Projects per year
Personal profile
Biography
Professor Iekhsan Othman holds the position of Professor of Biochemistry and Deputy Head of School (Graduate Research) in the Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia since 2006. He was the Campus Graduate Committee Chairman who oversees all postgraduate activities in the campus (2016-2018). Previously he was Professor in the Department of Molecular Medicine, Faculty of Medicine, University of Malaya. He holds a bachelor degree from Bristol University (Biochemistry) with honours, and a doctorate in Molecular Neurobiology from Imperial College of Science, Technology and Medicine, London University. He joined the University of Malaya as a lecturer in 1983 and during his career as a faculty member of the Faculty of Medicine, he was the Head of Department of Biochemistry (now Department of Molecular Medicine, 1996-2000) and Deputy Dean (Development and Infrastructure, 2000-2003) of the Faculty.
As an educator and teacher, he has also been involved in teaching of biochemistry, neurochemistry, and toxicology to medical, dental, nursing, pharmacy, science and medical technologists students in the designated Medical, Dental and Science Faculties. Currently, he is involved in teaching of the medical and pharmacy students in Monash University Malaysia. He is research-active in the fields of neurotoxicology, natural products chemistry, cancer and proteomics. He has published more than 170 publications in various international, national and specialized journals in his field of research, with more than 150 publications in ISI/Scopus journals. He was a recipient of the prestigious Fulbright Scholar programme (1988/89), the Chevening Malaysian Royal Society from the British Council (1994/95) during his sabbaticals in the United States and United Kingdom, respectively. He has also received the Japanese Society for the Promotion of Science (JSPS) award twice in the year 1995 and 2000 for advanced research on marine toxins and neurophysiology in Japan. He is the recipient of the University of Malaya’s Excellence Service Award from 1999 until 2002 and Monash University Pro-Vice Chancellor Excellence Awards for administration and research for 5 years from 2009 until 2013. He has been instrumental in setting up the animal and marine toxinology section of ‘Venom and Toxin’ research group at the University of Malaya, and currently, continuing his investigation on Malaysian snake venoms and their neurotoxins, and other biologically active molecules in Monash University Malaysia.
With the advancement of proteomics technology, Professor Iekhsan was a pioneer in setting up the Malaysian Proteomic Analysis Facilities (MAPAF), a research facility, fully sponsored by the National Biotechnology Directorate, Ministry of Science, Technology, and Environment (MOSTE) in 2002. Currently, he is the director of the Proteomics and Metabolomics platform, which also includes the newly established Agilent Integarted Biology Facility@Monash Malaysia which is a joint collaboration laboratory, in Monash University Malaysia with two QToFs, two triple quadrupole, GC-MS, Atomic absorption, supercritical LC and the new Bio-LC, capabilities. In June 2003 until March 2004, he was appointed Principal Investigator and Chief Executive Officer at Cancer Research Initiative Foundation (CARIF), looking into the genomics and proteomics research of Malaysian cancer especially on oral cancer, breast cancer and nasopharyngeal carcinoma. At the same time, he has been involved with the setting up of the Quality Management System (QMS), leading to the successful certification of the Faculty of Medicine and University of Malaya Medical Centre with MS-ISO 9001:2000 by SIRIM Sdn Bhd, in 2002. He was the Management Representative for the Faculty of Medicine, throughout the preparatory process for the certification for the Faculty of Medicine (1997-2003). At the national level, he has been on the board of interview for the Rhodes Scholar program for the British Council, a consultant and examiner for the Malaysian Examination Board, Malaysian Venture Capitals Sdn. Bhd and Cancer Research Initiative Foundation. He sits in the various grant panels for the Ministry of Science, technology and Innovation for the various funding schemes awarded by the Ministry. He is also involved in several editorial board of scientific journals and an active reviewer of manuscript for various scientific journals.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Molecular Neurobiology, PhD, Imperial College London
1 Oct 1979 → 20 Aug 1983
Award Date: 20 Aug 1983
Neurobiology, Dip. Imperial College, Imperial College London
1 Oct 1979 → 20 Aug 1983
Award Date: 20 Aug 1983
Biochemistry, Bachelor of Science (Hons), University of Bristol
1 Oct 1976 → 30 Jun 1979
Award Date: 31 Jul 1979
Research area keywords
- Neurotoxicology
- Proteomics
- Venomics (Snake venom) and Anti-venomics
- Natural compounds
Collaborations and top research areas from the last five years
-
Mechanistic studies on the cytoprotective potential of yttrium oxide nanoparticles against 6-hydroxydopamine-induced cellular model of Parkinson?s disease
Kim San, T., Ng, K. Y., Othman, I. & Teng, W. D.
1/11/20 → 30/04/25
Project: Research
-
Induction of Apoptosis and Identification of Molecular Pathways and Molecular Targets in Human Lung Cancer Cells Treated by a Selected Synthetic Diarylpentanoid
Naidu, R., Abas, F., Kia Fatt, Q. & Othman, I.
