20082020

Research output per year

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Personal profile

Research interests

My research relates to understanding the neurobiology of acquired epilepsy using preclinical models specially focusing on Brain inflammation. My goal is to applying imaging techniques to measure brain inflammation as biomarker for predicting development of epilepsy following a brain insult. In addition, I aim to apply pharmacological and genetic techniques to modify brain inflammation as a strategy to inhibit development of epilepsy post-brain insult. 

External positions

Research Fellow, University of Melbourne

3 Apr 2017 → …

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Research Output

Microglial polarization in posttraumatic epilepsy: Potential mechanism and treatment opportunity

Therajaran, P., Hamilton, J. A., O'Brien, T. J., Jones, N. C. & Ali, I., Feb 2020, In : Epilepsia. 61, 2, p. 203-215 13 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

1 Citation (Scopus)

Neurodegenerative pathways as targets for acquired epilepsy therapy development

Casillas-Espinosa, P. M., Ali, I. & O'Brien, T. J., 1 Jun 2020, In : Epilepsia Open. 5, 2, p. 138-154 17 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
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Cav3.2 T-type calcium channel mutation influences kindling-induced thalamic neuronal firing patterns in Genetic Absence Epilepsy Rats From Strasbourg

Çarçak, N., Ali, I., Powell, K., Zheng, T., Onat, F. & O'Brien, T. J., Jul 2019, In : Epilepsia. 60, 7, p. 1378-1386 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Harmonization of lateral fluid-percussion injury model production and post-injury monitoring in a preclinical multicenter biomarker discovery study on post-traumatic epileptogenesis

Ndode-Ekane, X. E., Santana-Gomez, C., Casillas-Espinosa, P. M., Ali, I., Brady, R. D., Smith, G., Andrade, P., Immonen, R., Puhakka, N., Hudson, M. R., Braine, E. L., Shultz, S. R., Staba, R. J., O'Brien, T. J. & Pitkänen, A., 1 Mar 2019, In : Epilepsy Research. 151, p. 7-16 10 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Harmonization of pipeline for detection of HFOs in a rat model of post-traumatic epilepsy in preclinical multicenter study on post-traumatic epileptogenesis

Santana-Gomez, C., Andrade, P., Hudson, M. R., Paananen, T., Ciszek, R., Smith, G., Ali, I., Rundle, B. K., Ndode-Ekane, X. E., Casillas-Espinosa, P. M., Immonen, R., Puhakka, N., Jones, N., Brady, R. D., Perucca, P., Shultz, S. R., Pitkänen, A., O'Brien, T. J. & Staba, R., Oct 2019, In : Epilepsy Research. 156, 8 p., 106110.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)