1997 …2027

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

Filter
Article
2020

Clinical and therapeutic predictors of disease outcomes in AQP4-IgG+ neuromyelitis optica spectrum disorder

Kunchok, A., Malpas, C., Nytrova, P., Havrdova, E. K., Alroughani, R., Terzi, M., Yamout, B., Hor, J. Y., Karabudak, R., Boz, C., Ozakbas, S., Olascoaga, J., Simo, M., Granella, F., Patti, F., McCombe, P., Csepany, T., Singhal, B., Bergamaschi, R., Fragoso, Y. & 21 others, Al-Harbi, T., Turkoglu, R., Lechner-Scott, J., Laureys, G., Oreja-Guevara, C., Pucci, E., Sola, P., Ferraro, D., Altintas, A., Soysal, A., Vucic, S., Grand'Maison, F., Izquierdo, G., Eichau, S., Lugaresi, A., Onofrj, M., Trojano, M., Marriott, M., Butzkueven, H., Kister, I. & Kalincik, T., 1 Feb 2020, In : Multiple Sclerosis and Related Disorders. 38, 8 p., 101868.

Research output: Contribution to journalArticleResearchpeer-review

Risk of secondary progressive multiple sclerosis: A longitudinal study

Fambiatos, A., Jokubaitis, V., Horakova, D., Kubala Havrdova, E., Trojano, M., Prat, A., Girard, M., Duquette, P., Lugaresi, A., Izquierdo, G., Grand’Maison, F., Grammond, P., Sola, P., Ferraro, D., Alroughani, R., Terzi, M., Hupperts, R., Boz, C., Lechner-Scott, J., Pucci, E. & 44 others, Bergamaschi, R., Van Pesch, V., Ozakbas, S., Granella, F., Turkoglu, R., Iuliano, G., Spitaleri, D., McCombe, P., Solaro, C., Slee, M., Ampapa, R., Soysal, A., Petersen, T., Sanchez-Menoyo, J. L., Verheul, F., Prevost, J., Sidhom, Y., Van Wijmeersch, B., Vucic, S., Cristiano, E., Saladino, M. L., Deri, N., Barnett, M., Olascoaga, J., Moore, F., Skibina, O., Gray, O., Fragoso, Y., Yamout, B., Shaw, C., Singhal, B., Shuey, N., Hodgkinson, S., Altintas, A., Al-Harbi, T., Csepany, T., Taylor, B., Hughes, J., Jun, J. K., van der Walt, A., Spelman, T., Butzkueven, H., Kalincik, T. & on behalf of the MSBase Study Group, Jan 2020, In : Multiple Sclerosis Journal. 26, 1, p. 79-90 12 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Vitamin D status in an Australian patient population: A large retrospective case series focusing on factors associated with variations in serum 25(OH)D

Voo, V. T. F., Stankovich, J., O'Brien, T. J., Butzkueven, H. & Monif, M., 4 Mar 2020, In : BMJ Open. 10, 3, 10 p., e032567.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2019

Anti-inflammatory disease-modifying treatment and disability progression in primary progressive multiple sclerosis: a cohort study

Lorscheider, J., Kuhle, J., Izquierdo, G., Lugaresi, A., Havrdova, E., Horakova, D., Hupperts, R., Duquette, P., Girard, M., Prat, A., Grand'Maison, F., Grammond, P., Sola, P., Ferraro, D., Trojano, M., Ramo-Tello, C., Lechner-Scott, J., Pucci, E., Solaro, C., Slee, M. & 7 others, Van Pesch, V., Sanchez Menoyo, J. L., van der Walt, A., Butzkueven, H., Kappos, L., Kalincik, T. & on behalf of the MSBase Study Group, 1 Feb 2019, In : European Journal of Neurology. 26, 2, p. 363-370 8 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Association of Initial Disease-Modifying Therapy with Later Conversion to Secondary Progressive Multiple Sclerosis

Brown, J. W. L., Coles, A., Horakova, D., Havrdova, E., Izquierdo, G., Prat, A., Girard, M., Duquette, P., Trojano, M., Lugaresi, A., Bergamaschi, R., Grammond, P., Alroughani, R., Hupperts, R., McCombe, P., Van Pesch, V., Sola, P., Ferraro, D., Grand'Maison, F., Terzi, M. & 20 others, Lechner-Scott, J., Flechter, S., Slee, M., Shaygannejad, V., Pucci, E., Granella, F., Jokubaitis, V., Willis, M., Rice, C., Scolding, N., Wilkins, A., Pearson, O. R., Ziemssen, T., Hutchinson, M., Harding, K., Jones, J., McGuigan, C., Butzkueven, H., Kalincik, T. & Robertson, N., 15 Jan 2019, In : JAMA. 321, 2, p. 175-187 13 p.

