1997 …2027

Research output per year

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Personal profile


Professor Helmut Butzkueven 

Department of Neuroscience research groups - Butzkueven Lab

Helmut Butzkueven is  Professor of Neurology and Chair of Multiple Sclerosis and Neuroimmunology research in the Department of Neuroscience, Central Clinical School.

Professor Butzkueven is Head of Multiple Sclerosis and Neuroimmunology at the Alfred Hospital and Director of the MS service at Box Hill Hospital, Melbourne, Australia. He is Managing Director of the MSBase Foundation (www.msbase.org) that funds and administers a global online MS cohort study with more than 70000 patients enrolled in 130 centres across 27 countries.

His overarching research theme and clinical interest is the use of registry data, clinical MRI data, cognitive testing, genomics and patient self-monitoring devices and applications to evaluate treatment strategies to optimize benefit and safety of MS therapies. 

Research area keywords

  • Multiple Sclerosis (MS)
  • Clinical Outcomes
  • Participatory research
  • Pharmacogenomics
  • vitamin D
  • e-health

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Research Output

Clinical and therapeutic predictors of disease outcomes in AQP4-IgG+ neuromyelitis optica spectrum disorder

Kunchok, A., Malpas, C., Nytrova, P., Havrdova, E. K., Alroughani, R., Terzi, M., Yamout, B., Hor, J. Y., Karabudak, R., Boz, C., Ozakbas, S., Olascoaga, J., Simo, M., Granella, F., Patti, F., McCombe, P., Csepany, T., Singhal, B., Bergamaschi, R., Fragoso, Y. & 21 others, Al-Harbi, T., Turkoglu, R., Lechner-Scott, J., Laureys, G., Oreja-Guevara, C., Pucci, E., Sola, P., Ferraro, D., Altintas, A., Soysal, A., Vucic, S., Grand'Maison, F., Izquierdo, G., Eichau, S., Lugaresi, A., Onofrj, M., Trojano, M., Marriott, M., Butzkueven, H., Kister, I. & Kalincik, T., 1 Feb 2020, In : Multiple Sclerosis and Related Disorders. 38, 8 p., 101868.

Research output: Contribution to journalArticleResearchpeer-review

Risk of secondary progressive multiple sclerosis: A longitudinal study

Fambiatos, A., Jokubaitis, V., Horakova, D., Kubala Havrdova, E., Trojano, M., Prat, A., Girard, M., Duquette, P., Lugaresi, A., Izquierdo, G., Grand’Maison, F., Grammond, P., Sola, P., Ferraro, D., Alroughani, R., Terzi, M., Hupperts, R., Boz, C., Lechner-Scott, J., Pucci, E. & 44 others, Bergamaschi, R., Van Pesch, V., Ozakbas, S., Granella, F., Turkoglu, R., Iuliano, G., Spitaleri, D., McCombe, P., Solaro, C., Slee, M., Ampapa, R., Soysal, A., Petersen, T., Sanchez-Menoyo, J. L., Verheul, F., Prevost, J., Sidhom, Y., Van Wijmeersch, B., Vucic, S., Cristiano, E., Saladino, M. L., Deri, N., Barnett, M., Olascoaga, J., Moore, F., Skibina, O., Gray, O., Fragoso, Y., Yamout, B., Shaw, C., Singhal, B., Shuey, N., Hodgkinson, S., Altintas, A., Al-Harbi, T., Csepany, T., Taylor, B., Hughes, J., Jun, J. K., van der Walt, A., Spelman, T., Butzkueven, H., Kalincik, T. & on behalf of the MSBase Study Group, Jan 2020, In : Multiple Sclerosis Journal. 26, 1, p. 79-90 12 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Vitamin D status in an Australian patient population: A large retrospective case series focusing on factors associated with variations in serum 25(OH)D

Voo, V. T. F., Stankovich, J., O'Brien, T. J., Butzkueven, H. & Monif, M., 4 Mar 2020, In : BMJ Open. 10, 3, 10 p., e032567.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Anti-inflammatory disease-modifying treatment and disability progression in primary progressive multiple sclerosis: a cohort study

Lorscheider, J., Kuhle, J., Izquierdo, G., Lugaresi, A., Havrdova, E., Horakova, D., Hupperts, R., Duquette, P., Girard, M., Prat, A., Grand'Maison, F., Grammond, P., Sola, P., Ferraro, D., Trojano, M., Ramo-Tello, C., Lechner-Scott, J., Pucci, E., Solaro, C., Slee, M. & 7 others, Van Pesch, V., Sanchez Menoyo, J. L., van der Walt, A., Butzkueven, H., Kappos, L., Kalincik, T. & on behalf of the MSBase Study Group, 1 Feb 2019, In : European Journal of Neurology. 26, 2, p. 363-370 8 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Association of Initial Disease-Modifying Therapy with Later Conversion to Secondary Progressive Multiple Sclerosis

Brown, J. W. L., Coles, A., Horakova, D., Havrdova, E., Izquierdo, G., Prat, A., Girard, M., Duquette, P., Trojano, M., Lugaresi, A., Bergamaschi, R., Grammond, P., Alroughani, R., Hupperts, R., McCombe, P., Van Pesch, V., Sola, P., Ferraro, D., Grand'Maison, F., Terzi, M. & 20 others, Lechner-Scott, J., Flechter, S., Slee, M., Shaygannejad, V., Pucci, E., Granella, F., Jokubaitis, V., Willis, M., Rice, C., Scolding, N., Wilkins, A., Pearson, O. R., Ziemssen, T., Hutchinson, M., Harding, K., Jones, J., McGuigan, C., Butzkueven, H., Kalincik, T. & Robertson, N., 15 Jan 2019, In : JAMA. 321, 2, p. 175-187 13 p.

Research output: Contribution to journalArticleResearchpeer-review

30 Citations (Scopus)