Projects per year
Personal profile
Biography
Professor Helmut Butzkueven is The The Van Cleef Roet Chair of Neuroscience and Head of the Department of Neuroscience, Monash University, and Director of Neurology, Alfred Health. He is also Chair of the Multiple Sclerosis and Neuroimmunology research unit in the Department of Neuroscience, Central Clinical School. He is an international leader in translational research in the neurological disease, Multiple Sclerosis (MS). He is Managing Director of the MSBase Foundation (www.msbase.org) that funds and administers a global online MS cohort study with more than 70,000 patients enrolled in 130 centres across 36 countries, which has resulted in multiple publications that have directly impacted on patient care worldwide.
He completed his PhD at the Walter and Eliza Hall Institute in 2003, and subsequently a post-doctoral fellowship at The Howard Florey Institute. He has received multiple awards for his research and medical leadership, including The Bethlehem Griffith Research Foundation Award, The Australian Museum and University of NSW Eureka Prize and the Research Australia Health and Medical Research Data Innovation Award. Currently, he holds a highly competitive NHMRC Research Leader Investigator Grant, recognising him as a leading medical researcher in Australia.
Research interests
His overarching research theme and clinical interest is the use of registry data, clinical MRI data, cognitive testing, genomics and patient self-monitoring devices and applications to evaluate treatment strategies to optimise the benefit and safety of MS therapies.
Clinical activities
In addition to his research leadership credentials, Prof. Butzkueven has over 20 years’ experience as a clinical neurologist, and is Head of the Multiple Sclerosis and Neuro Immunology (MSNI) Clinic at the Alfred Hospital, Melbourne, Australia. He is also a passionate teacher and mentor of young clinicians and researchers, and is Research Higher Degree Coordinator for the Central Clinical School, Monash University.
Community service
Professor Butzkueven also is a member on the Board of Directors at MS Research Australia. He has a long working history with MS Research Australia, initially awarded a Fellowship in 2006 to investigate protecting nerve cells from MS injury. Most recently he has been an active member on a number of working groups and collaborative platforms as well as volunteering as MS Research Australia’s Scientific Conference Convenor.
Education/Academic qualification
Post-Doctoral Fellowship, Florey Institute of Neuroscience and Mental Health (FINMH) (Victoria)
Research Fellowship, Multiple Sclerosis Research Australia (trading as National Multiple Sclerosis Research Foundation Limited)
PhD, Walter and Eliza Hall Institute of Medical Research (WEHI)
External positions
Department of Neurology, Alfred Hospital
3 Aug 2020 → …
Board Member, Multiple Sclerosis Research Australia (trading as National Multiple Sclerosis Research Foundation Limited)
2018 → …
Research area keywords
- Multiple Sclerosis (MS)
- Clinical Outcomes
- Participatory research
- Pharmacogenomics
- vitamin D
- e-health
Network
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Determining the risk of cervical precancer and cancer in women with multiple sclerosis: a national data linkage study.
Van Der Walt, A., Jokubaitis, V., Butzkueven, H., Taylor, B. V. M., Lechner-Scott, J. & Brotherton, J. J. M. L.
1/01/22 → 31/12/24
Project: Research
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InforMS – an electronic patient-driven health care model with digital biomarker monitoring that improves the clinical care of people with MS
van der Mei, I., Butzkueven, H., Taylor, B. V. M., Palmer, A. J., Blizzard, L. & Nicol, D.
3/05/21 → 3/05/23
Project: Research
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Autoimmune Encephalitis - a rare and debilitating neurological illness affecting the Australian population. A study of the Australian Autoimmune Encephalitis Consortium.
Monif, M., Butzkueven, H., Reddel, S. W., Kalincik, T., Tarlinton, D., Seneviratne, U., Kulkarni, J., Buzzard, K. & Taylor, B. V. M.
1/06/20 → 31/05/25
Project: Research
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Comparative Effectiveness and Cost-Effectiveness of Natalizumab and Fingolimod in Patients with Inadequate Response to Disease-Modifying Therapies in Relapsing-Remitting Multiple Sclerosis in the United Kingdom
Spelman, T., Herring, W. L., Zhang, Y., Tempest, M., Pearson, I., Freudensprung, U., Acosta, C., Dort, T., Hyde, R., Havrdova, E., Horakova, D., Trojano, M., De Luca, G., Lugaresi, A., Izquierdo, G., Grammond, P., Duquette, P., Alroughani, R., Pucci, E., Granella, F. & 15 others, , Mar 2022, In: PharmacoEconomics. 40, 3, p. 323-339 7 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Prediction of multiple sclerosis outcomes when switching to ocrelizumab
Zhong, M., van der Walt, A., Stankovich, J., Kalincik, T., Buzzard, K., Skibina, O., Boz, C., Hodgkinson, S., Slee, M., Lechner-Scott, J., Macdonell, R., Prevost, J., Kuhle, J., Laureys, G., Van Hijfte, L., Alroughani, R., Kermode, A. G., Butler, E., Barnett, M., Eichau, S. & 12 others, , May 2022, In: Multiple Sclerosis Journal. 28, 6, p. 958-969 12 p.Research output: Contribution to journal › Article › Research › peer-review
1 Citation (Scopus) -
Quantifying the impact of upper limb tremor on the quality of life of people with multiple sclerosis: a comparison between the QUEST and MSIS-29 scales
Tang, C. C., Soh, S. E., Boonstra, F., Noffs, G., Kolbe, S. C., Butzkueven, H., Evans, A. & Van der Walt, A., Feb 2022, In: Multiple Sclerosis and Related Disorders. 58, 6 p., 103495.Research output: Contribution to journal › Article › Research › peer-review
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Risk of requiring a wheelchair in primary progressive multiple sclerosis: Data from the ORATORIO trial and the MSBase registry
Butzkueven, H., Spelman, T., Horakova, D., Hughes, S., Solaro, C., Izquierdo, G., Kubala Havrdová, E., Grand'Maison, F., Prat, A., Girard, M., Hupperts, R., Onofrj, M., Lugaresi, A., Taylor, B., the MSBase Study Group, Giovannoni, G., Kappos, L., Hauser, S. L., Montalban, X., Craveiro, L. & 8 others, , Apr 2022, In: European Journal of Neurology. 29, 4, p. 1082-1090 9 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access5 Citations (Scopus) -
Subjective versus objective performance in people with multiple sclerosis using the MSReactor computerised cognitive tests.
Merlo, D., Kalincik, T., Zhu, C., Gresle, M., Lechner-Scott, J., Kilpatrick, T., Barnett, M., Taylor, B., Buzzard, K., Darby, D., Butzkueven, H. & van der Walt, A., Feb 2022, In: Multiple Sclerosis and Related Disorders. 58, 6 p., 103393.Research output: Contribution to journal › Article › Research › peer-review
Activities
- 1 External HDR Supervision
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PhD Supervision - Dr Ai-Lan Nguyen
Tomas Kalincik (Supervisor), Vilija Jokubaitis (Supervisor), Anneke Van Der Walt (Supervisor) & Helmut Butzkueven (Supervisor)
2017 → 12 May 2021Activity: External Academic Engagement › External HDR Supervision