Research output: Contribution to journalArticleResearchpeer-review

34 Citations (Scopus)

Characterization of the human myelin oligodendrocyte glycoprotein antibody response in demyelination

Tea, F., Lopez, J. A., Ramanathan, S., Merheb, V., Lee, F. X. Z., Zou, A., Pilli, D., Patrick, E., van der Walt, A., Monif, M., Tantsis, E. M., Yiu, E. M., Vucic, S., Henderson, A. P. D., Fok, A., Fraser, C. L., Lechner-Scott, J., Reddel, S. W., Broadley, S., Barnett, M. H. & 5 others, Brown, D. A., Lunemann, J. D., Dale, R. C., Brilot, F. & Australasian and New Zealand MOG Study Group, 3 Sep 2019, In : Acta neuropathologica communications. 7, 1, 22 p., 145.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
9 Citations (Scopus)

Comparison of fingolimod, dimethyl fumarate and teriflunomide for multiple sclerosis

Kalincik, T., Kubala Havrdova, E., Horakova, D., Izquierdo, G., Prat, A., Girard, M., Duquette, P., Grammond, P., Onofrj, M., Lugaresi, A., Ozakbas, S., Kappos, L., Kuhle, J., Terzi, M., Lechner-Scott, J., Boz, C., Grand'Maison, F., Prevost, J., Sola, P., Ferraro, D. & 24 others, Granella, F., Trojano, M., Bergamaschi, R., Pucci, E., Turkoglu, R., McCombe, P. A., Pesch, V. V., Van Wijmeersch, B., Solaro, C., Ramo-Tello, C., Slee, M., Alroughani, R., Yamout, B., Shaygannejad, V., Spitaleri, D., Sánchez-Menoyo, J. L., Ampapa, R., Hodgkinson, S., Karabudak, R., Butler, E., Vucic, S., Jokubaitis, V., Spelman, T. & Butzkueven, H., 1 Apr 2019, In : Journal of Neurology, Neurosurgery and Psychiatry. 90, 4, p. 458-468 11 p.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)

Functional neuroplasticity in response to cerebello-thalamic injury underpins the clinical presentation of tremor in multiple sclerosis

Boonstra, F. M. C., Noffs, G., Perera, T., Jokubaitis, V. G., Vogel, A. P., Moffat, B. A., Butzkueven, H., Evans, A., van der Walt, A. & Kolbe, S. C., 25 Mar 2019, (Accepted/In press) In : Multiple Sclerosis Journal. 10 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Incidence of pregnancy and disease-modifying therapy exposure trends in women with multiple sclerosis: A contemporary cohort study

Nguyen, A. L., Havrdova, E. K., Horakova, D., Izquierdo, G., Kalincik, T., van der Walt, A., Terzi, M., Alroughani, R., Duquette, P., Girard, M., Prat, A., Boz, C., Sola, P., Ferraro, D., Lugaresi, A., Lechner-Scott, J., Barnett, M., Grand'Maison, F., Grammond, P., Ramo-Tello, C. & 26 others, Turkoglu, R., McCombe, P., Pucci, E., Trojano, M., Granella, F., Spitaleri, D., Van Pesch, V., Soysal, A., Oreja-Guevara, C., Verheul, F., Vucic, S., Hodgkinson, S., Slee, M., Ampapa, R., Prevost, J., Menoyo, J. L. S., Skibina, O., Solaro, C., Olascoaga, J., Shaw, C., Madsen, K. G., Naidoo, K., Hyde, R., Butzkueven, H., Jokubaitis, V. & on behalf of the MSBase Study Group, 1 Feb 2019, In : Multiple Sclerosis and Related Disorders. 28, p. 235-243 9 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

International consensus on quality standards for brain health-focused care in multiple sclerosis

Hobart, J., Bowen, A., Pepper, G., Crofts, H., Eberhard, L., Berger, T., Boyko, A., Boz, C., Butzkueven, H., Celius, E. G., Drulovic, J., Flores, J., Horáková, D., Lebrun-Frénay, C., Marrie, R. A., Overell, J., Piehl, F., Rasmussen, P. V., Sá, M. J., Sîrbu, C. A. & 7 others, Skromne, E., Torkildsen, Ø., van Pesch, V., Vollmer, T., Zakaria, M., Ziemssen, T. & Giovannoni, G., 1 Nov 2019, In : Multiple Sclerosis Journal. 25, 13, p. 1809-1818 10 p.

