Projects per year
Personal profile
Biography
Dr Tran is currently appointed to the level of Adjunct Clinical Professor. He is Head of Haemostasis Thrombosis Unit and Director of the Haemophilia Treatment Centre (a state-wide service) at Alfred Health. The Alfred is a dynamic academic research organisation that is involved with basic science research and works to translate and integrate best evidence into routine standard of care, often in collaboration with The Australian Centre for Blood Diseases (ACBD) Monash University. Alfred Health is one of the premier organisations that thrives on delivering best care to complex patients.
Dr Tran is an active member of several research organisations, including the Haematology Clinical Research Unit (CRU), ACBD, Monash University, Thrombosis and Haemostasis Society of Australia and New Zealand (THANZ), and Australian Haemophilia Centres Directors’ Organisation (AHCDO). He has particular interests in the management of congenital haemophilia, venous thromboembolism (VTE) and its complications, rare bleeding disorders, immune platelet disorders and novel therapeutics. He has been the principal investigator for over 80 clinical trials in VTE diagnosis and management, haemophilia, and immune thrombocytopenia. He continues to supervise PhD (5), Master Phil (1), and numerous advanced haematology trainees.
He has a strong interest in standardising best practice and has led several published guidelines supported by specialty organisations in Australia, New Zealand and Asia Pacific regions. He is a strong supporter of medical education, training advanced haematology trainees (>30) and was a committee member of the Written Examination committee, Royal Australian College of Physicians (2008-15). He believes in the need to improve care in establishing countries and has lectured widely in the Asia-Pacific region, as well as, working with world federations societies for specific diseases. He is extremely active in AHCDO and THANZ, where he is the current Chair and Chair of the Clinical Trials Group (CTG) respectively. He works with governmental departments advisory boards and disease-specific advocacy groups to advocate for novel therapies to improve patient outcomes. He has a proven track record for leadership not only within Alfred Health but the wider community of haematology.
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Clinical activities
Clinical focus & Service Provision
Diagnostic testing and treatment for patients with hereditary bleeding disorders began in 1954, and was incorporated into duties and service delivery from the laboratory haematology department. Services were redeveloped following the retirement of Dr Sawers and recognition of HIV infection in plasma recipients in 1984. It was subsequently recognised by the Department of Health as adult state centre for management of patients with hereditary bleeding disorders offering a multidisciplinary model of care that encompasses the diagnosis, treatment and long-term follow up. Currently, we are the only international haemophilia training centre in Australia.
The RSHC won the Twinning Centre of the year in 2013 by the World Federation of Haemophilia for educational work with the National Institute of Haematology and Blood Transfusion, Hanoi, Vietnam. Today approximately 1100 patients are registered with the centre and the number continues to rise. Prof Tran has led over 40 clinical trials since 2007.
Our comprehensive service includes Haemophilia and other hereditary bleeding disorders allowing the effective delivery of both inpatient and outpatient care.
We provide a consultative service to other specialties within The Alfred hospital. Patients are also referred to us for treatment from numerous centres within Melbourne and regional Victoria
Education/Academic qualification
Haematology, FRACP, Royal Australasian College of Physicians (RACP)
Award Date: 1 Jan 2003
Haematology, FRCPA, Royal College of Pathologists of Australasia (RCPA)
Award Date: 1 Jan 2003
External positions
Chair, Australian Haemophilia Clinical Directors Organisation (AHCDO)
1 Nov 2017 → …
Chair, Clinical Trials Group, Thrombosis and Haemostasis Society of Australia and New Zealand (THANZ)
1 Apr 2015 → …
Director, Haemophilia Treatment Centre, Alfred Health
1 Feb 2012 → …
President, Thrombosis and Haemostasis Society of Australia and New Zealand (THANZ)
1 Nov 2011 → 1 Oct 2013
Medical Director, Laboratory Haematology, Monash Health
1 Feb 2010 → 1 Jan 2012
Head, Haemostasis Thrombosis Services, Alfred Hospital
1 Dec 2009 → …
Thrombosis Research Fellow, McMaster University
16 Oct 2003 → 1 Dec 2005
Research area keywords
- Thrombosis
- Haematology
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
Collaborations and top research areas from the last five years
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A TWO-PART OPEN-LABEL STUDY OF REGV131-LNP1265, A CRISPR/CAS9-BASED COAGULATION FACTOR IX GENE INSERTION THERAPY IN PARTICIPANTS WITH HEMOPHILIA B
Tran, H. (Primary Chief Investigator (PCI))
