20082022

Research output per year

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Article
2019

Antibiotic resistance and host immune evasion in Staphylococcus aureus mediated by a metabolic adaptation

Jiang, J-H., Bhuiyan, M. S., Shen, H-H., Cameron, D. R., Rupasinghe, T. W. T., Wu, C. M., Le Brun, A. P., Kostoulias, X., Domene, C., Fulcher, A. J., McConville, M. J., Howden, B. P., Lieschke, G. J. & Peleg, A. Y., 26 Feb 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 9, p. 3722-3727 6 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Comparative metabolomics and transcriptomics reveal multiple pathways associated with polymyxin killing in pseudomonas aeruginosa

Han, M-L., Zhu, Y., Creek, D. J., Lin, Y-W., Gutu, A. D., Hertzog, P., Purcell, T., Shen, H-H., Moskowitz, S. M., Velkov, T. & Li, J., 1 Jan 2019, In : mSystems. 4, 1, 18 p., e00149-18.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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6 Citations (Scopus)
2018

Alterations of Metabolic and Lipid Profiles in Polymyxin-Resistant Pseudomonas aeruginosa

Han, M-L., Zhu, Y., Creek, D. J., Lin, Y-W., Anderson, D., Shen, H-H., Tsuji, B., Gutu, A. D., Moskowitz, S. M., Velkov, T. & Li, J., 1 Jun 2018, In : Antimicrobial Agents and Chemotherapy. 62, 6, 14 p., e02656-17.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

Annexin V-containing cubosomes for targeted early detection of apoptosis in degenerative retinal tissue

Ding, Y., Chow, S. H., Liu, G. S., Wang, B., Lin, T. W., Hsu, H. Y., Duff, A. P., Le Brun, A. P. & Shen, H. H., 2018, In : Journal of Materials Chemistry B. 6, 46, p. 7652-7661 10 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Polymyxin-Induced Lipid A Deacylation in Pseudomonas aeruginosa Perturbs Polymyxin Penetration and Confers High-Level Resistance

Han, M-L., Velkov, T., Zhu, Y., Roberts, K. D., Le Brun, A. P., Chow, S. H., Gutu, A. D., Moskowitz, S. M., Shen, H-H. & Li, J., 19 Jan 2018, In : ACS Chemical Biology. 13, 1, p. 121-130 10 p.

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)
2017

Investigating the Interaction of Octapeptin A3 with Model Bacterial Membranes

Han, M. L., Shen, H. H., Hansford, K. A., Schneider, E. K., Sivanesan, S., Roberts, K. D., Thompson, P. E., Le Brun, A. P., Zhu, Y., Sani, M-A., Separovic, F., Blaskovich, M. A. T., Baker, M. A., Moskowitz, S. M., Cooper, M. A., Li, J. & Velkov, T., 11 Aug 2017, In : ACS Infectious Diseases. 3, 8, p. 606-619 14 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

miR-378 reduces mesangial hypertrophy and kidney tubular fibrosis via MAPK signalling

Wang, B., Yao, K., Wise, A. F., Lau, R., Shen, H-H., Tesch, G. H. & Ricardo, S. D., 2017, In : Clinical Science. 131, 5, p. 411-423 13 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

Ultrathin 1T-phase MoS2 nanosheets decorated hollow carbon microspheres as highly efficient catalysts for solar energy harvesting and storage

Hsiao, M. C., Chang, C-Y., Niu, L-J., Bai, F., Li, L-J., Shen, H-H., Lin, J-Y. & Lin, T-W., 31 Mar 2017, In : Journal of Power Sources. 345, p. 156-164 9 p.

Research output: Contribution to journalArticleResearchpeer-review

26 Citations (Scopus)
2016

Effective assembly of fimbriae in Escherichia coli depends on the translocation assembly module nanomachine

Stubenrauch, C., Belousoff, M. J., Hay, I. D., Shen, H-H., Lillington, J., Tuck, K. L., Peters, K. M., Phan, M-D., Lo, A. W., Schembri, M. A., Strugnell, R. A., Waksman, G. & Lithgow, T., 2016, In : Nature Microbiology. 1, p. 1-8 8 p., 16064 .

