Projects per year
Personal profile
Research interests
My research relates to understanding the neurobiology of acquired epilepsy using preclinical models specially focusing on Brain inflammation. My goal is to applying imaging techniques to measure brain inflammation as biomarker for predicting development of epilepsy following a brain insult. In addition, I aim to apply pharmacological and genetic techniques to modify brain inflammation as a strategy to inhibit development of epilepsy post-brain insult.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
External positions
Research Fellow, University of Melbourne
3 Apr 2017 → …
Research area keywords
- Neurobiology
- Epilepsy
- Brain inflammation
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Measuring inflammation in brain and blood for predicting risk of post-traumatic epilepsy
Ali, I., Jones, N., O'Brien, T., Dedeurwaerdere, S., Wright, D. & Vivash, L.
United States Department of Defense (DOD)
30/09/21 → 30/09/24
Project: Research
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Translational platform for epilepsy therapy and biomarker discovery
Galanopoulou, A. S., Moshe, S., Mowrey, W., Branch, C., Fleysher, R., Cui , M., Staba, R. J., Mazarati, A., Sankar, R., Agoston, D., Duncan, D., Cabeen, R., Coles, L., O'Brien, T., Toga, A. W., Bragin, A., Engel, J., Vespa, P., Harris, N., Wright, D., Jones, N., Shultz, S., Casillas-Espinosa, P., Hudson, M., Ali, I. & Braine, E.
NIH - National Institutes of Health (United States of America)
15/04/22 → 31/03/23
Project: Research
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Testing of the effect of E2730 treatment on multimodality in-vivo biomarkers of GABAergic function in healthy rats and preclinical chronic epilepsy models
O'Brien, T., Kwan, P., Ali, I., Casillas-Espinosa, P., Jones, N., Jupp, B., Vivash, L., Wright, D., Mychasiuk, R. & Major, B.
22/10/20 → 21/10/21
Project: Research
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Polarization of immune cells by novel compounds
Ali, I., Jones, N., Monif, M. & Semple, B.
Katholieke Universiteit Leuven (KU Leuven) (Catholic University of Leuven)
13/07/20 → 12/09/21
Project: Research
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E2730, an uncompetitive γ-aminobutyric acid transporter-1 inhibitor, suppresses epileptic seizures in a rat model of chronic mesial temporal lobe epilepsy
Ali, I., Silva, J., Casillas-Espinosa, P. M., Braine, E., Yamakawa, G. R., Hudson, M. R., Brady, R. D., Major, B., Thergarajan, P., Haskali, M. B., Wright, D. K., Jupp, B., Vivash, L., Shultz, S. R., Mychasiuk, R., Kwan, P., Jones, N. C., Fukushima, K., Sachdev, P., Cheng, J. Y., & 1 others, 2023, (Accepted/In press) In: Epilepsia. 12 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Early preclinical plasma protein biomarkers of brain trauma are influenced by early seizures and levetiracetam
Saletti, P. G., Mowrey, W. B., Liu, W., Li, Q., McCullough, J., Aniceto, R., Lin, I. H., Eklund, M., Casillas-Espinosa, P. M., Ali, I., Santana-Gomez, C., Coles, L., Shultz, S. R., Jones, N., Staba, R., O'Brien, T. J., Moshé, S. L., Agoston, D. V., Galanopoulou, A. S. & for the EpiBioS4Rx Study Group, Jun 2023, In: Epilepsia Open. 8, 2, p. 586-608 23 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Image data harmonization tools for the analysis of post-traumatic epilepsy development in preclinical multisite MRI studies
Bhagavatula, S., Cabeen, R., Harris, N. G., Gröhn, O., Wright, D. K., Garner, R., Bennett, A., Alba, C., Martinez, A., Ndode-Ekane, X. E., Andrade, P., Paananen, T., Ciszek, R., Immonen, R., Manninen, E., Puhakka, N., Tohka, J., Heiskanen, M., Ali, I., Shultz, S. R., & 13 others, Sept 2023, In: Epilepsy Research. 195, 6 p., 107201.Research output: Contribution to journal › Article › Research › peer-review
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Levetiracetam Pharmacokinetics and Brain Uptake in a Lateral Fluid Percussion Injury Rat Model
Coles, L. D., Saletti, P. G., Lisgaras, C. P., Casillas-Espinosa, P. M., Liu, W., Li, Q., Jones, N. C., Shultz, S., Ali, I., Brady, R., Yamakawa, G., Hudson, M., Silva, J., Braine, E., Mishra, U., Cloyd, J. C., O'Brien, T. J., Moshé, S. L., Galanopoulou, A. S. & EpiBioS4Rx Study Group, 1 Aug 2023, In: Journal of Pharmacology and Experimental Therapeutics. 386, 2, p. 259-265 7 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Neuroinflammation: A Common Pathway in Alzheimer's Disease and Epilepsy
Liaw, Y., Retinasamy, T., Arulsamy, A., Ali, I., Jones, N. C., O'Brien, T. J. & Shaikh, M. F., 25 Jul 2023, In: Journal of Alzheimer's Disease. 94, s1, p. S253-S265 13 p.Research output: Contribution to journal › Review Article › Research › peer-review
Open AccessFile1 Citation (Scopus)
Prizes
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GIN hub funding of $25,000 for project titled 'Role of granulocyte-colony-stimulating factor signalling in epilepsy'
Ali, Idrish (Recipient) & Tsantikos, Evelyn (Recipient), 2022
Prize: Prize (including medals and awards)
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M2 Polarization of microglia as a new approach targeting temporal lobe epilepsy
Ali, Idrish (Recipient), 2017
Prize: Competitive Fellowships