• 19 Innovation Walk

    3800 Clayton

    Australia

Accepting PhD Students

1988 …2021
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Research Output 1988 2019

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Article
2019

Genetic editing of colonic organoids provides a molecularly distinct and orthotopic preclinical model of serrated carcinogenesis

Lannagan, T. RM., Lee, Y. K., Wang, T., Roper, J., Bettington, M. L., Fennell, L., Vrbanac, L., Jonavicius, L., Somashekar, R., Gieniec, K., Yang, M., Ng, J. Q., Suzuki, N., Ichinose, M., Wright, J. A., Kobayashi, H., Putoczki, T. L., Hayakawa, Y., Leedham, S. J., Abud, H. E. & 10 others, Yilmaz, Ö. H., Marker, J., Klebe, S., Wirapati, P., Mukherjee, S., Tejpar, S., Leggett, B. A., Whitehall, V. L. J., Worthley, D. L. & Woods, S. L., 7 Mar 2019, In : Gut. 68, 4, p. 684-692 9 p.

Research output: Contribution to journalArticleResearchpeer-review

β-catenin ablation exacerbates polycystic kidney disease progression

Conduit, S. E., Hakim, S., Feeney, S. J., Ooms, L. M., Dyson, J. M., Abud, H. E. & Mitchell, C. A., 15 Jan 2019, In : Human Molecular Genetics. 28, 2, p. 230-244 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2018

Differential expression profiles of conserved Snail transcription factors in the mouse testis

Micati, D. J., Hime, G. R., McLaughlin, E. A., Abud, H. E. & Loveland, K. L., 1 Mar 2018, In : Andrology. 6, 2, p. 362-373 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Diverse bacterial species contribute to antibiotic-associated diarrhoea and gastrointestinal damage

Larcombe, S., Hutton, M. L., Riley, T. V., Abud, H. E. & Lyras, D., Nov 2018, In : Journal of Infection. 77, 5, p. 417-426 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Examination of the ovotoxicity of 5-fluorouracil in mice

Lambouras, M., Liew, S. H., Horvay, K., Abud, H. E., Stringer, J. M. & Hutt, K. J., Jun 2018, In : Journal of Assisted Reproduction and Genetics. 35, 6, p. 1053-1060 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Morphology and function of the lamb ileum following preterm birth

Flores, T. J., Nguyen, V. B., Widdop, R. E., Sutherland, M. R., Polglase, G. R., Abud, H. E. & Black, M. J., 29 Jan 2018, In : Frontiers in Pediatrics. 6, 11 p., 8.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2017

New Monoclonal Antibodies to Defined Cell Surface Proteins on Human Pluripotent Stem Cells

O'Brien, C. M., Chy, H. S., Zhou, Q., Blumenfeld, S., Lambshead, J. W., Liu, X., Kie, J., Capaldo, B. D., Chung, T-L., Adams, T. E., Phan, T., Bentley, J. D., McKinstry, W. J., Oliva, K., McMurrick, P. J., Wang, Y-C., Rossello, F. J., Lindeman, G. J., Chen, D., Jarde, T. & 7 others, Clark, A. T., Abud, H. E., Visvader, J. E., Nefzger, C. M., Polo, J. M., Loring, J. F. & Laslett, A. L., 1 Mar 2017, In : Stem Cells. 35, 3, p. 626-640 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2016

An activated form of ADAM10 is tumor selective and regulates cancer stem-like cells and tumor growth

Atapattu, L., Saha, N., Chheang, C., Eissman, M. F., Xu, K., Vail, M. E., Hii, L., Llerena, C., Liu, Z., Horvay, K., Abud, H. E., Kusebauch, U., Moritz, R. L., Ding, B-S., Cao, Z., Rafii, S., Ernst, M., Scott, A. M., Nikolov, D. B., Lackmann, M. & 1 others, Janes, P. W., 8 Aug 2016, In : Journal of Experimental Medicine. 213, 9, p. 1741-1757 17 p.

