1975 …2021

Research output per year

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2019

Chronic low alcohol intake during pregnancy programs sex-specific cardiovascular deficits in rats

Walton, S. L., Tjongue, M., Tare, M., Kwok, E., Probyn, M., Parkington, H. C., Bertram, J. F., Moritz, K. M. & Denton, K. M., 22 Apr 2019, In : Biology of Sex Differences. 10, 1, 14 p., 21.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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4 Citations (Scopus)

Powering Amyloid Beta Degrading Enzymes: A Possible Therapy for Alzheimer’s Disease

Sikanyika, N. L., Parkington, H. C., Smith, A. I. & Kuruppu, S., 15 Jun 2019, In : Neurochemical Research. 44, 6, p. 1289-1296 8 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Sepsis-induced acute kidney injury: A disease of the microcirculation

Ma, S., Evans, R. G., Iguchi, N., Tare, M., Parkington, H. C., Bellomo, R., May, C. N. & Lankadeva, Y. R., Feb 2019, In : Microcirculation. 26, 2, 10 p., e12483.

Research output: Contribution to journalArticleResearchpeer-review

20 Citations (Scopus)

Sustained Decrease in Blood Pressure and Reduced Anatomical and Functional Reinnervation of Renal Nerves in Hypertensive Sheep 30 Months After Catheter-Based Renal Denervation

Singh, R. R., McArdle, Z. M., Iudica, M., Easton, L. K., Booth, L. C., May, C. N., Parkington, H. C., Lombardo, P., Head, G. A., Lambert, G., Moritz, K. M., Schlaich, M. P. & Denton, K. M., 1 Mar 2019, In : Hypertension. 73, 3, p. 718-727 10 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)
2018

Angiotensin receptor blockade in juvenile male rat offspring: Implications for long-term cardio-renal health

Walton, S. L., Mazzuca, M. Q., Tare, M., Parkington, H. C., Wlodek, M. E., Moritz, K. M. & Gallo, L. A., Aug 2018, In : Pharmacological Research. 134, p. 320-331 12 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Cognitive sex differences in effects of music in Wisconsin Card Sorting Test

Feizpour, A., Parkington, H. C. & Mansouri, F. A., 12 Sep 2018, (Accepted/In press) In : Psychology of Music. 14 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Neural Electrodes Based on 3D Organic Electroactive Microfibers

Marroquin, J. B., Coleman, H. A., Tonta, M. A., Zhou, K., Winther-Jensen, B., Fallon, J., Duffy, N. W., Yan, E., Abdulwahid, A. A., Jasieniak, J. J., Forsythe, J. S. & Parkington, H. C., 21 Mar 2018, In : Advanced Functional Materials. 28, 12, 12 p., 1700927.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Perilipin 5 deletion unmasks an endoplasmic reticulum Stress-Fibroblast growth factor 21 axis in skeletal muscle

Montgomery, M. K., Mokhtar, R., Bayliss, J., Parkington, H. C., Suturin, V. M., Bruce, C. R. & Watt, M. J., 1 Apr 2018, In : Diabetes. 67, 4, p. 594-606 13 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

The immunoproteasome inhibitor ONX-0914 regulates inflammation and expression of contraction associated proteins in myometrium

Liong, S., Lim, R., Nguyen-Ngo, C., Barker, G., Parkington, H. C. & Lappas, M., 1 Aug 2018, In : European Journal of Immunology. 48, 8, p. 1350-1363 14 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Uteroplacental insufficiency temporally exacerbates salt-induced hypertension associated with a reduced natriuretic response in male rat offspring

Gallo, L. A., Walton, S. L., Mazzuca, M. Q., Tare, M., Parkington, H. C., Wlodek, M. E. & Moritz, K. M., 1 Dec 2018, In : Journal of Physiology. 596, 23, p. 5859-5872 14 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Wireless multichannel optogenetic stimulators enabled by narrow bandwidth resonant tank circuits

