Projects per year
Personal profile
Research interests
My research relates to understanding the neurobiology of acquired epilepsy using preclinical models specially focusing on Brain inflammation. My goal is to applying imaging techniques to measure brain inflammation as biomarker for predicting development of epilepsy following a brain insult. In addition, I aim to apply pharmacological and genetic techniques to modify brain inflammation as a strategy to inhibit development of epilepsy post-brain insult.
External positions
Research Fellow, University of Melbourne
3 Apr 2017 → …
Research area keywords
- Neurobiology
- Epilepsy
- Brain inflammation
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 5 Finished
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NHMRC Equipment Grant - Lateral Fluid Percussion Injury (LFPI) Device
Vivash, L. (Primary Chief Investigator (PCI)), Leung, J. (Chief Investigator (CI)), Casillas-Espinosa, P. (Chief Investigator (CI)), Ali, I. (Chief Investigator (CI)), O'Brien, T. (Chief Investigator (CI)), Shultz, S. (Chief Investigator (CI)) & Jones, N. (Chief Investigator (CI))
1/11/23 → 31/12/24
Project: Research
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Translational platform for epilepsy therapy and biomarker discovery
Galanopoulou, A. (Primary Chief Investigator (PCI)), Moshe, S. (Chief Investigator (CI)), Mowrey, W. B. (Chief Investigator (CI)), Branch, C. (Chief Investigator (CI)), Fleysher, R. (Chief Investigator (CI)), Cui , M.-H. (Chief Investigator (CI)), Staba, R. (Chief Investigator (CI)), Mazarati, A. (Chief Investigator (CI)), Sankar, R. (Chief Investigator (CI)), Agoston, D. (Chief Investigator (CI)), Duncan, D. (Chief Investigator (CI)), Cabeen, R. (Chief Investigator (CI)), Coles, L. D. (Chief Investigator (CI)), O'Brien, T. (Chief Investigator (CI)), Toga, A. (Chief Investigator (CI)), Bragin, A. (Chief Investigator (CI)), Engel, J. (Chief Investigator (CI)), Vespa, P. (Chief Investigator (CI)), Harris, N. (Chief Investigator (CI)), Wright, D. (Chief Investigator (CI)), Jones, N. (Chief Investigator (CI)), Shultz, S. (Chief Investigator (CI)), Casillas-Espinosa, P. (Chief Investigator (CI)), Hudson, M. (Chief Investigator (CI)), Ali, I. (Chief Investigator (CI)) & Braine, E. (Associate Investigator (AI))
NIH - National Institutes of Health (United States of America)
15/04/22 → 31/03/26
Project: Research
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Measuring inflammation in brain and blood for predicting risk of post-traumatic epilepsy
Ali, I. (Primary Chief Investigator (PCI)), Jones, N. (Supervisor), O'Brien, T. (Supervisor), Dedeurwaerdere, S. (Chief Investigator (CI)), Wright, D. (Chief Investigator (CI)) & Vivash, L. (Chief Investigator (CI))
United States Department of Defense (DOD)
30/09/21 → 29/06/24
Project: Research
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Testing of the effect of E2730 treatment on multimodality in-vivo biomarkers of GABAergic function in healthy rats and preclinical chronic epilepsy models
O'Brien, T. (Primary Chief Investigator (PCI)), Kwan, P. (Chief Investigator (CI)), Ali, I. (Chief Investigator (CI)), Casillas-Espinosa, P. (Chief Investigator (CI)), Jones, N. (Chief Investigator (CI)), Jupp, B. (Chief Investigator (CI)), Vivash, L. (Chief Investigator (CI)), Wright, D. (Chief Investigator (CI)), Mychasiuk, R. (Chief Investigator (CI)) & Major, B. (Chief Investigator (CI))
Eisai Inc (United States of America)
22/10/20 → 21/10/21
Project: Research
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Polarization of immune cells by novel compounds
Ali, I. (Primary Chief Investigator (PCI)), Jones, N. (Chief Investigator (CI)), Monif, M. (Chief Investigator (CI)) & Semple, B. (Chief Investigator (CI))
Katholieke Universiteit Leuven (KU Leuven) (Catholic University of Leuven)
13/07/20 → 12/09/21
Project: Research
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A pre-existing chronic Toxoplasma gondii infection promotes epileptogenesis and neuropathology in a mouse model of mesial temporal lobe epilepsy
Baker, T. L., Wright, D. K., Thergarajan, P., Uboldi, A. D., Vo, A., Wilson, T., Tonkin, C. J., O'Brien, T. J., Antonic-Baker, A., Asmussen, M. J., McDonald, S. J., Casillas-Espinosa, P. M., Jones, N. C., Ali, I., Sun, M. & Shultz, S. R., Aug 2025, In: Brain, Behavior, and Immunity. 128, p. 440-455 16 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access6 Link opens in a new tab Citations (Scopus) -
Cardiac structural and molecular alterations in rodent models of temporal lobe epilepsy
Liu, Z. (Leading Author), Sivathamboo, S., Thergarajan, P., Gomes, F. M., Ali, I., Powell, K. L., Perucca, P., Jones, N. C., O'Brien, T. J. & Casillas-Espinosa, P. (Leading Author), Jun 2025, In: Epilepsia Open. 10, 3, p. 809-821 13 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access3 Link opens in a new tab Citations (Scopus) -
Clioquinol as a new therapy in epilepsy: From preclinical evidence to a proof-of-concept clinical study
Thevissen, K., Ny, A., Copmans, D., Tits, J., Kamata, K., Gielis, E., Longin, K., Sourbron, J., Thergarajan, P., Tan, T. H. L., Ali, I., Jones, N. C., O'Brien, T. J., Monif, M., Semple, B. D., Germeys, C., Frizzi, B., Minniti, V., Perrone, S. & Linster, C. L. & 6 others, , Oct 2025, In: Epilepsia. 66, 10, p. 3769-3784 16 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access5 Link opens in a new tab Citations (Scopus) -
Ligand-receptor interactions: A key to understanding microglia and astrocyte roles in epilepsy
Thergarajan, P., O'Brien, T. J., Jones, N. C. & Ali, I., Feb 2025, In: Epilepsy & Behavior. 163, 13 p., 110219.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access9 Link opens in a new tab Citations (Scopus) -
Plasma microRNAs as prognostic biomarkers for development of severe epilepsy after experimental traumatic brain injury—EpiBioS4Rx Project 1 study
Heiskanen, M., Ndode-Ekane, X. E., Ali, I., Santana-Gomez, C., Puhakka, N., Gupta, S. D., Andrade, P., Immonen, R., Casillas-Espinosa, P., Manninen, E., Smith, G., Brady, R. D., Silva, J., Braine, E., Hudson, M., Yamakawa, G. R., Jones, N. C., Shultz, S. R., Harris, N. G. & Wright, D. K. & 4 others, , Mar 2025, In: Epilepsia. 205, p. 870-885 16 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access14 Link opens in a new tab Citations (Scopus)
Prizes
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GIN hub funding of $25,000 for project titled 'Role of granulocyte-colony-stimulating factor signalling in epilepsy'
Ali, I. (Recipient) & Tsantikos, E. (Recipient), 2022
Prize: Prize (including medals and awards)
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M2 Polarization of microglia as a new approach targeting temporal lobe epilepsy
Ali, I. (Recipient), 2017
Prize: Competitive Fellowships