Projects per year
Personal profile
Biography
Dr Heidi Fettke is a Postdoctoral Researcher who completed her PhD in prostate cancer genomics at Monash University in 2020. After obtaining a Victorian Cancer Council ECR Postdoctoral Fellowship, she now leads pre-clinical liquid biopsy research associated with advanced prostate cancer trials under the leadership of A/Prof Nguyen-Dumont within the Clinical Genomics group at the Alfred Hospital. Her primary focus and expertise are in liquid biopsy research, circulating tumour DNA, assay R&D, and clinical genomics. She is currently working on identifying ctDNA markers associated with outcomes on novel radionuclide therapy and is accepting students with backgrounds in data science, bioinformatics, clinical genomics or similar.
Research interests
Hormonally-driven cancers (prostate, breast)
Circulating tumour DNA
Blood-based tumour markers
Clinical genomics
Radionuclide therapy/theranostics
Supervision interests
Honours, Masters, Summer/Winter projects
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 1 Finished
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The allopurinol metabolite, oxypurinol, drives oligoclonal expansions of drug-reactive T cells in resolved hypersensitivity cases and drug-naïve healthy donors
Mifsud, N. A., Illing, P. T., Ho, R., Tuomisto, J. E., Fettke, H., Mullan, K. A., McCluskey, J., Rossjohn, J., Vivian, J., Reantragoon, R. & Purcell, A. W., Nov 2023, In: Allergy. 78, 11, p. 2980-2993 14 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access4 Citations (Scopus) -
AlphaBet: Combination of Radium-223 and [177Lu]Lu-PSMA-I&T in men with metastatic castration-resistant prostate cancer (clinical trial protocol)
Kostos, L., Buteau, J. P., Yeung, T., Iulio, J. D., Xie, J., Cardin, A., Chin, K. Y., Emmerson, B., Owen, K. L., Parker, B. S., Fettke, H., Furic, L., Azad, A. A. & Hofman, M. S., 18 Nov 2022, In: Frontiers in Medicine. 9, 13 p., 1059122.Research output: Contribution to journal › Article › Other › peer-review
Open Access25 Citations (Scopus) -
Avelumab Combined with Stereotactic Ablative Body Radiotherapy in Metastatic Castration-resistant Prostate Cancer: The Phase 2 ICE-PAC Clinical Trial
Kwan, E. M., Spain, L., Anton, A., Gan, C. L., Garrett, L., Chang, D., Liow, E., Bennett, C., Zheng, T., Yu, J., Dai, C., Du, P., Jia, S., Fettke, H., Abou-Seif, C., Kothari, G., Shaw, M., Parente, P., Pezaro, C., Tran, B., & 2 others, Mar 2022, In: European Urology. 81, 3, p. 253-262 10 p.Research output: Contribution to journal › Article › Research › peer-review
38 Citations (Scopus) -
Combined impact of lipidomic and genetic aberrations on clinical outcomes in metastatic castration-resistant prostate cancer
Mak, B., Lin, H-M., Kwan, E. M., Fettke, H., Tran, B., Davis, I. D., Mahon, K., Stockler, M. R., Briscoe, K., Marx, G., Zhang, A., Crumbaker, M., Tan, W., Huynh, K., Meikle, T. G., Mellett, N. A., Hoy, A. J., Du, P., Yu, J., Jia, S., & 7 others, Dec 2022, In: BMC Medicine. 20, 1, 14 p., 112.Research output: Contribution to journal › Article › Research › peer-review
Open Access13 Citations (Scopus) -
Carbamazepine Induces Focused T Cell Responses in Resolved Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis Cases But Does Not Perturb the Immunopeptidome for T Cell Recognition
Mifsud, N. A., Illing, P. T., Lai, J. W., Fettke, H., Hensen, L., Huang, Z., Rossjohn, J., Vivian, J. P., Kwan, P. & Purcell, A. W., 12 Apr 2021, In: Frontiers in Immunology. 12, 20 p., 653710.Research output: Contribution to journal › Article › Research › peer-review
Open Access13 Citations (Scopus)