Research output: Contribution to journalArticleOtherpeer-review

Open Access
File
1 Citation (Scopus)

Multiple sclerosis registries in Europe – An updated mapping survey

Glaser, A., Stahmann, A., Meissner, T., Flachenecker, P., Horáková, D., Zaratin, P., Brichetto, G., Pugliatti, M., Rienhoff, O., Vukusic, S., de Giacomoni, A. C., Battaglia, M. A., Brola, W., Butzkueven, H., Casey, R., Drulovic, J., Eichstädt, K., Hellwig, K., Iaffaldano, P., Ioannidou, E. & 18 others, Kuhle, J., Lycke, K., Magyari, M., Malbaša, T., Middleton, R., Myhr, K. M., Notas, K., Orologas, A., Otero-Romero, S., Pekmezovic, T., Sastre-Garriga, J., Seeldrayers, P., Soilu-Hänninen, M., Stawiarz, L., Trojano, M., Ziemssen, T., Hillert, J. & Thalheim, C., 1 Jan 2019, In : Multiple Sclerosis and Related Disorders. 27, p. 171-178 8 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Redefining the Multiple Sclerosis Severity Score (MSSS): The effect of sex and onset phenotype

Zhou, Y., Claflin, S. B., Stankovich, J., van der Mei, I., Simpson, S., Roxburgh, R. H., Kalincik, T., Blizzard, L., Lugaresi, A., Alroughani, R., Sajedi, S. A., Butzkueven, H., Pucci, E., Spitaleri, D. L. A., Granella, F., Cristiano, E., Yamout, B., Hughes, S., Gouider, R., Sánchez Menoyo, J. L. & 18 others, Olascoaga, J., McGuigan, C., Shaw, C., Kermode, A. G., Kasa, K., Al-Harbi, T., Altintas, A., Laureys, G., Fragoso, Y., Hardy, T. A., Csepany, T., Sirbu, C. A., Decoo, D., Sas, A., Alvarez-Cermeño, J. C., Kotkata, K., Millán-Pascual, J. & Taylor, B. V., 31 Oct 2019, (Accepted/In press) In : Multiple Sclerosis Journal. 10 p.

Research output: Contribution to journalArticleResearchpeer-review

The feasibility, reliability and concurrent validity of the MSReactor computerized cognitive screening tool in multiple sclerosis

Merlo, D., Darby, D., Kalincik, T., Butzkueven, H. & van der Walt, A., Jul 2019, In : Therapeutic Advances in Neurological Disorders. 12, 15 p., UNSP 1756286419859183.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Uveitis in Patients with Multiple Sclerosis in Clinical Trials of Fingolimod: Incidence, Prevalence, and Impact on Disease Course

Lim, L. L., Silva, D. G., Lo, T. C., Pimentel, R. S., Butzkueven, H. & Hall, A. J., 1 Mar 2019, In : Ophthalmology. 126, 3, p. 438-444 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Validation of a precision tremor measurement system for multiple sclerosis

Perera, T., Lee, W. L., Yohanandan, S. A. C., Nguyen, A. L., Cruse, B., Boonstra, F. M. C., Noffs, G., Vogel, A. P., Kolbe, S. C., Butzkueven, H., Evans, A. & van der Walt, A., 1 Jan 2019, In : Journal of Neuroscience Methods. 311, p. 377-384 8 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Vitamin D increases glucocorticoid efficacy via inhibition of mTORC1 in experimental models of multiple sclerosis

Hoepner, R., Bagnoud, M., Pistor, M., Salmen, A., Briner, M., Synn, H., Schrewe, L., Guse, K., Ahmadi, F., Demir, S., Laverick, L., Gresle, M., Worley, P., Reichardt, H. M., Butzkueven, H., Gold, R., Metz, I., Lühder, F. & Chan, A., 1 Sep 2019, In : Acta Neuropathologica. 138, 3, p. 443–456 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
3 Citations (Scopus)
2018

Assessment of Opicinumab in Acute Optic Neuritis Using Multifocal Visual Evoked Potential

Klistorner, A., Chai, Y., Leocani, L., Albrecht, P., Aktas, O., Butzkueven, H., Ziemssen, T., Ziemssen, F., Frederiksen, J., Xu, L., Cadavid, D. & on behalf of RENEW MF-VEP Investigators, 1 Dec 2018, In : CNS Drugs. 32, 12, p. 1159-1171 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
9 Citations (Scopus)

Association of Inflammation and Disability Accrual in Patients with Progressive-Onset Multiple Sclerosis

Hughes, J., Jokubaitis, V., Lugaresi, A., Hupperts, R., Izquierdo, G., Prat, A., Girard, M., Duquette, P., Grand'maison, F., Grammond, P., Sola, P., Ferraro, DI., Ramo-Tello, C., Trojano, M., Slee, M., Shaygannejad, V., Boz, C., Lechner-Scott, J., Van Pesch, V., Pucci, E. & 12 others, Solaro, C., Verheul, F., Terzi, M., Granella, F., Spitaleri, D., Alroughani, R., Jun, J. K., Fambiatos, A., Van Der Walt, A., Butzkueven, H., Kalincik, T. & for the MSBase Study Group, 1 Nov 2018, In : JAMA Neurology. 75, 11, p. 1407-1415 9 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Cladribine versus fingolimod, natalizumab and interferon β for multiple sclerosis