Research output: Contribution to journalArticleResearchpeer-review

Open Access
24 Citations (Scopus)

Effect of lipid-based nanostructure on protein encapsulation within the membrane bilayer mimetic lipidic cubic phase using transmembrane and lipo proteins from the beta-barrel assembly machinery

van 't Hag, L., Shen, H-H., Lin, T-W., Gras, S. L., Drummond, C. J. & Conn, C. E., 29 Nov 2016, In : Langmuir. 32, 47, p. 12442-12452 11 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

Intraocular pressure induced retinal changes identified using synchrotron infrared microscopy

Shen, H-H., Liu, G. S., Chow, S. H., Wang, J-H., He, Z., Nguyen, C., Lin, T. W. & Bui, B. V., 6 Oct 2016, In : PLoS ONE. 11, 10, 14 p., e0164035.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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5 Citations (Scopus)

Mesenchymal stem cells deliver exogenous microRNA-let7c via exosomes to attenuate renal fibrosis

Wang, B., Yao, K., Huuskes, B. M., Shen, H-H., Zhuang, J., Godson, C., Brennan, E. P., Wilkinson-Berka, J. L., Wise, A. F. & Ricardo, S. D., 2016, In : Molecular Therapy. 24, 7, p. 1290-1301 12 p.

Research output: Contribution to journalArticleResearchpeer-review

95 Citations (Scopus)

Reversible coupling of 4-nitroaniline molecules to 4-aminothiophenol functionalized on Ag nanoparticle/graphene oxide nanocomposites through the plasmon assisted chemical reaction†

Tasi, T-T., Lin, T-W., Shao, L-D. & Shen, H-H., 1 Jan 2016, In : RSC Advances. 6, 35, p. 29453-29459 7 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)
2015

Conserved features in TamA enable interaction with TamB to drive the activity of the translocation and assembly module

Selkrig, J. P., Belousoff, M. J., Headey, S. J., Heinz, E., Shiota, T., Shen, H-H., Beckham, S. A., Bamert, R. S., Phan, M-D., Schembri, M. A., Wilce, M. C., Scanlon, M. J., Strugnell, R. A. & Lithgow, T. J., 2015, In : Scientific Reports. 5, 12 p., 12905.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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19 Citations (Scopus)

Deconvoluting the effect of the hydrophobic and hydrophilic domains of an amphiphilic integral membrane protein in lipid bicontinuous cubic mesophases

van 't Hag, L., Shen, H-H., Lu, J., Hawley, A. M., Gras, S. L., Drummond, C. J. & Conn, C. E., 2015, In : Langmuir. 31, 44, p. 12025 - 12034 10 p.

Research output: Contribution to journalArticleResearchpeer-review

17 Citations (Scopus)

Defining the structural characteristics of annexin V binding to a mimetic apoptotic membrane

Lu, J., Le Brun, A. P., Chow, S. H., Shiota, T., Wang, B., Lin, T-W., Liu, G-S. & Shen, H-H., 2015, In : European Biophysics Journal. 44, 8, p. 697 - 708 12 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Glucose-assisted synthesis of nickel-cobalt sulfide/carbon nanotube composites as efficient cathode materials for hybrid supercapacitors

Lin, T-W., Hsiao, M-C., Chou, S-W., Shen, H-H. & Lin, J-Y., 2015, In : Journal of the Electrochemical Society. 162, 8, p. 1493 - 1499 7 p.

Research output: Contribution to journalArticleResearchpeer-review

30 Citations (Scopus)

High-performance asymmetric supercapacitor based on Co9S8/3D graphene composite and graphene hydrogel

Lin, T-W., Dai, C-S., Tasi, T-T., Chou, S-W., Lin, J-Y. & Shen, H-H., 2015, In : Chemical Engineering Journal. 279, p. 241 - 249 9 p.

Research output: Contribution to journalArticleResearchpeer-review

56 Citations (Scopus)

Molecular architecture of the active mitochondrial protein gate

Shiota, T., Imai, K., Qiu, J., Hewitt, V. L., Tan, K. S., Shen, H-H., Sakiyama, N., Fukasawa, Y., Hayat, S., Kamiya, M., Elofsson, A., Tomii, K., Horton, P., Wiedemann, N., Pfanner, N., Lithgow, T. J. & Endo, T., 2015, In : Science. 349, 6255, p. 1544 - 1548 5 p.

