Projects per year
Personal profile
Biography
Dr Deane studies the biology of epithelial cells in the uterus and the kidney. Epithelial cells form a layer lining glandular and tubular strucutres in these organs and are involved in regenerative processes after injury and during the normal female reproductive cycle. Understanding the regenerative capacity of epithelial cells in the uterus will aid the treatment of infertility and conditions such as endometriosis. Characterising epithelial regeneration mechanisms in the kidney may identify methods of hastening recovery from acute renal injury and provide insight into the epithelial defects causing polycystic kidney disease.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Projects
- 6 Finished
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Cells and nanobiomaterials to treat and prevent Pelvic Organ Prolapse
Gargett, C., Mukherjee, S., Brosens, J. J., Werkmeister, J. A., Rosamilia, A., Deane, J., Ott, S., Arkwright, J. W. & Weiss, A. S.
1/01/19 → 31/12/22
Project: Research
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Progenitor origin and regulation in endometrial regeneration
National Health and Medical Research Council (NHMRC) (Australia)
1/01/15 → 31/12/18
Project: Research
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Sonic Hedgehog as a Regulator of Endometrial Mesenchymal Stem/Stromal Cell Activity
Deane, J. A., 5 Feb 2020, In: Molecular Therapy. 28, 2, p. 350-351 2 p.Research output: Contribution to journal › Comment / Debate › Other › peer-review
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The effects of hedgehog ligand neutralising antibody 5E1 in a mouse model of endometriosis
Cousins, F. L., Farley, J. K., Kerrigan, R., Mukherjee, S., Darzi, S., Gargett, C. E. & Deane, J. A., 25 Sep 2020, In: BMC Research Notes. 13, 1, 6 p., 454.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
Bone marrow-derived endometrial cells Transdifferentiation or misidentification?
Deane, J. A., Ong, Y., Cousins, F. L. & Gargett, C. E., 1 Mar 2019, In: Human Reproduction Update. 25, 2, p. 272-273 2 p.Research output: Contribution to journal › Letter › Other › peer-review
6 Citations (Scopus) -
Endometrial mesenchymal stem/stromal cell modulation of T cell proliferation
Yang, X., Devianti, M., Yang, Y. H., Ong, Y. R., Tan, K. S., Gurung, S., Tan, J. L., Zhu, D., Lim, R., Gargett, C. E. & Deane, J. A., 1 Jan 2019, In: Reproduction. 157, 1, p. 43-52 10 p.Research output: Contribution to journal › Article › Research › peer-review
10 Citations (Scopus) -
Regulatory T Cell Transmigration and Intravascular Migration Undergo Mechanistically Distinct Regulation at Different Phases of the Inflammatory Response
Snelgrove, S. L., Abeynaike, L. D., Thevalingam, S., Deane, J. A. & Hickey, M. J., 1 Dec 2019, In: Journal of Immunology. 203, 11, p. 2850-2861 12 p.Research output: Contribution to journal › Article › Research › peer-review
9 Citations (Scopus)