Kalincik, T., Jokubaitis, V., Spelman, T., Horakova, D., Havrdova, E., Trojano, M., Lechner-Scott, J., Lugaresi, A., Prat, A., Girard, M., Duquette, P., Grammond, P., Solaro, C., Grand’Maison, F., Hupperts, R., Prevost, J., Sola, P., Ferraro, D., Terzi, M., Butler, E. & 9 others, Slee, M., Kermode, A., Fabis-Pedrini, M., McCombe, P., Barnett, M., Shaw, C., Hodgkinson, S., Butzkueven, H. & on behalf of the MSBase Study Group, Oct 2018, In : Multiple Sclerosis. 24, 12, p. 1617-1626 10 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Different patterns of longitudinal brain and spinal cord changes and their associations with disability progression in NMO and MS

Liu, Y., Duan, Y., Huang, J., Ren, Z., Liu, Z., Dong, H., Weiler, F., Hahn, H. K., Shi, F-D., Butzkueven, H., Barkhof, F. & Li, K., Jan 2018, In : European Radiology. 28, 1, p. 96-103 8 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Dysequilibrium of the PTH-FGF23-vitamin D axis in relapsing remitting multiple sclerosis; A longitudinal study

Stein, M. S., Ward, G. J., Butzkueven, H., Kilpatrick, T. J. & Harrison, L. C., 30 May 2018, In : Molecular Medicine. 24, 1, 9 p., 27.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
1 Citation (Scopus)

Evaluation of pregnancy outcomes in patients with multiple sclerosis after fingolimod exposure

Geissbühler, Y., Vile, J., Koren, G., Guennec, M., Butzkueven, H., Tilson, H., MacDonald, T. M. & Hellwig, K., 1 Jan 2018, In : Therapeutic Advances in Neurological Disorders. 11, 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
4 Citations (Scopus)

Greater sensitivity to multiple sclerosis disability worsening and progression events using a roving versus a fixed reference value in a prospective cohort study

Kappos, L., Butzkueven, H., Wiendl, H., Spelman, T., Pellegrini, F., Chen, Y., Dong, Q., Koendgen, H., Belachew, S., Trojano, M. & On Behalf of the Tysabri® Observational Program (TOP) Investigators, 1 Jun 2018, In : Multiple Sclerosis Journal. 24, 7, p. 963-973 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
9 Citations (Scopus)

Long-term disability trajectories in primary progressive MS patients: A latent class growth analysis

Signori, A., Izquierdo, G., Lugaresi, A., Hupperts, R., Grand’Maison, F., Sola, P., Horakova, D., Havrdova, E., Prat, A., Girard, M., Duquette, P., Boz, C., Grammond, P., Terzi, M., Singhal, B., Alroughani, R., Petersen, T., Ramo, C., Oreja-Guevara, C., Spitaleri, D. & 22 others, Shaygannejad, V., Butzkueven, H., Kalincik, T., Jokubaitis, V., Slee, M., Fernandez Bolaños, R., Sanchez-Menoyo, J. L., Pucci, E., Granella, F., Lechner-Scott, J., Iuliano, G., Hughes, S., Bergamaschi, R., Taylor, B., Verheul, F., Edite Rio, M., Amato, M. P., Sajedi, S. A., Majdinasab, N., Van Pesch, V., Sormani, M. P. & Trojano, M., 1 Apr 2018, In : Multiple Sclerosis. 24, 5, p. 642-652 11 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

Lymphocyte count in peripheral blood is not associated with the level of clinical response to treatment with fingolimod

Fragoso, Y. D., Spelman, T., Boz, C., Alroughani, R., Lugaresi, A., Vucic, S., Butzkueven, H., Terzi, M., Havrdova, E., Horakova, D., Granella, F., Olascoaga, J., Sánchez-Menoyo, J. L., Pucci, E., Barnett, M., Brooks, J. B. B., Haartsen, J. & on behalf of the Lymphopenia and Efficacy of Fingolimod MSBase sub-study Investigators, 1 Jan 2018, In : Multiple Sclerosis and Related Disorders. 19, p. 105-108 4 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Monitoring cognitive change in multiple sclerosis using a computerized cognitive battery