Research output: Contribution to journalArticleResearchpeer-review

A Versatile Strategy for Isolating a Highly Enriched Population of Intestinal Stem Cells

Nefzger, C. M., Jarde, T., Rossello, F. J., Horvay, K., Knaupp, A. S., Powell, D. R., Chen, J. Y., Abud, H. E. & Polo, J. M., 2016, In : Stem Cell Reports. 6, 3, p. 321 - 329 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2015

Analyzing stem cell dynamics: use of cutting edge genetic approaches in model organisms

Hime, G. R., Siddall, N., Horvay, K. & Abud, H. E., 2015, In : Frontiers in Biology. 10, 1, p. 1 - 10 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

ERBB3 positively correlates with intestinal stem cell markers but marks a distinct non proliferative cell population in colorectal cancer

Jarde, T., Kass, L., Staples, M., Lescesen, H. E., Carne, P. W. G., Oliva, K., McMurrick, P. J. & Abud, H. E., 2015, In : PLoS ONE. 10, 9 , 16 p., e0138336.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Microarray profiling to analyze the effect of Snai1 loss in mouse intestinal epithelium

Hime, G. R., Horvay, K., Jarde, T., Casagranda, F., Perreau, V. M. & Abud, H. E., 2015, In : Genomics Data. 5, p. 106 - 108 3 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Snai1 regulates cell lineage allocation and stem cell maintenance in the mouse intestinal epithelium

Horvay, K., Jarde, T., Casagranda, F., Perreau, V. M., Haigh, K., Nefzger, C. M., Akhtar, R., Gridley, T., Berx, G., Haigh, J. J., Barker, N., Polo, J. M., Hime, G. R. & Abud, H. E., 2015, In : EMBO Journal. 34, 10, p. 1319 - 1335 17 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2014

Bioactive Functions of Milk Proteins: a Comparative Genomics Approach

Sharp, J. A., Modepalli, V., Enjapoori, A. K., Bisana, S., Abud, H. E., Lefevre, C. M. & Nicholas, K. R., 2014, In : Journal of Mammary Gland Biology and Neoplasia. 19, p. 289 - 302 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Regulated Wnt/beta-catenin signaling sustains adult spermatogenesis in mice

Kerr, G. E., Young, J. C., Horvay, K., Abud, H. E. & Loveland, K. A. L., 2014, In : Biology of Reproduction. 90, 1 (Art. No.:3), p. 1 - 12 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Regulation of cell adhesion int he testis: a new role for p73

Abud, H. E. & Hime, G. R., 2014, In : Asian Journal of Andrology. 16, 6, p. 799 - 800 2 p.

Research output: Contribution to journalArticleOther

RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis

Rickard, J. A., O'Donnell, J. A., Evans, J. M., Lalaoui, N., Poh, A. R., Rogers, T., Vince, J. E., Lawlor, K. E., Ninnis, R. L., Anderton, H., Hall, C., Spall, S. K., Phesse, T. J., Abud, H. E., Cengia, L. H., Corbin, J. E., Mifsud, S., Di Rago, L., Metcalf, D., Ernst, M. R. & 10 others, Dewson, G., Roberts, A. W., Alexander, W. S., Murphy, J. M., Ekert, P. G., Masters, S. L., Vaux, D. L., Croker, B. A., Gerlic, M. & Silke, J., 2014, In : Cell. 157, 5, p. 1175 - 1188 14 p.

Research output: Contribution to journalArticleResearchpeer-review

2013

Genome-wide ENU mutagenesis in combination with high density SNP analysis and exome sequencing provides rapid identification of novel mouse models of developmental disease

Caruana, G., Farlie, P. G., Hart, A. H., Bagheri-Fam, S., Wallace, M. J., Dobbie, M. S., Gordon, C. T., Miller, K. A., Whittle, B., Abud, H. E., Arkell, R. M., Cole, T. J., Harley, V. R., Smyth, I. M. & Bertram, J. F., 2013, In : PLoS ONE. 8, 3, 14 p., e55429.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Hedgehog signalling is downregulated in celiac disease

Liang, R., Hinds, R. M., Abud, H. E. & Cheng, W., 2013, In : Canadian Journal of Gastroenterology. 27, 1, p. e5 - e7 3 p.

Research output: Contribution to journalArticleOtherpeer-review

The Stem Cell State

Hime, G. R. & Abud, H. E., 2013, In : Advances in Experimental Medicine and Biology. 786, p. 1 - 4 4 p.

Research output: Contribution to journalArticleOther

2012

Dmp53 is sequestered to nuclear bodies in spermatogonia of Drosophila melanogaster

Monk, A. C., Abud, H. E. & Hime, G. R., 2012, In : Cell and Tissue Research. 350, 2, p. 385 - 394 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Hedgehog signaling displays a biphasic expression pattern during intestinal injury and repair

Liang, R., Morris, P., Cho, S., Abud, H. E., Jin, X. & Cheng, W., 2012, In : Journal of Pediatric Surgery. 47, p. 2251 - 2263 13 p.

