Ian Smith

Professor

1985 …2020
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Research Output 1985 2019

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1994

A stable leukocyte-derived factor inhibits platelet aggregation

Liu, J. J., Xie, B., Smith, I. L., Johnston, C. I. & Buxton, B. F., 15 Jun 1994, In : Biochemical and Biophysical Research Communications. 201, 2, p. 878-882 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Characterization of Membrane‐Associated Peptidase Activities Expressed by Endothelial Cells of the Ovine Median Eminence

Lew, R. A., Tetaz, T. & Smith, A. I., 1 Jan 1994, In : Journal of Neuroendocrinology. 6, 2, p. 225-232 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Evidence for a two-step mechanism of gonadotropin-releasing hormone metabolism by prolyl endopeptidase and metalloendopeptidase EC 3.4.24.15 in ovine hypothalamic extracts

Lew, R. A., Tetaz, T. J., Glucksman, M. J., Roberts, J. L. & Smith, A. I., 29 Apr 1994, In : Journal of Biological Chemistry. 269, 17, p. 12626-12632 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Pharmacological characterization of linear analogues of vasopressin generated by the systematic substitution of positions 1 and 6 by l-amino acids

Howl, J., Filer, A. D. J., Parslow, R. A., Kirk, C. J., Jurzak, M., Smith, A. I. & Wheatley, M., 29 Apr 1994, In : Biochemical Pharmacology. 47, 9, p. 1497-1501 5 p.

Research output: Contribution to journalArticleResearchpeer-review

The role of EC 3.4.24.15 in the post-secretory regulation of peptide signals

Smith, A. I., Tetaz, T., Roberts, J. L., Glucksman, M., Clarke, I. J. & Lew, R. A., 1 Jan 1994, In : Biochimie. 76, 3-4, p. 288-294 7 p.

Research output: Contribution to journalArticleResearchpeer-review

1993

Characterization of immunoreactive AVP in the ovine hypothalamo-pituitary axis

Shen, P. J., Clarke, I. J., Funder, J. W. & Smith, A. I., 1 Jan 1993, In : Peptides. 14, 4, p. 815-820 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Identification and characterization of an amidating enzyme in ovine heart

Lew, R. A. & Smith, A. I., 1 Jan 1993, In : Clinical and Experimental Pharmacology and Physiology. 20, 4, p. 231-238 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Many peptides that are present in the external zone of the median eminence are not secreted into the hypophysial portal blood of sheep

Clarke, I., Jessop, D., Millar, R., Morris, M., Bloom, S., Lightman, S., Coen, C. W., Lew, R. & Smith, I., 1 Jan 1993, In : Neuroendocrinology. 57, 5, p. 765-775 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Monoclonal antibodies to arginine vasopressin receptor bind to liver, kidney and pituitary membranes

Trinder, D., Mooser, V., Phillips, P. A., Smith, A. I., Casley, D. & Johnston, C. I., 1 Jan 1993, In : Clinical and Experimental Pharmacology and Physiology. 20, 6, p. 443-449 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Ovine anterior pituitary proopiomelanocortin gene expression is not increased by acth secretagogues in vitro

Levin, N., Wallace, C., Bengani, N., Blum, M., Farnworth, P., Smith, A. I. & Roberts, J. L., 1 Jan 1993, In : Endocrinology. 132, 4, p. 1692-1700 9 p.

Research output: Contribution to journalArticleResearchpeer-review

The role of vasopressin on ACTH secretion and biosynthesis in the ovine pituitary gland

Smith, A. I., Levin, N., Wallace, C. A., Farnworth, P., Blum, M. & Roberts, J. L., 29 Apr 1993, In : Regulatory Peptides. 45, 1-2, p. 237-241 5 p.

Research output: Contribution to journalArticleResearchpeer-review

1992

Distribution and characterization of peptidylglycine α-amidating monooxygenase activity in the ovine brain and hypothalamo-pituitary axis

Lew, R. A., Clarke, I. J. & Smith, A. I., 1 Jan 1992, In : Endocrinology. 130, 2, p. 994-1000 7 p.