Aldaoud, A., Soto-Breceda, A., Tong, W., Conductier, G., Tonta, M. A., Coleman, H. A., Parkington, H. C., Clarke, I., Redoute, J-M., Garrett, D. J. & Prawer, S., 1 Mar 2018, In : Sensors and Actuators, A: Physical. 271, p. 201-211 11 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

β3-tripeptides act as sticky ends to self-assemble into a bioscaffold

Del Borgo, M. P., Kulkarni, K., Tonta, M. A., Ratcliffe, J. L., Seoudi, R., Mechler, A. I., Perlmutter, P., Parkington, H. C. & Aguilar, M-I., 1 May 2018, In : APL Bioengineering. 2, 2, 9 p., 026104.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2017

Mother Nature versus Father Time

Parkington, H. C., Sheehan, P. M., Coleman, H. A. & Brennecke, S. P., 15 Mar 2017, In : The Journal of Physiology. 595, 6, p. 1849-1850 2 p.

Research output: Contribution to journalArticleResearchpeer-review

Vasoactive actions of nitroxyl (HNO) are preserved in resistance arteries in diabetes

Tare, M., Kalidindi, R. S. R., Bubb, K. J., Parkington, H. C., Boon, W-M., Li, X., Sobey, C. G., Drummond, G. R., Ritchie, R. H. & Kemp-Harper, B. K., Apr 2017, In : Naunyn-Schmiedeberg's Archives of Pharmacology. 390, 4, p. 397-408 12 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)
2016

A novel conditional mouse model for Nkx2-5 reveals transcriptional regulation of cardiac ion channels

Furtado, M. B., Wilmanns, J., Chandran, A., Tonta, M. A., Biben, C., Eichenlaub, M. P., Coleman, H. A., Berger, S., Bouveret, R., Singh, R., Harvey, R. P., Ramialison, M. S. M., Pearson, J. T., Parkington, H. C., Rosenthal, N. A. & Da Costa, M. W., 2016, In : Differentiation. 91, 1-3, p. 29 - 41 13 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

CORRIGENDUM: N-terminal domain of Bothrops asper Myotoxin II Enhances the Activity of Endothelin Converting Enzyme-1 and Neprilysin

Smith, A. I., Rajapakse, N. W., Kleifeld, O., Lomonte, B., Sikanyika, N. L., Spicer, A. J., Hodgson, W. C., Conroy, P., Small, D. H., Kaye, D. M., Parkington, H. C., Whisstock, J. & Kuruppu, D. M. S., 2016, In : Scientific Reports. 6, Article # 24333, p. 1 - 1 1 p.

Research output: Contribution to journalArticleOther

Graphene functionalized scaffolds reduce the inflammatory response and supports endogenous neuroblast migration when implanted in the Adult Brain

Zhou, K., Motamed, S., Thouas, G. A., Bernard, C. C., Li, D., Parkington, H. C., Coleman, H. A., Finkelstein, D. I. & Forsythe, J. S., 15 Mar 2016, In : PLoS ONE. 11, 3, 15 p., e0151589.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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41 Citations (Scopus)

Learning, memory and long-term potentiation are altered in Nedd4 heterozygous mice

Camera, D., Coleman, H. A., Parkington, H. C., Jenkins, T. A., Pow, D. V., Boase, N., Kumar, S. & Poronnik, P., 15 Apr 2016, In : Behavioural Brain Research. 303, p. 176-181 6 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Maternal creatine supplementation during pregnancy prevents long-term changes in diaphragm muscle structure and function after birth asphyxia

LaRosa, D. A., Ellery, S. J., Parkington, H. C., Snow, R. J., Walker, D. W. & Dickinson, H., 1 Mar 2016, In : PLoS ONE. 11, 3, 17 p., e0149840.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
9 Citations (Scopus)

N-terminal domain of Bothrops asper Myotoxin II Enhances the Activity of Endothelin Converting Enzyme-1 and Neprilysin

