Projects per year
Personal profile
Biography
Our laboratory investigates the role of dendritic cells in immunity with the intent of applying this knowledge to the design of immunotherapies.
I have received my PhD from The University of Western Australia, investigating the role of IL-12 in evoking anti-tumour immunity. My interest in harnessing the immune system to combat disease has led to my post-doctoral studies on dendritic cells in the laboratory of Prof Shortman at The Walter and Eliza Hall Institute. I investigated the heterogeneous nature of dendritic cells and their role in orchestrating the adaptive immune response. My analysis of dendritic cell subsets by screening for differentially expressed genes has led to the discovery of many novel genes. These molecules have allowed the dissection of the unique immune functions of dendritic cell subpopulations and provided targets for immunotherapy. In 2012, I established my own laboratory, where I continued my research on dendritic cell biology with a view that understanding the molecules that govern the specialised functions of dendritic cells will open the way to novel immunotherapies.
Research area keywords
- adjuvants
- dendritic cells
- humoral immunity
- non-human primates
- vaccines
- antigen presentation/processing
- antigen-presenting cells
- vaccination
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects
New strategies to improve personalized immunotherapy of breast cancer
Dolcetti, R., Caminschi, I., Mazzieri, R., Brown, M. A., Woodward, N. & Bennett, I.
National Breast Cancer Foundation
31/03/18 → 31/03/21
Project: Other
Protecting against malaria through liver-resident memory T cells
Fernandez-Ruiz, D., Mackay, L. K., Mueller, S. N., Caminschi, I., Bertolino, P. & Bowen, D. G.
1/01/18 → 31/12/21
Project: Research
The regulatory role of Clec12A in antigen presentation and inflammatory disease
Lahoud, M., Begun, J., Caminschi, I. & Shortman, K. D.
1/01/18 → 31/12/22
Project: Research
Targeting antigen to Clec9A on dendritic cell for humoral immunity
Heath, W. R., Caminschi, I. & Mueller, S. N.
National Health & Medical Research Council (NHMRC)
1/01/17 → 31/12/19
Project: Research
Research Output
A Natural Peptide Antigen within the Plasmodium Ribosomal Protein RPL6 Confers Liver TRM Cell-Mediated Immunity against Malaria in Mice
Valencia-Hernandez, A. M., Ng, W. Y., Ghazanfari, N., Ghilas, S., de Menezes, M. N., Holz, L. E., Huang, C., English, K., Naung, M., Tan, P. S., Tullett, K. M., Steiner, T. M., Enders, M. H., Beattie, L., Chua, Y. C., Jones, C. M., Cozijnsen, A., Mollard, V., Cai, Y., Bowen, D. G. & 15 others, , 10 Jun 2020, In : Cell Host and Microbe. 27, 6, p. 950-962 13 p.Research output: Contribution to journal › Article › Research › peer-review
2
Citations
(Scopus)
Antigen presentation by dendritic cells for B cell activation
Heath, W. R., Kato, Y., Steiner, T. M. & Caminschi, I., Jun 2019, In : Current Opinion in Immunology. 58, p. 44-52 9 p.Research output: Contribution to journal › Review Article › Research › peer-review
2
Citations
(Scopus)
Classical Type 1 Dendritic Cells Dominate Priming of Th1 Responses to Herpes Simplex Virus Type 1 Skin Infection
Harpur, C. M., Kato, Y., Dewi, S. T., Stankovic, S., Johnson, D. N., Bedoui, S., Whitney, P. G., Lahoud, M. H., Caminschi, I., Heath, W. R., Brooks, A. G. & Gebhardt, T., 1 Feb 2019, In : Journal of Immunology. 202, 3, p. 653-663 11 p.Research output: Contribution to journal › Article › Research › peer-review
Zymosan by-passes the requirement for pulmonary antigen encounter in lung tissue-resident memory CD8+ T cell development
Caminschi, I., Lahoud, M. H., Pizzolla, A. & Wakim, L. M., 21 Jan 2019, In : Mucosal Immunology. 12, p. 403-412 10 p.Research output: Contribution to journal › Article › Research › peer-review
5
Citations
(Scopus)
CD8+ T Cell Activation Leads to Constitutive Formation of Liver Tissue-Resident Memory T Cells that Seed a Large and Flexible Niche in the Liver
Holz, L. E., Prier, J. E., Freestone, D., Steiner, T. M., English, K., Johnson, D. N., Mollard, V., Cozijnsen, A., Davey, G. M., Godfrey, D. I., Yui, K., Mackay, L. K., Lahoud, M. H., Caminschi, I., McFadden, G. I., Bertolino, P., Fernandez-Ruiz, D. & Heath, W. R., 2 Oct 2018, In : Cell Reports. 25, 1, p. 68-79 13 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
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15
Citations
(Scopus)