Research output: Contribution to journalArticleResearchpeer-review

75 Citations (Scopus)

Nanocarriers for treatment of ocular neovascularization in the back of the eye: New vehicles for ophthalmic drug delivery

Shen, H-H., Chan, E. C., Lee, J. H., Bee, Y-S., Lin, T-W., Dusting, G. J. & Liu, G-S., 2015, In : Nanomedicine. 10, 13, p. 2093 - 2107 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
18 Citations (Scopus)

Self-assembly of bi-functional peptides on large-pore mesoporous silica nanoparticles for miRNA binding and delivery

Lu, J., Shen, H-H., Wu, Z. W., Wang, B., Zhao, D. & He, L., 2015, In : Journal of Materials Chemistry B. 39, 3, p. 7653 - 7657 5 p.

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)

Surface-enhanced Raman spectroscopy for DNA detection by the self-assembly of Ag nanoparticles onto Ag nanoparticle-graphene oxide nanocomposites

Lin, T-W., Wu, H-Y., Tasi, T-T., Lai, Y-H. & Shen, H-H., 2015, In : Physical Chemistry Chemical Physics. 17, 28, p. 18443 - 18448 6 p.

Research output: Contribution to journalArticleResearchpeer-review

36 Citations (Scopus)

Surfactin at the water/air interface and in solution

Iglesias-Fernandez, J., Darre, L., Kohlmeyer, A., Thomas, R. K., Shen, H-H. & Domene, C., 2015, In : Langmuir. 31, 40, p. 11097 - 11104 8 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)
2014

A mortise-tenon joint in the transmembrane domain modulates autotransporter assembly into bacterial outer membranes

Leyton, D. L., Johnson, M. D., Thapa, R., Huysmans, G., Dunstan, R. A., Celik, N., Shen, H-H., Loo, D., Belousoff, M. J., Purcell, A. W., Henderson, I. R., Beddoe, T. C., Rossjohn, J., Martin, L. L., Strugnell, R. A. & Lithgow, T. J., 2014, In : Nature Communications. 5, (Art. No.: 4239), p. 1 - 11 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
23 Citations (Scopus)

Reconstitution of a nanomachine driving the assembly of proteins into bacterial outer membranes

Shen, H-H., Leyton, D. L., Shiota, T., Belousoff, M. J., Noinaj, N., Lu, J., Holt, S. A., Tan, K. S., Selkrig, J. P., Webb, C. T., Buchanan, S. K., Martin, L. L. & Lithgow, T. J., 2014, In : Nature Communications. 5, 5078, p. 1 - 10 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
37 Citations (Scopus)

The pathogen Candida albicans hijacks pyroptosis for escape from macrophages

Uwamahoro, N., Verma-Gaur, J., Shen, H-H., Qu, Y., Lewis, R., Lu, J., Bambery, K. R., Masters, S. L., Vince, J., Naderer, T. & Traven, A., 2014, In : mBio. 5, 2, p. 1 - 11 11 p., e00003-14.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
80 Citations (Scopus)
2013

Application of the Gibbs equation to the adsorption of nonionic surfactants and polymers at the air-water interface: comparison with surface excesses determined directly using neutron reflectivity

Li, P. X., Li, Z. X., Shen, H-H., Thomas, R. K., Penfold, J. & Lu, J. R., 2013, In : Langmuir. 29, 30, p. 9324 - 9334 11 p.

Research output: Contribution to journalArticleResearchpeer-review

65 Citations (Scopus)

Targeted detection of phosphatidylserine in biomimetic membranes and in vitro cell systems using annexin V-containing cubosomes

Shen, H-H., Lake, V., Le Brun, A. P., James, M., Duff, A., Peng, Y., McLean, K. M. & Hartley, P. G., 2013, In : Biomaterials. 34, 33, p. 8361 - 8369 9 p.

Research output: Contribution to journalArticleResearchpeer-review

21 Citations (Scopus)
2012

Adsorption and self-assembly of biosurfactants studied by neutron reflectivity and small angle neutron scattering: glycolipids, lipopeptides and proteins

Penfold, J., Thomas, R. K. & Shen, H-H., 2012, In : Soft Matter. 8, p. 578 - 591 14 p.