Smith, A. I., Rajapakse, N. W., Kleifeld, O., Lomonte, B., Sikanyika, N. L., Spicer, A. J., Hodgson, W. C., Conroy, P. J., Small, D. H., Kaye, D. M., Parkington, H. C., Whisstock, J. C. & Kuruppu, S. M. S., 2 Mar 2016, In : Scientific Reports. 6, 10 p., 22413.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
8 Citations (Scopus)

Sex dependency of inhibitory control functions

Mansouri, F. A., Fehring, D. J., Gaillard, A., Jaberzadeh, S. & Parkington, H., 2016, In : Biology of Sex Differences. 7, 13 p., 11.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
17 Citations (Scopus)

Stimulating the Activity of Amyloid-Beta Degrading Enzymes: A Novel Approach for the Therapeutic Manipulation of Amyloid-Beta Levels

Kuruppu, S., Rajapakse, N. W., Spicer, A. J., Parkington, H. C. & Smith, A. I., 4 Oct 2016, In : Journal of Alzheimer's Disease. 54, 3, p. 891-895 5 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)
2015

Accelerated age-related decline in renal and vascular function in female rats following early-life growth restriction

Black, M. J., Lim, K. J., Zimanyi, M. A., Sampson, A. K., Bubb, K. J., Flower, R. L., Parkington, H. C., Tare, M. & Denton, K. M., 2015, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 309, 9, p. 1153 - 1161 9 p.

Research output: Contribution to journalArticleResearchpeer-review

20 Citations (Scopus)

Renal dysfunction is associated with a reduced contribution of nitric oxide and enhanced vasoconstriction after a congenital renal mass reduction in sheep

Lankadeva, Y. R., Singh, R. R., Moritz, K. M., Parkington, H. C., Denton, K. M. & Tare, M., 2015, In : Circulation. 131, 3, p. 280 - 288 9 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)
2014

Acute intravenous injection of serelaxin (recombinant human relaxin-2) causes rapid and sustained bradykinin-mediated vasorelaxation

Leo, C. H., Jelinic, M., Parkington, H. C., Tare, M. & Parry, L. J., 2014, In : American Heart Association. Journal. Cardiovascular and Cerebrovascular Disease. 3, 1 (Art. No: e000493), p. 1 - 20 20 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
38 Citations (Scopus)

Diminished hERG K+ channel activity facilitates strong human labour contractions but is dysregulated in obese women

Parkington, H. C., Stevenson, J. L., Tonta, M. A., Paul, J. W., Butler, T., Maiti, K., Chan, E-C., Sheehan, P. M., Brennecke, S. P., Coleman, H. A. & Smith, R., 2014, In : Nature Communications. 5, (Art. No: 4108), p. 1 - 8 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
26 Citations (Scopus)

Evidence that diet-induced hyperleptinemia, but not hypothalamic gliosis, causes ghrelin resistance in NPY/AgRP neurons of male mice

Briggs, D. I., Lockie, S. K. H., Benzler, J., Wu, Q., Stark, R., Reichenbach, A., Hoy, A. J., Lemus, M. B., Coleman, H. A., Parkington, H. C., Tups, A. & Andrews, Z. B., 2014, In : Endocrinology. 155, 7, p. 2411 - 2422 12 p.

Research output: Contribution to journalArticleResearchpeer-review

36 Citations (Scopus)

Exposure to intrauterine inflammation leads to impaired function and altered structure in the preterm heart of fetal sheep

Tare, M., Bensley, J. G., Moss, T. J. M., Lingwood, B. E., Kim, M. Y., Barton, S. K., Kluckow, M., Gill, A. W., De Matteo, R. M., Harding, R., Black, M. J., Parkington, H. C. & Polglase, G. R., 2014, In : Clinical Science. 127, 9, p. 559 - 569 11 p.

