Projects per year
Personal profile
Biography
Dr Harris is an Immunologist/Cell Biologist with an interest in autophagy, endocytosis, macrophage and dendritic cell biology, inflammation and host-pathogen interactions. He heads laboratory research for the Rheumatology Group with Professor Eric Morand and is focused on innate immune responses and inflammation in autoimmune diseases, including systemic lupus erythematosus (SLE, lupus), systemic sclerosis (SSc, scleroderma) and arthritis. He is also investigating the role of macrophage migration inhibitory factor (MIF) in inflammation and cell biology.
Dr Harris received a BSc (Hons) in Zoology from the University of Nottingham (UK) and his PhD in Immunology from the University of the West of England (UK). He has work as a postdoctoral fellow at the Institute for Animal Health (UK), Oxford University, University of New Mexico and Trinity College Dublin. He was also Programme Manager for the Immunology Research Centre (IRC) in Ireland. He moved to Australia and Monash in 2013.
He has publised >65 articles, with more than 12,500 citations in Google Scholar (>7,600 citations in Scopus).
Research interests
Dr Harris has an interest in innate immunity and the regulation of inflammation, particularly cytokine release by macrophages and dendritic cells. Recently, he has focused on the regulation of IL-1 family cytokines and macrophage migration inhibitory factor (MIF). In addition, he also works on the roles of autophagy in immune cells.
In addition, the Rheumatology Group has a strong interest in biomarker studies in diseases, including SLE, arthritis and scleroderma.
Community service
Scientists In Schools
Day of Immunology Organising committee (Melbourne) 2014
Monash teaching commitment
Department Convenor, MHTP, BMS3990 Research in Action
Education/Academic qualification
Immunology, PhD, University of the West of England
… → 2000
Zoology, BSc (Hons), The University of Nottingham (UK)
… → 1995
Keywords
- Arthritis
- Autophagy
- Dendritic Cell
- Immunity
- Inflammation
- Lupus
- Macrophage
- tuberculosis
- innate immunity
- scleroderma
- MIF
- Inflammasomes
- IL-1
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2014 2018
Interleukin-1b biology: mechanisms of regulation, activation and secretion
Vince, J., Masters, S. L. & Harris, J.
National Health & Medical Research Council (NHMRC)
1/01/16 → 31/12/18
Project: Research
New therapeutic targets in rheumatological diseases
Harris, J., Jones, S. & Morand, E. F.
The Rebecca L Cooper Medical Research Foundation
1/01/15 → 31/12/15
Project: Research
Targeting autophagy as a means of control of cytokine production in SLE
National Health & Medical Research Council (NHMRC)
1/01/14 → 31/12/16
Project: Research
Research Output 1998 2018
All-trans retinoic acid augments autophagy during intracellular bacterial infection
Coleman, M. M., Basdeo, S. A., Coleman, A. M., Ni Cheallaigh, C., Peral de Castro, C., McLaughlin, A. M., Dunne, P. J., Harris, J. & Keane, J., 1 Nov 2018, In : American Journal of Respiratory Cell and Molecular Biology. 59, 5, p. 548-556 9 p.Research output: Contribution to journal › Article › Research › peer-review
Analysis of serum interleukin (IL)-1β and IL-18 in systemic lupus erythematosus
Mende, R., Vincent, F. B., Kandane-Rathnayake, R., Koelmeyer, R., Lin, E., Chang, J., Hoi, A., Morand, E. F., Harris, J. & Lang, T., 7 Jun 2018, In : Frontiers in Immunology. 9, JUN, 10 p., 1250.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Effect of storage duration on cytokine stability in human serum and plasma
Vincent, F. B., Nim, H. T., Lee, J. P. W., Morand, E. F. & Harris, J., 1 Jan 2018, (Accepted/In press) In : Cytokine. 5 p.Research output: Contribution to journal › Article › Research › peer-review
Macrophage migration inhibitory factor is required for NLRP3 inflammasome activation
Lang, T., Lee, J. P. W., Elgass, K., Pinar, A. A., Tate, M. D., Aitken, E. H., Fan, H., Creed, S. J., Deen, N. S., Traore, D. A. K., Mueller, I., Stanisic, D., Baiwog, F. S., Skene, C., Wilce, M. C. J., Mansell, A., Morand, E. F. & Harris, J., 1 Dec 2018, In : Nature Communications. 9, 1, 15 p., 2223.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Mitophagy and the release of inflammatory cytokines
Harris, J., Deen, N., Zamani, S. & Hasnat, M. A., 1 Jul 2018, In : Mitochondrion. 41, p. 2-8 7 p.Research output: Contribution to journal › Review Article › Other › peer-review
Activities 2015 2019
Immunology and Cell Biology (Journal)
James Harris (Associate editor)2019 → 2021
Activity: Publication peer-review and editorial work types › Editorial responsibility
ComBio 2018
James Harris (Session chair)2018
Activity: Participating in or organising an event types › Contribution to conference
PeerJ (Journal)
James Harris (Associate editor)2017 → …
Activity: Publication peer-review and editorial work types › Editorial responsibility
Immunology and Cell Biology (Journal)
James Harris (Associate editor)2016 → …
Activity: Publication peer-review and editorial work types › Editorial responsibility
Arthritis Research and Therapy (Journal)
James Harris (Editorial board member)2016 → …
Activity: Publication peer-review and editorial work types › Editorial responsibility