1998 …2105
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Personal profile

Biography

I am an Immunologist/Cell Biologist with an interest in autophagy, endocytosis, macrophage and dendritic cell biology, inflammation and host-pathogen interactions. I have previously worked on innate immunity to tuberculosis. I currently work on innate immune responses and inflammation in autoimmune diseases, including systemic lupus erythematosus (SLE, lupus) and arthritis. I am also investigating the role of macrophage migration inhibitory factor (MIF) in inflammation.

My specific interests are the role of autophagy in the regulation of cytokine secretion and inflammation, as well as its role in the response to pathogens, including Mycobacterium tuberculosis, the bacterium that causes tuberculosis in humans. I am also currently investigating the mechanisms through with macrophage migration inhibitory factor (MIF) influences inflammation, particularly in autoimmune diseases.

Our research aims are to better understand the mechanisms that control inflammation in autoimmune diseases such as SLE, arthritis and psoriasis. By gaining a clearer understanding of the molecular pathways that control inflammation, we can develop more targeted therapeutic approaches to the treatment of inflammatory disease.

 

Related Links:

Research interests

Autophagy and Inflammation

Cell Biology

Innate Immunity

Autoimmunity - lupus, arthritis, psoriasis

Tuberculosis

Community service

Scientists In Schools (Victoria)

Keywords

  • Arthritis
  • Autophagy
  • Dendritic Cell
  • Immunity
  • Inflammation
  • Lupus
  • Macrophage
  • tuberculosis

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2014 2105

Research Output 1998 2018

All-trans Retinoic Acid Augments Autophagy during Intracellular Bacterial Infection

Coleman, M. M., Basdeo, S. A., Coleman, A. M., Ni Cheallaigh, C., Peral de Castro, C., McLaughlin, A. M., Dunne, P. J., Harris, J. & Keane, J. 31 May 2018 (Accepted/In press) In : American Journal of Respiratory Cell and Molecular Biology. 30 p.

Research output: Contribution to journalArticle

Open Access
File

Effect of storage duration on cytokine stability in human serum and plasma

Vincent, F. B., Nim, H. T., Lee, J. P. W., Morand, E. F. & Harris, J. 2018 (Accepted/In press) In : Cytokine. p. 1-5 5 p.

Research output: Contribution to journalArticle

Macrophage migration inhibitory factor is required for NLRP3 inflammasome activation

Lang, T., Lee, J. P. W., Elgass, K., Pinar, A. A., Tate, M. D., Aitken, E. H., Fan, H., Creed, S. J., Deen, N. S., Traore, D. A. K., Mueller, I., Stanisic, D., Baiwog, F. S., Skene, C., Wilce, M. C. J., Mansell, A., Morand, E. F. & Harris, J. 1 Dec 2018 In : Nature Communications. 9, 1, 15 p., 2223

Research output: Contribution to journalArticle

Open Access
File

Mitophagy and the release of inflammatory cytokines

Harris, J., Deen, N., Zamani, S. & Hasnat, M. A. 1 Jul 2018 In : Mitochondrion. 41, p. 2-8 7 p.

Research output: Contribution to journalReview Article

Activities 2015 2017

  • 6 Editorial responsibility

PeerJ (Journal)

Harris, J. (Associate editor)
2017 → …

Activity: Editorial responsibility

Immunology and Cell Biology (Journal)

Harris, J. (Associate editor)
2016 → …

Activity: Editorial responsibility

Arthritis Research and Therapy (Journal)

Harris, J. (Editorial board member)
2016 → …

Activity: Editorial responsibility

Frontiers in Immunology (Journal)

Harris, J. (Associate editor)
2016 → …

Activity: Editorial responsibility

Frontiers in Immunology (Journal)

Harris, J. (Guest editor)
2015

Activity: Editorial responsibility