Personal profile


Professor Ian Smith completed his first degree in Newcastle upon Tyne England and moved to Australia in 1984 to complete his PhD at Prince Henrys Institute Melbourne and Monash University. In 1991 Ian moved to the Baker Heart Research Institute and was Associate Director until his move to Monash University in 2004.

Ian is currently Vice-Provost (Research & Research Infrastructure) and has responsibility for the oversight and management of the universities research alliances and research infrastructure as well as developing and implementing strategies to meet future university infrastructure needs in these areas.

Ian is an accomplished medical researcher and is recognized as a leader in his field. His research applies proteomics technologies to study the proteases involved in the generation and metabolism of peptide regulators involved in both brain and cardiovascular function This research has resulted in over 250 publications and many patents. Ian receives regular invitations to speak at international meetings, many as a plenary speaker. His research has had a direct impact on human health and has led to changes in clinical practice. Ian was a co-founder of a proteomics-based, publicly listed, biotechnology company and he continues to collaborate and consult widely with the pharmaceutical and biotechnology industry. Ian serves on six international editorial boards and over the years he has held office-bearing positions in a number of national and international societies and has had an active involvement in the organisation of numerous national and international scientific meetings. Finally, he has held and continues to hold, a variety of national and international senior government and non- government advisory board/committee memberships. 


  • ECE
  • Vascular Peptides
  • Vascular Tone
  • Protease Inhibitors
  • Endothelin
  • Angiotensin
  • ACE
  • Proteomics
  • Proteases
  • Peptides
  • Mass Spectrometry

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2002 2020

Research Output 1995 2017

N-acetylcysteine attenuates the development of cardiac fibrosis and remodeling in a mouse model of heart failure

Giam, B., Chu, P. . Y., Kuruppu, S., Smith, A. I., Horlock, D., Kiriazis, H., Du, X-J., Kaye, D. M. & Rajapakse, N. W. 1 Apr 2016 In : Physiological Reports. 4, 7, 13 p., e12757

Research output: Research - peer-reviewArticle

Open Access

Treatment adherence and its impact on Disease-Free survival in the breast international group 1-98 trial of tamoxifen and letrozole, alone and in sequence

Chirgwin, J. H., Giobbie-Hurder, A., Coates, A. S., Price, K. N., Ejlertsen, B., Debled, M., Gelber, R. D., Goldhirsch, A., Smith, I., Rabaglio, M., Forbes, J. F., Neven, P., Láng, I., Colleoni, M. & Thürlimann, B. 20 Jul 2016 In : Journal of Clinical Oncology. 34, 21, p. 2452-2459 8 p.

Research output: Research - peer-reviewArticle

Changes in protein abundance are observed in bacterial isolates from a natural host

Rees, M. A., Stinear, T. P., Goode, R. J. A., Coppel, R. L., Smith, A. I. & Kleifeld, O. 2015 In : Frontiers in Cellular and Infection Microbiology. 5, (Art. No: 71), p. 1 - 15 15 p.

Research output: Research - peer-reviewArticle