20132020

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2020

Correction: NK cell-derived GM-CSF potentiates inflammatory arthritis and is negatively regulated by CIS

Louis, C., Souza-Fonseca-Guimaraes, F., Yang, Y., D'Silva, D., Kratina, T., Dagley, L., Hediyeh-Zadeh, S., Rautela, J., Masters, S. L., Davis, M. J., Babon, J. J., Ciric, B., Vivier, E., Alexander, W. S., Huntington, N. D. & Wicks, I. P., 4 May 2020, In : Journal of Experimental Medicine. 217, 5, 1 p.

Research output: Contribution to journalArticleOtherpeer-review

Open Access
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Harnessing Natural Killer Immunity in Metastatic SCLC

Best, S. A., Hess, J. B., Souza-Fonseca-Guimaraes, F., Cursons, J., Kersbergen, A., Dong, X., Rautela, J., Hyslop, S. R., Ritchie, M. E., Davis, M. J., Leong, T. L., Irving, L., Steinfort, D., Huntington, N. D. & Sutherland, K. D., 2020, (Accepted/In press) In : Journal of Thoracic Oncology. 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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miR17~92 restrains pro-apoptotic BIM to ensure survival of haematopoietic stem and progenitor cells

Brinkmann, K., Ng, A. P., de Graaf, C. A., Di Rago, L., Hyland, C. D., Morelli, E., Rautela, J., Huntington, N. D., Strasser, A., Alexander, W. S. & Herold, M. J., May 2020, In : Cell Death and Differentiation. 27, 5, p. 1475-1488 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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NK cell–derived GM-CSF potentiates inflammatory arthritis and is negatively regulated by CIS

Louis, C., Souza-Fonseca-Guimaraes, F., Yang, Y., D'Silva, D., Kratina, T., Dagley, L., Hediyeh-Zadeh, S., Rautela, J., Masters, S. L., Davis, M. J., Babon, J. J., Ciric, B., Vivier, E., Alexander, W. S., Huntington, N. D. & Wicks, I. P., 4 May 2020, In : Journal of Experimental Medicine. 217, 5, 19 p., e20191421.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
1 Citation (Scopus)

NK Cell Priming From Endogenous Homeostatic Signals Is Modulated by CIS

Delconte, R. B., Guittard, G., Goh, W., Hediyeh-Zadeh, S., Hennessy, R. J., Rautela, J., Davis, M. J., Souza-Fonseca-Guimaraes, F., Nunès, J. A. & Huntington, N. D., 31 Jan 2020, In : Frontiers in Immunology. 11, 16 p., 75.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
3 Citations (Scopus)
2019

Generation of novel Id2 and E2-2, E2A and HEB antibodies reveals novel Id2 binding partners and species-specific expression of E-proteins in NK cells

Rautela, J., Dagley, L. F., Kratina, T., Anthony, A., Goh, W., Surgenor, E., Delconte, R. B., Webb, A. I., Elwood, N., Groom, J. R., Souza-Fonseca-Guimaraes, F., Corcoran, L. & Huntington, N. D., Nov 2019, In : Molecular Immunology. 115, p. 56-63 8 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Loss-of-Function in SMAD4 Might Not Be Critical for Human Natural Killer Cell Responsiveness to TGF-β

Healy, L. P., Rossi, G. R., Rautela, J., Slade, C. A., Huntington, N. D., Winship, I. M. & Souza-Fonseca-Guimaraes, F., 1 May 2019, In : Frontiers in Immunology. 10, 8 p., 904.

Research output: Contribution to journalArticleOtherpeer-review

Open Access
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Quantifying NK cell growth and survival changes in response to cytokines and regulatory checkpoint blockade helps identify optimal culture and expansion conditions

Hennessy, R. J., Pham, K., Delconte, R., Rautela, J., Hodgkin, P. D. & Huntington, N. D., 1 Jun 2019, In : Journal of leukocyte biology. 105, 6, p. 1341-1354 14 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Therapeutic blockade of activin-A improves NK cell function and antitumor immunity