De Meijer, L., Merlo, D., Skibina, O., Grobbee, E. J., Gale, J., Haartsen, J., Maruff, P., Darby, D., Butzkueven, H. & Van Der Walt, A., 1 Nov 2018, In : Multiple Sclerosis Journal - Experimental, Translational and Clinica. 4, 4, p. 1-9 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Multimodal characterization of gray matter alterations in neuromyelitis optica

Liu, Y., Jiang, X., Butzkueven, H., Duan, Y., Huang, J., Ren, Z., Dong, H., Shi, F. D., Barkhof, F., Li, K. & Wang, J., 1 Sep 2018, In : Multiple Sclerosis Journal. 24, 10, p. 1308-1316 9 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Natalizumab treatment shows low cumulative probabilities of confirmed disability worsening to EDSS milestones in the long-term setting

Trojano, M., Butzkueven, H., Kappos, L., Wiendl, H., Spelman, T., Pellegrini, F., Chen, Y., Dong, Q., Koendgen, H., Belachew, S. & On Behalf of the Tysabri® Observational Program (TOP) Investigators, 1 Aug 2018, In : Multiple Sclerosis and Related Disorders. 24, p. 11-19 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2 Citations (Scopus)

Novel functional MRI task for studying the neural correlates of upper limb tremor

Boonstra, F. M. C., Perera, T., Noffs, G., Marotta, C., Vogel, A. P., Evans, A. H., Butzkueven, H., Moffat, B. A., van der Walt, A. & Kolbe, S. C., 2 Jul 2018, In : Frontiers in Neurology. 9, JUL, 7 p., 513.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2 Citations (Scopus)

Predictors of relapse and disability progression in MS patients who discontinue disease-modifying therapy

Kister, I., Spelman, T., Patti, F., Duquette, P., Trojano, M., Izquierdo, G., Lugaresi, A., Grammond, P., Sola, P., Ferraro, D., Grand'Maison, F., Alroughani, R., Terzi, M., Boz, C., Hupperts, R., Lechner-Scott, J., Kappos, L., Pucci, E., Hodgkinson, S., Solaro, C. & 1 others, Butzkueven, H., 15 Aug 2018, In : Journal of the Neurological Sciences. 391, p. 72-76 5 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Prognosis in autoimmune encephalitis: Database

Broadley, J., Seneviratne, U., Beech, P., Buzzard, K., Butzkueven, H., O'Brien, T. & Monif, M., 1 Dec 2018, In : Data in Brief. 21, p. 2694-2703 10 p.

Research output: Contribution to journalArticleOtherpeer-review

Open Access
File

Silent lesions on MRI imaging – Shifting goal posts for treatment decisions in multiple sclerosis

Min, M., Spelman, T., Lugaresi, A., Boz, C., Spitaleri, D. L. A., Pucci, E., Grand’Maison, F., Granella, F., Izquierdo, G., Butzkueven, H., Sanchez-Menoyo, J. L., Barnett, M., Girard, M., Trojano, M., Grammond, P., Duquette, P., Sola, P., Alroughani, R., Hupperts, R., Vucic, S. & 4 others, Kalincik, T., Van pesch, V., Lechner-Scott, J. & on behalf of MSBase Investigators, 1 Oct 2018, In : Multiple Sclerosis Journal. 24, 12, p. 1569-1577 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Vitamin D for the treatment of multiple sclerosis: a meta-analysis

McLaughlin, L., Clarke, L., Khalilidehkordi, E., Butzkueven, H., Taylor, B. & Broadley, S. A., 1 Dec 2018, In : Journal of Neurology. 265, 12, p. 2893-2905 13 p.

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)
2017

Anti-inflammatory disease-modifying treatment and short-term disability progression in SPMS

Lorscheider, J., Jokubaitis, V. G., Spelman, T., Izquierdo, G., Lugaresi, A., Havrdova, E., Horakova, D., Trojano, M., Duquette, P., Girard, M., Prat, A., Grand'Maison, F., Grammond, P., Pucci, E., Boz, C., Sola, P., Ferraro, DI., Spitaleri, D., Lechner-Scott, J., Terzi, M. & 9 others, Van Pesch, V., Iuliano, G., Bergamaschi, R., Ramo-Tello, C., Granella, F., Oreja-Guevara, C., Butzkueven, H., Kalincik, T. & on behalf of the MSBase Study Group, 5 Sep 2017, In : Neurology. 89, 10, p. 1050-1059 10 p.