Research output: Contribution to journalArticleResearchpeer-review

1991

Distribution, Isolation and Sequence Analysis of the C‐Terminal Heptapeptide of Pro‐Enkephalin A (YGGFMRF) from the Ovine Median Eminence

Giraud, A. S., Clarke, I. J., Rundle, S. E., Parker, L. M., Funder, J. W., Simpson, R. J. & Smith, A. I., 1 Jan 1991, In : Journal of Neuroendocrinology. 3, 2, p. 215-220 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Identification of a non-covalent oxytocin neurophysin-I complex in the bovine ovary

Shukovski, L., Findlay, J. K. & Smith, A. I., 1 Jan 1991, In : Journal of Endocrinology. 128, 2, p. 305-314 10 p.

Research output: Contribution to journalArticleResearchpeer-review

The interaction of a huntington disease factor with receptors for the neurotoxin kainic acid

Dodd, P. R., Watson, W. E. J., Morrison, M. M., Johnston, G. A. R., Smith, A. I., Ruwoldt, A. & Walls, R. S., 1 Dec 1991, In : Metabolic Brain Disease. 6, 4, p. 213-224 12 p.

Research output: Contribution to journalArticleResearchpeer-review

1990

Arginine vasopressin and corticotropin releasing factor: Binding to ovine anterior pituitary membranes

Shen, P. J., Clarke, I. J., Canny, B. J., Funder, J. W. & Smith, A. I., 1 Jan 1990, In : Endocrinology. 127, 5, p. 2085-2089 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Morphine decreases lh secretion in ovariectomized ewes only after steroid priming and not by direct pituitary action

Horton, R. J. E., Li, J. Y., Cummins, J. T., Smith, A. I., Shen, P. J. & Clarke, L. J., 1 Jan 1990, In : Neuroendocrinology. 52, 6, p. 612-617 6 p.

Research output: Contribution to journalArticleResearchpeer-review

1989

Arginine vasopressin is a much more potent stimulus to acth release from ovine anterior pituitary cells than ovine corticotropin-releasing factor: 1. In vitro studies

Familari, M., Smith, A. I., Smith, R. & Funder, J. W., 1 Jan 1989, In : Neuroendocrinology. 50, 2, p. 152-157 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Dopaminergic agents differentially regulate both processing and content of α-N-acetylated endorphin and α-MSH in the ovine pituitary intermediate lobe

Smith, A. I., Wallace, C. A., Clarke, L. J. & Fitnder, J. W., 1 Jan 1989, In : Neuroendocrinology. 49, 5, p. 545-550 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Generation of met-enkephalin arg6phe7 immunoreactivity by proteolytic cleavage of mammalian plasma precursors by pepsin

Giraud, A. S., Parker, L., Reichman, C., Familari, M., Smith, A. I. & Funder, J., 1 Jan 1989, In : Endocrinology. 124, 4, p. 1711-1716 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Gonadal steroids and anterior lobe dynorphin in the male rat

Fullerton, M. J., Smith, A. I., Clements, J. A. & Funder, J. W., 1 Jan 1989, In : Journal of Steroid Biochemistry. 32, 2, p. 303-308 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Immunocytochemical demonstration of mineralocorticoid receptors in rat and human kidney

Rundle, S. E., Smith, A. I., Stockman, D. & Funder, J. W., 1 Jan 1989, In : Journal of Steroid Biochemistry. 33, 6, p. 1235-1242 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Immunolocalization of renal mineralocorticoid receptors with an antiserum against a peptide deduced from the complementary deoxyribonucleic acid sequence

Krozowski, Z. S., Rundle, S. E., Wallace, C., Castell, M. J., Shen, J. H., Dowling, J., Funder, J. W. & Smith, A. I., 1 Jan 1989, In : Endocrinology. 125, 1, p. 192-198 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Stress‐Related Changes in β‐Endorphin Processing: The Limitations of Slaughterhouse Material

Smith, A. I., Wallace, C. A., Clarke, I. J. & Funder, J. W., 1 Jan 1989, In : Journal of Neuroendocrinology. 1, 5, p. 357-362 6 p.

Research output: Contribution to journalArticleResearchpeer-review

1988

Angiotensin II-stimulated phosphatidylinositol turnover in rat adrenal glomerulosa cells has a complex dependence on calcium

Woodcock, E. A., Smith, A. I. & Schmauk White, L. B., 1 Mar 1988, In : Endocrinology. 122, 3, p. 1053-1059 7 p.