15/06/26 → 14/06/28
Project: Research
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SYNOVIIIUS: Prospective Interventional Study of Effectiveness of Efanesoctocog Alfa Prophylaxis on Synovial Hypertrophy in Patients with Hemophilia A
Tran, H. (Primary Chief Investigator (PCI))
16/01/26 → 31/10/30
Project: Research
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A Phase 3, Open-label, Multicenter Continuation Trial to Evaluate the Long-term Safety and Efficacy of Mezagitamab Subcutaneous Injection in Adults with Chronic Primary Immune Thrombocytopenia
Tran, H. (Primary Chief Investigator (PCI))
24/10/25 → 24/10/27
Project: Research
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A Phase 1/2 Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of HMB-002 in Participants with Von Willebrand Disease
Tran, H. (Primary Chief Investigator (PCI))
25/09/25 → 26/04/27
Project: Research
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A Prospective, Screening Study of Bleeding and Treatment in Participants with Von Willebrand Disease
Tran, H. (Primary Chief Investigator (PCI))
3/06/25 → 2/06/27
Project: Research
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Beyond platelet activation: dysregulated lipid metabolism in defining risk and pathophysiology of VITT
Stevens, H., McFadyen, J. D., Mellett, N. A., Lynn, D. J., Duong, T., Giles, C., James, J., Botten, R., Eden, G., Lynn, M., Monagle, P., Meikle, P. J., Chunilal, S., Peter, K. & Tran, H., Jan 2025, In: Research and Practice in Thrombosis and Haemostasis. 9, 1, 10 p., 102677.Research output: Contribution to journal › Article › Research › peer-review
Open Access3 Link opens in a new tab Citations (Scopus) -
Clinical utility of panel-based genetic sequencing for von Willebrand disease
Ramanan, R., Van Laer, C., Baert, S., Kint, C., Van Geet, C., Van Thillo, Q., Verhamme, P., Vanassche, T., McFadyen, J. D., Perkins, A. C., Tran, H. A., Labarque, V. & Freson, K., Feb 2025, In: Research and Practice in Thrombosis and Haemostasis. 9, 2, 13 p., 102730.Research output: Contribution to journal › Article › Research › peer-review
Open Access5 Link opens in a new tab Citations (Scopus) -
Efficacy and Long-Term Outcomes of Eltrombopag Treatment Within 6 Months of Diagnosis in Patients With Steroid Unresponsive or Dependent Immune Thrombocytopenia
Tran, H., Dix, C., Bird, R., Chunilal, S., Brighton, T., Reynolds, J., He, S., Mazis, C. & Grigg, A., Mar 2025, In: American Journal of Hematology. 100, 3, p. 516-519 4 p.Research output: Contribution to journal › Letter › Research › peer-review
Open Access1 Link opens in a new tab Citation (Scopus) -
Identification of Novel F9 Gene Variants in 143 Vietnamese Patients with Hemophilia B
Bach, K. Q., Duong, C. Q., Vu, H. T. B., Nguyen, B. T. N., Nguyen, T. T., Nguyen, M. T., Li, R., Hutchison, W., Esaq, F. S., Tran, H. & Nguyen, T. H., 2025, In: Journal of Blood Medicine. 16, p. 163-176 14 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Safety and efficacy of a fitusiran antithrombin-based dose regimen in people with hemophilia A or B: the ATLAS-OLE study
Young, G., Kavakli, K., Klamroth, R., Matsushita, T., Peyvandi, F., Pipe, S. W., Rangarajan, S., Shen, M. C., Srivastava, A., Sun, J., Tran, H., You, C. W., Zülfikar, B., Menapace, L. A., Zhang, C., Shen, Y., Puurunen, M., Demissie, M., Kenet, G. & for the ATLAS-OLE Trial Group, 19 Jun 2025, In: Blood. 145, 25, p. 2966-2977 12 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access37 Link opens in a new tab Citations (Scopus)
Prizes
Activities
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World Federation of Haemophilia Congress 2026
Tran, H. (Member of programme committee)
19 Apr 2026 → 22 Apr 2026Activity: Participating in or organising an event types › Contribution to conference
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Congress of the International-Society-on-Thrombosis-and-Haemostasis (ISTH) 2026
Tran, H. (Member of programme committee)
11 Jul 2026 → 15 Jul 2026Activity: Participating in or organising an event types › Contribution to conference
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Congress of the International-Society-on-Thrombosis-and-Haemostasis (ISTH) 2025
Tran, H. (Member of programme committee)
19 Jun 2025 → 25 Jun 2025Activity: Participating in or organising an event types › Contribution to conference
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Congress of the International-Society-on-Thrombosis-and-Haemostasis (ISTH)
Tran, H. (Member of programme committee)
2024Activity: Participating in or organising an event types › Contribution to conference
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COVID-19 national taskforce, Hospital and Acute care committee
Tran, H. (Member)
2023Activity: External Academic Engagement › Committees and working groups
Press/Media
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Thrombotic Thrombocytopenia Syndrome associated with AstraZeneca COVID-19 vaccine
7/07/21
1 Media contribution
Press/Media: Research