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)

Contribution of different relapse phenotypes to disability in multiple sclerosis

Stewart, T., Spelman, T., Havrdova, E., Horakova, D., Trojano, M., Izquierdo, G., Duquette, P. P., Girard, M., Prat, A., Lugaresi, A., Grand'Maison, F., Grammond, P., Sola, P., Shaygannejad, V., Hupperts, R., Alroughani, R. A., Oreja-Guevara, C., Pucci, E., Boz, C., Lechner-Scott, J. & 35 others, Bergamaschi, R., Van Pesch, V., Iuliano, G., Ramo, C., Taylor, B. V., Slee, M., Spitaleri, D. L., Granella, F., Verheul, F., McCombe, P. A., Hodgkinson, S. J., Amato, M. P., Vucic, S., Gray, O. M., Cristiano, E., Barnett, M., Sanchez-Menoyo, J. L., Van Munster, E., Saladino, M. L., Olascoaga, J., Prevost, J., Deri, N. H., Shaw, C., Singhal, B., Moore, F. G. A., Rozsa, C., Shuey, N., Skibina, O., Kister, I., Petkovska-Boskova, T., Ampapa, R., Kermode, A., Butzkueven, H., Jokubaitis, V. & Kalincik, T., 1 Feb 2017, In : Multiple Sclerosis. 23, 2, p. 266-276 11 p.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)

Data quality evaluation for observational multiple sclerosis registries

Kalincik, T., Kuhle, J., Pucci, E., Rojas, J. I., Tsolaki, M., Sirbu, C-A., Slee, M. & Butzkueven, H., 1 Apr 2017, In : Multiple Sclerosis. 23, 5, p. 647-655 9 p.

Research output: Contribution to journalArticleResearchpeer-review

21 Citations (Scopus)

Gait and balance deterioration over a 12-month period in multiple sclerosis patients with EDSS scores ≤ 3.0

Galea, M. P., Cofré Lizama, L. E., Butzkueven, H. & Kilpatrick, T. J., 2017, In : NeuroRehabilitation. 40, 2, p. 277-284 8 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Highly active immunomodulatory therapy ameliorates accumulation of disability in moderately advanced and advanced multiple sclerosis

Lizak, N., Lugaresi, A., Alroughani, R. A., Lechner-Scott, J., Slee, M., Havrdova, E., Horakova, D., Trojano, M., Izquierdo, G., Duquette, P. P., Girard, M., Prat, A., Grammond, P., Hupperts, R., Grand'Maison, F., Sola, P., Pucci, E., Bergamaschi, R., Oreja-Guevara, C., Van Pesch, V. & 18 others, Ramo, C., Spitaleri, D. L., Iuliano, G., Boz, C., Granella, F., Olascoaga, J., Verheul, F., Rozsa, C., Cristiano, E., Flechter, S., Hodgkinson, S. J., Amato, M. P., Deri, N. H., Jokubaitis, V. G., Spelman, T., Butzkueven, H., Kalincik, T. & MSBase Study Group, 1 Mar 2017, In : Journal of Neurology, Neurosurgery and Psychiatry. 88, 3, p. 196-203 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
21 Citations (Scopus)

Incidence and prevalence of NMOSD in Australia and New Zealand

Bukhari, W., Prain, K. M., Waters, P., Woodhall, M., O'Gorman, C. M., Clarke, L., Silvestrini, R. A., Bundell, C. S., Abernethy, D., Bhuta, S., Blum, S., Boggild, M., Boundy, K. L., Brew, B. J., Brown, M., Brownlee, W. J., Butzkueven, H., Carroll, W. M., Chen, C., Coulthard, A. C. & 44 others, Dale, R. C., Das, C., Dear, K., Fabis-Pedrini, M. J., Fulcher, D. A., Gillis, D., Hawke, S., Heard, R., Henderson, A. P. D., Heshmat, S., Hodgkinson, S. J., Jimenez-Sanchez, S., Killpatrick, T., King, J., Kneebone, C., Kornberg, A. J., Lechner-Scott, J., Lin, M-W., Lynch, C., Macdonell, R., Mason, D. F., McCombe, P. A., Pender, M. P., Pereira, J. A., Pollard, J. D., Reddel, S. W., Shaw, C., Spies, J., Stankovich, J., Sutton, I. J., Vucic, S., Walsh, M., Wong, R. C., Yiu, E. M., Barnett, M. H., Kermode, A. G., Marriott, M. P., Parratt, J. D. E., Slee, M., Taylor, B. V., Willoughby, E., Wilson, R. J., Vincent, A. & Broadley, S. A., 1 Aug 2017, In : Journal of Neurology, Neurosurgery and Psychiatry. 88, 8, p. 632-638 7 p.

