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Helmut Butzkueven

Professor

 https://orcid.org/0000-0003-3940-8727

Accepting PhD Students

1997 …2024
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Biography

Professor Helmut Butzkueven 

Department of Neuroscience research groups - Butzkueven Lab

Helmut Butzkueven is  Professor of Neurology and Chair of Multiple Sclerosis and Neuroimmunology research in the Department of Neuroscience, Central Clinical School.

Professor Butzkueven is Head of Multiple Sclerosis and Neuroimmunology at the Alfred Hospital and Director of the MS service at Box Hill Hospital, Melbourne, Australia. He is Managing Director of the MSBase Foundation (www.msbase.org) that funds and administers a global online MS cohort study with more than 70000 patients enrolled in 130 centres across 27 countries.

His overarching research theme and clinical interest is the use of registry data, clinical MRI data, cognitive testing, genomics and patient self-monitoring devices and applications to evaluate treatment strategies to optimize benefit and safety of MS therapies. 

Research area keywords

  • Multiple Sclerosis (MS)
  • Clinical Outcomes
  • Participatory research
  • Pharmacogenomics
  • vitamin D
  • e-health

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Projects 2005 2024

Pharmacogenomic prediction of treatment response in multiple sclerosis

Van Der Walt, A., Jokubaitis, V. & Butzkueven, H.

21/10/19 → 20/04/20

Project: Research

Analysis of Real-World Long-Term Effectiveness of Ocrelizumab in Primary Progressive MS Disease

Butzkueven, H. & Hinson, E.

11/09/19 → 30/11/23

Project: Research

CLADIN sub study. Effect of CLADribine on Innate Immune Response (CLADIN). MS Immunity Project.

Monif, M., Butzkueven, H. & O'Brien, T.

27/06/19 → 9/09/22

Project: Research

Improved monitoring of Multiple Sclerosis (MS) using patient-derived and MRI scan information.

Butzkueven, H.

6/06/19 → 27/02/23

Project: Research

A global prospective open access study to assess and optimize the monitoring of Multiple Sclerosis using smartphones (floodlight open study)

Butzkueven, H. & Gresle, M.

31/03/19 → 31/03/24

Project: Research

Research Output 1997 2019

1 Citation (Scopus)

Anti-inflammatory disease-modifying treatment and disability progression in primary progressive multiple sclerosis: a cohort study

Lorscheider, J., Kuhle, J., Izquierdo, G., Lugaresi, A., Havrdova, E., Horakova, D., Hupperts, R., Duquette, P., Girard, M., Prat, A., Grand'Maison, F., Grammond, P., Sola, P., Ferraro, D., Trojano, M., Ramo-Tello, C., Lechner-Scott, J., Pucci, E., Solaro, C., Slee, M. & 7 others, Van Pesch, V., Sanchez Menoyo, J. L., van der Walt, A., Butzkueven, H., Kappos, L., Kalincik, T. & on behalf of the MSBase Study Group, 1 Feb 2019, In : European Journal of Neurology. 26, 2, p. 363-370 8 p.

Research output: Contribution to journal › Article › Research › peer-review

24 Citations (Scopus)

Association of Initial Disease-Modifying Therapy with Later Conversion to Secondary Progressive Multiple Sclerosis

Brown, J. W. L., Coles, A., Horakova, D., Havrdova, E., Izquierdo, G., Prat, A., Girard, M., Duquette, P., Trojano, M., Lugaresi, A., Bergamaschi, R., Grammond, P., Alroughani, R., Hupperts, R., McCombe, P., Van Pesch, V., Sola, P., Ferraro, D., Grand'Maison, F., Terzi, M. & 20 others, Lechner-Scott, J., Flechter, S., Slee, M., Shaygannejad, V., Pucci, E., Granella, F., Jokubaitis, V., Willis, M., Rice, C., Scolding, N., Wilkins, A., Pearson, O. R., Ziemssen, T., Hutchinson, M., Harding, K., Jones, J., McGuigan, C., Butzkueven, H., Kalincik, T. & Robertson, N., 15 Jan 2019, In : JAMA. 321, 2, p. 175-187 13 p.

Research output: Contribution to journal › Article › Research › peer-review

9 Citations (Scopus)

Comparison of fingolimod, dimethyl fumarate and teriflunomide for multiple sclerosis

Kalincik, T., Kubala Havrdova, E., Horakova, D., Izquierdo, G., Prat, A., Girard, M., Duquette, P., Grammond, P., Onofrj, M., Lugaresi, A., Ozakbas, S., Kappos, L., Kuhle, J., Terzi, M., Lechner-Scott, J., Boz, C., Grand'Maison, F., Prevost, J., Sola, P., Ferraro, D. & 24 others, Granella, F., Trojano, M., Bergamaschi, R., Pucci, E., Turkoglu, R., McCombe, P. A., Pesch, V. V., Van Wijmeersch, B., Solaro, C., Ramo-Tello, C., Slee, M., Alroughani, R., Yamout, B., Shaygannejad, V., Spitaleri, D., Sánchez-Menoyo, J. L., Ampapa, R., Hodgkinson, S., Karabudak, R., Butler, E., Vucic, S., Jokubaitis, V., Spelman, T. & Butzkueven, H., 1 Apr 2019, In : Journal of Neurology, Neurosurgery and Psychiatry. 90, 4, p. 458-468 11 p.

Research output: Contribution to journal › Article › Research › peer-review

1 Citation (Scopus)

Functional neuroplasticity in response to cerebello-thalamic injury underpins the clinical presentation of tremor in multiple sclerosis

Boonstra, F. M. C., Noffs, G., Perera, T., Jokubaitis, V. G., Vogel, A. P., Moffat, B. A., Butzkueven, H., Evans, A., van der Walt, A. & Kolbe, S. C., 25 Mar 2019, (Accepted/In press) In : Multiple Sclerosis Journal. 10 p.

Research output: Contribution to journal › Article › Research › peer-review

2 Citations (Scopus)

Incidence of pregnancy and disease-modifying therapy exposure trends in women with multiple sclerosis: A contemporary cohort study

Nguyen, A. L., Havrdova, E. K., Horakova, D., Izquierdo, G., Kalincik, T., van der Walt, A., Terzi, M., Alroughani, R., Duquette, P., Girard, M., Prat, A., Boz, C., Sola, P., Ferraro, D., Lugaresi, A., Lechner-Scott, J., Barnett, M., Grand'Maison, F., Grammond, P., Ramo-Tello, C. & 26 others, Turkoglu, R., McCombe, P., Pucci, E., Trojano, M., Granella, F., Spitaleri, D., Van Pesch, V., Soysal, A., Oreja-Guevara, C., Verheul, F., Vucic, S., Hodgkinson, S., Slee, M., Ampapa, R., Prevost, J., Menoyo, J. L. S., Skibina, O., Solaro, C., Olascoaga, J., Shaw, C., Madsen, K. G., Naidoo, K., Hyde, R., Butzkueven, H., Jokubaitis, V. & on behalf of the MSBase Study Group, 1 Feb 2019, In : Multiple Sclerosis and Related Disorders. 28, p. 235-243 9 p.

Research output: Contribution to journal › Article › Research › peer-review