Ian Harding

Dr

Accepting PhD Students

20062021
If you made any changes in Pure these will be visible here soon.

Personal profile

Biography

Dr. Ian Harding is an NHMRC Early Career Research Fellow in the Monash Institute of Cognitive and Clinical Neurosciences (MICCN). He has a background in cognitive neuroscience, and uses functional and structural magnetic resonance imaging (MRI) and positron emission tomography (PET) to investigate brain markers and mechanisms of cognitive functioning and progressive neurodegeneration. He currently has a particular interest in neurological disorders that principally effect the cerebellum and basal ganglia, including Friedreich ataxia and Huntington disease.

He is the Head of the Dementia, Ageing, and Neurodegeneration research stream at MICCN, and the Founding Principal Investigator of the ENIGMA-Ataxia international neuroimaging consortium.

His research includes investigations of:

-       the spreading pattern of functional and structural abnormalities across the brain in progressive neurodegeneration, and the mechanisms that may underpin that spread (e.g., functional diaschisis, anatomical transneuronal degeneration, and chronic neuroinflammation)

-       the complementary roles of the cerebellum and basal ganglia in higher-order cognition (e.g., cognitive control and working memory), and the consequences of degeneration in one to functioning in the other

-       similarities and differences in the spatial profile of brain and spinal degeneration in different forms of cerebellar ataxia

-       the role of large-scale functional brain networks, and dynamic shifts in those networks, in mediating cognitive control, working memory, and decision-making in both health and disease

Keywords

  • Brain networks
  • Friedreich Ataxia
  • cognitive control
  • cognitive neuroscience
  • functional neuroimaging techniques

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2016 2021

Research Output 2006 2019

Brain substrates of unhealthy versus healthy food choices: Influence of homeostatic status and body mass index

Harding, IH., Andrews, ZB., Mata, F., Orlandea, S., Martínez-Zalacaín, I., Soriano-Mas, C., Stice, E. & Verdejo-Garcia, A., 1 Mar 2018, In : International Journal of Obesity. 42, 3, p. 448-454 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Cerebral abnormalities in Friedreich Ataxia: A review

Selvadurai, L. P., Harding, I. H., Corben, L. A. & Georgiou-Karistianis, N., Jan 2018, In : Neuroscience and Biobehavioral Reviews. 84, p. 394-406 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Cerebral compensation during motor function in Friedreich ataxia: The IMAGE-FRDA study

Harding, I. H., Corben, L. A., Delatycki, M. B., Stagnitti, M. R., Storey, E., Egan, G. F. & Georgiou-Karistianis, N., Aug 2017, In : Movement Disorders. 32, 8, p. 1221-1229 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Cerebral and cerebellar grey matter atrophy in Friedreich ataxia: the IMAGE-FRDA study

Selvadurai, L. P., Harding, I. H., Corben, L. A., Stagnitti, M. R., Storey, E., Egan, G. F., Delatycki, M. B. & Georgiou-Karistianis, N., 1 Nov 2016, In : Journal of Neurology. 263, 11, p. 2215-2223 9 p.

Research output: Contribution to journalArticleResearchpeer-review