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Personal profile

Biography

Dr Harris is an Immunologist/Cell Biologist with an interest in autophagy, endocytosis, macrophage and dendritic cell biology, inflammation and host-pathogen interactions. He heads laboratory research for the Rheumatology Group with Professor Eric Morand and is focused on innate immune responses and inflammation in autoimmune diseases, including systemic lupus erythematosus (SLE, lupus), systemic sclerosis (SSc, scleroderma) and arthritis. He is also investigating the role of macrophage migration inhibitory factor (MIF) in inflammation and cell biology.

Dr Harris received a BSc (Hons) in Zoology from the University of Nottingham (UK) and his PhD in Immunology from the University of the West of England (UK). He has work as a postdoctoral fellow at the Institute for Animal Health (UK), Oxford University, University of New Mexico and Trinity College Dublin. He was also Programme Manager for the Immunology Research Centre (IRC) in Ireland. He moved to Australia and Monash in 2013.

He has publised >65 articles, with more than 12,500 citations in Google Scholar (>7,600 citations in Scopus).

 

Research interests

Dr Harris has an interest in innate immunity and the regulation of inflammation, particularly cytokine release by macrophages and dendritic cells. Recently, he has focused on the regulation of IL-1 family cytokines and macrophage migration inhibitory factor (MIF). In addition, he also works on the roles of autophagy in immune cells.

In addition, the Rheumatology Group has a strong interest in biomarker studies in diseases, including SLE, arthritis and scleroderma.

Community service

Scientists In Schools

Day of Immunology Organising committee (Melbourne) 2014

 

Monash teaching commitment

Department Convenor, MHTP, BMS3990 Research in Action

Education/Academic qualification

Immunology, PhD, University of the West of England

… → 2000

Zoology, BSc (Hons), The University of Nottingham (UK)

… → 1995

Keywords

  • Arthritis
  • Autophagy
  • Dendritic Cell
  • Immunity
  • Inflammation
  • Lupus
  • Macrophage
  • tuberculosis
  • innate immunity
  • scleroderma
  • MIF
  • Inflammasomes
  • IL-1

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2014 2018

Research Output 1998 2018

All-trans retinoic acid augments autophagy during intracellular bacterial infection

Coleman, M. M., Basdeo, S. A., Coleman, A. M., Ni Cheallaigh, C., Peral de Castro, C., McLaughlin, A. M., Dunne, P. J., Harris, J. & Keane, J., 1 Nov 2018, In : American Journal of Respiratory Cell and Molecular Biology. 59, 5, p. 548-556 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Analysis of serum interleukin (IL)-1β and IL-18 in systemic lupus erythematosus

Mende, R., Vincent, F. B., Kandane-Rathnayake, R., Koelmeyer, R., Lin, E., Chang, J., Hoi, A., Morand, E. F., Harris, J. & Lang, T., 7 Jun 2018, In : Frontiers in Immunology. 9, JUN, 10 p., 1250.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Effect of storage duration on cytokine stability in human serum and plasma

Vincent, F. B., Nim, H. T., Lee, J. P. W., Morand, E. F. & Harris, J., 1 Jan 2018, (Accepted/In press) In : Cytokine. 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Macrophage migration inhibitory factor is required for NLRP3 inflammasome activation

Lang, T., Lee, J. P. W., Elgass, K., Pinar, A. A., Tate, M. D., Aitken, E. H., Fan, H., Creed, S. J., Deen, N. S., Traore, D. A. K., Mueller, I., Stanisic, D., Baiwog, F. S., Skene, C., Wilce, M. C. J., Mansell, A., Morand, E. F. & Harris, J., 1 Dec 2018, In : Nature Communications. 9, 1, 15 p., 2223.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Mitophagy and the release of inflammatory cytokines

Harris, J., Deen, N., Zamani, S. & Hasnat, M. A., 1 Jul 2018, In : Mitochondrion. 41, p. 2-8 7 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

Activities 2015 2019

  • 7 Editorial responsibility
  • 1 Contribution to conference

Immunology and Cell Biology (Journal)

James Harris (Associate editor)
20192021

Activity: Publication peer-review and editorial work typesEditorial responsibility

ComBio 2018

James Harris (Session chair)
2018

Activity: Participating in or organising an event typesContribution to conference

PeerJ (Journal)

James Harris (Associate editor)
2017 → …

Activity: Publication peer-review and editorial work typesEditorial responsibility

Immunology and Cell Biology (Journal)

James Harris (Associate editor)
2016 → …

Activity: Publication peer-review and editorial work typesEditorial responsibility

Arthritis Research and Therapy (Journal)

James Harris (Editorial board member)
2016 → …

Activity: Publication peer-review and editorial work typesEditorial responsibility