Research output: Contribution to journalArticleResearchpeer-review

37 Citations (Scopus)

An x-ray and neutron reflectometry study of 'PEG-like' plasma polymer films

Menzies, D., Nelson, A., Shen, H-H., McLean, K., Forsythe, J., Gengenbach, T., Fong, C. & Muir, B., 2012, In : Journal of the Royal Society Interface. 9, 70, p. 1008 - 1019 12 p.

Research output: Contribution to journalArticleResearchpeer-review

17 Citations (Scopus)
2011

Comparison of positional surfactant isomers for displacement of rubisco protein from the air-water interface

He, L., Onaizi, S., Dimitrijev-Dwyer, M., Malcolm, A., Shen, H-H., Dong, C., Holt, S., Thomas, R. K. & Middelberg, A., 2011, In : Journal of Colloid and Interface Science. 360, 2, p. 617 - 622 6 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Surfactin strutures at interfaces and in solutoin: the effect of pH and cations

Shen, H-H., Lin, T-W., Thomas, R., Taylor, D. & Penfold, J., 2011, In : Journal of Physical Chemistry B. 115, 15, p. 4427 - 4435 9 p.

Research output: Contribution to journalArticleResearchpeer-review

22 Citations (Scopus)

The interaction of cubosomes with supported phospholipid bilayers using neutron reflectometry and QCM-D

Shen, H. H., Hartley, P. G., James, M., Nelson, A., Defendi, H. & McLean, K., 21 Sep 2011, In : Soft Matter. 7, 18, p. 8041-8049 9 p.

Research output: Contribution to journalArticleResearchpeer-review

22 Citations (Scopus)
2010

Destruction and solubilization of supported phospholipid bilayers on silica by the biosurfactant surfactin

Shen, H-H., Thomas, R., Penfold, J. & Fragnetto, G., 2010, In : Langmuir. 26, 10, p. 7334 - 7342 9 p.

Research output: Contribution to journalArticleResearchpeer-review

25 Citations (Scopus)

The influence of dipalmitoyl phosphatidylserine on phase behaviour of and cellular response to lyotropic liquid crystalline dispersions

Shen, H-H., Crowston, J., Huber, F., Saubern, S., McLean, K. & Hartley, P., 2010, In : Biomaterials. 31, 36, p. 9473 - 9481 9 p.

Research output: Contribution to journalArticleResearchpeer-review

56 Citations (Scopus)

The location of the biosurfactant surfactin in phospholipid bilayers supported on silica using neutron reflectometry

Shen, H-H., Thomas, R. & Taylor, P., 2010, In : Langmuir. 26, 1, p. 320 - 327 8 p.

Research output: Contribution to journalArticleResearchpeer-review

18 Citations (Scopus)

The synthesis of silica nanotubes through chlorosilanization of single wall carbon nanotubes

Lin, T-W. & Shen, H-H., 2010, In : Nanotechnology. 21, 36, p. 365604-1 - 365604-5 1 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)
2009

Aggregation of the naturally occurring lipopeptide, surfactin, at interfaces and in solution: an unusual type of surfactant?

Shen, H-H., Thomas, R., Chen, C-Y., Darton, R., Baker, S. & Penfold, J., 2009, In : Langmuir. 25, 7, p. 4211 - 4218 8 p.

Research output: Contribution to journalArticleResearchpeer-review

63 Citations (Scopus)

Cooperative tuneable interactions between a designed peptide biosurfactant and positional isomers of SDOBS at the air-water interface

He, L., Malcolm, A., Dimitrijev, M., Onaizi, S., Shen, H-H., Holt, S., Dexter, A., Thomas, R. & Middelberg, A., 2009, In : Langmuir. 25, 7, p. 4021 - 4026 6 p.

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)
2008

Structure of adsorbed layers of nitrophenoxy-tailed quaternary ammonium surfactants at the air/water interface studied by neutron reflection

Huang, X., Wang, Y., Dong, C., Shen, H-H. & Thomas, R., 2008, In : Journal of Colloid and Interface Science. 325, 1, p. 114 - 121 8 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

The interfacial structure and Young's modulus of peptide films having switchable mechanical properties

Middelberg, A., He, L., Dexter, A., Shen, H-H., Holt, S. & Thomas, R., 2008, In : Journal of the Royal Society Interface. 5, 18, p. 47 - 54 8 p.

Research output: Contribution to journalArticleResearchpeer-review

37 Citations (Scopus)