Rautela, J., Dagley, L. F., De Oliveira, C. C., Schuster, I. S., Hediyeh-Zadeh, S., Delconte, R. B., Cursons, J., Hennessy, R., Hutchinson, D. S., Harrison, C., Kita, B., Vivier, E., Webb, A. I., Degli-Esposti, M. A., Davis, M. J., Huntington, N. D. & Souza-Fonseca-Guimaraes, F., 27 Aug 2019, In : Science Signaling. 12, 596, 13 p., aat7527.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Tumor inherent interferon regulators as biomarkers of long-term chemotherapeutic response in TNBC

Brockwell, N. K., Rautela, J., Owen, K. L., Gearing, L. J., Deb, S., Harvey, K., Spurling, A., Zanker, D., Chan, C. L., Cumming, H. E., Deng, N., Zakhour, J. M., Duivenvoorden, H. M., Robinson, T., Harris, M., White, M., Fox, J., Ooi, C., Kumar, B., Thomson, J. & 7 others, Potasz, N., Swarbrick, A., Hertzog, P., Molloy, T. J., O’Toole, S., Ganju, V. & Parker, B. S., 29 Aug 2019, In : npj Precision Oncology. 3, 13 p., 21.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2018

GM-CSF quantity has a selective effect on granulocytic vs. monocytic myeloid development and function

Sun, L., Rautela, J., Delconte, R. B., Souza-Fonseca-Guimaraes, F., Carrington, E. M., Schenk, R. L., Herold, M. J., Huntington, N. D., Lew, A. M., Xu, Y. & Zhan, Y., 28 Aug 2018, In : Frontiers in Immunology. 9, 13 p., 1922.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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IMiDs prime myeloma cells for daratumumab-mediated cytotoxicity through loss of Ikaros and Aiolos

Fedele, P. L., Willis, S. N., Liao, Y., Low, M. S., Rautela, J., Segal, D. H., Gong, J. N., Huntington, N. D., Shi, W., Huang, D. C. S., Grigoriadis, G., Tellier, J. & Nutt, S. L., 15 Nov 2018, In : Blood. 132, 20, p. 2166-2178 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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11 Citations (Scopus)

Recipient BCL2 inhibition and NK cell ablation form part of a reduced intensity conditioning regime that improves allo-bone marrow transplantation outcomes

Jiao, Y., Davis, J. E., Rautela, J., Carrington, E. M., Ludford-Menting, M. J., Goh, W., Delconte, R. B., Souza-Fonseca-Guimaraes, F., Koldej, R., Gray, D., Huang, D., Kile, B. T., Lew, A. M., Ritchie, D. S. & Huntington, N. D., 12 Nov 2018, In : Cell Death and Differentiation. 26, p. 1516-1530 15 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)
2017

Cell cycle progression dictates the requirement for BCL2 in natural killer cell survival

Viant, C., Guia, S., Hennessy, R. J., Rautela, J., Pham, K., Bernat, C., Goh, W., Jiao, Y., Delconte, R., Roger, M., Simon, V., Souza-Fonseca-Guimaraes, F., Grabow, S., Belz, G. T., Kile, B. T., Strasser, A., Gray, D., Hodgkin, P. D., Beutler, B., Vivier, E. & 2 others, Ugolini, S. & Huntington, N. D., 5 Jan 2017, In : Journal of Experimental Medicine. 214, 2, p. 491-510 20 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
25 Citations (Scopus)

Myoepithelial cell-specific expression of stefin A as a suppressor of early breast cancer invasion

Duivenvoorden, H. M., Rautela, J., Edgington-Mitchell, L. E., Spurling, A., Greening, D. W., Nowell, C. J., Molloy, T. J., Robbins, E., Brockwell, N. K., Lee, C. S., Chen, M., Holliday, A., Selinger, C. I., Hu, M., Britt, K. L., Stroud, D. A., Bogyo, M., Möller, A., Polyak, K., Sloane, B. F. & 2 others, O'Toole, S. A. & Parker, B. S., 1 Dec 2017, In : Journal of Pathology. 243, 4, p. 496-509 14 p.