Research output: Contribution to journalArticleResearchpeer-review

2011

Wnt signaling regulates Snai1 expression and cellular localization in the mouse intestinal epithelial stem cell niche

Horvay, K., Casagranda, F., Gany, A., Hime, G. R. & Abud, H. E., 2011, In : Stem Cells and Development. 20, 4, p. 737 - 745 8 p.

Research output: Contribution to journalArticleResearchpeer-review

2010

Genetic dissection of differential signaling threshold requirements for the Wnt/beta-catenin pathway in vivo

Buchert, M., Athineos, D., Abud, H. E., Burke, Z. D., Faux, M. C., Samuel, M. S., Jarnicki, A. G., Winbanks, C. E., Newton, I. P., Meniel, V. S., Suzuki, H., Stacker, S. A., Nathke, I. S., Tosh, D., Huelsken, J., Clarke, A. R., Heath, J. K., Sansom, O. J. & Ernst, M., 2010, In : PLoS Genetics. 6, 1 (e1000816), p. 1 - 13 13 p.

Research output: Contribution to journalArticleResearchpeer-review

2009

Conditional mutations of beta-Catenin and APC reveal roles for canonical Wnt signaling in lens differentiation

Martinez, G., Wijesinghe, M., Turner, K., Abud, H. E., Taketo, M. M., Noda, T., Robinson, M. L. & de Iongh, R. U., 2009, In : Investigative Ophthalmology and Visual Science. 50, 10, p. 4794 - 4806 13 p.

Research output: Contribution to journalArticleResearchpeer-review

2008

Differential requirement for beta-catenin in epithelial and fiber cells during lens development

Cain, S., Martinez, G., Kokkinos, M. I., Turner, K., Richardson, R. J., Abud, H. E., Huelsken, J., Robinson, M. L. & de Iongh, R. U., 2008, In : Developmental Biology. 321, 2, p. 420 - 433 14 p.

Research output: Contribution to journalArticleResearchpeer-review

2007

Drosophila spermatogenesis: Insights into testicular cancer

Hime, G. R., Loveland, K. A. L. & Abud, H. E., 1 Aug 2007, In : International Journal of Andrology. 30, 4, p. 265-274 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
2006

Growing a gut in a petri dish

Abud, H. E. & Layton, M. J., 2006, In : Australasian Science. 27, 8, p. 26 - 28 3 p.

Research output: Contribution to journalArticleOther

WNT/Frizzled signaling in eye development and disease

de Iongh, R. U., Abud, H. E. & Hime, G. R., 2006, In : Frontiers in Bioscience. 11, 1, p. 2442 - 2464 23 p.

Research output: Contribution to journalArticleResearchpeer-review

2005

Growth of intestinal epithelium in organ culture is dependent on EGF signalling

Abud, H. E., Watson, N. & Heath, J. K., 2005, In : Experimental Cell Research. 303, 2, p. 252 - 262 11 p.

Research output: Contribution to journalArticleResearchpeer-review

2004

Efficient gene transfer into the epithelial cell layer of embryonic mouse intestine using low-voltage electroporation

Abud, H. E., Lock, P. & Heath, J. K., 2004, In : Gastroenterology. 126, 7, p. 1779 - 1787 9 p.

Research output: Contribution to journalArticleResearchpeer-review

News and commentary: shaping developing tissues by apoptosis

Abud, H. E., 2004, In : Cell Death and Differentiation. 11, 8, p. 797 - 799 3 p.

Research output: Contribution to journalArticleResearchpeer-review

Shaping developing tissues by apoptosis

Abud, H. E., Aug 2004, In : Cell Death and Differentiation. 11, 8, p. 797-799 3 p.

Research output: Contribution to journalArticleResearchpeer-review

2003

Different daughters: regulation of asymmetric cell division

Hime, G. R., Bunt, S. & Abud, H. E., 2003, In : Australian Biochemist. 34, 1, p. 10 - 13 4 p.

Research output: Contribution to journalArticleOther

2001

Constitutive expression of FGF4 disrupts the development of the eye and the anterior CNS during mouse embryogenesis, but does not influence the expression of shh in these areas

Bueno, D., Abud, H. E., Skinner, J. & Heath, J. K., 2001, In : Belgian Journal of Zoology. 131, 1, p. 57 - 62 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Dynamic expression of alternate splice forms of D-cbl during embryogenesis

Hime, G. R., Abud, H. E., Garner, B., Harris, K-L. & Robertson, H., 2001, In : Mechanisms of Development. 102, 1, p. 235 - 238 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Fibroblast growth factors in the developing central nervous system

Ford-Perriss, M., Abud, H. E. & Murphy, M., 2001, In : Clinical and Experimental Pharmacology and Physiology. 28, 7, p. 493 - 503 11 p.

