Personal profile

Biography

Dr. Horace (Wing Hei) Chan is a Research Fellow of the Stem Cells and Cancer Laboratory at Monash University, led by Professor Helen Abud. He obtained his PhD in Neuroscience and Developmental Biology from the University of Melbourne. Subsequently, he joined the Abud lab to specialise in the study of intestinal stem cells and colorectal cancer using organoid models. Dr. Chan's research focuses on utilising organoid models and CRISPR/Cas genome modification techniques, along with live cell imaging, to investigate the molecular mechanisms and environmental factors regulating stem cells in both normal tissues and tumours. He is particularly interested in understanding the role of regenerative stem cells in the intestines and their implications for colorectal cancer progression and drug resistance, utilising patient-derived colorectal cancer organoids as a key research tool. Dr. Chan's research contributes to advancing our understanding of stem cell biology and aims to improve the management and treatment of colorectal cancer.

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being
  • SDG 14 - Life Below Water

Research area keywords

  • neurodevelopment
  • Cancer Cell Biology

Collaborations and top research areas from the last five years

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