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)

Gonadotropin inhibitory hormone (GnIH) as a regulator of gonadotropes

Clarke, I. J. & Parkington, H. C., 2014, In : Molecular and Cellular Endocrinology. 385, 1-2, p. 36 - 44 9 p.

Research output: Contribution to journalArticleResearchpeer-review

22 Citations (Scopus)

Hypotensive and vascular relaxant effects of phospholipase A2 toxins from Papuan taipan (Oxyuranus scutellatus) venom

Chaisakul, J., Isbister, G. K., Tare, M., Parkington, H. C. & Hodgson, W. C., 2014, In : European Journal of Pharmacology. 723, 1, p. 227 - 233 7 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

Localization of relaxin receptors in arteries and veins, and region-specific increases in compliance and bradykinin-mediated relaxation after in vivo serelaxin treatment

Jelinic, M., Leo, C. H., Post Uiterweer, E. D., Sandow, S. L., Gooi, J. H., Wlodek, M. E., Conrad, K. P., Parkington, H. C., Tare, M. & Parry, L. J., 2014, In : FASEB Journal. 28, 1, p. 275 - 287 13 p.

Research output: Contribution to journalArticleResearchpeer-review

67 Citations (Scopus)

Maternal alcohol consumption in pregnancy enhances arterial stiffness and alters vasodilator function that varies between vascular beds in fetal sheep

Parkington, H. C., Kenna, K. R., Sozo, F., Coleman, H. A., Bocking, A., Brien, J. F., Harding, R. L., Walker, D. W., Morley, R. & Tare, M., 2014, In : The Journal of Physiology. 592, 12, p. 2591 - 2603 13 p.

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)

Neuronal electrophysiological function and control of neurite outgrowth on electrospun polymer nanofibers are cell type dependent

Bourke, J. L., Coleman, H. A., Pham, V., Forsythe, J. S. & Parkington, H. C., 2014, In : Tissue Engineering - Part A. 20, 5-6, p. 1089 - 1095 7 p.

Research output: Contribution to journalArticleResearchpeer-review

18 Citations (Scopus)
2013

Derivation of endothelial cells from human embryonic stem cells in fully defined medium enables identification of lysophosphatidic acid and platelet activating factor as regulators of eNOS localization

Costa, M., Sourris, K., Lim, S. M., Yu, Q. C., Hirst, C. E., Parkington, H. C., Jameson-Jokubaitis, V. J., Dear, A. E., Liu, H. B., Micallef, S. J., Koutsis, K., Elefanty, A. G. & Stanley, E., 2013, In : Stem Cell Research. 10, 1, p. 103 - 117 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
21 Citations (Scopus)
4 Citations (Scopus)

Paradoxical effect of gonadotropin-inhibiting hormone (GnIH) to negatively regulate neuropeptide Y neurons in mouse arcuate nucleus

Jacobi Elizondo, J. S., Coleman, H. A., Enriori, P., Parkington, H. C., Li, Q., Pereira, A., Cowley, M. A. & Clarke, I. J., 2013, In : Journal of Neuroendocrinology. 25, 12, p. 1308 - 1317 10 p.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)

Pulmonary delivery of an ultra-fine oxytocin dry powder formulation: Potential for treatment of postpartum haemorrhage in developing countries

Prankerd, R. J., Nguyen, T-H., Ibrahim, J., Bischof, R., Nassta, G., Olerile, L. D., Russell, A. S., Meiser, F., Parkington, H. C., Coleman, H. A., Morton, D. A. V. & McIntosh, M. P., 2013, In : PLoS ONE. 8, 12, 9 p., e82965.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
12 Citations (Scopus)
2012

Adiponectin increases insulin content and cell proliferation in MIN6 cells via PPARgamma-dependent and PPARgamma-independent mechanisms

Rao, J. R., Keating, D. J., Chen, C. & Parkington, H. C., 2012, In : Diabetes, Obesity and Metabolism. 14, 11, p. 983 - 989 7 p.

