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Personal profile

Biography

Ian is a Research Fellow in the Drug Delivery, Disposition and Dynamics (D4) department at the Monash Institute of Pharmaceutical Sciences (MIPS).

He completed his undergraduate studies at RMIT University, graduating in 2012 with a BSc in Environmental Science and later in 2013 with a BSc in Applied Science (honours) He later completed his PhD in lymphatic drug delivery at MIPS in 2019, under the supervision of Professor Michelle McIntosh and Professor Christopher Porter.

During his PhD Ian’s research focused on the enzyme recombinant human hyaluronidase (rHuPH20), which is utilised in translating intravenously administered therapies to the simpler and safer method of interstitially (e.g. subcutaneously) delivery. The findings from Ian’s PhD developed a greater understanding of how co- and pre-administered rHuPH20 can impact the systemic and lymphatic absorption mechanisms of interstitially administered monoclonal antibodies and nanoparticles.

Ian’s expertise and continued research interest in lymphatic drug delivery has seen him continue on as research fellow at MIPS, working closely with Dr Natalie Trevaskis. His research aims to understand the extent of lymphatic absorption and exposure of established and emerging drugs and drug delivery technologies, to further improve our fundamental understanding of the role the lymphatic system has both in health and disease.

Education/Academic qualification

Applied Science, BSc Applied Science (Honours), RMIT University

2013

Environmental science, BSc Environmental Science, RMIT University

20102012

Keywords

  • Lymphatic Drug Transport
  • Interstitial Drug Delivery
  • Drug delivery

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Research Output 2018 2018

Elucidation of the pharmacokinetic/pharmacodynamic determinants of fosfomycin activity against Pseudomonas aeruginosa using a dynamic in vitro model

Bilal, H., Peleg, A. Y., McIntosh, M. P., Styles, I. K., Hirsch, E. B., Landersdorfer, C. B. & Bergen, P. J., 1 Jun 2018, In : Journal of Antimicrobial Chemotherapy. 73, 6, p. 1570-1578 9 p.

Research output: Contribution to journalArticleResearchpeer-review