Research output: Contribution to journalArticleResearchpeer-review

An unusual phosphatidylinositol turnover pathway in noradrenaline-perfused rat hearts

Woodcock, E. A., Smith, A. I., Wallace, C. A. & White, L. B. S., 1 Jan 1988, In : Clinical and Experimental Pharmacology and Physiology. 15, 4, p. 251-255 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Beta endorphin and dynorphin levels in rat pituitary and hypothalamus: Age studies

Dax, E. M., Reichman, C., Fullerton, M., Wallace, C., Smith, A. I. & Funder, J. W., 1 Jan 1988, In : Neuroendocrinology. 47, 3, p. 241-248 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Effect of myiasis and acute restraint stress on plasma levels of immunoreactive, β-endorphin, adrenocorticotrophin (acth) and cortisol in the sheep

Shutt, D. A., Connell, R., Fell, L. R., Smith, A. I. & Wallace, C. A., 1 Jan 1988, In : Australian Journal of Biological Sciences. 41, 3, p. 297-302 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Immunoreactive dynorphin is regulated by estrogen in the rat anterior pituitary

Fullerton, M. J., Smith, A. I. & Funder, J. W., 1 Jan 1988, In : Neuroendocrinology. 47, 1, p. 1-6 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Mineralocorticoid action: Target tissue specificity is enzyme, not receptor, mediated

Funder, J. W., Pearce, P. T., Smith, R. & Smith, A. I., 1 Jan 1988, In : Science. 242, 4878, p. 583-585 3 p.

Research output: Contribution to journalArticleResearchpeer-review

Post-translational processing of pro-opiomelanocortin in the brattleboro (Di/di) rat pituitary

Canny, B. J., Ian Smith, A., Clements, J. A. & Funder, J. W., 1 Jan 1988, In : Neuroendocrinology. 48, 6, p. 603-610 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Proopiomelanocortin processing in the pituitary, central nervous system, and peripheral tissues

Smith, A. I. & Funder, J. W., 1 Jan 1988, In : Endocrine Reviews. 9, 1, p. 159-179 21 p.

Research output: Contribution to journalArticleResearchpeer-review

Properties of [3h]l-desamino-8-d-arginine vasopressin as a radioligand for vasopressin v2-receptors in rat kidney

Marchingo, A. J., Abrahams, J. M., Woodcock, E. A., Smith, A. I., Mendelsohn, F. A. O. & Johnston, C. I., 1 Apr 1988, In : Endocrinology. 122, 4, p. 1328-1336 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Right atrial dilatation increases inositol-(1,4,5)trisphosphate accumulation Implications for the control of atrial natriuretic peptide release

von Harsdorf, R., Lang, R., Fullerton, M., Smith, A. I. & Woodcock, E. A., 6 Jun 1988, In : FEBS Letters. 233, 1, p. 201-205 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
1987

Evidence for a lack of inositol - (1,4,5)trisphosphate kinase activity in norepinephrine-perfused rat hearts

Woodcock, E. A., Smith, A. I., Wallace, C. A. & White, L. B. S., 14 Oct 1987, In : Biochemical and Biophysical Research Communications. 148, 1, p. 68-77 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Isolation, amino acid sequence and action of guinea-pig ACTH on aldosterone production by glomerulosa cells

Smith, A. I., Wallace, C. A., Moritz, R. L., Simpson, R. J., Schmauk-White, L. B., Woodcock, E. A. & Funder, J. W., 1 Jan 1987, In : Journal of Endocrinology. 115, 2

Research output: Contribution to journalArticleResearchpeer-review

N-Acetylated endorphins in ovine anterior pituitary and neuro-intermediate lobe

Cheng, M. C., Smith, A. I., Clements, J. A. & Funder, J. W., 1 Jan 1987, In : Peptides. 8, 6, p. 1045-1050 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Partial purification from human serum of a specific binding protein for human growth hormone

Herington, A. C., Smith, A. I., Wallace, C. & Stevenson, J. L., 1 Jan 1987, In : Molecular and Cellular Endocrinology. 53, 3, p. 203-209 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Plasma atrial natriuretic peptide: concentrations and circulating forms in normal man and patients with chronic renal failure