Research output: Contribution to journalArticleResearchpeer-review

30 Citations (Scopus)

Alcohol exposure during late gestation: multiple developmental outcomes in sheep

Kenna, K. R., Sozo, F., De Matteo, R. M., Hanita, T., Gray, S. P., Tare, M., Moritz, K. M., Bertram, J. F., Black, M. J., Brien, J. F., Parkington, H. C., Walker, D. W. & Harding, R., 2012, In : Journal of Developmental Origins of Health and Disease. 3, 4, p. 224 - 236 13 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

Comparative study on the therapeutic potential of neurally differentiated stem cells in a mouse model of multiple sclerosis

Payne, N. L., Sun, G., Herszfeld, D., Tat-Goh, P. A., Verma, P. J., Parkington, H. C., Coleman, H. A., Tonta, M. A., Siatskas, C. & Bernard, C. C. A., 2012, In : PLoS ONE. 7, 4, 14 p., e35093.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
17 Citations (Scopus)

Effect of maternal administration of allopregnanolone before birth asphyxia on neonatal hippocampal function in the spiny mouse

Fleiss, B., Parkington, H. C., Coleman, H. A., Dickinson, H., Yawno, T., Zakhem, M., Hirst, J. J. & Walker, D. W., 2012, In : Brain Research. 1433, p. 9 - 19 11 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

In vivo and in vitro cardiovascular effects of Papuan taipan (Oxyuranus scutellatus) venom: Exploring "sudden collapse"

Chaisakul, J., Isbister, G. K., Konstantakopoulos, N., Tare, M., Parkington, H. C. & Hodgson, W. C., 2012, In : Toxicology Letters. 213, 2, p. 243 - 248 6 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

Long-term alteration in maternal blood pressure and renal function after pregnancy in normal and growth-restricted rats

Gallo, L. A., Denton, K. M., Moritz, K. M., Tare, M., Parkington, H. C., Davies, M. M., Tran, M., Jefferies, A. J. & Wlodek, M. E., 2012, In : Hypertension. 60, 1, p. 206 - 213 8 p.

Research output: Contribution to journalArticleResearchpeer-review

19 Citations (Scopus)

Neural differentiation of patient specific iPS cells as a novel approach to study the pathophysiology of multiple sclerosis

Song, B., Sun, G., Herszfeld, D., Sylvain, A., Campanale, N. V., Hirst, C. E., Caine, S., Parkington, H. C., Tonta, M. A., Coleman, H. A., Short, M. A., Ricardo, S. D., Reubinoff, B. & Bernard, C. C. A., 2012, In : Stem Cell Research. 8, 2, p. 259 - 273 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
60 Citations (Scopus)

Over-expression of RCAN1 causes Down syndrome-like hippocampal deficits that alter learning and memory

Martin, K., Corlett, A., Dubach, D., Mustafa, T., Coleman, H. A., Parkington, H. C., Merson, T. D., Bourne, J. A., Porta, S., Arbones, M. L., Finkelstein, D. I. & Pritchard, M. A., 2012, In : Human Molecular Genetics. 21, 13, p. 3025 - 3041 17 p.

Research output: Contribution to journalArticleResearchpeer-review

52 Citations (Scopus)

Potassium and ANO1/ TMEM16A chloride channel profiles distinguish atypical and typical smooth muscle cells from interstitial cells in the mouse renal pelvis

Iqbal, J., Tonta, M. A., Mitsui, R., Li, Q., Kett, M. M., Li, J., Parkington, H. C., Hashitani, H. & Lang, R. J., 2012, In : British Journal of Pharmacology. 165, 7, p. 2389 - 2408 20 p.

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)

Seeding of endothelial cells on the luminal surface of a sheet model of cold-stored (at 4-degrees C) sheep carotid arteries

Smardencas, A. & Parkington, H., 2012, In : Cell Transplantation: the regenerative medicine journal. 21, 1, p. 285 - 297 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access