Research output: Contribution to journalArticleResearchpeer-review

25 Citations (Scopus)

Interleukin-2 receptor-α proximal promoter hypomethylation is associated with multiple sclerosis

Field, J., Fox, A., Jordan, M. A., Baxter, A. G., Spelman, T., Gresle, M. M., Butzkueven, H., Kilpatrick, T. J. & Rubio, J. P., 1 Mar 2017, In : Genes and Immunity. 18, 2, p. 59-66 8 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Prognostic indicators in pediatric clinically isolated syndrome

Iaffaldano, P., Simone, M., Lucisano, G., Ghezzi, A., Coniglio, G., Brescia Morra, V., Salemi, G., Patti, F., Lugaresi, A., Izquierdo, G., Bergamaschi, R., Cabrera-Gomez, J. A., Pozzilli, C., Millefiorini, E., Alroughani, R. A., Boz, C., Pucci, E., Zimatore, G. B., Sola, P., Lus, G. & 18 others, Maimone, D., Avolio, C., Cocco, E., Sajedi, S. A., Costantino, G., Duquette, P. P., Shaygannejad, V., Petersen, T., Fernández Bolaños, R., Paolicelli, D., Tortorella, C., Spelman, T., Margari, L., Amato, M. P., Comi, G., Butzkueven, H., Trojano, M. & on behalf of the Italian iMedWeb Registry and the MSBase Registry, 1 May 2017, In : Annals of Neurology. 81, 5, p. 729-739 11 p.

Research output: Contribution to journalArticleResearchpeer-review

20 Citations (Scopus)

Quantifying risk of early relapse in patients with first demyelinating events: Prediction in clinical practice

Spelman, T., Meyniel, C., Rojas, J. I., Lugaresi, A., Izquierdo, G., Grand’Maison, F., Boz, C., Alroughani, R. A., Havrdova, E., Horakova, D., Iuliano, G., Duquette, P. P., Terzi, M., Grammond, P., Hupperts, R., Lechner-Scott, J., Oreja-Guevara, C., Pucci, E., Verheul, F., Fiol, M. & 9 others, Van Pesch, V., Cristiano, E., Petersen, T., Moore, F. G. A., Kalincik, T., Jokubaitis, V. G., Trojano, M., Butzkueven, H. & on behalf of the MSBasis (an MSBase Substudy) Investigators, 1 Sep 2017, In : Multiple Sclerosis. 23, 10, p. 1346-1357 12 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

Safety and efficacy of opicinumab in acute optic neuritis (RENEW): a randomised, placebo-controlled, phase 2 trial

Cadavid, D., Balcer, L., Galetta, S., Aktas, O., Ziemssen, T., Vanopdenbosch, L., Frederiksen, J., Skeen, M., Jaffe, G. J., Butzkueven, H., Ziemssen, F., Massacesi, L., Chai, Y., Xu, L. & Freeman, S., 1 Mar 2017, In : The Lancet Neurology. 16, 3, p. 189-199 11 p.

Research output: Contribution to journalArticleResearchpeer-review

102 Citations (Scopus)

Towards personalized therapy for multiple sclerosis: Prediction of individual treatment response

Kalincik, T., Manouchehrinia, A., Sobisek, L., Jokubaitis, V., Spelman, T., Horakova, D., Havrdova, E., Trojano, M., Izquierdo, G., Lugaresi, A., Girard, M., Prat, A., Duquette, P., Grammond, P., Sola, P., Hupperts, R., Grand'Maison, F., Pucci, E., Boz, C., Alroughani, R. & 28 others, Van Pesch, V., Lechner-Scott, J., Terzi, M., Bergamaschi, R., Iuliano, G., Granella, F., Spitaleri, D., Shaygannejad, V., Oreja-Guevara, C., Slee, M., Ampapa, R., Verheul, F., McCombe, P., Olascoaga, J., Amato, M. P., Vucic, S., Hodgkinson, S., Ramo-Tello, C., Flechter, S., Cristiano, E., Rozsa, C., Moore, F., Sanchez-Menoyo, J. L., Saladino, M. L., Barnett, M., Hillert, J., Butzkueven, H. & on behalf of the MSBase Study Group, 1 Sep 2017, In : Brain. 140, 9, p. 2426-2443 18 p.

Research output: Contribution to journalArticleResearchpeer-review

25 Citations (Scopus)

Treatment effectiveness of alemtuzumab compared with natalizumab, fingolimod, and interferon beta in relapsing-remitting multiple sclerosis: a cohort study

Kalincik, T., Brown, J. W. L., Robertson, N., Willis, M. D., Scolding, N., Rice, C. M., Wilkins, A., Pearson, O., Ziemssen, T., Hutchinson, M., McGuigan, C., Jokubaitis, V. G., Spelman, T., Horakova, D., Havrdova, E., Trojano, M., Izquierdo, G., Lugaresi, A., Prat, A., Girard, M. & 30 others, Duquette, P. P., Grammond, P., Alroughani, R. A., Pucci, E., Sola, P., Hupperts, R., Lechner-Scott, J., Terzi, M., Van Pesch, V., Rozsa, C., Grand'Maison, F., Boz, C., Granella, F., Slee, M., Spitaleri, D. L., Olascoaga, J., Bergamaschi, R., Verheul, F., Vucic, S., McCombe, P. A., Hodgkinson, S. J., Sanchez-Menoyo, J. L., Ampapa, R., Simo, M., Csepany, T., Ramo, C., Cristiano, E., Barnett, M., Butzkueven, H. & Coles, A., 1 Apr 2017, In : The Lancet Neurology. 16, 4, p. 271-281 11 p.

