Projects per year
Personal profile
Biography
Professor Helmut Butzkueven is The The Van Cleef Roet Chair of Neuroscience and Head of the Department of Neuroscience, Monash University, and Director of Neurology, Alfred Health. He is also Chair of the Multiple Sclerosis and Neuroimmunology research unit in the Department of Neuroscience, Central Clinical School. He is an international leader in translational research in the neurological disease, Multiple Sclerosis (MS). He is Managing Director of the MSBase Foundation (www.msbase.org) that funds and administers a global online MS cohort study with more than 70,000 patients enrolled in 130 centres across 36 countries, which has resulted in multiple publications that have directly impacted on patient care worldwide.
He completed his PhD at the Walter and Eliza Hall Institute in 2003, and subsequently a post-doctoral fellowship at The Howard Florey Institute. He has received multiple awards for his research and medical leadership, including The Bethlehem Griffith Research Foundation Award, The Australian Museum and University of NSW Eureka Prize and the Research Australia Health and Medical Research Data Innovation Award. Currently, he holds a highly competitive NHMRC Research Leader Investigator Grant, recognising him as a leading medical researcher in Australia.
Research interests
His overarching research theme and clinical interest is the use of registry data, clinical MRI data, cognitive testing, genomics and patient self-monitoring devices and applications to evaluate treatment strategies to optimise the benefit and safety of MS therapies.
Clinical activities
In addition to his research leadership credentials, Prof. Butzkueven has over 20 years’ experience as a clinical neurologist, and is Head of the Multiple Sclerosis and Neuro Immunology (MSNI) Clinic at the Alfred Hospital, Melbourne, Australia. He is also a passionate teacher and mentor of young clinicians and researchers, and is Research Higher Degree Coordinator for the Central Clinical School, Monash University.
Community service
Professor Butzkueven also is a member on the Board of Directors at MS Research Australia. He has a long working history with MS Research Australia, initially awarded a Fellowship in 2006 to investigate protecting nerve cells from MS injury. Most recently he has been an active member on a number of working groups and collaborative platforms as well as volunteering as MS Research Australia’s Scientific Conference Convenor.
Education/Academic qualification
Post-Doctoral Fellowship, Florey Institute of Neuroscience and Mental Health (FINMH) (Victoria)
Research Fellowship, Multiple Sclerosis Research Australia
PhD, Walter and Eliza Hall Institute of Medical Research (WEHI)
External positions
Department of Neurology, Alfred Hospital
3 Aug 2020 → …Board Member, Multiple Sclerosis Research Australia
2018 → …Research area keywords
- Multiple Sclerosis (MS)
- Clinical Outcomes
- Participatory research
- Pharmacogenomics
- vitamin D
- e-health
Network
Projects
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The contribution of monocytes and P2X7 Receptor in Multiple Sclerosis relapse.
Monif, M., Butzkueven, H., O'Brien, T. & Stankovich, J.
2/03/21 → 31/12/21
Project: Research
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Autoimmune Encephalitis - a rare and debilitating neurological illness affecting the Australian population. A study of the Australian Autoimmune Encephalitis Consortium.
Monif, M., Butzkueven, H., Reddel, S. W., Kalincik, T., Tarlinton, D., Seneviratne, U., Kulkarni, J., Buzzard, K. & Taylor, B. V. M.
1/06/20 → 31/05/24
Project: Research
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Active self-monitoring to prospectively detect treatment failure and define subclinical progression trajectories in multiple sclerosis: The ACTIVE-MS Program.
Van Der Walt, A., Butzkueven, H., Jokubaitis, V., Kolbe, S., Vogel, A. P., Stankovich, J., Butler, E., Macdonell, R. A. L. & Darby, D.
Trish Multiple Sclerosis Research Foundation
1/01/20 → 31/12/22
Project: Research
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Monash-Roche Meaningful Data at Scale Collaboration for MS
Van Der Walt, A. & Butzkueven, H.
6/12/19 → 31/12/27
Project: Research
Research output
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Real-world effectiveness of cladribine for Australian patients with multiple sclerosis: An MSBase registry substudy
Lizak, N., Hodgkinson, S., Butler, E., Lechner-Scott, J., Slee, M., McCombe, P. A., Shaw, C., Skibina, O., Vucic, S., Shuey, N., Barnett, M. H., Parratt, J., Butzkueven, H., Jack, D., Fabris, J. & Kalincik, T., Mar 2021, In : Multiple Sclerosis Journal. 27, 3, p. 465-474 10 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Speech metrics, general disability, brain imaging and quality of life in multiple sclerosis
Noffs, G., Boonstra, F. M. C., Perera, T., Butzkueven, H., Kolbe, S. C., Maldonado, F., Cofre Lizama, L. E., Galea, M. P., Stankovich, J., Evans, A., van der Walt, A. & Vogel, A. P., Jan 2021, In : European Journal of Neurology. 28, 1, p. 259-268 10 p.Research output: Contribution to journal › Article › Research › peer-review
1 Citation (Scopus) -
Acoustic Speech Analytics Are Predictive of Cerebellar Dysfunction in Multiple Sclerosis
Noffs, G., Boonstra, F. M. C., Perera, T., Kolbe, S. C., Stankovich, J., Butzkueven, H., Evans, A., Vogel, A. P. & van der Walt, A., Oct 2020, In : Cerebellum. 19, 5, p. 691-700 10 p.Research output: Contribution to journal › Article › Research › peer-review
1 Citation (Scopus) -
Association of Pregnancy with the Onset of Clinically Isolated Syndrome
Nguyen, A. L., Vodehnalova, K., Kalincik, T., Signori, A., Havrdova, E. K., Lechner-Scott, J., Skibina, O. G., Eastaugh, A., Taylor, L., Baker, J., McGuinn, N., Rath, L., Maltby, V., Sormani, M. P., Butzkueven, H., Van Der Walt, A., Horakova, D. & Jokubaitis, V. G., Sep 2020, (Accepted/In press) In : JAMA Neurology. 8 p.Research output: Contribution to journal › Article › Research › peer-review
4 Citations (Scopus) -
Clinical and therapeutic predictors of disease outcomes in AQP4-IgG+ neuromyelitis optica spectrum disorder
Kunchok, A., Malpas, C., Nytrova, P., Havrdova, E. K., Alroughani, R., Terzi, M., Yamout, B., Hor, J. Y., Karabudak, R., Boz, C., Ozakbas, S., Olascoaga, J., Simo, M., Granella, F., Patti, F., McCombe, P., Csepany, T., Singhal, B., Bergamaschi, R., Fragoso, Y. & 21 others, , 1 Feb 2020, In : Multiple Sclerosis and Related Disorders. 38, 8 p., 101868.Research output: Contribution to journal › Article › Research › peer-review
7 Citations (Scopus)
Activities
- 1 External HDR Supervision
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PhD Supervision - Dr Ai-Lan Nguyen
Tomas Kalincik (Supervisor), Vilija Jokubaitis (Supervisor), Anneke Van Der Walt (Supervisor) & Helmut Butzkueven (Supervisor)
2017Activity: External Academic Engagement › External HDR Supervision