1/11/20 → 30/04/23
Project: Research
-
QSAR-guided, molecular diversity oriented synthesis and evaluation of 1,3,5-triazine derivatives as potent and selective anticancer agents
Dolzhenko, A. V., Tiekink, E. R. T., Chuah, A., Othman, I. & Lim, S. W.
1/11/20 → 30/04/24
Project: Research
-
Behavioural, genomics and proteomic approach to examine Alzheimer's disease in zebrafish
Siddiqui, A., Abidin, S. A. Z., Shah, Z. A., Othman, I. & Kumari, Y., Sept 2023, In: Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology. 271, 17 p., 109636.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile2 Citations (Scopus) -
Rosmarinic acid-rich ethanolic extract of Orthosiphon stamineus ameliorates cognitive and hippocampal long-term potentiation in chronic cerebral hypoperfusion rat model
Hassan, Z., Kumaran, K. R., Chear, N. J. Y., Bakar, S. N. S., Retinasamy, T., Bhuvanendran, S., Majeed, A. M. A., Shaikh, M. F. & Othman, I., 27 Aug 2023, In: Neuroscience Research Notes. 6, 3, 16 p., 196.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile -
Comparative Proteomic Analysis of the Venoms from the Most Dangerous Scorpions in Morocco: Androctonus mauritanicus and Buthus occitanus
Hilal, I., Khourcha, S., Safi, A., Hmyene, A., Asnawi, S., Othman, I., Stöcklin, R. & Oukkache, N., 5 May 2023, In: Life. 13, 5, 17 p., 1133.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile5 Citations (Scopus) -
Analysis of illicit drugs in municipal wastewater using LC-MS/MS: a method validation study
Izani, M. A., Sabri, N. A., Hamidon, N. N., Khaw, K. Y., Othman, I., Mueller, J. & Tay, J. H., 2023, In: Malaysian Journal of Analytical Sciences. 27, 1, p. 1-7 7 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
Flavonoids as receptor tyrosine kinase inhibitors in lung cancer
Sudhesh Dev, S., Farghadani, R., Zainal Abidin, S. A., Othman, I. & Naidu, R., Nov 2023, In: Journal of Functional Foods. 110, 22 p., 105845.Research output: Contribution to journal › Review Article › Research › peer-review
Open AccessFile5 Citations (Scopus)
Prizes
-
2017 Bronze medal at PECIPTA
Shaikh, Farooq (Recipient), Pillai, B Saatheeyavaane Bhuvanendran (Recipient), Kumari, Yatinesh (Recipient), Othman, Iekhsan (Recipient) & Ahemad, Nafees (Recipient), 2017
Prize: Prize (including medals and awards)
-
2018 Silver medal at ITEX
Othman, Iekhsan (Recipient), Shaikh, Farooq (Recipient), Retinasamy, Thaarvena (Recipient), Choo, Brandon Kar Meng (Recipient), Kumari, Yatinesh (Recipient), Hassan, Zurina (Recipient) & Majid, Amin Malik Shah Abdul (Recipient), 2018
Prize: Prize (including medals and awards)
-
NIH Grant: Monash Obesity-Diabetes Intervention (MODI) Study: A 16-week, multicenter, prospective, randomize, open-labeled, parallel, 3-arm controlled trial of metabolic response in the treatment of Type 2 diabetes mellitus with concomitant obesity management.
Zain, Dato’ Anuar Zaini Md (Recipient), Kia Fatt, Quek (Recipient), Ahmad, Badariah (Recipient), Hussain, Nik Asmah Nik (Recipient), Haque, Shamsul (Recipient), Othman, Iekhsan (Recipient), Chen, Robert (Recipient), Pendek, Rokiah (Recipient), Kadir, Khalid (Recipient), Isa, Siti Harnida Md (Recipient), Hassan, Muniarti (Recipient), Ong, Victor Yek Cheng (Recipient), Manderson, Lenore (Recipient) & Oldenburg, Brian (Recipient), 20 May 2008
Prize: Prize (including medals and awards)
Activities
-
Toxicon (Journal)
Iekhsan Othman (Peer reviewer)
30 Sept 2024Activity: Publication peer-review and editorial work types › Peer review responsibility
-
Optimisation of bioflavonoid extraction from Alternanthera sessilis using response surface methodology and its effect on cellular lipidomes in fatty liver disease Kong Kin Weng, Iekhsan Othman, Syafiq Asnawi, Azlina Leong
Iekhsan Othman (Member)
9 Jan 2024Activity: External Academic Engagement › Grant review responsibilities
-
Introduction to LCMS WorkshopMUM Proteomics and Metabolomics PlatformInstrumentation, Sample Preparation and DataAnalysis
Iekhsan Othman (Organiser)
25 Jun 2024 → 26 Jun 2024Activity: Participating in or organising an event types › Contribution to workshop, seminar, course
-
Histology and Histopathology (Journal)
Iekhsan Othman (Peer reviewer)
20 Feb 2024Activity: Publication peer-review and editorial work types › Peer review responsibility
-
Reviewer for Promotion for Dr.Nafees Ahmed Mohd Yunus
Iekhsan Othman (Reviewer)
26 Nov 2024Activity: External Academic Engagement › Peer review panel or committee