Projects per year
Personal profile
Research interests
My research relates to understanding the neurobiology of acquired epilepsy using preclinical models specially focusing on Brain inflammation. My goal is to applying imaging techniques to measure brain inflammation as biomarker for predicting development of epilepsy following a brain insult. In addition, I aim to apply pharmacological and genetic techniques to modify brain inflammation as a strategy to inhibit development of epilepsy post-brain insult.
External positions
Research Fellow, University of Melbourne
3 Apr 2017 → …Network
Recent external collaboration on country level. Dive into details by clicking on the dots or
Projects
- 2 Active
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Testing of the effect of E2730 treatment on multimodality in-vivo biomarkers of GABAergic function in healthy rats and preclinical chronic epilepsy models
O'Brien, T., Kwan, P., Ali, I., Casillas-Espinosa, P., Jones, N., Jupp, B., Vivash, L., Wright, D., Mychasiuk, R. & Major, B.
22/10/20 → 21/10/21
Project: Research
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Polarization of immune cells by novel compounds
Ali, I., Jones, N., Monif, M. & Semple, B.
13/07/20 → 12/09/21
Project: Research
Research output
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Microglial polarization in posttraumatic epilepsy: Potential mechanism and treatment opportunity
Therajaran, P., Hamilton, J. A., O'Brien, T. J., Jones, N. C. & Ali, I., Feb 2020, In: Epilepsia. 61, 2, p. 203-215 13 p.Research output: Contribution to journal › Review Article › Research › peer-review
4 Citations (Scopus) -
Neurodegenerative pathways as targets for acquired epilepsy therapy development
Casillas-Espinosa, P. M., Ali, I. & O'Brien, T. J., 1 Jun 2020, In: Epilepsia Open. 5, 2, p. 138-154 17 p.Research output: Contribution to journal › Review Article › Research › peer-review
Open AccessFile1 Citation (Scopus) -
Cav3.2 T-type calcium channel mutation influences kindling-induced thalamic neuronal firing patterns in Genetic Absence Epilepsy Rats From Strasbourg
Çarçak, N., Ali, I., Powell, K., Zheng, T., Onat, F. & O'Brien, T. J., Jul 2019, In: Epilepsia. 60, 7, p. 1378-1386 9 p.Research output: Contribution to journal › Article › Research › peer-review
1 Citation (Scopus) -
Harmonization of lateral fluid-percussion injury model production and post-injury monitoring in a preclinical multicenter biomarker discovery study on post-traumatic epileptogenesis
Ndode-Ekane, X. E., Santana-Gomez, C., Casillas-Espinosa, P. M., Ali, I., Brady, R. D., Smith, G., Andrade, P., Immonen, R., Puhakka, N., Hudson, M. R., Braine, E. L., Shultz, S. R., Staba, R. J., O'Brien, T. J. & Pitkänen, A., 1 Mar 2019, In: Epilepsy Research. 151, p. 7-16 10 p.Research output: Contribution to journal › Article › Research › peer-review
8 Citations (Scopus) -
Harmonization of pipeline for detection of HFOs in a rat model of post-traumatic epilepsy in preclinical multicenter study on post-traumatic epileptogenesis
Santana-Gomez, C., Andrade, P., Hudson, M. R., Paananen, T., Ciszek, R., Smith, G., Ali, I., Rundle, B. K., Ndode-Ekane, X. E., Casillas-Espinosa, P. M., Immonen, R., Puhakka, N., Jones, N., Brady, R. D., Perucca, P., Shultz, S. R., Pitkänen, A., O'Brien, T. J. & Staba, R., Oct 2019, In: Epilepsy Research. 156, 8 p., 106110.Research output: Contribution to journal › Article › Research › peer-review
7 Citations (Scopus)
Prizes
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M2 Polarization of microglia as a new approach targeting temporal lobe epilepsy
Ali, Idrish (Recipient), 2017
Prize: Competitive Fellowships