Projects per year
Personal profile
Biography
Associate Professor Jake Shortt is the Head of Haematology Research at the School of Clinical Sciences and clinical lead at Monash Haematology for leukaemia and myelodysplasia. He is Principal Investigator on a range of clinical trials for myeloid malignancies, conducted through the Monash Haematology clinical trials unit. He is also a Principal Investigator on academically-funded and investigator-initiated trials in multiple myeloma and lymphoma.
Associate Professor Shortt is the recipient of a Medical Research Future Fund Career Development Fellowship as part of the Next Generation Clinical Researchers Program. His strong translational work in the School of Clinical Sciences is focused on strategies incorporating epigenetic drugs with immunotherapy in haematological cancers, particularly lymphoma and multiple myeloma. He heads the Blood Cancer Therapeutics laboratory within the Monash Health Translation Precinct, facilitating bench-to-bedside research in order to progress these new treatments into the haematology clinic.
In addition to his clinical and research roles, Associate Professor Shortt is the Chair of the Laboratory Sciences Committee of the Australasian Leukaemia and Lymphoma Group and sits on the steering committees of the Australian TTP registry, the Australian Lymphoma and Related Diseases Registry and the Victorian Epigenetics Group.
Clinical activities
Associate Professor Shortt is clinical lead at Monash Health for leukaemia and myelodysplasia. He is also the Deputy Unit Head of Laboratory Haematology. He attends the Monash Haematology myeloid disorders clinic and runs a sub-specialty service for patients with chronic myeloid leukaemia. In addition to outpatient clinics, Associate Professor Shortt undertakes inpatient ward service at Monash Health, and is Principal Investigator at Monash Health for a range of clinical trials in leukaemia and myelodysplasia.
External positions
Honorary Principal Fellow, University of Melbourne
31 Jan 2019 → …Honorary Senior Research Scientist, Peter MacCallum Cancer Centre
1 Oct 2015 → …Consultant Haematologist, Monash Health
1 Feb 2008 → …Research area keywords
- Cancer Immunology
- Epigenetics
- Leukemia
- Lymphoma
- Molecular Oncology
- Myelodysplasia
- Myeloma
- Thrombotic thrombocytopenic purpura
- cMYC
Network
Recent external collaboration on country level. Dive into details by clicking on the dots or
Projects
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A Phase 3, Double-blind, Randomized Study to Compare the Efficacy and Safety of Luspatercept (ACE-536) Versus Placebo in Subjects with Myeloproliferative Neoplasm-Associated Myelofibrosis on Concomitant JAK2 Inhibitor Therapy and Who Require Red Blood Cell Transfusions
4/03/21 → 3/03/26
Project: Research
Research output
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Cardiovascular Safety of Nilotinib in Alzheimer Disease
Tan, S., Baggio, D., Shortt, J. & Ko, B., Jan 2021, In : Annals of Neurology. 89, 1, p. 196 1 p.Research output: Contribution to journal › Letter › Other › peer-review
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Excellent outcomes in older patients with primary CNS lymphoma treated with R-MPV/cytarabine without whole brain radiotherapy or autologous stem cell transplantation therapy
Tatarczuch, M., Paul, E., Gilberston, M., Gregory, G. P., Tam, C., Quach, H., Bazargan, A., Filshie, R., Ku, M., Tey, A., Shortt, J. & Opat, S., 2 Jan 2021, In : Leukemia and Lymphoma. 62, 1, p. 112-117 6 p.Research output: Contribution to journal › Article › Research › peer-review
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Impact of COVID-19 Pandemic Isolation Measures on the Rate of Non-COVID Infections in Hematology Patients
Miller, J., Opat, S., Shortt, J., Kotsanas, D., Dendle, C. & Graham, M., Feb 2021, In : Infection Control and Hospital Epidemiology. 42, 2, p. 233-235 3 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Mycosis fungoides and Sézary syndrome: Australian clinical practice statement
Bhabha, F. K., McCormack, C., Wells, J., Campbell, Newland, K., Lade, S., Buelens, O., Joske, D., Shortt, J., Mapp, S., Radeski, D., Hertzberg, M., Khot, A., Van Der Weyden, C., Khoo, C., Hawkes, E. & Prince, H. M., Feb 2021, In : Australasian Journal of Dermatology. 62, 1, p. e8-e18 11 p.Research output: Contribution to journal › Review Article › Research › peer-review
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A novel CDK9 inhibitor increases the efficacy of venetoclax (ABT-199) in multiple models of hematologic malignancies
Phillips, D. C., Jin, S., Gregory, G. P., Zhang, Q., Xue, J., Zhao, X., Chen, J., Tong, Y., Zhang, H., Smith, M., Tahir, S. K., Clark, R. F., Penning, T. D., Devlin, J. R., Shortt, J., Hsi, E. D., Albert, D. H., Konopleva, M., Johnstone, R. W., Leverson, J. D. & 1 others, , 1 Jun 2020, In : Leukemia. 34, 6, p. 1646-1657 12 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access9 Citations (Scopus)
Prizes
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Albert Baikie Memorial Medal (2011)
Shortt, Jake (Recipient), 2011
Prize: Prize (including medals and awards)
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Joseph F Sambrook Prize for Research Excellence (2015)
Shortt, Jake (Recipient), 2015
Prize: Prize (including medals and awards)
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Prize for Preclinical Myeloma Research (2015)
Shortt, Jake (Recipient), 2015
Prize: Prize (including medals and awards)
Activities
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European Hematology Association (External organisation)
Jake Shortt (Member)
2018Activity: Industry, Government and Philanthropy Engagement and Partnerships › Membership of networks of excellence
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Standing Research Sub-Committee - Cancer Council Victoria
Jake Shortt (Member)
2017Activity: External Academic Engagement › Committees and working groups
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Steering Committee - A trial of tranexamic acid for low platelet counts (TREATT)
Jake Shortt (Advisor)
2017 → …Activity: External Academic Engagement › Committees and working groups
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Chemical Probes Portal (External organisation)
Jake Shortt (Member)
2017Activity: Industry, Government and Philanthropy Engagement and Partnerships › Membership of an advisory panel/policy group/ board
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eviQ Haematology Reference Committee
Jake Shortt (Member)
2016 → 2019Activity: External Academic Engagement › Committees and working groups