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Personal profile

Biography

Postdoctoral Fellow, Interventional Immunology in Neonatal Diseases

Ritchie Centre

Hudson Institute of Medical Research

 

I trained for 3 years as a Medical-Technical Assistant at the School for Health and Social Affairs in Meiningen, Germany before studying biochemistry/molecular biology at the Friedrich-Schiller-University, Jena, Germany. After graduating in 2008, I applied for a PhD Fellowship at the Pharmazentrum Frankfurt (Centre for Pharmacology and Toxicology, head of department Prof. J. Pfeilschifter) at the Goethe University in Frankfurt am Main, Germany. In July 2008, I was awarded a competitive three year PhD Fellowship by the Deutsche Forschungsgemeinschaft (the German equivalent of the NHMRC). Under supervision of Prof. Heiko Mühl, I studied the expression regulation and function of interleukin-22 and completed my PhD in Theoretical Medicine in February 2012. Following my interests in cytokine biology and in the role of cytokines in inflammatory diseases especially of neonates, I joined the group of Dr. Marcel Nold and Dr. Claudia Nold at the Ritchie Centre in April 2012. Since then, I work on IL-37 and IL-38 and their potential in becoming new therapeutics for inflammatory diseases.

Keywords

  • Cytokines
  • Immune System Disorders
  • Immune system
  • Immunology
  • Inflammation
  • Inflammatory diseases
  • Premature babies
  • autoimmune diseases/drug therapy/genetics/immunology
  • calcimycin/pharmacology
  • calcium ionophores/ph

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Research Output 2010 2017

Homodimerization attenuates the anti-inflammatory activity of interleukin-37

Ellisdon, A. M., Nold-Petry, C. A., D'Andrea, L., Cho, S. X., Lao, J. C., Rudloff, I., Ngo, D., Lo, C. Y., Soares da Costa, T. P., Perugini, M. A., Conroy, P. J., Whisstock, J. C. & Nold, M. F., 10 Feb 2017, In : Science Immunology. 2, 8, 12 p., eaaj1548.

Research output: Contribution to journalArticleResearchpeer-review

Monocytes and dendritic cells are the primary sources of interleukin 37 in human immune cells

Rudloff, I., Cho, S. X., Lao, J. C., Ngo, D., McKenzie, M., Nold-Petry, C. A. & Nold, M. F., 1 Apr 2017, In : Journal of leukocyte biology. 101, 4, p. 901-911 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Refining anti-inflammatory therapy strategies for bronchopulmonary dysplasia

Rudloff, I., Cho, S. X., Bui, C. B., Mclean, C., Veldman, A., Berger, P. J., Nold, M. F. & Nold-Petry, C. A., Jun 2017, In : Journal of Cellular and Molecular Medicine. 21, 6, p. 1128-1138 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Airway remodeling and hyperreactivity in a model of bronchopulmonary dysplasia and their modulation by IL-1Ra

Royce, S. G., Nold, M. F., Bui, C. B-Q., Donovan, C., Lam, M., Lamanna, E., Rudloff, I., Bourke, J. E. & Nold-Petry, C. A., 1 Dec 2016, In : American Journal of Respiratory Cell and Molecular Biology. 55, 6, p. 858-868 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Clinical associations of IL-10 and IL-37 in systemic lupus erythematosus

Godsell, J., Rudloff, I., Kandane-Rathnayake, R., Hoi, A., Nold, M. F., Morand, E. F. & Harris, J., 6 Oct 2016, In : Scientific Reports. 6, 34604.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File