Research output: Contribution to journalArticleResearchpeer-review

2000

Characterization of mouse A33 antigen, a definitive marker for basolateral surfaces of intestinal epithelial cells

Johnstone, C. N., Tebbutt, N. C., Abud, H. E., White, S. J., Stenvers, K. L., Hall, N. E., Whitehead, R. H., Cody, S. H., Catimel, B., Nice, E. C., Burgess, A. W. & Heath, J. K., 2000, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 279, 3 42-3

Research output: Contribution to journalArticleResearchpeer-review

The murine A33 antigen is expressed at two distinct sites during development, the ICM of the blastocyst and the intestinal epithelium

Abud, H. E., Johnstone, C. N., Tebbutt, N. C. & Heath, J. K., 1 Nov 2000, In : Mechanisms of Development. 98, 1-2, p. 111-114 4 p.

Research output: Contribution to journalArticleResearchpeer-review

1999

Recent applications of instrumental biosensors for protein and peptide structure-function studies

Catimel, B., Domagala, T., Nerrie, M., Weinstock, J., White, S., Abud, H., Heath, J. & Nice, E., 1999, In : Protein and Peptide Letters. 6, 5, p. 319-340 22 p.

Research output: Contribution to journalArticleResearchpeer-review

1998

Early posterior neural tissue is induced by FGF in the chick embryo

Storey, K. G., Goriely, A., Sargent, C. M., Brown, J. M., Burns, H. D., Abud, H. M. & Heath, J. K., Feb 1998, In : Development. 125, 3, p. 473-484 12 p.

Research output: Contribution to journalArticleResearchpeer-review

1997

Isolation of a candidate human telomerase catalytic subunit gene, which reveals complex splicing patterns in different cell types

Kilian, A., Bowtell, D. D. L., Abud, H. E., Hime, G. R., Venter, D. J., Keese, P. K., Duncan, E. L., Reddel, R. R. & Jefferson, R. A., Nov 1997, In : Human Molecular Genetics. 6, 12, p. 2011-2019 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Mutation in Sos1 dominantly enhances a weak allele of the EGFR, demonstrating a requirement for sos1 in EGFR signaling and development

Wang, D. Z. M., Hammond, V. E., Abud, H. E., Bertoncello, I., McAvoy, J. W. & Bowtell, D. D. L., 1 Feb 1997, In : Genes and Development. 11, 3, p. 309-320 12 p.

Research output: Contribution to journalArticleResearchpeer-review

1996

Ectopic expression of Fgf-4 in chimeric mouse embryos induces the expression of early markers of limb development in the lateral ridge

Abud, H. E., Skinner, J. A., Mcdonald, F. J., Bedford, M. T., Lonai, P. & Heath, J. K., 1996, In : Developmental Genetics. 19, 1, p. 51-65 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Multiple functions of fibroblast growth factors in vertebrate development

Abud, H. E., Skinner, J. A., Cohn, M. J. & Heath, J. K., 1996, In : Biochemical Society Symposium. 62, 1, p. 39-50 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Spatial and temporal relationships between Shh, Fgf4, and Fgf8 gene expression at diverse signalling centers during mouse development

Bueno, D., Skinner, J., Abud, H. & Heath, J. K., Nov 1996, In : Developmental Dynamics. 207, 3, p. 291-299 9 p.

Research output: Contribution to journalArticleResearchpeer-review

1995

Fibroblast growth factors induce additional limb development from the flank of chick embryos

Cohn, M. J., Izpisúa-Belmonte, J. C., Abud, H., Heath, J. K. & Tickle, C., 10 Mar 1995, In : Cell. 80, 5, p. 739-746 8 p.

Research output: Contribution to journalArticleResearchpeer-review

1989

A bcr-v-abl oncogene induces lymphomas in transgenic mice

Hariharan, I. K., Harris, A. W., Crawford, M., Abud, H., Webb, E., Cory, S. & Adams, J. M., 1989, In : Molecular and Cellular Biology. 9, 7, p. 2798-2805 8 p.

Research output: Contribution to journalArticleResearchpeer-review

1988

Transgenic mouse models for hematopoietic tumorigenesis.

Harris, A. W., Langdon, W. Y., Alexander, W. S., Hariharan, I. K., Rosenbaum, H., Vaux, D., Webb, E., Bernard, O., Crawford, M. & Abud, H., 1988, In : Current topics in microbiology and immunology. 141, p. 82-93 12 p.

Research output: Contribution to journalArticleResearchpeer-review