Sleebs, B. E., 23 May 2019, In : Journal of Medicinal Chemistry. 62, 10, p. 5148-5175 28 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Population Pharmacokinetics and Pharmacodynamics of Disulfiram on Inducing Latent HIV-1 Transcription in a Phase IIb Trial

Lee, S. A., Elliott, J. H., McMahon, J., Hartogenesis, W., Bumpus, N. N., Lifson, J. D., Gorelick, R. J., Bacchetti, P., Deeks, S. G., Lewin, S. R. & Savic, R. M., 1 Mar 2019, In : Clinical Pharmacology and Therapeutics. 105, 3, p. 692-702 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Activities 2013 2019

Clinical research Track Committee Member. 23rd International AIDS Conference (AIDS 2020)

James McMahon (Organiser)
20192020

Activity: Participating in or organising an event typesContribution to conference

AIDS Research and Therapy (Journal)

James McMahon (Editorial board member)
2019

Activity: Publication peer-review and editorial work typesEditorial responsibility

Chair - Data Safety Monitoring Committee SMILE-C Trial

James McMahon (Chair/ Co-Chair)
Feb 2019

Activity: External Academic EngagementPeer review panel or committee

Press / Media

Trial Finds Hidden HIV

James McMahon

30/11/18

1 Media contribution

Press/Media: Research

New Research Aims to Unearth Hidden HIV

James McMahon

30/11/18

1 item of Media coverage

Press/Media: Article/Feature

Drug for alcoholism can unmask HIV hiding in cells

James McMahon

17/11/18

1 item of Media coverage

Press/Media: Research

Anti-booze drug may flush out dormant HIV and could lead to cure

James McMahon

16/11/18

1 item of Media coverage

Press/Media: Research