Research output: Contribution to journalArticleResearchpeer-review

21 Citations (Scopus)

Neoadjuvant interferons: Critical for effective PD-1–based immunotherapy in TNBC

Brockwell, N. K., Owen, K. L., Zanker, D., Spurling, A., Rautela, J., Duivenvoorden, H. M., Baschuk, N., Caramia, F., Loi, S., Darcy, P. K., Lim, E. & Parker, B. S., 1 Oct 2017, In : Cancer Immunology Research. 5, 10, p. 871-884 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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13 Citations (Scopus)

Targeting adenosine in BRAF-mutant melanoma reduces tumor growth and metastasis

Young, A., Ngiow, S. F., Madore, J., Reinhardt, J., Landsberg, J., Chitsazan, A., Rautela, J., Bald, T., Barkauskas, D. S., Ahern, E., Huntington, N. D., Schadendorf, D., Long, G. V., Boyle, G. M., Hölzel, M., Scolyer, R. A. & Smyth, M. J., 1 Sep 2017, In : Cancer Research. 77, 17, p. 4684-4696 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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33 Citations (Scopus)

Tumor immunoevasion by the conversion of effector NK cells into type 1 innate lymphoid cells

Gao, Y., Souza-Fonseca-Guimaraes, F., Bald, T., Ng, S. S., Young, A., Ngiow, S. F., Rautela, J., Straube, J., Waddell, N., Blake, S. J., Yan, J., Bartholin, L., Lee, J. S., Vivier, E., Takeda, K., Messaoudene, M., Zitvogel, L., Teng, M. W. L., Belz, G. T., Engwerda, C. R. & 4 others, Huntington, N. D., Nakamura, K., Hölzel, M. & Smyth, M. J., Sep 2017, In : Nature Immunology. 18, 9, p. 1004-1015 12 p.

Research output: Contribution to journalArticleResearchpeer-review

165 Citations (Scopus)
2016

CIS is a potent checkpoint in NK cell-mediated tumor immunity

Delconte, R. B., Kolesnik, T. B., Dagley, L. F., Rautela, J., Shi, W., Putz, E. M., Stannard, K., Zhang, J. G., Teh, C. E-Y., Firth, M., Ushiki, T., Andoniou, C. E., Degli-Esposti, M. A., Sharp, P. P., Sanvitale, C. E., Infusini, G., Liau, N. P. D., Linossi, E. M., Burns, C. J., Carotta, S. & 12 others, Gray, D. H. D., Seillet, C., Hutchinson, D. S., Belz, G. T., Webb, A. I., Alexander, W. S., Li, S. S., Bullock, A. N., Babon, J. J., Smyth, M. J., Nicholson, S. E. & Huntington, N. D., 21 Jun 2016, In : Nature Immunology. 17, 7, p. 816-824 9 p.

Research output: Contribution to journalArticleResearchpeer-review

93 Citations (Scopus)
2015

Cysteine cathepsin activity suppresses osteoclastogenesis of myeloid-derived suppressor cells in breast cancer

Edgington-Mitchell, L. E., Rautela, J., Duivenvoorden, H. M., Jayatilleke, K. M., van der Linden, W. A., Verdoes, M., Bogyo, M. & Parker, B. S., 2015, In : Oncotarget. 6, 29, p. 27008-27022 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
19 Citations (Scopus)

Loss of host type-I IFN signaling accelerates metastasis and impairs NK-cell antitumor function in multiple models of breast cancer

Rautela, J., Baschuk, N., Slaney, C. Y., Jayatilleke, K. M., Xiao, K., Bidwell, B. N., Lucas, E. C., Hawkins, E., Lock, P., Wong, C. S. F., Chen, W., Anderson, R. L., Hertzog, P. J., Andrews, D. M., Moller, A. & Parker, B. S., 2015, In : Cancer Immunology Research. 3, 11, p. 1207 - 1217 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
27 Citations (Scopus)
2014

BMP4 inhibits breast cancer metastasis by blocking myeloid-derived suppressor cell activity

Cao, Y., Slaney, C. Y., Bidwell, B. N., Parker, B. S., Johnstone, C. N., Rautela, J., Eckhardt, B. L. & Anderson, R. L., Sep 2014, In : Cancer Research. 74, 18, p. 5091-5102 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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54 Citations (Scopus)