Research output: Contribution to journalArticleResearchpeer-review

71 Citations (Scopus)

Tremor in multiple sclerosis is associated with cerebello-thalamic pathology

Boonstra, F., Florescu, G., Evans, A., Steward, C., Mitchell, P., Desmond, P., Moffat, B., Butzkueven, H., Kolbe, S. & van der Walt, A., 1 Dec 2017, In : Journal of Neural Transmission. 124, 12, p. 1509-1514 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
4 Citations (Scopus)
2016

Common and Low Frequency Variants in MERTK Are Independently Associated with Multiple Sclerosis Susceptibility with Discordant Association Dependent upon HLA-DRB1*15: 01 Status

Binder, M. D., Fox, A. D., Merlo, D., Johnson, L. J., Giuffrida, L., Calvert, S. E., Akkermann, R., Ma, G. Z. M., Australia and New Zealand Multiple Sclerosis Genetics Consortium (ANZGene), Perera, A. A., Gresle, M. M., Laverick, L., Foo, G., Fabis-Pedrini, M. J., Spelman, T., Jordan, M. A., Baxter, A. G., Foote, S., Butzkueven, H., Kilpatrick, T. J. & 1 others, Field, J., 1 Mar 2016, In : PLoS Genetics. 12, 3, 25 p., e1005853.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
9 Citations (Scopus)

Comparative efficacy of first-line natalizumab vs IFN-β or glatiramer acetate in relapsing MS

Spelman, T., Kalincik, T., Jokubaitis, V. G., Zhang, A., Pellegrini, F., Wiendl, H. S., Belachew, S., Hyde, R., Verheul, F., Lugaresi, A., Havrdová, E., Horáková, D., Grammond, P., Duquette, P. P., Prat, A., Iuliano, G., Terzi, M., Izquierdo, G., Hupperts, R. M. M., Boz, C. & 12 others, Pucci, E., Giuliani, G., Sola, P., Spitaleri, D. L. A., Lechner-Scott, J., Bergamaschi, R., Grand'Maison, F., Granella, F., Kappos, L. D., Trojano, M., Butzkueven, H. & On behalf of the MSBase Investigators and the TOP investigators, 1 Apr 2016, In : Neurology: Clinical Practice. 6, 2, p. 102-115 14 p.

Research output: Contribution to journalArticleResearchpeer-review

16 Citations (Scopus)

Defining secondary progressive multiple sclerosis

Lorscheider, J., Buzzard, K., Jokubaitis, V. G., Spelman, T., Havrdova, E., Horakova, D., Trojano, M., Izquierdo, G., Girard, M., Duquette, P. P., Prat, A., Lugaresi, A., Grand'maison, F., Grammond, P., Hupperts, R., Alroughani, R. A., Sola, P., Boz, C., Pucci, E., Lechner-Scott, J. & 25 others, Bergamaschi, R., Oreja-Guevara, C., Iuliano, G., Van Pesch, V., Granella, F., Ramo-Tello, C., Spitaleri, D. L., Petersen, T., Slee, M., Verheul, F., Ampapa, R., Amato, M. P., McCombe, P. A., Vucic, S., Sánchez Menoyo, J. L., Cristiano, E., Barnett, M. H., Hodgkinson, S. J., Olascoaga, J., Saladino, M. L., Gray, O. M., Shaw, C., Moore, F. G. A., Butzkueven, H. & Kalincik, T., 1 Sep 2016, In : Brain. 139, 9, p. 2395-2405 11 p.

Research output: Contribution to journalArticleResearchpeer-review

66 Citations (Scopus)

Discontinuing disease-modifying therapy in MS after a prolonged relapse-free period: A propensity score-matched study

Kister, I., Spelman, T., Alroughani, R. A., Lechner-Scott, J., Duquette, P. P., Grand'Maison, F., Slee, M., Lugaresi, A., Barnett, M., Grammond, P., Iuliano, G., Hupperts, R., Pucci, E., Trojano, M., Butzkueven, H. & on behalf of the MSBase Study Group, 1 Oct 2016, In : Journal of Neurology, Neurosurgery and Psychiatry. 87, 10, p. 1133-1137 5 p.

Research output: Contribution to journalArticleResearchpeer-review

33 Citations (Scopus)