Prof James McMahon is a dedicated clinician-scientist with a growing national and international reputation for excellence in Infectious Diseases. Prior to completing his PhD at Monash University in 2013, Prof McMahon worked as an Infectious Disease Physician at the Alfred Hospital and Monash Medical Centre. He is currently appointed as the Head of the Clinical Research Unit at the Department of Infectious Diseases (Alfred Hospital; Monash Uni).

Prof McMahon has received substantial competitive fellowship and grant funding totalling $50,590,729.50 to date, from (including but not limited to) MRFF, NHMRC, Australian Centre for HIV and Hepatitis Virology Research, NIH, Melbourne HIV Cure Consortium,  and several charitable foundations.

Prof McMahon's research interests include clinical trials focused on HIV and COVID-19. Specific interests include trials in HIV Cure developing non-invasive imaging methods to locate and quantify tissue sites of HIV and clinical trials of interventions targeting the HIV reservoir with latency reversal agents and immunotherapeutics. For COVID-19 he studies treatment and vaccnation strategies in high risk groups. He leads an adaptive randomised trial of COVID-19 vaccine booster strategies in immunocompromised hosts, detailed immune profiling of high risk groups post COVID vaccines and a large prospective biobank of biological samples with matched clinical data post infection.

Prof McMahon is the current President for the Australasian Society for HIV, Viral Hepatitis and Sexual Health Medicine (ASHM) and is the co-convener for the 2024 ASHM conference. He sits on the National Clinical Evidence Taskforce committees for COVID-19 Therapeutics and National Monkeypox Taskforce.

He has been an invited as a reviewer for the NHMRC Ideas Grant Panel, European Research Council and the MRFF Early to Mid-Career Researchers Grant Panel.

Prof McMahon holds several distinguished positions across various Journals including being on the Editorial Board for PLoS One, AIDS Research and Therapy and the Australian Prescriber

Other notable services include leading the IAS 2023 Organizing Committee and invitation to the AFAO Expert Advisory panel on strategies to end HIV in Australia by 2025.