Ogawa, K., Smith, A. I., Hodsman, G. P., Jackson, B., Woodcock, E. A. & Johnston, C. I., 1 Jan 1987, In : Clinical and Experimental Pharmacology and Physiology. 14, 2, p. 95-102 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Posttranslational Processing of Corticotropin‐releasing Factor in the Ovine Tuberoinfundibular System and Pituitary

Smith, A. I., Engler, D., Fullerton, M. J. J., Pham, T., Wallace, C., Morgan, F. J., Clarke, I. J. & Funder, J. W., 1 Jan 1987, In : Annals of the New York Academy of Sciences. 512, 1, p. 24-47 24 p.

Research output: Contribution to journalArticleResearchpeer-review

Stimulation of phosphatidylinositol metabolism in the isolated, perfused rat heart

Woodcock, E. A., Schmauk White, L. B., Smith, A. I. & McLeod, J. K., 1 Jan 1987, In : Circulation Research. 61, 5, p. 625-631 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Stress-induced changes in plasma concentrations of immunoreactive β-endorphin and cortisol in response to routine surgical procedures in lambs

Shutt, D. A., Fell, L. R., Connell, R., Bell, A. K., Wallace, C. A. & Smith, A. I., 1 Jan 1987, In : Australian Journal of Biological Sciences. 40, 1, p. 97-104 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Study of receptor-stimulated phosphatidylinositol hydrolysis in intact, perfused rat hearts

Woodcock, E. A., McLeod, J. K., Smith, A. I. & Clark, M. G., 1 Jan 1987, In : Clinical and Experimental Pharmacology and Physiology. 14, 3, p. 209-213 5 p.

Research output: Contribution to journalArticleResearchpeer-review

The combined use of size-exclusion and reversed-phase high-performance liquid chromatography for characterization of β-endorphin processing pathways

Smith, A. I., Wallace, C. A., Cheng, M. C. & Autelitano, D. J., 1 Jan 1987, In : Journal of Chromatography B: Biomedical Sciences and Applications. 416, C, p. 255-264 10 p.

Research output: Contribution to journalArticleResearchpeer-review

1986

Anterior pituitary cells from brattleboro (di/di), long-evans and sprague-dawley rats contain immunoreactive arginine vasopressin

Lolait, S. J., Markwick, A. J., McNally, M., Abraham, J., Ian Smith, A. & Funder, J. W., 1 Jan 1986, In : Neuroendocrinology. 43, 5, p. 577-583 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Elevated plasma levels of pro-opiomelanocortin-derived peptides in sheep following hypothalamo-pituitary disconnection

Clarke, I. J., Clements, J. A., Cummins, J. T., Dench, F., Smith, A. I., Robinson, P. M. & Funder, J. W., 1 Jan 1986, In : Neuroendocrinology. 44, 4, p. 508-514 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Pregnancy-associated changes in ovarian immunoreactive β-endorphin in rats

Autelitano, D. J., Lolait, S. J., Smith, A. I. & Funder, J. W., 1 Jan 1986, In : Journal of Endocrinology. 108, 3, p. 343-350 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Pro-opiomelanocortin messenger ribonucleic acid and posttranslational processing of beta endorphin in spleen macrophages

Lolait, S. J., Clements, J. A., Markwick, A. J., Cheng, C., McNally, M., Smith, A. I. & Funder, J. W., 1 Jan 1986, In : Journal of Clinical Investigation. 77, 6, p. 1776-1779 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

α-N-acetylated β-endorphin is differentially processed in the normal and hypothalamo-pituitary-disconnected (HPD) ewe

Smith, A. I., Wallace, C. A., Autelitano, D. J., Cheng, M. C., Clarke, I. J. & Funder, J. W., 11 Apr 1986, In : Neuroscience Letters. 65, 2, p. 229-233 5 p.

Research output: Contribution to journalArticleResearchpeer-review

β-Endorphin and its congeners in rat pituitary and thyroid: Effects of propylthiouracil and thyroid hormone administration

Cheng, M. C., Smith, A. I. & Funder, J. W., 1 Jan 1986, In : Endocrinology. 119, 2, p. 642-647 6 p.

Research output: Contribution to journalArticleResearchpeer-review