• 19 Innovation Walk, Clayton Campus, Monash University

    3800 Melbourne


Accepting PhD Students

1996 …2022
If you made any changes in Pure these will be visible here soon.

Personal profile


Dr Ian Smyth is a Fellow at Monash University in Melbourne, Australia. His research interests centre on understanding the developmental mechanisms which shape the differentiation of epithelia in the mouse embryo. His group principally employs mouse genetics to identify novel factors which contribute to development of the skin and kidney, with a focus on animals models of human disease. Recent studies have also included the application of imaging and image analysis to provide insights into branching morphogenesis during organ development. He was awarded his PhD from the University of Queensland in 1999 and undertook postdoctoral training as a Wellcome Trust Traveling Research Fellow at the MRC Human Genetics Unit (Edinburgh) and Baylor College of Medicine (Houston). After a stint in London as an LRI Fellow at Cancer Research UK he returned to Australia in 2006 as an NHMRC RD Wright Fellow to establish his own laboratory in Melbourne.

Research area keywords

  • Congenital Disease
  • Skin and Kidney Development

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2006 2022

The cellular basis of branching morphogenesis during kidney development

Smyth, I., Combes, A., Fernandez-Gonzalez, R. & McNeill, H.


Project: Research

Applying functional genomics to kidney disease

Smyth, I., Little, M., Simons, C., Mallett, A. & Alexander, S. I.


Project: Other

Research Output 1996 2019

Cellular and molecular determinants of normal and abnormal kidney development

Tham, M. S. & Smyth, I. M., 1 Mar 2019, In : Wiley Interdisciplinary Reviews: Developmental Biology. 8, 2, 16 p., e338.

Research output: Contribution to journalArticleResearchpeer-review

Morphogenesis of the kidney and lung requires branch-tip directed activity of the Adamts18 metalloprotease

Rutledge, E. A., Parvez, R. K., Short, K. M., Smyth, I. M. & McMahon, A. P., 15 Oct 2019, In : Developmental Biology. 454, 2, p. 156-169 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Seminars in cell and developmental biology

Smyth, I. M. & Bertram, J. F., Jul 2019, In : Seminars in Cell and Developmental Biology. 91, p. 84-85 2 p.

Research output: Contribution to journalEditorialOtherpeer-review

Branching morphogenesis in the developing kidney 1 is not impacted by nephron formation or integration

Short, K. M., Combes, A. N., Lisnyak, V., Lefevre, J. G., Jones, L. K., Little, M. H., Hamilton, N. A. & Smyth, I. M., 31 Jul 2018, In : eLife. 7, 11 p., e38992.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Haploinsufficiency for the Six2 gene increases nephron progenitor proliferation promoting branching and nephron number

Combes, A. N., Wilson, S., Phipson, B., Binnie, B. B., Ju, A., Lawlor, K. T., Cebrian, C., Walton, S. L., Smyth, I. M., Moritz, K. M., Kopan, R., Oshlack, A. & Little, M. H., Mar 2018, In : Kidney International. 93, 3, p. 589-598 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Press / Media